Compounds > corticotropin-like intermediate lobe peptide
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corticotropin-like intermediate lobe peptide
Description
Corticotropin-Like Intermediate Lobe Peptide: A peptide derived from the cleavage of ADRENOCORTICOTROPIC HORMONE, found primarily in the INTERMEDIATE LOBE OF PITUITARY but also in the ARCUATE NUCLEUS of basal HYPOTHALAMUS. Its sequence is identical to the C-terminal 22-amino acids of ACTH or ACTH 18-39. [MeSH]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 16133227 |
| MeSH ID | M0066247 |
Synonyms (6)
| Synonym |
|---|
| corticotropin-like intermediate lobe peptide |
| 53917-42-3 |
| FT-0688964 |
| corticotropin-like intermediate peptide |
| Q1753256 |
| clip (human) |
Research
Studies (87)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 48 (55.17) | 18.7374 |
| 1990's | 20 (22.99) | 18.2507 |
| 2000's | 11 (12.64) | 29.6817 |
| 2010's | 7 (8.05) | 24.3611 |
| 2020's | 1 (1.15) | 2.80 |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 4 (4.35%) | 6.00% |
| Case Studies | 1 (1.09%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 87 (94.57%) | 84.16% |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|
| ACTH Syndrome, Ectopic | 0 | | 1980 | 2016 | 29.0 | low | 0 | 2 | 0 | 0 | 1 | 0 |
| Adenoma | 0 | | 1989 | 1994 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Adenoma, Basal Cell | 0 | | 1989 | 1994 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Adrenal Cancer | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Adrenocorticotropic Hormone, Inappropriate Secretion | 0 | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Aging | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Alloxan Diabetes | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Anoxemia | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Argentaffinoma | 0 | | 1989 | 2001 | 29.3 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Atypical Ductal Hyperplasia | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Body Weight | 0 | | 1987 | 1993 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Breast Cancer | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Breast Neoplasms | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Bronchial Neoplasms | 0 | | 1989 | 1994 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Cancer of Lung | 0 | | 1994 | 2001 | 26.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Cancer of Pituitary | 0 | | 1989 | 1994 | 31.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Cancer of the Thymus | 0 | | 1989 | 1994 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Carcinoid Tumor | 0 | | 1989 | 2001 | 29.3 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Carcinoma in Situ | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Intraductal, Noninfiltrating | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Intraepithelial | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Oat Cell | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Carcinoma, Small Cell | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Chronic Insomnia | 0 | | 1990 | 2018 | 20.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Cushing Syndrome | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cushing's Syndrome | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Diabetes Mellitus | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Disease Models, Animal | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Drug Withdrawal Symptoms | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Ectopic ACTH Syndrome | 0 | | 1980 | 2016 | 29.0 | low | 0 | 2 | 0 | 0 | 1 | 0 |
| Ectopic Hormone Syndromes | 0 | | 1980 | 1989 | 39.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Equine Diseases | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Glial Cell Tumors | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Glioma | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Heroin Abuse | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Heroin Dependence | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperglycemia | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperglycemia, Postprandial | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypoxia | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Inadequate Sleep | 0 | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Long Sleeper Syndrome | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Lung Neoplasms | 0 | | 1994 | 2001 | 26.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Neoplasms, Bronchial | 0 | | 1989 | 1994 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Obesity | 0 | | 1987 | 1987 | 37.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Pheochromocytoma | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Pheochromocytoma, Extra-Adrenal | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Pituitary ACTH Hypersecretion | 0 | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Pituitary Neoplasms | 0 | | 1989 | 1994 | 31.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Pregnancy | 0 | | 1981 | 1995 | 38.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Sensitivity and Specificity | 0 | | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Sleep Initiation and Maintenance Disorders | 0 | | 1990 | 2018 | 20.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Sleep Wake Disorders | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Substance Withdrawal Syndrome | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Thymus Neoplasms | 0 | | 1989 | 1994 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
60 YEARS OF POMC: Purification and biological characterisation of melanotrophins and corticotrophins.Journal of molecular endocrinology, , Volume: 56, Issue:4, 2016
Corticotrophin-like intermediary lobe peptide as a marker of alternate pro-opiomelanocortin processing in ACTH-producing non-pituitary tumours.Clinical endocrinology, , Volume: 31, Issue:6, 1989
ACTH LPH and related peptides in the ectopic ACTH syndrome.Clinical endocrinology, , Volume: 13, Issue:5, 1980
Elevated plasma level of lipotropin revealing an occult carcinoid tumor with normal plasma adrenocorticotropin.The Journal of clinical endocrinology and metabolism, , Volume: 86, Issue:7, 2001
Expression of the prohormone convertase PC2 correlates with the presence of corticotropin-like intermediate lobe peptide in human adrenocorticotropin-secreting tumors.The Journal of clinical endocrinology and metabolism, , Volume: 79, Issue:5, 1994
Corticotrophin-like intermediary lobe peptide as a marker of alternate pro-opiomelanocortin processing in ACTH-producing non-pituitary tumours.Clinical endocrinology, , Volume: 31, Issue:6, 1989
Phosphorylated forms of adrenocorticotropin and corticotropin-like intermediary lobe peptide in human tumors.European journal of endocrinology, , Volume: 131, Issue:4, 1994
Expression of the prohormone convertase PC2 correlates with the presence of corticotropin-like intermediate lobe peptide in human adrenocorticotropin-secreting tumors.The Journal of clinical endocrinology and metabolism, , Volume: 79, Issue:5, 1994
Corticotrophin-like intermediary lobe peptide as a marker of alternate pro-opiomelanocortin processing in ACTH-producing non-pituitary tumours.Clinical endocrinology, , Volume: 31, Issue:6, 1989
Changes in plasma beta-cell tropin concentrations during pregnancy in rats.The Journal of endocrinology, , Volume: 146, Issue:1, 1995
Functional morphology of the human fetal pituitary.Pathology annual, , Volume: 19 Pt 1, 1984
[The role of the fetus in labor].Duodecim; laaketieteellinen aikakauskirja, , Volume: 98, Issue:9, 1982
The pars intermedia and the fetal pituitary-adrenal axis.Ciba Foundation symposium, , Volume: 81, 1981
60 YEARS OF POMC: Purification and biological characterisation of melanotrophins and corticotrophins.Journal of molecular endocrinology, , Volume: 56, Issue:4, 2016
Corticotrophin-like intermediary lobe peptide as a marker of alternate pro-opiomelanocortin processing in ACTH-producing non-pituitary tumours.Clinical endocrinology, , Volume: 31, Issue:6, 1989
ACTH LPH and related peptides in the ectopic ACTH syndrome.Clinical endocrinology, , Volume: 13, Issue:5, 1980
Elevated plasma level of lipotropin revealing an occult carcinoid tumor with normal plasma adrenocorticotropin.The Journal of clinical endocrinology and metabolism, , Volume: 86, Issue:7, 2001
Expression of the prohormone convertase PC2 correlates with the presence of corticotropin-like intermediate lobe peptide in human adrenocorticotropin-secreting tumors.The Journal of clinical endocrinology and metabolism, , Volume: 79, Issue:5, 1994
Corticotrophin-like intermediary lobe peptide as a marker of alternate pro-opiomelanocortin processing in ACTH-producing non-pituitary tumours.Clinical endocrinology, , Volume: 31, Issue:6, 1989
Expression of the prohormone convertase PC2 correlates with the presence of corticotropin-like intermediate lobe peptide in human adrenocorticotropin-secreting tumors.The Journal of clinical endocrinology and metabolism, , Volume: 79, Issue:5, 1994
Phosphorylated forms of adrenocorticotropin and corticotropin-like intermediary lobe peptide in human tumors.European journal of endocrinology, , Volume: 131, Issue:4, 1994
Corticotrophin-like intermediary lobe peptide as a marker of alternate pro-opiomelanocortin processing in ACTH-producing non-pituitary tumours.Clinical endocrinology, , Volume: 31, Issue:6, 1989
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