Proteins > Solute carrier organic anion transporter family member 2A1
Page last updated: 2024-08-08 00:08:20
Solute carrier organic anion transporter family member 2A1
A solute carrier organic anion transporter family member 2A1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q92959]
Synonyms
Prostaglandin transporter;
PGT;
Solute carrier family 21 member 2
Research
Bioassay Publications (4)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (12)
Drugs with Inhibition Measurements
Drugs with Other Measurements
Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities.The American journal of physiology, , Volume: 277, Issue:3, 1999
Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT).The Journal of clinical investigation, , Sep-01, Volume: 98, Issue:5, 1996
Cloning of mouse prostaglandin transporter PGT cDNA: species-specific substrate affinities.The American journal of physiology, , Volume: 277, Issue:3, 1999
Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT).The Journal of clinical investigation, , Sep-01, Volume: 98, Issue:5, 1996
Enables
This protein enables 3 target(s):
Target | Category | Definition |
lipid transporter activity | molecular function | Enables the directed movement of lipids into, out of or within a cell, or between cells. [GOC:ai] |
prostaglandin transmembrane transporter activity | molecular function | Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities. [GOC:ai] |
sodium-independent organic anion transmembrane transporter activity | molecular function | Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner. [GOC:go_curators] |
Located In
This protein is located in 4 target(s):
Target | Category | Definition |
lysosome | cellular component | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. [GOC:mah, ISBN:0198506732] |
plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
basal plasma membrane | cellular component | The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
Active In
This protein is active in 1 target(s):
Target | Category | Definition |
basolateral plasma membrane | cellular component | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
Involved In
This protein is involved in 4 target(s):
Target | Category | Definition |
lipid transport | biological process | The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [ISBN:0198506732] |
sodium-independent organic anion transport | biological process | The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:go_curators] |
transmembrane transport | biological process | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. [GOC:dph, GOC:jid] |
prostaglandin transport | biological process | The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc] |