Page last updated: 2024-12-07

1,5(10)-estradiene-3,4,17-trione

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,5(10)-estradiene-3,4,17-trione: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

estra-1,5(10)-diene-3,4,17-trione : An o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 4-hydroxyestrone. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID114862
CHEBI ID87263
MeSH IDM0129303

Synonyms (18)

Synonym
1,5(10)estradiene-3,14,17-trione
3,4-estrone quinone
estra-1,5(10)-diene-3,4,17-trione
1,5(10)-estradiene-3,4,17-trione
ccris 7598
40551-34-6
unii-3u2v78om3m
3,4-estrone-o-quinone
3u2v78om3m ,
CHEBI:87263
3,4-estronequinone
(8r,9s,13s,14s)-13-methyl-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta(a)phenanthrene-3,4,17-trione
j528.646h ,
3,4-estrone ortho-quinone
3,4-estrone o-quinone
3,4-estrogen o-quinone
Q20739847
DTXSID30960966
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
human metaboliteAny mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
orthoquinonesAny quinone in which the carbons of the two carbonyl groups in the quinone system are joined to each other by a single bond.
17-oxo steroidAny oxo steroid carrying the oxo group at position 17.
3-oxo-Delta(1) steroidAny 3-oxo steroid that contains a double bond between positions 1 and 2.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

PathwayProteinsCompounds
Estrogen metabolism025

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (10.00)18.7374
1990's8 (80.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.44

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.44 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index5.15 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.44)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]