Proteins > Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)
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Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)
[no definition available]
Synonyms
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (14)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| epigallocatechin gallate | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.2150 | 2 | 2 |
| 6-hydroxyflavone | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 30.0000 | 1 | 1 |
| epicatechin gallate | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.4000 | 1 | 1 |
| (-)-gallocatechin gallate | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.6000 | 1 | 1 |
| quercetin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.5000 | 1 | 1 |
| biochanin a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 8.0000 | 1 | 1 |
| luteolin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.0000 | 1 | 1 |
| luteolin | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 11.5000 | 1 | 1 |
| genistein | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 7.0000 | 1 | 1 |
| fisetin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.0000 | 1 | 1 |
| morin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 8.0000 | 1 | 1 |
| myricetin | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.0000 | 1 | 1 |
| daidzein | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 30.0000 | 1 | 1 |
| 7-hydroxyflavone | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 20.0000 | 1 | 1 |
| (-)-catechin-3-O-gallate | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.4000 | 1 | 1 |
| (-)-catechin-3-O-gallate | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 2.8000 | 1 | 1 |
Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI).Journal of medicinal chemistry, , Oct-10, Volume: 56, Issue:19, 2013
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.Journal of medicinal chemistry, , Jun-01, Volume: 49, Issue:11, 2006