Compounds > 4-amino-n-ethyl-n-(beta-hydroxy-ethyl)-m-toluidine
Page last updated: 2024-12-06

4-amino-n-ethyl-n-(beta-hydroxy-ethyl)-m-toluidine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-amino-N-ethyl-N-(beta-hydroxy-ethyl)-m-toluidine: causes allergic contact dermatitis [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID75383
SCHEMBL ID793452
MeSH IDM0364394

Synonyms (21)

Synonym
AKOS005431278
OPREA1_239653
2359-51-5
2-(4-amino-n-ethyl-m-toluidino)ethanol
brn 2721803
einecs 219-104-4
cd 4 color developer
4-amino-n-ethyl-n-(beta-hydroxy-ethyl)-m-toluidine
m-toluidine, 4-amino-n-ethyl-n-(beta-hydroxyethyl)-
2-[(4-amino-3-methylphenyl)(ethyl)amino]ethanol
STK396653
2-(4-amino-n-ethyl-3-methylanilino)ethanol
BBL003986
2-[4-amino(ethyl)-3-methylanilino]-1-ethanol
SCHEMBL793452
n-hydroxyethyl-n-ethyl-3-methyl-p-phenylenediamine
cd-4
ethanol, 2-[(4-amino-3-methylphenyl)ethylamino]-
2-((4-amino-3-methylphenyl)(ethyl)amino)ethanol
CAA35951
DTXSID50865242
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (30.00)18.7374
1990's5 (50.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.88

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.88 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.88)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies5 (45.45%)4.05%
Observational0 (0.00%)0.25%
Other6 (54.55%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
toluene
methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.		3.5990methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
n-methyl-4-aminophenol
4-methylaminophenol : The phenol that is the N-methyl derivative of 4-aminophenol.		1.9810phenolsallergen
cd 3 color developer
CD 3 color developer: used in film laboratories; causes contact dermatitis & lichenoid reactions; RN given refers to parent cpd		3.3770
3-methyl-n,n-diethyl-p-phenylenediamine
3-methyl-N,N-diethyl-p-phenylenediamine: RN given refers to parent cpd; structure		3.2360
ConditionIndicatedRelationship StrengthStudiesTrials
Eczema, Atopic
[description not available]		01.9610
Contact Dermatitis
[description not available]		02.6630
Lichen Ruber Planus
[description not available]		02.3720
Diseases, Occupational
[description not available]		01.9610
Dermatitis, Atopic
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.		01.9610
Dermatitis, Contact
A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.		02.6630
Lichen Planus
An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.		02.3720
Allergic Contact Dermatitis
[description not available]		02.6830
Dermatitis, Occupational
A recurrent contact dermatitis caused by substances found in the work place.		02.8940
Hand Dermatosis
[description not available]		02.3920
Hand Dermatoses
Skin diseases involving the HANDS.		02.3920
Dermatitis, Allergic Contact
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.		02.6830
Licheniform Eruptions
[description not available]		01.9810
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		0210
Burns, Chemical
Burns caused by contact with or exposure to CAUSTICS or strong ACIDS.		01.9710