4-nitroquinoline-1-oxide has been researched along with Sensitivity and Specificity in 9 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we performed both assays in 16 established lymphoblastoid cell lines derived from patients with xeroderma pigmentosum (n = 3), ataxia telangiectasia (n = 2), head and neck cancer (n = 3), and melanoma (n = 2), and from normal human subjects (n = 6) using UV light, 4-nitroquinoline-1-oxide (4-NQO; an UV-mimetic agent), and gamma-irradiation as the test agents." | 3.69 | DNA repair capacity correlates with mutagen sensitivity in lymphoblastoid cell lines. ( Cheng, L; Gu, J; Hsu, TC; Kripke, ML; Spitz, MR; Strom, SS; Wei, Q; Xu, X, 1996) |
| " Dose-response relationships were evident in both studies when the data were categorized by quartiles of breaks/cell in the controls, with highest risk estimates being in the top quartile of induced breaks." | 1.29 | Mutagen sensitivity exhibits a dose-response relationship in case-control studies. ( Hsu, TC; Spitz, MR; Wu, X, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hingorani, DV | 1 |
| Lemieux, AJ | 1 |
| Acevedo, JR | 1 |
| Glasgow, HL | 1 |
| Kedarisetty, S | 1 |
| Whitney, MA | 1 |
| Molinolo, AA | 1 |
| Tsien, RY | 1 |
| Nguyen, QT | 1 |
| Kimoto, T | 1 |
| Horibata, K | 1 |
| Chikura, S | 1 |
| Hashimoto, K | 1 |
| Itoh, S | 1 |
| Sanada, H | 1 |
| Muto, S | 1 |
| Uno, Y | 1 |
| Yamada, M | 1 |
| Honma, M | 1 |
| Fixler, D | 1 |
| Ankri, R | 1 |
| Kaplan, I | 1 |
| Novikov, I | 1 |
| Hirshberg, A | 1 |
| Farahati, B | 1 |
| Stachs, O | 1 |
| Prall, F | 1 |
| Stave, J | 1 |
| Guthoff, R | 1 |
| Pau, HW | 1 |
| Just, T | 1 |
| Valentin-Severin, I | 1 |
| Le Hegarat, L | 1 |
| Lhuguenot, JC | 1 |
| Le Bon, AM | 1 |
| Chagnon, MC | 1 |
| Le Curieux, F | 1 |
| Marzin, D | 1 |
| Erb, F | 1 |
| Wu, X | 1 |
| Hsu, TC | 2 |
| Spitz, MR | 2 |
| Wei, Q | 1 |
| Gu, J | 1 |
| Cheng, L | 1 |
| Xu, X | 1 |
| Strom, SS | 1 |
| Kripke, ML | 1 |
| Jenkins, GJ | 1 |
| Chaleshtori, MH | 1 |
| Song, H | 1 |
| Parry, JM | 1 |
9 other studies available for 4-nitroquinoline-1-oxide and Sensitivity and Specificity
| Article | Year |
|---|---|
Early detection of squamous cell carcinoma in carcinogen induced oral cancer rodent model by ratiometric activatable cell penetrating peptides.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell-Penetrating Peptides; | 2017 |
Interlaboratory trial of the rat Pig-a mutation assay using an erythroid marker HIS49 antibody.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; CD59 An | 2013 |
Diffusion Reflection: A Novel Method for Detection of Oral Cancer.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Diffusi | 2014 |
Rigid confocal endoscopy for in vivo imaging of experimental oral squamous intra-epithelial lesions.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma in Situ; Cell Membrane; Cell Nucleus; Dise | 2010 |
Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet As | 2003 |
Comparison of three short-term assays: results on seven chemicals. Potential contribution to the control of water genotoxicity.
Topics: 2-Naphthylamine; 4-Nitroquinoline-1-oxide; Animals; Benzo(a)pyrene; Cyclophosphamide; DNA Damage; En | 1993 |
Mutagen sensitivity exhibits a dose-response relationship in case-control studies.
Topics: 4-Nitroquinoline-1-oxide; Antibiotics, Antineoplastic; Bleomycin; Case-Control Studies; Cell Culture | 1996 |
DNA repair capacity correlates with mutagen sensitivity in lymphoblastoid cell lines.
Topics: 4-Nitroquinoline-1-oxide; Ataxia Telangiectasia; Biomarkers; Carcinogens; Cell Line; Chromatids; Chr | 1996 |
Mutation analysis using the restriction site mutation (RSM) assay.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cells, Cultured; Deoxyribonucleases, Type II Site-Specific; DNA A | 1998 |