Page last updated: 2024-12-09
propylenethiourea
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 2723785 |
| CHEMBL ID | 11938 |
| SCHEMBL ID | 90036 |
| MeSH ID | M0107615 |
Synonyms (69)
| Synonym |
|---|
| einecs 218-152-3 |
| 1,4,5,6-tetrahydro-2-pyrimidinethiol |
| propylenethiourea |
| ai3-61107 |
| 3,4,5,6-tetrahydropyrimidine-2-thiol |
| 2-mercapto-3,4,5,6-tetrahydropyrimidine |
| thiourea, n,n'-1,3-propanediyl- |
| 2-mercapto-1,4,5,6-tetrahydropyrimidine |
| 3,4,5,6-tetrahydro-2-pyrimidinethiol |
| nsc 21316 |
| 3,5,6-tetrahydro-2-pyrimidinethiol |
| 2(1h)-pyrimidinethione, tetrahydro- |
| thiourea,n'-1,3-propanediyl- |
| 1,3-propylenethiourea |
| 1,5,6-tetrahydro-2-pyrimidinethiol |
| tetrahydropyrimidine-2-thione |
| 2055-46-1 |
| hexahydropyrimidine-2-thione |
| 2-mercapto-3,5,6-tetrahydropyrimidine |
| cyclic propylene thiourea |
| 2-mercaptotetrahydropyrimidine |
| 2-mercapto-1,5,6-tetrahydropyrimidine |
| nsc21316 |
| wln: t6mymtj bus |
| tetrahydro-2(1h)-pyrimidinethione |
| n,n'-trimethylenethiourea |
| nsc-21316 |
| 3,4,5,6-tetrahydro-2-pyrimidinethiol, >=99% |
| tetrahydropyrimidine-2(1h)-thione |
| STK386301 |
| 1,4,5,6-tetrahydropyrimidine-2-thiol |
| AKOS000267507 |
| CHEMBL11938 |
| STK802300 |
| 1,3-diazinane-2-thione |
| AKOS000120992 |
| unii-v3btd5l7bn |
| v3btd5l7bn , |
| A814694 |
| 2-(1h)-tetrahydropyrimidinethione |
| FT-0676434 |
| PS-4155 |
| 3,4,5,6-tetrahydro-1h-pyrimidine-2-thione |
| SCHEMBL90036 |
| BBL027546 |
| tetrahydro-2-pyrimidinethione |
| 1,4,5,6-tetrahydro-2- pyrimidinethiol |
| 3,4,5,6-tetrahydro-2-pyrimidine-thiol |
| 1,4,5,6-tetrahydropyrimidin-2-thione |
| 3,4,5,6-tetrahydro(1h)pyrimidine-2-thione |
| DTXSID3062156 |
| 1219802-05-7 |
| 1,3-propylene-d6 thiourea |
| perhydropyrimidine-2-thione |
| 3,4,5,6-tetrahydro-2(1h)-pyrimidinethione |
| 1,4,5,6-tetrahydro-pyrimidine-2-thiol |
| 2(1h)-pyrimidinethione,tetrahydro- |
| F0001-0729 |
| 3,4,5,6-teterahydro-2-pyrimidinethiol |
| mfcd00060526 |
| J-013419 |
| 93B , |
| EN300-18688 |
| AMY7063 |
| D97545 |
| trimethylenthioharnstoff |
| CS-0073474 |
| 3,4,5,6-tetrahydro-2-mercaptopyrimidine |
| SY062631 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| "For the last 30 years the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) has carried out toxicological evaluations and safety assessments of dithiocarbamate pesticides, continuously adjusting previous appraisals in the light of new data and advances in the understanding of the principles and mechanisms of toxic action of these compounds." | ( International safety assessment of pesticides: dithiocarbamate pesticides, ETU, and PTU--a review and update. Almeida, WF; Burin, GJ; Jaeger, RB; Puga, FR; Rahde, AF; Reyes, FG; Schvartsman, S; Vettorazzi, G, ) | 0.13 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID71664 | Cell growth of friend erythroleukemia cells measured as percentage of control on day 6 at a concentration of 2 mM | 1981 | Journal of medicinal chemistry, Sep, Volume: 24, Issue:9 | Cyclic urea and thiourea derivatives as inducers of murine erythroleukemia differentiation. |
| AID71672 | Percent of untreated control cell growth evaluated in friend leukemia cells on day 3 at a concentration of 2 mM | 1981 | Journal of medicinal chemistry, Sep, Volume: 24, Issue:9 | Cyclic urea and thiourea derivatives as inducers of murine erythroleukemia differentiation. |
| AID71653 | The degree of erythroid maturation was measured by assessing the proportion of benzidine-positive cells at a concentration of 2 mM | 1981 | Journal of medicinal chemistry, Sep, Volume: 24, Issue:9 | Cyclic urea and thiourea derivatives as inducers of murine erythroleukemia differentiation. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (12)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 24.38
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (24.38) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (7.14%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 13 (92.86%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||