Assay ID | Title | Year | Journal | Article |
AID1100805 | Antifungal activity against Magnaporthe grisea VIAM MA1627 assessed as inhibition of spore germination by microdilution technique linked with digital image analysis | 2000 | Journal of agricultural and food chemistry, Apr, Volume: 48, Issue:4
| Cyclopenta[b]benzofurans from Aglaia species with pronounced antifungal activity against rice blast fungus (Pyricularia grisea). |
AID733969 | Cytotoxicity against human HT-29 cells | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3
| Bioactive flavaglines and other constituents isolated from Aglaia perviridis. |
AID430792 | Cytotoxicity against human KB cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430804 | Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID379690 | Cytotoxicity against mouse WEHI164 cells | 2000 | Journal of natural products, Apr, Volume: 63, Issue:4
| Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora. |
AID1100804 | Antifungal activity against Alternaria citri CBS 192.81; VIAM MA1628 assessed as inhibition of spore germination by microdilution technique linked with digital image analysis | 2000 | Journal of agricultural and food chemistry, Apr, Volume: 48, Issue:4
| Cyclopenta[b]benzofurans from Aglaia species with pronounced antifungal activity against rice blast fungus (Pyricularia grisea). |
AID354876 | Growth inhibition of mouse NIH/3T3 cells | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430798 | Inhibition of P-glycoprotein expressing human MCF7 cells assessed as change in rhodamine 123 efflux at 0.1 to 1 uM | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430794 | Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430808 | Cell cycle arrest in human HL60 cells assessed as increase in G0/G1 peak at 200 nM after 48 hrs by FACS analysis | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID354869 | Induction of morphological changes in rat NRK cells expressing K-ras assessed as flat morphology and cytoskeletal organization at 10 to 30 ng/mL after 1 day | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430797 | Cytotoxicity against human HL60 cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID354867 | Inhibition of RNA synthesis in rat NRK cells expressing K-ras assessed as [5-3H]uridine incorporation after 1 hr | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID379691 | Cytotoxicity against mouse LL/2 cells | 2000 | Journal of natural products, Apr, Volume: 63, Issue:4
| Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora. |
AID1100802 | Antifungal activity against Alternaria citri CBS 192.81; VIAM MA1628 assessed as inhibition of spore germination at 200 ug/ml by microdilution technique linked with digital image analysis | 2000 | Journal of agricultural and food chemistry, Apr, Volume: 48, Issue:4
| Cyclopenta[b]benzofurans from Aglaia species with pronounced antifungal activity against rice blast fungus (Pyricularia grisea). |
AID354875 | Growth inhibition of rat NRK cells | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430795 | Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID379692 | Cytotoxicity against mouse P388 cells | 2000 | Journal of natural products, Apr, Volume: 63, Issue:4
| Flavonol-cinnamate cycloadducts and diamide derivatives from Aglaia laxiflora. |
AID733968 | Cytotoxicity against human CCD-112CoN cells | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3
| Bioactive flavaglines and other constituents isolated from Aglaia perviridis. |
AID430796 | Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430800 | Induction of apoptosis in rat H9c2 cells at 0.5 to 50 nM after 24 hrs by FACS analysis | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID354868 | Decrease in cellular Ras protein level in rat NRK cells expressing K-ras at 2.5 ng/mL after 1 to 3 days by immunoblotting | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID354874 | Growth inhibition of mouse NIH/3T3 cells expressing N-ras | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430818 | Antiproliferative activity against human HL60 cells at 50 nM in presence of necroptosis inhibitor 3-methyladenine | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID448438 | Inhibition of NF-kappaB activation | 2009 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 19, Issue:19
| The first pharmacophore model for potent NF-kappaB inhibitors. |
AID1100803 | Antifungal activity against Fusarium avenaceum VIAM MA1512 assessed as inhibition of spore germination by microdilution technique linked with digital image analysis | 2000 | Journal of agricultural and food chemistry, Apr, Volume: 48, Issue:4
| Cyclopenta[b]benzofurans from Aglaia species with pronounced antifungal activity against rice blast fungus (Pyricularia grisea). |
AID430799 | Enhancement of doxorubicin-induced cytotoxicity against human HepG2 cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430811 | Induction of apoptosis in human HL60 cells assessed as caspase 3/7-mediated DEVD-AMC substrate cleavage at 1 to 1000 nM after 48 hrs by spectroscopy | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430817 | Antiproliferative activity against human HL60 cells at 50 nM in presence of autophagy inhibitor necrostatin 1 | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430793 | Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID733967 | Inhibition of NF-kappaB p65 (unknown origin) by ELISA | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3
| Bioactive flavaglines and other constituents isolated from Aglaia perviridis. |
AID354872 | Growth inhibition of mouse NIH/3T3 cells expressing K-ras | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430807 | Cell cycle arrest in human HL60 cells assessed as accumulation of cells in G2/M phase at 20 nM after 48 hrs by FACS analysis | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID354870 | Induction of morphological changes in rat NRK cells expressing K-ras assessed as flat morphology and cytoskeletal organization at 10 to 30 ng/mL after 3 days | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430806 | Cell cycle arrest in human HL60 cells assessed as accumulation of cells in G2/M phase at 200 nM after 48 hrs by FACS analysis | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID354866 | Inhibition of DNA synthesis in rat NRK cells expressing K-ras assessed as [methyl-3H]thymidine incorporation after 1 hr | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430816 | Antiproliferative activity against human HL60 cells at 50 nM in presence of caspase inhibitor Z-VAD-FMK | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID430819 | Inhibition of proteasome activity in human HL60 cells at 20 to 200 nM | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
AID354873 | Growth inhibition of mouse NIH/3T3 cells expressing H-ras | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID354865 | Inhibition of protein synthesis in rat NRK cells expressing K-ras assessed as L-[4,5-3H]leucine incorporation after 1 hr | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID354871 | Growth inhibition of rat NRK cells expressing K-ras | 1996 | Journal of natural products, Jul, Volume: 59, Issue:7
| Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. |
AID430809 | Cell cycle arrest in human HL60 cells assessed as increase in G0/G1 peak at 20 nM after 48 hrs by FACS analysis | 2009 | Journal of medicinal chemistry, Aug-27, Volume: 52, Issue:16
| Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |