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aldosterone and Sensitivity and Specificity

aldosterone has been researched along with Sensitivity and Specificity in 166 studies

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"The objective of the study was to compare the sensitivity and specificity of (11)C-metomidate PET-computed tomography (CT) against the current gold standard of AVS."9.16Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas. ( Aigbirhio, F; Azizan, EA; Balan, K; Bird, N; Brown, MJ; Burton, TJ; Gurnell, M; Koo, B; Mackenzie, IS; Soloviev, DV, 2012)
"A common pharmacologic test for the diagnosis of primary aldosteronism (PA) is the administration of captopril to determine whether an abnormal plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio(ARR) persists, although active renin concentration (ARC) may offer advantages with regard to processing and standardization."9.14Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity. ( Chang, CC; Chang, HW; Chueh, SC; Fang, CC; Ho, YL; Huang, KH; Kuo, CC; Lin, CY; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yen, RF, 2010)
"In forty six hypertensive patients in whom a high level of clinical suspicion for renovascular hypertension was present on the basis of clinical clues, a captopril test was performed with either 25 mg of captopril or placebo on 2 separate days to determine prospectively the value of the captopril test."9.08'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis. ( de Leeuw, PW; Lavrijssen, AT; Schiffers, PM; Schreij, G; van Es, PN, 1995)
"Captopril challenge test (CCT) is a simple and safe confirmatory test for primary aldosteronism (PA)."8.02Prediction of unilateral hyperaldosteronism on adrenal vein sampling using captopril challenge test in patients with primary aldosteronism. ( Baba, S; Miyoshi, A; Obara, S; Shibayama, Y; Sugawara, H; Takahashi, B; Terae, S; Usubuchi, H; Wada, N, 2021)
"The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA)."7.91The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population. ( Feng, WH; Li, HY; Li, P; Zhang, WJ; Zhang, Y; Zhu, DL; Zhu, KY, 2019)
"Imaging with [¹²³I]iodometomidate ([¹²³I]IMTO) has been shown to diagnose adrenocortical lesions with high sensitivity and specificity."7.79[¹²³I]Iodometomidate imaging in adrenocortical carcinoma. ( Allolio, B; Bock, S; Buck, AK; Fassnacht, M; Haenscheid, H; Hahner, S; Knoedler, P; Kreissl, MC; Reiners, C; Saeger, W; Schirbel, A; Verburg, FA, 2013)
" Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity."7.78Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012)
"An increased sensitivity to angiotensin II (Ang II) has been observed in patients with established hypertension."7.71Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. ( Delles, C; Jacobi, J; Klingbeil, AU; Schlaich, MP; Schmidt, BM; Schmieder, RE; Schneider, MP, 2002)
"Plasma concentrations of renin and aldosterone were measured before and 60 min after taking 25 mg captopril in 242 patients with arterial hypertension (124 men, 118 women, aged 51."7.68[Does the captopril test improve the diagnosis of primary hyperaldosteronism?]. ( Bönner, G; Degenhardt, S; Grimm, U; Krone, W; Stimpel, M; Wambach, G, 1992)
"Application of the captopril test to patients identified as abnormal by screening confirms all cases of primary hyperaldosteronism but false positive or equivocal results, necessitating further investigation, may occur in some patients with essential hypertension."7.68Re-evaluation of the captopril test for the diagnosis of primary hyperaldosteronism. ( Bartlett, WA; Browning, MC; Gunn, A; Hambling, C; Jung, RT, 1992)
"Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension."6.70Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002)
"Idiopathic hyper-aldosteronism was diagnosed on the basis of the results of dexamethasone-suppressed adrenal scintigraphy and/or selective adrenal vein sampling."6.67Imaging of aldosterone-secreting adenomas: a prospective comparison of computed tomography and magnetic resonance imaging in 27 patients with suspected primary aldosteronism. ( Chiesura-Corona, M; Feltrin, GP; Pelizzo, MR; Perale, R; Pessina, AC; Rossi, GP; Soattin, S; Tregnaghi, A; Zanin, L, 1993)
"Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (3%-32% of hypertensive patients)."6.61The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges. ( Denieffe, S; Fitzgibbon, MC; Griffin, TP; O'Shea, PM, 2019)
"Primary aldosteronism is an underdiagnosed cause of hypertension."5.62Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection. ( Fudim, T; Hundemer, GL; Moussa, M; Sacks, B; Underhill, J; Vaidya, A; Yozamp, N, 2021)
"Primary aldosteronism is recognized as the most frequent cause of secondary hypertension, and its screening is expected to become a routine evaluation in most patients with hypertension."5.56Renin-Angiotensin-Aldosterone System Triple-A Analysis for the Screening of Primary Aldosteronism. ( Buffolo, F; Burrello, J; Domenig, O; Monticone, S; Mulatero, P; Pecori, A; Poglitsch, M; Tetti, M, 2020)
"Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays."5.48Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism. ( Ahmed, AH; Gordon, RD; Guo, Z; McWhinney, BC; Poglitsch, M; Stowasser, M; Ungerer, JPJ; Wolley, M, 2018)
"Of the two of 20 primary aldosteronism patients missed by AARR, none resulted affected by APA."5.43Diagnostic accuracy of aldosterone and renin measurement by chemiluminescent immunoassay and radioimmunoassay in primary aldosteronism. ( Buffolo, F; Burrello, J; Lucchiari, M; Mengozzi, G; Monticone, S; Mulatero, P; Rabbia, F; Tetti, M; Veglio, F; Williams, TA, 2016)
"Our data indicate that in mice with Liddle syndrome, the primary site of increased Na(+) reabsorption is the DCT2/CNT."5.43In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron. ( Bertog, M; Dahlmann, A; Korbmacher, C; Krueger, B; Nesterov, V; Palmisano, R, 2016)
"ARR sensitivity for primary aldosteronism is low when the recommended cut-off is used."5.40Test characteristics of the aldosterone-to-renin ratio as a screening test for primary aldosteronism. ( Danser, AH; de Bruijne, EL; Deinum, J; Frenkel, WJ; Jansen, PM; Kerstens, MN; Smulders, YM; van den Born, BJ; van den Meiracker, AH; Wijbenga, JA; Woittiez, AJ; Zietse, R, 2014)
"In candesartan-treated db/db mice (1 mg/kg per day, 4 weeks) increased plasma aldosterone, CYP11B2 expression, and aldosterone secretion were reduced."5.38Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction. ( Briones, AM; Burger, D; Burns, KD; Callera, GE; Corrêa, JW; Gagnon, AM; Gomez-Sanchez, CE; Gomez-Sanchez, EP; He, Y; Nguyen Dinh Cat, A; Ooi, TC; Ruzicka, M; Sorisky, A; Touyz, RM; Yogi, A, 2012)
"The prevalence of primary aldosteronism (PA) was assessed in a specialized hypertension center."5.31High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. ( Davoli, S; Negro, A; Perazzoli, F; Regolisti, G; Rossi, E; Sani, C, 2002)
"In primary hyperaldosteronism, it is important to distinguish between unilateral and bilateral disease, as management strategies differ."5.30Accuracy of CT scanning and adrenal vein sampling in the pre-operative localization of aldosterone-secreting adrenal adenomas. ( Atkinson, AB; Ferrett, CG; Harper, R; McIlrath, EM; McKnight, JA; Russell, CF; Sheridan, B, 1999)
"Primary aldosteronism, though an uncommon cause of hypertension, causes significant morbidity, making it important to diagnose and treat this condition."5.30Aldosterone to renin ratios in the evaluation of primary aldosteronism. ( Eng, PH; Fok, AC; Ho, SC; Khoo, DH; Koh, LK; Lim, HS; Lim, SC; Tai, ES; Tan, CE; Tan, KE, 1997)
"The objective of the study was to compare the sensitivity and specificity of (11)C-metomidate PET-computed tomography (CT) against the current gold standard of AVS."5.16Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas. ( Aigbirhio, F; Azizan, EA; Balan, K; Bird, N; Brown, MJ; Burton, TJ; Gurnell, M; Koo, B; Mackenzie, IS; Soloviev, DV, 2012)
"A common pharmacologic test for the diagnosis of primary aldosteronism (PA) is the administration of captopril to determine whether an abnormal plasma aldosterone concentration (PAC) to plasma renin activity (PRA) ratio(ARR) persists, although active renin concentration (ARC) may offer advantages with regard to processing and standardization."5.14Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity. ( Chang, CC; Chang, HW; Chueh, SC; Fang, CC; Ho, YL; Huang, KH; Kuo, CC; Lin, CY; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yen, RF, 2010)
"Our results showed that adrenal insufficiency of any cause was adequately diagnosed using the response of 11-deoxycortisol, dehydroepiandrosterone, or these analytes combined in a two-steroid profile."5.12Use of steroid profiles in determining the cause of adrenal insufficiency. ( Guo, T; Holst, JP; Jonklaas, J; Kundra, P; Soldin, SJ; Tractenberg, RE; Verbalis, JG, 2007)
"In forty six hypertensive patients in whom a high level of clinical suspicion for renovascular hypertension was present on the basis of clinical clues, a captopril test was performed with either 25 mg of captopril or placebo on 2 separate days to determine prospectively the value of the captopril test."5.08'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis. ( de Leeuw, PW; Lavrijssen, AT; Schiffers, PM; Schreij, G; van Es, PN, 1995)
"Captopril challenge test (CCT) is a simple and safe confirmatory test for primary aldosteronism (PA)."4.02Prediction of unilateral hyperaldosteronism on adrenal vein sampling using captopril challenge test in patients with primary aldosteronism. ( Baba, S; Miyoshi, A; Obara, S; Shibayama, Y; Sugawara, H; Takahashi, B; Terae, S; Usubuchi, H; Wada, N, 2021)
"The Captopril challenge test (CCT) is an easy-conduct confirmatory test for diagnosing primary aldosteronism (PA)."3.91The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population. ( Feng, WH; Li, HY; Li, P; Zhang, WJ; Zhang, Y; Zhu, DL; Zhu, KY, 2019)
"Imaging with [¹²³I]iodometomidate ([¹²³I]IMTO) has been shown to diagnose adrenocortical lesions with high sensitivity and specificity."3.79[¹²³I]Iodometomidate imaging in adrenocortical carcinoma. ( Allolio, B; Bock, S; Buck, AK; Fassnacht, M; Haenscheid, H; Hahner, S; Knoedler, P; Kreissl, MC; Reiners, C; Saeger, W; Schirbel, A; Verburg, FA, 2013)
"Idiopathic primary hyperaldosteronism (IHA) and low-renin essential hypertension (LREH) are common forms of hypertension, characterized by an elevated aldosterone-renin ratio and hypersensitivity to angiotensin II."3.78TASK-3 channel deletion in mice recapitulates low-renin essential hypertension. ( Barrett, PQ; Bayliss, DA; Carey, RM; Guagliardo, NA; Hu, C; Schertz, EM; Tyson, DA; Yao, J, 2012)
" Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity."3.78Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012)
"An increased sensitivity to angiotensin II (Ang II) has been observed in patients with established hypertension."3.71Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. ( Delles, C; Jacobi, J; Klingbeil, AU; Schlaich, MP; Schmidt, BM; Schmieder, RE; Schneider, MP, 2002)
"Application of the captopril test to patients identified as abnormal by screening confirms all cases of primary hyperaldosteronism but false positive or equivocal results, necessitating further investigation, may occur in some patients with essential hypertension."3.68Re-evaluation of the captopril test for the diagnosis of primary hyperaldosteronism. ( Bartlett, WA; Browning, MC; Gunn, A; Hambling, C; Jung, RT, 1992)
"Plasma concentrations of renin and aldosterone were measured before and 60 min after taking 25 mg captopril in 242 patients with arterial hypertension (124 men, 118 women, aged 51."3.68[Does the captopril test improve the diagnosis of primary hyperaldosteronism?]. ( Bönner, G; Degenhardt, S; Grimm, U; Krone, W; Stimpel, M; Wambach, G, 1992)
"Primary hyperaldosteronism was confirmed if plasma renin activity was <1."2.70Hyperaldosteronism among black and white subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Thakkar, RB; Weissmann, P; Zaman, MA, 2002)
"Primary aldosteronism is a specifically treatable and potentially curable form of secondary hypertension."2.70Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. ( Chiandussi, L; Milan, A; Morello, F; Mulatero, P; Paglieri, C; Rabbia, F; Veglio, F, 2002)
"Idiopathic hyper-aldosteronism was diagnosed on the basis of the results of dexamethasone-suppressed adrenal scintigraphy and/or selective adrenal vein sampling."2.67Imaging of aldosterone-secreting adenomas: a prospective comparison of computed tomography and magnetic resonance imaging in 27 patients with suspected primary aldosteronism. ( Chiesura-Corona, M; Feltrin, GP; Pelizzo, MR; Perale, R; Pessina, AC; Rossi, GP; Soattin, S; Tregnaghi, A; Zanin, L, 1993)
"Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (3%-32% of hypertensive patients)."2.61The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges. ( Denieffe, S; Fitzgibbon, MC; Griffin, TP; O'Shea, PM, 2019)
"In view of the fact that primary aldosteronism (PA) is a problem that is more prevalent than previously thought and its diagnosis is of greater clinical significance than previously believed, the Endocrine Society has recently published recommendations on the diagnosis and management of PA."2.48Primary aldosteronism: a common and important problem. A practical guide to the diagnosis and treatment. ( Górska, M; Myśliwiec, J, 2012)
"Primary aldosteronism (PA) is a form of surgically curable secondary hypertension."2.43[Screening tests and diagnostic examinations of hypertensives for primary aldosteronism]. ( Nishikawa, T; Omura, M, 2006)
"Primary aldosteronism is an underdiagnosed cause of hypertension."1.62Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection. ( Fudim, T; Hundemer, GL; Moussa, M; Sacks, B; Underhill, J; Vaidya, A; Yozamp, N, 2021)
"In 15 primary aldosteronism patients, we performed intraoperative endoscopic ultrasound, ex vivo magnetic resonance imaging and histopathological examination."1.62Partial Adrenalectomy Carries a Considerable Risk of Incomplete Cure in Primary Aldosteronism. ( Aalders, TW; Deinum, J; Küsters, B; Langenhuijsen, JF; Mann, R; Mukai, K; van de Wiel, ECJ; Veltien, A; Verhaegh, GW, 2021)
"Primary aldosteronism (PA) is the most frequent cause of secondary hypertension."1.56Construction of a predictive scoring system as a guide to screening and confirmation of the diagnosis of primary aldosteronism. ( Kietsiriroje, N; Murray, RD; Suntornlohanakul, O; Wonghirundecha, R, 2020)
"Primary aldosteronism is recognized as the most frequent cause of secondary hypertension, and its screening is expected to become a routine evaluation in most patients with hypertension."1.56Renin-Angiotensin-Aldosterone System Triple-A Analysis for the Screening of Primary Aldosteronism. ( Buffolo, F; Burrello, J; Domenig, O; Monticone, S; Mulatero, P; Pecori, A; Poglitsch, M; Tetti, M, 2020)
"Unilateral primary aldosteronism is surgically curable."1.51Primary aldosteronism with nonlocalizing imaging. ( Bhandari, S; Cohen, DL; Fraker, DL; Roses, RE; Trerotola, SO; Wachtel, H, 2019)
"Risk factors for idiopathic hyperaldosteronism (IHA) differentiating from aldosterone-producing adenoma (APA) were identified using logistic regression analysis."1.51A novel clinical nomogram to predict bilateral hyperaldosteronism in Chinese patients with primary aldosteronism. ( Jiang, L; Jiang, Y; Ning, G; Su, T; Wang, W; Xiao, L; Zhang, C; Zhou, W, 2019)
"The diagnostic workup for primary aldosteronism includes a screening step using the aldosterone-to-renin ratio (ARR) and a confirmatory step based on dynamic testing of aldosterone secretion autonomy."1.51Evaluation of Biochemical Conditions Allowing Bypass of Confirmatory Testing in The Workup of Primary Aldosteronism: A Retrospective Study in a French Hypertensive Population. ( Deberles, E; Guenet, D; Haddouche, A; Morello, R; Reznik, Y; Vivien, M, 2019)
"The diagnosis of primary aldosteronism typically requires at least one confirmatory test."1.48Confirmatory Tests for the Diagnosis of Primary Aldosteronism: A Prospective Diagnostic Accuracy Study. ( Bruemmer, D; Cheng, Q; He, W; Hu, J; Li, Q; Luo, T; Ma, L; Mei, M; Peng, B; Qing, H; Song, Y; Wang, Y; Wang, Z; Yang, S; Zhang, S; Zhen, Q, 2018)
"Current threshold values for primary aldosteronism (PA) diagnostic testing are based on measuring aldosterone (PAC) using immunoassays."1.48Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism. ( Ahmed, AH; Gordon, RD; Guo, Z; McWhinney, BC; Poglitsch, M; Stowasser, M; Ungerer, JPJ; Wolley, M, 2018)
"Functional hypoaldosteronism had appreciated in 18/29 (62%) patients, whereas 11 patients (38%) had normal postoperative aldosterone."1.46Considering Postoperative Functional Hypoaldosteronism after Unilateral Adrenalectomy. ( Christakis, I; Graham, P; Grubbs, EG; Julien, JS; Lee, JE; Perrier, ND; Schwarz, K; Starker, LF, 2017)
"Subclinical hypercortisolism (SH) occurs in 5% to 30% of adrenal incidentalomas (AIs)."1.46Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas. ( Annamalai, AK; Dennedy, MC; Freeman, N; Graggaber, J; Gurnell, M; Halsall, DJ; Koulouri, O; Powlson, AS; Prankerd-Smith, O; Shaw, A; Vengopal, K, 2017)
"Of the two of 20 primary aldosteronism patients missed by AARR, none resulted affected by APA."1.43Diagnostic accuracy of aldosterone and renin measurement by chemiluminescent immunoassay and radioimmunoassay in primary aldosteronism. ( Buffolo, F; Burrello, J; Lucchiari, M; Mengozzi, G; Monticone, S; Mulatero, P; Rabbia, F; Tetti, M; Veglio, F; Williams, TA, 2016)
"Aldosterone/renin ratio was elevated in 99 patients of whom 31 exhibited elevated supine aldosterone, as well."1.43[Renin and aldosterone determinations in hypertensive patients]. ( Bajnok, L; Bódis, B; Hussein, T; Mezősi, E; Nemes, O; Rucz, K, 2016)
"5% respectively) when supine ARR cut-off point were used in combination with supine PAC over 329."1.43[An evaluation of plasma aldosterone-to-active-renin ratio in different postures in combination with aldosterone concentration in the diagnosis of aldosteronoma]. ( Ba, JM; Dou, JT; Gu, WJ; Guo, QH; Jin, N; Lyu, ZH; Mu, YM; Wang, XL; Yang, GQ; Yang, LJ; Zang, L; Zhu, J, 2016)
"In patients with suspected primary aldosteronism (PA), the first diagnostic step, screening, must have high sensitivity and negative predictive value."1.43SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps. ( Douillard, C; Girerd, X; Houillier, P; Nussberger, J, 2016)
"Our data indicate that in mice with Liddle syndrome, the primary site of increased Na(+) reabsorption is the DCT2/CNT."1.43In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron. ( Bertog, M; Dahlmann, A; Korbmacher, C; Krueger, B; Nesterov, V; Palmisano, R, 2016)
"Primary aldosteronism (PA) is the most common cause of endocrine hypertension that is diagnosed following a two-step process: an initial screening test, based on the serum aldosterone-to-renin ratio (ARR), followed by a relatively laborious and time-consuming confirmatory test to document autonomous aldosterone (ALD) secretion."1.43A new highly sensitive and specific overnight combined screening and diagnostic test for primary aldosteronism. ( Androulakis, II; Chrousos, GP; Kaltsas, G; Kassi, E; Kounadi, T; Markou, A; Papanastasiou, L; Piaditis, GP; Tsiavos, V; Voulgaris, N; Zachaki, A, 2016)
"Aldosterone/renin ratio was calculated as aldosterone concentration/renin activity."1.43Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families. ( Bunker, CH; Kammerer, CM; Kuipers, AL; Patrick, AL; Pratt, JH; Wheeler, VW; Zmuda, JM, 2016)
"Aldosterone suppression was assessed in 73 essential hypertensive and 46 primary aldosteronism patients."1.42Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays. ( Bidlingmaier, M; Diederich, S; Dietz, A; Fischer, E; Grimminger, P; Holmes, D; Junnila, R; Manolopoulou, J; Morganti, A; Reincke, M, 2015)
"Primary aldosteronism (PA) is characterized by the autonomous overproduction of aldosterone."1.42Screening for primary aldosteronism in an argentinian population: a multicenter prospective study. ( Belli, SH; Chervin, RA; Contreras, LN; Cornaló, D; Costa, L; Damilano, SA; Fenili, CA; Gómez, RM; Leal Reyna, M; Lupi, SN; Martínez, MS; Nofal, MT; Pardes, EM; Rossi, MA; Ruibal, GF, 2015)
"Primary aldosteronism and particularly its most caricatural form, that is APA, seems associated with a lower level of prorenin than essential hypertension."1.42Decreased plasma prorenin levels in primary aldosteronism: potential diagnostic implications. ( Berge, C; Bricca, G; Courand, PY; Fauvel, JP; Harbaoui, B; Khettab, F; Lantelme, P; Paget, V, 2015)
"Primary aldosteronism (PA) is estimated to occur in 5-12% of patients with hypertension."1.42The ratios of aldosterone / plasma renin activity (ARR) versus aldosterone / direct renin concentration (ADRR). ( Bednarek-Papierska, L; Gietka-Czernel, M; Glinicki, P; Jeske, W; Kasperlik-Załuska, A; Kruszyńska, A; Rosłonowska, E; Słowińska-Srzednicka, J; Zgliczyński, W, 2015)
"A review of patients with primary aldosteronism from June 2005 to July 2013 at a single center's hypertension clinic."1.40A clinical prediction score for diagnosing unilateral primary aldosteronism may not be generalizable. ( Dias, VC; Harvey, A; Kline, GA; Pasieka, JL; So, B; Venos, ES, 2014)
"ARR sensitivity for primary aldosteronism is low when the recommended cut-off is used."1.40Test characteristics of the aldosterone-to-renin ratio as a screening test for primary aldosteronism. ( Danser, AH; de Bruijne, EL; Deinum, J; Frenkel, WJ; Jansen, PM; Kerstens, MN; Smulders, YM; van den Born, BJ; van den Meiracker, AH; Wijbenga, JA; Woittiez, AJ; Zietse, R, 2014)
"Aldosterone is a mineralocorticoid steroid hormone whose measurement in the clinical laboratory is principally performed for the investigation of primary hyperaldosteronism."1.39Quantitation of aldosterone in human plasma by ultra high performance liquid chromatography tandem mass spectrometry. ( Carter, S; Hinchliffe, E; Keevil, BG; Owen, LJ, 2013)
"In candesartan-treated db/db mice (1 mg/kg per day, 4 weeks) increased plasma aldosterone, CYP11B2 expression, and aldosterone secretion were reduced."1.38Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction. ( Briones, AM; Burger, D; Burns, KD; Callera, GE; Corrêa, JW; Gagnon, AM; Gomez-Sanchez, CE; Gomez-Sanchez, EP; He, Y; Nguyen Dinh Cat, A; Ooi, TC; Ruzicka, M; Sorisky, A; Touyz, RM; Yogi, A, 2012)
"We tested this in 2 animal models of aldosteronism (aldosterone infusion or low-sodium diet) and in patients with primary aldosteronism."1.38The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism. ( Danser, AH; Fenton, RA; Hoorn, EJ; Jansen, PM; Salih, M; van den Meiracker, AH; van der Lubbe, N; Zietse, R, 2012)
"Twenty-nine ESRD patients with sustained hypotension were investigated for possible AI."1.35Diagnostic value of salivary cortisol in end stage renal disease. ( Arregger, AL; Cardoso, EM; Contreras, LN; Tumilasci, O, 2008)
"Aldosterone was also measured by RIA."1.35Determination of aldosterone in serum by liquid chromatography-tandem mass spectrometry. ( Hämäläinen, E; Stenman, UH; Turpeinen, U, 2008)
"Fludrocortisone was administered 4 times daily over 4 days and sodium chloride was supplemented in 3 different doses."1.35Re-evaluation of the fludrocortisone test: duration, NaCl supplementation and cut-off limits for aldosterone. ( Bergenfelz, A; Isaksson, A; Larsson, J; Nerbrand, C; Valdemarsson, S; Westerdahl, C; Wihl, A, 2009)
"Metabolic syndrome is a highly predisposing condition for cardiovascular disease and could be a cause of excess salt-induced organ damage."1.35Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder. ( Ando, K; Fujita, M; Fujita, T; Kawarazaki, H; Matsui, H; Nagae, A; Nagase, M; Shimosawa, T, 2008)
"Thus, a reliable screening test for primary hyperaldosteronism (PA) is essential to avoid unnecessary diagnostic procedures to this population."1.34The aldosterone to renin ratio in the evaluation of patients with incidentally detected adrenal masses. ( Botoula, E; Effraimidis, G; Effremidis, G; Gavalas, N; Szabo, A; Thalassinos, NC; Tzanela, M; Valatsou, A; Vassiliadi, D, 2007)
"Primary aldosteronism (PA) is the most frequent form of secondary hypertension, accounting for up to 5-10% of all hypertensive patients, and the diagnosis of PA can present an important challenge for the clinician."1.33Comparison of confirmatory tests for the diagnosis of primary aldosteronism. ( Fallo, F; Fardella, C; Maccario, M; Marafetti, L; Milan, A; Mosso, L; Mulatero, P; Pizzolo, F; Regolisti, G; Veglio, F, 2006)
"Primary hyperaldosteronism should be considered and screened in all young patients with hypertension."1.33[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore]. ( Li, HZ; Pan, DL; Yan, QZ, 2006)
"Aldosterone has a pivotal role by increasing expression of 11beta-HSD2 in epithelial cells of the colon."1.33Aldosterone enhances 11beta-hydroxysteroid dehydrogenase type 2 expression in colonic epithelial cells in vivo. ( Fukushima, K; Funayama, Y; Haneda, S; Krozowski, ZS; Naito, H; Sasaki, I; Sasano, H; Shibata, C; Suzuki, T; Takahashi, K; Yonezawa, H, 2005)
"Primary aldosteronism is the most common endocrine form of secondary hypertension, but no single test or imaging method always identifies it."1.33The role of adrenal venous sampling in the surgical management of primary aldosteronism. ( Bernante, P; Pelizzo, MR; Rossi, GP; Toniato, A, 2006)
"The prevalence of primary aldosteronism (PA) was assessed in a specialized hypertension center."1.31High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. ( Davoli, S; Negro, A; Perazzoli, F; Regolisti, G; Rossi, E; Sani, C, 2002)
"Primary aldosteronism is a common cause of non-renal secondary hypertension."1.31Normokalemic hyperaldosteronism in patients with resistant hypertension. ( Benchetrit, S; Bernheim, J; Podjarny, E, 2002)
"Although autoimmune sensorineural hearing loss can be effectively treated with corticosteroids, little is known about how these drugs affect cochlear function."1.31Spironolactone blocks glucocorticoid-mediated hearing preservation in autoimmune mice. ( Gross, ND; Kempton, JB; Trune, DR, 2002)
"1."1.31Is primary aldosteronism underdiagnosed in clinical practice? ( Bobrie, G; Fiquet-Kempf, B; Launay-Mignot, P; Plouin, PF, 2001)
"Primary aldosteronism, though an uncommon cause of hypertension, causes significant morbidity, making it important to diagnose and treat this condition."1.30Aldosterone to renin ratios in the evaluation of primary aldosteronism. ( Eng, PH; Fok, AC; Ho, SC; Khoo, DH; Koh, LK; Lim, HS; Lim, SC; Tai, ES; Tan, CE; Tan, KE, 1997)
"In primary hyperaldosteronism, it is important to distinguish between unilateral and bilateral disease, as management strategies differ."1.30Accuracy of CT scanning and adrenal vein sampling in the pre-operative localization of aldosterone-secreting adrenal adenomas. ( Atkinson, AB; Ferrett, CG; Harper, R; McIlrath, EM; McKnight, JA; Russell, CF; Sheridan, B, 1999)
"Primary aldosteronism comprises two different conditions, the tumoral form usually caused by an adenoma and the idiopathic form due to nodular hyperplasia of the two adenals."1.29[Conceptual basis and diagnosis of primary hyperaldosteronism]. ( Amar, J; Begasse, F; Chamontin, B; Guittard, J; Salvador, M, 1995)
"The most common cause of primary aldosteronism is a small aldosterone-secreting adrenal adenoma."1.29CT in the diagnosis of primary aldosteronism: sensitivity in 29 patients. ( Dunnick, NR; Kurylo, L; Leder, RA; Leight, GS; Paulson, E; Roubidoux, MA, 1993)

Research

Studies (166)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (12.05)18.2507
2000's54 (32.53)29.6817
2010's78 (46.99)24.3611
2020's14 (8.43)2.80

Authors

AuthorsStudies
Lin, L1
Zhou, L1
Guo, Y1
Liu, Z2
Chen, T1
Wang, K1
Li, J2
Zhu, Y1
Ren, Y1
Burrello, J3
Buffolo, F2
Domenig, O1
Tetti, M2
Pecori, A1
Monticone, S3
Poglitsch, M2
Mulatero, P6
Lin, C1
Yang, J2
Fuller, PJ2
Jing, H1
Song, Y3
He, W3
Du, Z1
Luo, T2
Cheng, Q3
Yang, S4
Wang, H1
Li, Q4
Hu, J3
Kietsiriroje, N1
Wonghirundecha, R1
Suntornlohanakul, O1
Murray, RD1
Pham, TD1
Verlander, JW1
Wang, Y2
Romero, CA1
Yue, Q1
Chen, C1
Thumova, M1
Eaton, DC1
Lazo-Fernandez, Y1
Wall, SM1
Saida, K1
Kamei, K1
Hamada, R1
Yoshikawa, T1
Kano, Y1
Nagata, H1
Sato, M1
Ogura, M1
Harada, R1
Hataya, H1
Miyazaki, O1
Nosaka, S1
Ito, S2
Ishikura, K1
Fries, CM1
Bae, YJ1
Rayes, N1
Sandner, B1
Isermann, B1
Stumvoll, M1
Fagotto, V1
Reincke, M6
Bidlingmaier, M4
Mandy, V1
Kratzsch, J1
Fenske, WK1
Wada, N1
Miyoshi, A1
Usubuchi, H1
Terae, S1
Shibayama, Y1
Takahashi, B1
Baba, S1
Sugawara, H1
Obara, S1
Saiga, A1
Yokota, H1
Nagano, H1
Sawada, K1
Kubota, Y1
Wada, T1
Horikoshi, T1
Tanaka, T1
Uno, T1
Burrello, A1
Pieroni, J1
Sconfienza, E1
Forestiero, V1
Amongero, M1
Rossato, D2
Veglio, F5
Williams, TA2
Fuss, CT1
Brohm, K1
Kurlbaum, M1
Hannemann, A1
Kendl, S1
Fassnacht, M2
Deutschbein, T2
Hahner, S2
Kroiss, M1
Yozamp, N1
Hundemer, GL2
Moussa, M1
Underhill, J1
Fudim, T1
Sacks, B1
Vaidya, A1
van de Wiel, ECJ1
Küsters, B1
Mann, R1
Veltien, A1
Aalders, TW1
Verhaegh, GW1
Mukai, K2
Deinum, J3
Langenhuijsen, JF1
Hung, A1
Ahmed, S1
Gupta, A1
Davis, A1
Kline, GA5
Leung, AA1
Ruzicka, M2
Hiremath, S1
Rossi, GP4
Crimì, F1
Rossitto, G1
Amar, L2
Azizi, M3
Riester, A2
Degenhart, C3
Widimsky, J1
Naruse, M2
Schultze Kool, L1
Kocjan, T1
Negro, A2
Rossi, E3
Kline, G1
Tanabe, A1
Satoh, F3
Christian Rump, L1
Vonend, O1
Willenberg, HS2
Chee, NYN1
Magill, SB1
Shafigullina, Z1
Quinkler, M2
Oliveras, A1
Cent Wu, V1
Kratka, Z1
Barbiero, G1
Seccia, TM2
Battistel, M1
Starker, LF1
Christakis, I1
Julien, JS1
Schwarz, K1
Graham, P1
Grubbs, EG1
Lee, JE1
Perrier, ND1
Zhang, Y2
Niu, W1
Zheng, F1
Zhang, H1
Zhou, W3
Shen, Z1
Xu, J1
Tang, X1
Zhang, J1
Gao, PJ1
Wang, JG1
Zhu, L1
Ma, L1
Zhen, Q2
Zhang, S3
Mei, M1
Wang, Z2
Qing, H1
Bruemmer, D1
Peng, B1
Higashi, T1
Akaishi, M1
Yokota, M1
Suzuki, T3
Ogawa, S1
Sugiura, Y1
Nishikawa, T2
Nishimoto, K1
Suematsu, M1
Lie, M1
Thorstensen, K1
Guo, Z1
McWhinney, BC1
Ungerer, JPJ1
Ahmed, AH2
Gordon, RD4
Wolley, M1
Stowasser, M4
Wachtel, H1
Bhandari, S1
Roses, RE1
Cohen, DL1
Trerotola, SO1
Fraker, DL1
Kita, T1
Furukoji, E1
Sakae, T1
Kitamura, K1
Xiao, L1
Jiang, Y2
Zhang, C2
Jiang, L2
Su, T2
Ning, G2
Wang, W2
Vivien, M1
Deberles, E1
Morello, R1
Haddouche, A1
Guenet, D1
Reznik, Y2
O'Shea, PM1
Griffin, TP1
Denieffe, S1
Fitzgibbon, MC1
Zhu, KY1
Zhang, WJ1
Li, HY1
Feng, WH1
Zhu, DL1
Li, P1
Kreissl, MC1
Schirbel, A1
Haenscheid, H1
Verburg, FA1
Bock, S1
Saeger, W1
Knoedler, P1
Reiners, C1
Buck, AK1
Allolio, B1
Jansen, PM2
van den Born, BJ1
Frenkel, WJ1
de Bruijne, EL1
Kerstens, MN1
Smulders, YM1
Woittiez, AJ1
Wijbenga, JA1
Zietse, R2
Danser, AH2
van den Meiracker, AH2
Keevil, BG2
Takanami, K1
Kaneta, T1
Morimoto, R2
Nakamura, Y1
Takase, K2
Takahashi, S1
Pasieka, JL4
Harvey, A4
So, B4
Dias, VC4
Fischer, E2
Reiser, MF1
Beuschlein, F3
Glinicki, P1
Jeske, W1
Bednarek-Papierska, L1
Kruszyńska, A1
Gietka-Czernel, M1
Rosłonowska, E1
Słowińska-Srzednicka, J1
Kasperlik-Załuska, A1
Zgliczyński, W1
Ray, JA1
Kushnir, MM1
Palmer, J1
Sadjadi, S1
Rockwood, AL1
Meikle, AW1
Berge, C1
Courand, PY1
Harbaoui, B1
Paget, V1
Khettab, F1
Bricca, G1
Fauvel, JP1
Lantelme, P1
Venos, ES1
Abraham, SB1
Abel, BS1
Sinaii, N1
Saverino, E1
Wade, M1
Nieman, LK1
Zhu, W1
Xie, J1
Luo, Q1
Li, NF1
Yao, XG1
Zhang, DL1
Abulikemu, SF1
Chang, GJ1
Zhou, KM1
Wang, GL1
Wang, MH1
Ouyang, WJ1
Cheng, QY1
Jia, Y1
Lohmeier, TE1
Liu, B1
Hildebrandt, DA1
Cates, AW1
Georgakopoulos, D1
Irwin, ED1
Mailhot, JP1
Traistaru, M1
Soulez, G1
Ladouceur, M1
Giroux, MF1
Gilbert, P1
Zhu, PS1
Bourdeau, I1
Oliva, VL1
Lacroix, A1
Therasse, E1
Lewicka, E1
Dudzińska-Gehrmann, J1
Dąbrowska-Kugacka, A1
Zagożdżon, P1
Stepnowska, E1
Liżewska, A1
Kozłowski, D1
Raczak, G1
Raizman, JE1
Diamandis, EP2
Holmes, D2
Auchus, R1
Cavalier, E1
Leal Reyna, M1
Gómez, RM1
Lupi, SN1
Belli, SH1
Fenili, CA1
Martínez, MS1
Ruibal, GF1
Rossi, MA1
Chervin, RA1
Cornaló, D1
Contreras, LN3
Costa, L1
Nofal, MT1
Damilano, SA1
Pardes, EM1
Manolopoulou, J2
Dietz, A2
Diederich, S1
Junnila, R1
Grimminger, P1
Morganti, A1
Čáp, J1
Gabalec, F1
Li, Y1
Liu, Y1
Wang, X1
Yu, Y1
Abe, T2
Young, WF1
Kobashi, N1
Doi, Y1
Izawa, A1
Akama, K1
Okumura, Y1
Ikenaga, M1
Kimura, H1
Saji, H1
Matsumoto, H1
Long, J1
Feng, Z1
Li, R1
Ren, W1
Zhou, B1
Huby, AC1
Otvos, L1
Belin de Chantemèle, EJ1
Kuipers, AL1
Kammerer, CM1
Pratt, JH1
Bunker, CH1
Wheeler, VW1
Patrick, AL1
Zmuda, JM1
Lucchiari, M1
Rabbia, F2
Mengozzi, G2
Tsiavos, V1
Markou, A1
Papanastasiou, L1
Kounadi, T1
Androulakis, II1
Voulgaris, N1
Zachaki, A1
Kassi, E1
Kaltsas, G1
Chrousos, GP1
Piaditis, GP1
Denimal, D1
Duvillard, L1
Nesterov, V1
Krueger, B1
Bertog, M1
Dahlmann, A1
Palmisano, R1
Korbmacher, C1
Douillard, C1
Houillier, P1
Nussberger, J1
Girerd, X1
Hussein, T1
Mezősi, E1
Bódis, B1
Nemes, O1
Rucz, K1
Bajnok, L1
Zhu, J1
Jin, N1
Zang, L1
Gu, WJ1
Yang, GQ1
Yang, LJ1
Guo, QH1
Wang, XL1
Lyu, ZH1
Ba, JM1
Dou, JT1
Mu, YM1
Tabarin, A1
Nitta, D1
Li, X1
Goswami, R1
Yoshii, Y1
Oki, K1
Gomez-Sanchez, CE4
Ohno, H1
Itcho, K1
Kobuke, K1
Yoneda, M1
Nehme, A1
Cerutti, C1
Zibara, K1
Dennedy, MC1
Annamalai, AK1
Prankerd-Smith, O1
Freeman, N1
Vengopal, K1
Graggaber, J1
Koulouri, O1
Powlson, AS1
Shaw, A1
Halsall, DJ1
Gurnell, M2
Kobayashi, H1
Haketa, A1
Ueno, T1
Ikeda, Y1
Hatanaka, Y1
Tanaka, S1
Otsuka, H1
Abe, M2
Fukuda, N1
Soma, M1
Chatterjee, R1
Davenport, CA1
Svetkey, LP1
Batch, BC1
Lin, PH1
Ramachandran, VS1
Fox, ER1
Harman, J1
Yeh, HC1
Selvin, E1
Correa, A1
Butler, K1
Edelman, D1
Ladurner, R1
Sommerey, S1
Buechner, S1
Hallfeldt, K1
Gallwas, J1
Matsui, H1
Ando, K1
Kawarazaki, H1
Nagae, A1
Fujita, M1
Shimosawa, T1
Nagase, M1
Fujita, T2
Westerdahl, C2
Bergenfelz, A2
Larsson, J1
Nerbrand, C1
Valdemarsson, S2
Wihl, A1
Isaksson, A2
Taylor, PJ2
Cooper, DP1
Weickert, MO1
Schöfl-Siegert, B1
Arafat, AM1
Pfeiffer, AF1
Möhlig, M1
Schöfl, C1
Palumbo, G1
Belfiore, A1
Bernini, G1
Caridi, G1
Desideri, G1
Fabris, B1
Ferri, C1
Giacchetti, G2
Letizia, C1
Maccario, M2
Mallamaci, F1
Mannelli, M1
Patalano, A1
Rizzoni, D1
Pessina, AC2
Mantero, F3
Funder, JW1
Wu, VC1
Kuo, CC1
Chang, HW1
Tsai, CT1
Lin, CY1
Lin, LY1
Lin, YH1
Wang, SM1
Huang, KH1
Fang, CC1
Ho, YL1
Liu, KL1
Chang, CC1
Chueh, SC1
Lin, SL1
Yen, RF1
Wu, KD1
Gomez-Sanchez, EP2
Balaş, M1
Zosin, I1
Maser-Gluth, C1
Hermsen, D1
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Knoefel, WT1
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Zhao, TY1
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Turner, ST1
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Sasano, H2
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Al-Shoumer, KA1
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Marafetti, L1
Cawood, ML1
Kaplan, NM1
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Soeby-Rasmussen, C1
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Dunnick, NR2
Leight, GS1
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Leder, RA1
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van Es, PN1
Schiffers, PM1
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Kazerooni, EA1
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Thornton, SN1
Martial, FP1
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Galaverna, O1
Meile, MJ1
Nicolaïdis, S1
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Nicolet, L1
Grognet, JM1
Ménard, J1
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Khoo, DH1
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Lim, SC1
Koh, LK1
Ho, SC1
Tai, ES1
Fok, AC1
Olson, LJ1
Ho, BY1
Cashdollar, LW1
Drewett, JG1
Deschênes, M1
Dufresne, MP1
Bui, B1
Fenyves, D1
Spahr, L1
Roy, L1
Lafortune, M1
Pomier-Layrargues, G1
Rosenberg Zand, RS1
Jenkins, DJ1
Harper, R1
Ferrett, CG1
McKnight, JA1
McIlrath, EM1
Russell, CF1
Sheridan, B1
Atkinson, AB1
Lopes, HF1
Silva, HB1
Consolim-Colombo, FM1
Barreto Filho, JA1
Riccio, GM1
Giorgi, DM1
Krieger, EM1
Peppercorn, PD1
Allan, C1
Grossman, AB1
Tavintharan, S1
Rajasoorya, C1
Soong, WC1
Dosh, SA1
Mattiasson, I1
Endre, T1
Hulthén, UL1
Schlaich, MP1
Klingbeil, AU1
Jacobi, J1
Delles, C1
Schneider, MP1
Schmidt, BM1
Schmieder, RE1
Benchetrit, S1
Bernheim, J1
Podjarny, E1
Sathyamurthy, I1
Jayanthi, K1
Gross, ND1
Kempton, JB1
Trune, DR1
Fiquet-Kempf, B1
Launay-Mignot, P1
Bobrie, G1
Plouin, PF1
Hambling, C1
Jung, RT1
Gunn, A1
Browning, MC1
Bartlett, WA1
Wambach, G1
Degenhardt, S1
Bönner, G1
Stimpel, M1
Grimm, U1
Krone, W1
Swinkels, LM1
Ross, HA1
Benraad, TJ1

Clinical Trials (19)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
LC-MS/MS-specific Cutoffs for Screening and Confirmatory Testing of Primary Aldosteronism: A Multi-center Study[NCT05959863]300 participants (Anticipated)Observational2023-08-30Recruiting
Multicenter Study on Use and Interpretation of Adrenal Vein Sampling[NCT01234220]2,604 participants (Actual)Observational2010-05-31Completed
Adrenal Function in Critical Illness[NCT00156767]225 participants (Actual)Observational2004-11-12Completed
Case Detection and Confirmation, Subtype Classification of Patients With Primary Aldosteronism[NCT02755519]300 participants (Actual)Observational2014-05-31Completed
Case Detection and Confirmation, Subtype Classification of Patients With Primary Aldosteronism[NCT03500120]200 participants (Actual)Observational2017-09-01Completed
Primary Aldosteronism In Hypertensive Patients in China[NCT03155139]3,500 participants (Actual)Observational2017-06-03Completed
Disparities in CHD in the Jackson Heart Study[NCT00415415]5,302 participants Observational2000-09-30Completed
[NCT00917345]150 participants (Anticipated)Observational2008-01-31Recruiting
A Phase 1 Clinical Trial Evaluating the Safety and Efficacy of up to Two Administrations of the Adrenal PET Tracer [18F]CETO in Healthy Volunteers and Patients With Primary Aldosteronism[NCT04529018]11 participants (Anticipated)Interventional2020-08-03Recruiting
The Impact of Meal Timing on Neurovascular Control in Adults[NCT04133701]34 participants (Actual)Interventional2022-02-02Completed
Identification of New Biomarkers for the Classification and Monitoring of Difficult-to-treat Arterial Hypertension: Prospective Observational Study[NCT03034265]24 participants (Actual)Observational2016-05-31Completed
The Influence of High and Low Salt on Exosomes in the Urine[NCT02823613]10 participants (Actual)Interventional2016-08-31Completed
Genetic Epidemiology of Responses to Antihypertensives[NCT00005520]1,200 participants (Actual)Observational1997-02-28Completed
Prospective Cross-sectional Study on Prevalence of Primary Aldosteronism in Resistant Hypertension and Association With Cardiometabolic Complications[NCT04213963]100 participants (Anticipated)Observational2011-09-01Recruiting
The Prevalence and the Prognosis of Resistant Hypertension Ascertained With Systemic Investigation and Optimal Treatment With Antihypertensive Drugs[NCT01703780]9,638 participants (Actual)Observational2012-07-31Active, not recruiting
Aldosterone-Renin Ratio to Diagnose Primary Aldosteronism in a Population of Patients With Therapy-Resistant Hypertension: Test Characteristics, Diagnostic Value and Predictive Value for Antihypertensive Treatment. The Dutch ARRAT Study.[NCT00407784]500 participants Observational2007-01-31Recruiting
Comparison of Saline Infusion Test, Captopril Challenge Test, and Oral Sodium Loading Test in the Diagnosis of Primary Aldosteronism[NCT04193137]200 participants (Actual)Observational2019-11-30Completed
Prospective Evaluation of Confirmatory Testing For Primary Aldosteronism[NCT04422756]200 participants (Anticipated)Observational2017-01-15Recruiting
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987]122 participants (Actual)Observational2019-07-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for aldosterone and Sensitivity and Specificity

ArticleYear
Performance of the Aldosterone to Renin Ratio as a Screening Test for Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2021, 07-13, Volume: 106, Issue:8

    Topics: Aldosterone; Clinical Decision-Making; Female; Humans; Hyperaldosteronism; Male; Renin; Sensitivity

2021
The aldosterone to renin ratio in the diagnosis of primary aldosteronism: Promises and challenges.
    International journal of clinical practice, 2019, Volume: 73, Issue:7

    Topics: Aldosterone; Biomarkers; Humans; Hyperaldosteronism; Hypertension; Practice Guidelines as Topic; Ren

2019
Novel liquid chromatography tandem mass spectrometry (LC-MS/MS) methods for measuring steroids.
    Best practice & research. Clinical endocrinology & metabolism, 2013, Volume: 27, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Chromatography, Liquid; Humans; Hydrocortisone; Liquid-Liquid

2013
[Adrenal incidentaloma].
    Vnitrni lekarstvi, 2015, Volume: 61, Issue:10

    Topics: Adrenal Gland Neoplasms; Aldosterone; Catecholamines; Diagnosis, Differential; Diagnostic Imaging; H

2015
Aldosterone/direct renin concentration ratio as a screening test for primary aldosteronism: A meta-analysis.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2016, Volume: 17, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Mass Screening; Publication Bias;

2016
Aldosterone and CKD in metabolic syndrome.
    Current hypertension reports, 2008, Volume: 10, Issue:6

    Topics: Albuminuria; Aldosterone; Biomarkers; Female; Humans; Kidney Failure, Chronic; Male; Metabolic Syndr

2008
Aldosterone, sodium, and hypertension: lessons from torcetrapib?
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Aldosterone; Animals; Anticholesteremic Agents; Cholesterol Ester Transfer Proteins; Humans; Hyperch

2010
Factors affecting the aldosterone/renin ratio.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2012, Volume: 44, Issue:3

    Topics: Aldosterone; Diagnostic Tests, Routine; Female; Humans; Hyperaldosteronism; Male; Pregnancy; Renin;

2012
Primary aldosteronism: a common and important problem. A practical guide to the diagnosis and treatment.
    Endokrynologia Polska, 2012, Volume: 63, Issue:4

    Topics: Academic Medical Centers; Aldosterone; Diagnostic Techniques, Endocrine; Diagnostic Tests, Routine;

2012
Plasma renin and aldosterone measurements in low renin hypertensive states.
    Trends in endocrinology and metabolism: TEM, 2005, Volume: 16, Issue:3

    Topics: Aldosterone; Blood Chemical Analysis; Humans; Hypertension; Renin; Sensitivity and Specificity

2005
Optimal use and interpretation of the aldosterone renin ratio to detect aldosterone excess in hypertension.
    Journal of human hypertension, 2006, Volume: 20, Issue:7

    Topics: Aldosterone; Antihypertensive Agents; Captopril; Humans; Hyperaldosteronism; Hypertension; Renin; Se

2006
Measurement of aldosterone in blood.
    Methods in molecular biology (Clifton, N.J.), 2006, Volume: 324

    Topics: Aldosterone; Animals; Humans; Radioimmunoassay; Sensitivity and Specificity

2006
[Screening tests and diagnostic examinations of hypertensives for primary aldosteronism].
    Rinsho byori. The Japanese journal of clinical pathology, 2006, Volume: 54, Issue:11

    Topics: Adrenal Cortex Function Tests; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Antihyperten

2006
The diagnosis of essential and secondary hypertension in adults.
    The Journal of family practice, 2001, Volume: 50, Issue:8

    Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Algorithms; Angiography; Blood Pressure Determination;

2001
Aldosterone antagonists - revisited.
    The Journal of the Association of Physicians of India, 2001, Volume: 49

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Female; Heart Failure; Humans; Male; Mineralo

2001

Trials

13 trials available for aldosterone and Sensitivity and Specificity

ArticleYear
A combination of captopril challenge test after saline infusion test improves diagnostic accuracy for primary aldosteronism.
    Clinical endocrinology, 2020, Volume: 92, Issue:2

    Topics: Adrenal Cortex Function Tests; Adult; Aldosterone; Captopril; Diagnosis, Differential; Drug Administ

2020
A reverse postural test as a screening tool for aldosterone-producing adenoma: a pilot study.
    Endocrine, 2009, Volume: 36, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Diagnosis, Differential; Exercise; Female; Hum

2009
Diagnosis of primary aldosteronism: comparison of post-captopril active renin concentration and plasma renin activity.
    Clinica chimica acta; international journal of clinical chemistry, 2010, May-02, Volume: 411, Issue:9-10

    Topics: Adult; Aged; Aldosterone; Area Under Curve; Captopril; Diagnosis, Differential; Female; Humans; Hype

2010
Captopril suppression: limitations for confirmation of primary aldosteronism.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2011, Volume: 12, Issue:3

    Topics: Adult; Aldosterone; Antihypertensive Agents; Captopril; Female; Health; Humans; Hyperaldosteronism;

2011
Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:1

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Carbon Radioisotopes; Etomidat

2012
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Hyperaldosteronism among black and white subjects with resistant hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug

2002
Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:6

    Topics: Aldosterone; Amlodipine; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Confounding Factors,

2002
Aldosterone induces contraction of the resistance arteries in man.
    Atherosclerosis, 2003, Volume: 166, Issue:2

    Topics: Adult; Aldosterone; Blood Pressure Determination; Cross-Over Studies; Dose-Response Relationship, Dr

2003
Comparison of active renin concentration and plasma renin activity for the diagnosis of primary hyperaldosteronism in patients with an adrenal mass.
    European journal of endocrinology, 2004, Volume: 150, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Calibration; Female; Humans; Hyperaldost

2004
Use of steroid profiles in determining the cause of adrenal insufficiency.
    Steroids, 2007, Volume: 72, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Chr

2007
Imaging of aldosterone-secreting adenomas: a prospective comparison of computed tomography and magnetic resonance imaging in 27 patients with suspected primary aldosteronism.
    Journal of human hypertension, 1993, Volume: 7, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Dexamethasone; Female; H

1993
'Captopril test', with blood pressure and peripheral renin as response variables in hypertensive patients with suspected renal artery stenosis.
    Journal of human hypertension, 1995, Volume: 9, Issue:9

    Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure Determination; Ca

1995
Captopril suppression tests in normotensive individuals.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2000, Volume: 83, Issue:3

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure Determination; Captopri

2000

Other Studies

138 other studies available for aldosterone and Sensitivity and Specificity

ArticleYear
Can incomplete adrenal venous sampling data be used in predicting the subtype of primary aldosteronism?
    Annales d'endocrinologie, 2019, Volume: 80, Issue:5-6

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Specimen Collection; China; Clinical Decision-Making; Fema

2019
Renin-Angiotensin-Aldosterone System Triple-A Analysis for the Screening of Primary Aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:1

    Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Essential Hypertension; Female; Humans; Hyperaldo

2020
Construction of a predictive scoring system as a guide to screening and confirmation of the diagnosis of primary aldosteronism.
    Clinical endocrinology, 2020, Volume: 92, Issue:3

    Topics: Adolescent; Adult; Aged; Aldosterone; Cross-Sectional Studies; Diagnostic Techniques, Endocrine; Fem

2020
Aldosterone Regulates Pendrin and Epithelial Sodium Channel Activity through Intercalated Cell Mineralocorticoid Receptor-Dependent and -Independent Mechanisms over a Wide Range in Serum Potassium.
    Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Anion Transport Proteins; Cells, Cultured; Chloride-Bicarbonat

2020
A simple, refined approach to diagnosing renovascular hypertension in children: A 10-year study.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:8

    Topics: Aldosterone; Catheterization; Child; Child, Preschool; Computed Tomography Angiography; Female; Huma

2020
Prospective evaluation of aldosterone LC-MS/MS-specific cutoffs for the saline infusion test.
    European journal of endocrinology, 2020, Volume: 183, Issue:2

    Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chrom

2020
Prediction of unilateral hyperaldosteronism on adrenal vein sampling using captopril challenge test in patients with primary aldosteronism.
    Endocrine journal, 2021, Jan-28, Volume: 68, Issue:1

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Specimen Collection; Captopril; Diagnosis, Differential; D

2021
131I-6β-iodomethyl-19-norcholesterol adrenal scintigraphy as an alternative to adrenal venous sampling in differentiating aldosterone-producing adenoma from bilateral idiopathic hyperaldosteronism.
    Nuclear medicine communications, 2020, Volume: 41, Issue:12

    Topics: 19-Iodocholesterol; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Diagnosis,

2020
Prediction of hyperaldosteronism subtypes when adrenal vein sampling is unilaterally successful.
    European journal of endocrinology, 2020, Volume: 183, Issue:6

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Specimen Collection; Diagnosis, Differential; Female; Huma

2020
Confirmatory testing of primary aldosteronism with saline infusion test and LC-MS/MS.
    European journal of endocrinology, 2021, Volume: 184, Issue:1

    Topics: Adult; Aged; Aldosterone; Blood Chemical Analysis; Chromatography, Liquid; Cohort Studies; Diagnosis

2021
Intraindividual Variability of Aldosterone Concentrations in Primary Aldosteronism: Implications for Case Detection.
    Hypertension (Dallas, Tex. : 1979), 2021, 03-03, Volume: 77, Issue:3

    Topics: Adult; Aldosterone; Biological Variation, Individual; Chromatography, Liquid; Female; Humans; Hypera

2021
Partial Adrenalectomy Carries a Considerable Risk of Incomplete Cure in Primary Aldosteronism.
    The Journal of urology, 2021, Volume: 206, Issue:2

    Topics: Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Endosonography; Female; Genotype; Humans; Hypera

2021
Identification of Surgically Curable Primary Aldosteronism by Imaging in a Large, Multiethnic International Study.
    The Journal of clinical endocrinology and metabolism, 2021, 10-21, Volume: 106, Issue:11

    Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Asia; Australia; Cohort Studies; Europe; Female;

2021
Considering Postoperative Functional Hypoaldosteronism after Unilateral Adrenalectomy.
    The American surgeon, 2017, Jun-01, Volume: 83, Issue:6

    Topics: Adrenalectomy; Adult; Aldosterone; Biomarkers; Female; Follow-Up Studies; Humans; Hyperaldosteronism

2017
Identifying unilateral disease in Chinese patients with primary aldosteronism by using a modified prediction score.
    Journal of hypertension, 2017, Volume: 35, Issue:12

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hyperaldostero

2017
Confirmatory Tests for the Diagnosis of Primary Aldosteronism: A Prospective Diagnostic Accuracy Study.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Adult; Aldosterone; Captopril; Clinical Chemistry Tes

2018
A method for determination of aldosterone in adrenal tributary venous serum by derivatization using Girard P reagent isotopologues followed by LC/ESI-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Aug-15, Volume: 1092

    Topics: Adrenal Glands; Aldosterone; Chromatography, Liquid; Humans; Indicators and Reagents; Isotopes; Line

2018
A precise, sensitive and stable LC-MSMS method for detection of picomolar levels of serum aldosterone.
    Scandinavian journal of clinical and laboratory investigation, 2018, Volume: 78, Issue:5

    Topics: Aldosterone; Biomarkers; Chromatography, Liquid; Humans; Hyperaldosteronism; Liquid-Liquid Extractio

2018
Aldosterone LC-MS/MS Assay-Specific Threshold Values in Screening and Confirmatory Testing for Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2018, 11-01, Volume: 103, Issue:11

    Topics: Adult; Aged; Aldosterone; Chromatography, High Pressure Liquid; Diagnostic Techniques, Endocrine; Fe

2018
Primary aldosteronism with nonlocalizing imaging.
    Surgery, 2019, Volume: 165, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Aldosterone; Female; Humans; Hydroc

2019
Efficient screening of patients with aldosterone-producing adenoma using the ACTH stimulation test.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2019, Volume: 42, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Captopril;

2019
A novel clinical nomogram to predict bilateral hyperaldosteronism in Chinese patients with primary aldosteronism.
    Clinical endocrinology, 2019, Volume: 90, Issue:6

    Topics: Adult; Aldosterone; Algorithms; Calibration; China; Endocrinology; Female; Humans; Hyperaldosteronis

2019
Evaluation of Biochemical Conditions Allowing Bypass of Confirmatory Testing in The Workup of Primary Aldosteronism: A Retrospective Study in a French Hypertensive Population.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2019, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperte

2019
The captopril challenge test for diagnosing primary Aldosteronism in a Chinese population.
    BMC endocrine disorders, 2019, Jun-24, Volume: 19, Issue:1

    Topics: Adult; Aldosterone; Captopril; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged;

2019
[¹²³I]Iodometomidate imaging in adrenocortical carcinoma.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:7

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aldosterone; Cohort

2013
Test characteristics of the aldosterone-to-renin ratio as a screening test for primary aldosteronism.
    Journal of hypertension, 2014, Volume: 32, Issue:1

    Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Renin; Reproducibility of

2014
Characterization of lipid-rich adrenal tumors by FDG PET/CT: Are they hormone-secreting or not?
    Annals of nuclear medicine, 2014, Volume: 28, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Cortisone; Female; Fluorodeoxyglucose F1

2014
A marked proportional rise in IVC aldosterone following cosyntropin administration during AVS is a signal to the presence of adrenal hyperplasia in primary aldosteronism.
    Journal of human hypertension, 2014, Volume: 28, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Adult; Aldosterone;

2014
Age below 40 or a recently proposed clinical prediction score cannot bypass adrenal venous sampling in primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:6

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Specimen Collection; Female; Germany; Humans; Hyperaldoste

2014
High-probability features of primary aldosteronism may obviate the need for confirmatory testing without increasing false-positive diagnoses.
    Journal of clinical hypertension (Greenwich, Conn.), 2014, Volume: 16, Issue:7

    Topics: Adrenal Glands; Adult; Aldosterone; False Positive Reactions; Female; Humans; Hydrocortisone; Hypera

2014
Despite limited specificity, computed tomography predicts lateralization and clinical outcome in primary aldosteronism.
    World journal of surgery, 2014, Volume: 38, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Age Factors; Aldosterone; Blood Pressure; F

2014
The ratios of aldosterone / plasma renin activity (ARR) versus aldosterone / direct renin concentration (ADRR).
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:4

    Topics: Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Renin; Sensitivity

2015
Enhancement of specificity of aldosterone measurement in human serum and plasma using 2D-LC-MS/MS and comparison with commercial immunoassays.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Nov-01, Volume: 970

    Topics: Aldosterone; Chromatography, Liquid; Humans; Immunoassay; Linear Models; Liquid-Liquid Extraction; R

2014
Decreased plasma prorenin levels in primary aldosteronism: potential diagnostic implications.
    Journal of hypertension, 2015, Volume: 33, Issue:1

    Topics: Adenoma; Adult; Aldosterone; Cohort Studies; Essential Hypertension; Female; Humans; Hyperaldosteron

2015
A clinical prediction score for diagnosing unilateral primary aldosteronism may not be generalizable.
    BMC endocrine disorders, 2014, Dec-11, Volume: 14

    Topics: Adrenal Glands; Adult; Aldosterone; Cosyntropin; Female; Glomerular Filtration Rate; Humans; Hydroco

2014
Primary vs secondary adrenal insufficiency: ACTH-stimulated aldosterone diagnostic cut-off values by tandem mass spectrometry.
    Clinical endocrinology, 2015, Volume: 83, Issue:3

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Cosyntropin; Cross-Sectional

2015
Diagnostic value of ACTH stimulation test in determining the subtypes of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:5

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotro

2015
Potential effects of age on screening for primary aldosteronism.
    Journal of human hypertension, 2016, Volume: 30, Issue:1

    Topics: Adult; Age Factors; Aged; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Male; Middle

2016
Global- and renal-specific sympathoinhibition in aldosterone hypertension.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:6

    Topics: Aldosterone; Analysis of Variance; Animals; Baroreflex; Blood Pressure; Disease Models, Animal; Dogs

2015
Adrenal Vein Sampling in Primary Aldosteronism: Sensitivity and Specificity of Basal Adrenal Vein to Peripheral Vein Cortisol and Aldosterone Ratios to Confirm Catheterization of the Adrenal Vein.
    Radiology, 2015, Volume: 277, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Catheterization, Peripheral; Female; Human

2015
Plasma biomarkers as predictors of recurrence of atrial fibrillation.
    Polskie Archiwum Medycyny Wewnetrznej, 2015, Volume: 125, Issue:6

    Topics: Aged; Aged, 80 and over; Aldosterone; Atrial Fibrillation; Atrial Natriuretic Factor; Electric Count

2015
A renin-ssance in primary aldosteronism testing: obstacles and opportunities for screening, diagnosis, and management.
    Clinical chemistry, 2015, Volume: 61, Issue:8

    Topics: Aldosterone; Calcium Channels, L-Type; Fludrocortisone; G Protein-Coupled Inwardly-Rectifying Potass

2015
Screening for primary aldosteronism in an argentinian population: a multicenter prospective study.
    Archives of endocrinology and metabolism, 2015, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Argentina; Female; Humans; Hyperaldosteronism; Hypertension; M

2015
Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays.
    Journal of hypertension, 2015, Volume: 33, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Blood Pressure; Essential Hypertension; Female; Humans;

2015
Sodium Infusion Test for Diagnosis of Primary Aldosteronism in Chinese Population.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:1

    Topics: Adult; Aged; Aldosterone; Area Under Curve; Asian People; Blood Pressure; Female; Humans; Hyperaldos

2016
A Novel CYP11B2-Specific Imaging Agent for Detection of Unilateral Subtypes of Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Animals; Autoradiography; Benzimidazo

2016
[Evaluation of the ratio of plasma aldosterone to rennin concentration measured by an automated chemiluminescent immunoassay in screening for primary aldosteronism].
    Zhonghua nei ke za zhi, 2016, Volume: 55, Issue:1

    Topics: Aldosterone; Area Under Curve; Case-Control Studies; Chymosin; Essential Hypertension; Humans; Hyper

2016
Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Aldosterone; Analysis of Variance; Animals; Cardiovascular Diseases; Disease Models, Animal; Endothe

2016
Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:5

    Topics: Adult; Age Factors; Aged; Aldosterone; Anthropometry; Biomarkers; Black People; Body Mass Index; Bon

2016
Diagnostic accuracy of aldosterone and renin measurement by chemiluminescent immunoassay and radioimmunoassay in primary aldosteronism.
    Journal of hypertension, 2016, Volume: 34, Issue:5

    Topics: Aldosterone; Female; Humans; Hyperaldosteronism; Luminescent Measurements; Male; Middle Aged; Prospe

2016
A new highly sensitive and specific overnight combined screening and diagnostic test for primary aldosteronism.
    European journal of endocrinology, 2016, Volume: 175, Issue:1

    Topics: Adult; Aged; Aldosterone; Captopril; Dexamethasone; Diagnostic Tests, Routine; Female; Humans; Hyper

2016
2016 Endocrine Society guidelines update for the diagnosis of primary aldosteronism: are the proposed aldosterone-to-renin ratio cut-off values relevant in the era of fully automated immunoassays?
    Annals of clinical biochemistry, 2016, Volume: 53, Issue:6

    Topics: Aldosterone; Automation, Laboratory; Endocrinology; Humans; Hyperaldosteronism; Hypertension; Immuno

2016
In Liddle Syndrome, Epithelial Sodium Channel Is Hyperactive Mainly in the Early Part of the Aldosterone-Sensitive Distal Nephron.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:6

    Topics: Aldosterone; Animals; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Kidney Tubul

2016
SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps.
    Annales d'endocrinologie, 2016, Volume: 77, Issue:3

    Topics: Age Factors; Aldosterone; Antihypertensive Agents; Blood Specimen Collection; Female; Humans; Hypera

2016
[Renin and aldosterone determinations in hypertensive patients].
    Orvosi hetilap, 2016, May-22, Volume: 157, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Biomarkers; Female; Humans; Hyperaldosteronism; Hyperte

2016
[An evaluation of plasma aldosterone-to-active-renin ratio in different postures in combination with aldosterone concentration in the diagnosis of aldosteronoma].
    Zhonghua nei ke za zhi, 2016, Volume: 55, Issue:6

    Topics: Aldosterone; Asian People; China; Essential Hypertension; Humans; Hyperaldosteronism; Hypertension;

2016
SFE/SFHTA/AFCE consensus on primary aldosteronism, part 3: Confirmatory testing.
    Annales d'endocrinologie, 2016, Volume: 77, Issue:3

    Topics: Aldosterone; Captopril; Diagnosis, Differential; France; Humans; Hyperaldosteronism; Renin; Sensitiv

2016
Predictors for Tolvaptan Treatment and Future Perspectives.
    International heart journal, 2016, Jul-27, Volume: 57, Issue:4

    Topics: Aldosterone; Antidiuretic Hormone Receptor Antagonists; Arginine; Benzazepines; Biomarkers; Diuresis

2016
Hypomethylation of CYP11B2 in Aldosterone-Producing Adenoma.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:6

    Topics: Adrenocortical Adenoma; Aldosterone; DNA Methylation; Female; G Protein-Coupled Inwardly-Rectifying

2016
Transcriptomic Analysis Reveals Novel Transcription Factors Associated With Renin-Angiotensin-Aldosterone System in Human Atheroma.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:6

    Topics: Aldosterone; Animals; Carotid Arteries; Carotid Artery Diseases; Cluster Analysis; Gene Expression P

2016
Low DHEAS: A Sensitive and Specific Test for the Detection of Subclinical Hypercortisolism in Adrenal Incidentalomas.
    The Journal of clinical endocrinology and metabolism, 2017, Mar-01, Volume: 102, Issue:3

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Ad

2017
Scoring system for the diagnosis of bilateral primary aldosteronism in the outpatient setting before adrenal venous sampling.
    Clinical endocrinology, 2017, Volume: 86, Issue:4

    Topics: Adrenal Glands; Adult; Aldosterone; Blood Specimen Collection; Diagnosis, Differential; Female; Huma

2017
Serum potassium is a predictor of incident diabetes in African Americans with normal aldosterone: the Jackson Heart Study.
    The American journal of clinical nutrition, 2017, Volume: 105, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Black or African American; Diabetes Mellitus, Type 2; F

2017
Accuracy of adrenal imaging and adrenal venous sampling in diagnosing unilateral primary aldosteronism.
    European journal of clinical investigation, 2017, Volume: 47, Issue:5

    Topics: Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged

2017
Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:2

    Topics: Aldosterone; Animals; Blood Pressure Determination; Disease Models, Animal; Echocardiography, Dopple

2008
Re-evaluation of the fludrocortisone test: duration, NaCl supplementation and cut-off limits for aldosterone.
    Scandinavian journal of clinical and laboratory investigation, 2009, Volume: 69, Issue:2

    Topics: Adult; Aldosterone; Female; Fludrocortisone; Humans; Hyperaldosteronism; Male; Middle Aged; Potassiu

2009
Measurement of aldosterone in human plasma by semiautomated HPLC-tandem mass spectrometry.
    Clinical chemistry, 2009, Volume: 55, Issue:6

    Topics: Adolescent; Adult; Aged; Aldosterone; Automation; Chromatography, High Pressure Liquid; Cohort Studi

2009
Within-patient reproducibility of the aldosterone: renin ratio in primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldoste

2010
Aldosterone-producing adenomas: mining for genes.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:6

    Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Female; Genetic Predisposition to Disease; Genetic T

2010
Indicators of mineralocorticoid excess in the evaluation of primary aldosteronism.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2010, Volume: 33, Issue:8

    Topics: Adult; Aged; Aldosterone; Biomarkers; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi

2010
[The accuracy of combining aldosterone to renin ratio and low renin level in diagnosing primary aldosteronism].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:3

    Topics: Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; ROC C

2010
The management of aldosterone-producing adrenal adenomas--does adrenalectomy increase costs?
    Surgery, 2010, Volume: 148, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aged; Aldosterone; Algorithms; Costs and Cost Analy

2010
Prognostic value of plasma renin activity in heart failure.
    The American journal of cardiology, 2011, Jul-15, Volume: 108, Issue:2

    Topics: Aged; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bioma

2011
Aldosterone stimulates the cardiac Na(+)/H(+) exchanger via transactivation of the epidermal growth factor receptor.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:5

    Topics: Aldosterone; Animals; Cells, Cultured; ErbB Receptors; Models, Animal; Myocytes, Cardiac; Phosphoryl

2011
Effect of age on aldosterone/renin ratio (ARR) and comparison of screening accuracy of ARR plus elevated serum aldosterone concentration for primary aldosteronism screening in different age groups.
    Endocrine, 2012, Volume: 42, Issue:1

    Topics: Adult; Age Factors; Aged; Aging; Aldosterone; Case-Control Studies; Female; Humans; Hyperaldosteroni

2012
Determination of serum aldosterone by liquid chromatography and tandem mass spectrometry: a liquid-liquid extraction method for the ABSCIEX API-5000 mass spectrometry system.
    Journal of clinical pathology, 2012, Volume: 65, Issue:5

    Topics: Aldosterone; Calibration; Chromatography, High Pressure Liquid; Humans; Hyperaldosteronism; Liquid-L

2012
The circadian clock modulates renal sodium handling.
    Journal of the American Society of Nephrology : JASN, 2012, Volume: 23, Issue:6

    Topics: Aldosterone; Animals; Circadian Clocks; CLOCK Proteins; Disease Models, Animal; Homeostasis; Hydroxy

2012
Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Adipocytes; Aldosterone; Animals; Benzimidazoles; Biphenyl Compounds; Calcineurin; Cells, Cultured;

2012
TASK-3 channel deletion in mice recapitulates low-renin essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Hy

2012
One-hour upright posture is an ideal position for serum aldosterone concentration and plasma renin activity measuring on primary aldosteronism screening.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:7

    Topics: Adult; Aldosterone; China; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension

2012
Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:8

    Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Chromogranin A; Diagnosis, Diff

2012
The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Aldosterone; Animals; Biomarkers; Diet, Sodium-Restricted; Disease Models, Animal; Dose-Response Rel

2012
The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Aldosterone; Animals; Biomarkers; Diet, Sodium-Restricted; Disease Models, Animal; Dose-Response Rel

2012
The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Aldosterone; Animals; Biomarkers; Diet, Sodium-Restricted; Disease Models, Animal; Dose-Response Rel

2012
The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Aldosterone; Animals; Biomarkers; Diet, Sodium-Restricted; Disease Models, Animal; Dose-Response Rel

2012
Quantitation of aldosterone in human plasma by ultra high performance liquid chromatography tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jan-15, Volume: 913-914

    Topics: Aldosterone; Chromatography, High Pressure Liquid; Humans; Hyperaldosteronism; Linear Models; Reprod

2013
Regulation of the renin-angiotensin-aldosterone system in fibromyalgia.
    The Journal of rheumatology, 2002, Volume: 29, Issue:7

    Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure Determination; Case-Control Studies;

2002
High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives.
    American journal of hypertension, 2002, Volume: 15, Issue:10 Pt 1

    Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Hyperaldost

2002
Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.
    Clinical chemistry, 2002, Volume: 48, Issue:11

    Topics: Adult; Aldosterone; Black People; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age

2002
[Conn syndrome as cause of stubborn hypertension. Which hypertensives should you screen?].
    MMW Fortschritte der Medizin, 2003, Feb-27, Volume: 145, Issue:9

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic beta-Antagonists; Aldosterone; Angiotens

2003
Urinary tetrahydroaldosterone as a screening method for primary aldosteronism: a comparative study.
    American journal of hypertension, 2003, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Aldosterone; Female; Glucuronides; Humans; Hyperaldosteronism; Male; Mass Screeni

2003
Impaired 11-beta hydroxysteroid dehydrogenase type 2 activity in sweat gland ducts in human essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenal Cortex Hormones; Adult; Aldosterone; Bicarbonat

2004
Diagnosis of primary aldosteronism: value of different screening parameters and influence of antihypertensive medication.
    European journal of endocrinology, 2004, Volume: 150, Issue:3

    Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertensi

2004
Looking at non-genomic vascular effects of aldosterone.
    Atherosclerosis, 2004, Volume: 173, Issue:1

    Topics: Aldosterone; Endothelins; Forearm; Genome, Human; Humans; Regional Blood Flow; Renin-Angiotensin Sys

2004
Diagnostic performance of CT versus MR in detecting aldosterone-producing adenoma in primary hyperaldosteronism (Conn's syndrome).
    European radiology, 2004, Volume: 14, Issue:10

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Female; Humans; Hyperaldostero

2004
A new less-invasive and more informative low-dose ACTH test: salivary steroids in response to intramuscular corticotrophin.
    Clinical endocrinology, 2004, Volume: 61, Issue:6

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aldosterone; Case-Control Studies; Drug A

2004
Aldosterone enhances 11beta-hydroxysteroid dehydrogenase type 2 expression in colonic epithelial cells in vivo.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:7

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Base Sequence; Biopsy, Needle; Bl

2005
Comparison of adrenal vein sampling value between aldosterone producing adrenal adenoma and non-functioning adrenal adenoma: evaluation using receiver operating characteristic analysis.
    Acta radiologica (Stockholm, Sweden : 1987), 2005, Volume: 46, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; False Positive Reactions; Female; Fun

2005
Screening for primary aldosteronism: progress and frustration.
    Journal of hypertension, 2006, Volume: 24, Issue:4

    Topics: Aldosterone; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Mass Screening; Sensitivity and

2006
Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism: need for a standardized protocol.
    Journal of hypertension, 2006, Volume: 24, Issue:4

    Topics: Aldosterone; Diagnostic Tests, Routine; Female; Humans; Hyperaldosteronism; Male; Mass Screening; Mi

2006
The role of adrenal venous sampling in the surgical management of primary aldosteronism.
    World journal of surgery, 2006, Volume: 30, Issue:4

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hype

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Comparison of confirmatory tests for the diagnosis of primary aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:7

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Fludrocortisone; Humans; Hyper

2006
Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism.
    Journal of hypertension, 2006, Volume: 24, Issue:9

    Topics: Aldosterone; Chemistry, Clinical; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Mass Screen

2006
Raised plasma aldosterone and natriuretic peptides in atrial fibrillation.
    Cardiology, 2007, Volume: 108, Issue:1

    Topics: Adult; Aged; Aldosterone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Cohort Studies; C

2007
[Causes of delaying diagnosis of primary hyperaldosteronism with adrenal adenoma and strategy therefore].
    Zhonghua yi xue za zhi, 2006, Nov-14, Volume: 86, Issue:42

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers, Tumor; Chymo

2006
Morning plasma aldosterone predicts the subtype of primary aldosteronism independent of sodium intake.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2007, Volume: 29, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Biomarkers; Circadian Rh

2007
Both estrogen receptor subtypes, alpha and beta, attenuate cardiovascular remodeling in aldosterone salt-treated rats.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:2

    Topics: Aldosterone; Analysis of Variance; Animals; Cardiovascular Physiological Phenomena; Disease Models,

2007
Captopril test can give misleading results in patients with suspect primary aldosteronism.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:2

    Topics: Aldosterone; Captopril; Clinical Laboratory Techniques; Cohort Studies; Female; Humans; Hyperaldoste

2007
Adjunctive use of C-arm CT may eliminate technical failure in adrenal vein sampling.
    Journal of vascular and interventional radiology : JVIR, 2007, Volume: 18, Issue:9

    Topics: Adrenal Glands; Aldosterone; Blood Chemical Analysis; Catheterization, Peripheral; Diagnostic Errors

2007
Separation of corticosteroids by microemulsion EKC with diethyl L-tartrate as the oil phase.
    Electrophoresis, 2007, Volume: 28, Issue:20

    Topics: Adrenal Cortex Hormones; Aldosterone; Buffers; Chromatography, Micellar Electrokinetic Capillary; Co

2007
Diagnostic value of salivary cortisol in end stage renal disease.
    Steroids, 2008, Volume: 73, Issue:1

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Biomarkers; Humans; Hydrocortisone;

2008
The aldosterone to renin ratio in the evaluation of patients with incidentally detected adrenal masses.
    Endocrine, 2007, Volume: 32, Issue:2

    Topics: Adrenal Gland Diseases; Aldosterone; Biomarkers; Case-Control Studies; Diagnosis, Differential; Fema

2007
Determination of aldosterone in serum by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Feb-01, Volume: 862, Issue:1-2

    Topics: Aldosterone; Calibration; Chromatography, Liquid; Humans; Radioimmunoassay; Reference Standards; Rep

2008
Localization of aldosterone-producing adrenocortical adenomas: significance of adrenal venous sampling.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:11

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Blood Spec

2007
A highly sensitive immunofluorometric assay for the measurement of aldosterone in small sample volumes: validation in mouse serum.
    The Journal of endocrinology, 2008, Volume: 196, Issue:2

    Topics: Aging; Aldosterone; Animals; Chromatography; Dose-Response Relationship, Drug; Female; Fluorescence;

2008
Diagnostic accuracy of adrenal venous sampling in comparison with other parameters in primary aldosteronism.
    Endocrine journal, 2008, Volume: 55, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Age Factors; Aldosterone; Female; Humans; Hydroc

2008
[Conceptual basis and diagnosis of primary hyperaldosteronism].
    Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyper

1995
Combined fractional excretion of sodium and urea better predicts response to saline in hyponatremia than do usual clinical and biochemical parameters.
    The American journal of medicine, 1995, Volume: 99, Issue:4

    Topics: Aged; Aged, 80 and over; Aldosterone; Creatinine; Diuretics; Drinking Behavior; Extracellular Space;

1995
Cortisol is transported by the multidrug resistance gene product P-glycoprotein.
    British journal of cancer, 1993, Volume: 67, Issue:2

    Topics: Adrenal Glands; Aldosterone; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biolo

1993
Solid phase radioimmunoassay for the determination of aldosterone excretion.
    Journal of immunoassay, 1993, Volume: 14, Issue:4

    Topics: Aldosterone; Animals; Antibody Specificity; Chromatography, Paper; Glucuronates; Humans; Immune Sera

1993
The diagnosis of primary aldosteronism and separation of two major subtypes.
    Archives of internal medicine, 1993, Sep-27, Volume: 153, Issue:18

    Topics: Adult; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Middle Aged; Renin; Sensiti

1993
CT in the diagnosis of primary aldosteronism: sensitivity in 29 patients.
    AJR. American journal of roentgenology, 1993, Volume: 160, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Female; Humans; Hyperald

1993
Hyperaldosteronism: sampling the adrenal veins.
    Radiology, 1996, Volume: 198, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Aldos

1996
Differentiation of adrenal adenomas from nonadenomas using CT attenuation values.
    AJR. American journal of roentgenology, 1996, Volume: 166, Issue:3

    Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aged; Age

1996
Effects of DOCA pretreatment on neuronal sensitivity and cell responsiveness to angiotensin II, in the bed nucleus of the stria terminalis in the rat.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Desoxyco

1996
High plasma level of N-acetyl-seryl-aspartyl-lysyl-proline: a new marker of chronic angiotensin-converting enzyme inhibition.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Biomar

1997
Aldosterone to renin ratios in the evaluation of primary aldosteronism.
    Annals of the Academy of Medicine, Singapore, 1997, Volume: 26, Issue:6

    Topics: Adrenocortical Adenoma; Adult; Aged; Aldosterone; Humans; Hyperaldosteronism; Middle Aged; Renin; Re

1997
Functionally active catalytic domain is essential for guanylyl cyclase-linked receptor mediated inhibition of human aldosterone synthesis.
    Molecular pharmacology, 1998, Volume: 54, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Bacterial Toxins; Binding Sites; Cells, Cultured; COS Cells; C

1998
Predictors of clinical response to transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients with refractory ascites.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aldosterone; Ascites; Creatinine; Female; Follow-Up Studies; Humans;

1999
Development and evaluation of a competitive time-resolved immunofluorometric assay for the estrogen-regulated protein pS2.
    Journal of clinical laboratory analysis, 1999, Volume: 13, Issue:5

    Topics: Aldosterone; Amino Acid Sequence; Antibodies, Monoclonal; Binding, Competitive; Biotin; Breast Neopl

1999
Accuracy of CT scanning and adrenal vein sampling in the pre-operative localization of aldosterone-secreting adrenal adenomas.
    QJM : monthly journal of the Association of Physicians, 1999, Volume: 92, Issue:11

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Biomarkers, Tumor; Female; Humans; Hydrocortis

1999
Autonomic abnormalities demonstrable in young normotensive subjects who are children of hypertensive parents.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2000, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Aldosterone; Baroreflex; Blood Pressure; Body Mass Index; Chi-Square Distribution

2000
Primary hyperaldosteronism (Conn syndrome): MR imaging findings.
    Radiology, 2000, Volume: 214, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Female; Huma

2000
Insulin sensitivity with respect to glucose metabolism in hypertension-prone men did not predict the blood pressure increase in 5 years.
    Journal of human hypertension, 2001, Volume: 15, Issue:11

    Topics: Adult; Aldosterone; Blood Glucose; Blood Pressure; Body Mass Index; Family Health; Follow-Up Studies

2001
Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension.
    Journal of hypertension, 2002, Volume: 20, Issue:1

    Topics: Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Family Health; Germany; Hemody

2002
Normokalemic hyperaldosteronism in patients with resistant hypertension.
    The Israel Medical Association journal : IMAJ, 2002, Volume: 4, Issue:1

    Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Creatinine; Female; Humans;

2002
Spironolactone blocks glucocorticoid-mediated hearing preservation in autoimmune mice.
    The Laryngoscope, 2002, Volume: 112, Issue:2

    Topics: Aldosterone; Animals; Audiometry, Pure-Tone; Auditory Threshold; Disease Models, Animal; Drug Intera

2002
Is primary aldosteronism underdiagnosed in clinical practice?
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:12

    Topics: Adrenal Glands; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Humans; Hyperaldostero

2001
Re-evaluation of the captopril test for the diagnosis of primary hyperaldosteronism.
    Clinical endocrinology, 1992, Volume: 36, Issue:5

    Topics: Adult; Aged; Aldosterone; Captopril; Evaluation Studies as Topic; Female; Humans; Hyperaldosteronism

1992
[Does the captopril test improve the diagnosis of primary hyperaldosteronism?].
    Deutsche medizinische Wochenschrift (1946), 1992, Jul-31, Volume: 117, Issue:31-32

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Pressure; Captopril; Diagnosis, Differen

1992
Scintillation proximity assay: determination of steroid hormones without separation of antibody-bound and free ligand.
    Annals of clinical biochemistry, 1991, Volume: 28 ( Pt 1)

    Topics: Aldosterone; Antibodies; Humans; Hydrocortisone; Ligands; Radioimmunoassay; Reproducibility of Resul

1991