zonisamide has been researched along with Sensitivity and Specificity in 6 studies
Zonisamide: A benzisoxazole and sulfonamide derivative that acts as a CALCIUM CHANNEL blocker. It is used primarily as an adjunctive antiepileptic agent for the treatment of PARTIAL SEIZURES, with or without secondary generalization.
zonisamide : A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zonisamide (ZNS) is an anticonvulsant (AC) that contains a sulpha moiety potentially triggering hypersensitivity syndrome reactions (HSR)." | 1.35 | Predicting possible zonisamide hypersensitivity syndrome. ( Cohen, L; Kessas, M; Lee, AW; Malkiewicz, IM; Neuman, MG; Shear, NH, 2008) |
| " The developed assay method was applied to a pharmacokinetic study in human volunteers." | 1.35 | Simultaneous estimation of four proton pump inhibitors--lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study. ( Bharathi, DV; Chatki, PK; Hotha, KK; Jagadeesh, B; Mullangi, R; Naidu, A; Thriveni, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neuman, MG | 1 |
| Shear, NH | 1 |
| Malkiewicz, IM | 1 |
| Kessas, M | 1 |
| Lee, AW | 1 |
| Cohen, L | 1 |
| Bharathi, DV | 1 |
| Hotha, KK | 1 |
| Jagadeesh, B | 1 |
| Chatki, PK | 1 |
| Thriveni, K | 1 |
| Mullangi, R | 1 |
| Naidu, A | 1 |
| Antonilli, L | 1 |
| Brusadin, V | 1 |
| Filipponi, F | 1 |
| Guglielmi, R | 1 |
| Nencini, P | 1 |
| Greiner-Sosanko, E | 1 |
| Lower, DR | 1 |
| Virji, MA | 1 |
| Krasowski, MD | 1 |
| Vermeij, TA | 1 |
| Edelbroek, PM | 1 |
| Okumura, A | 1 |
| Ishihara, N | 1 |
| Kato, T | 1 |
| Hayakawa, F | 1 |
| Kuno, K | 1 |
| Watanabe, K | 1 |
1 trial available for zonisamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide.
Topics: Acetylcholine; Anticonvulsants; Child; Child, Preschool; Cholinergic Agents; Epilepsy; False Positiv | 2000 |
5 other studies available for zonisamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Predicting possible zonisamide hypersensitivity syndrome.
Topics: Adult; Age Factors; Aged; Animals; Anticonvulsants; Cell Survival; Diagnostic Techniques and Procedu | 2008 |
Simultaneous estimation of four proton pump inhibitors--lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chromatography, High Pressure Liquid; Drug Stability; Human | 2009 |
Development and validation of an analytical method based on high performance thin layer chromatography for the simultaneous determination of lamotrigine, zonisamide and levetiracetam in human plasma.
Topics: Anticonvulsants; Calibration; Chromatography, Thin Layer; Drug Monitoring; Humans; Isoxazoles; Lamot | 2011 |
Simultaneous determination of lamotrigine, zonisamide, and carbamazepine in human plasma by high-performance liquid chromatography.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Isoxazoles; Lam | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure | 2007 |