A choline O-acetyltransferase that is encoded in the genome of rat. [PRO:DNx]
CHOACTase;
ChAT;
Choline acetylase;
EC 2.3.1.6
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 1-butanol | Rattus norvegicus (Norway rat) | Ki | 47,000.0000 | 1 | 1 |
| dimethyl sulfoxide | Rattus norvegicus (Norway rat) | Ki | 25,000.0000 | 1 | 1 |
| tacrine | Rattus norvegicus (Norway rat) | Ki | 0.0002 | 1 | 1 |
| donepezil | Rattus norvegicus (Norway rat) | IC50 | 0.0053 | 1 | 1 |
| choline chloride | Rattus norvegicus (Norway rat) | Ki | 4,000.0000 | 2 | 2 |
| dimethyl sulfone | Rattus norvegicus (Norway rat) | Ki | 144,000.0000 | 2 | 2 |
| acrylic acid | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| deanol | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| 3,3-dimethylbutan-1-ol | Rattus norvegicus (Norway rat) | Ki | 13,250.0000 | 2 | 2 |
| methylthioethanol | Rattus norvegicus (Norway rat) | Ki | 40,000.0000 | 1 | 1 |
| n,n-dimethylepinephrine | Rattus norvegicus (Norway rat) | Ki | 25,000.0000 | 1 | 1 |
| norbinaltorphimine | Rattus norvegicus (Norway rat) | Ki | 0.0008 | 1 | 1 |
| pf-04455242 | Rattus norvegicus (Norway rat) | Ki | 0.0030 | 1 | 1 |
| asoxime chloride | Rattus norvegicus (Norway rat) | IC50 | 802.7000 | 1 | 1 |
| pralidoxime chloride | Rattus norvegicus (Norway rat) | IC50 | 184.7000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 1-butanol | Rattus norvegicus (Norway rat) | Km | 13,000.0000 | 1 | 1 |
| choline | Rattus norvegicus (Norway rat) | Km | 290.0000 | 1 | 1 |
| hemicholinium 3 | Rattus norvegicus (Norway rat) | Km | 1,210.0000 | 1 | 1 |
| choline chloride | Rattus norvegicus (Norway rat) | Km | 330.0000 | 1 | 1 |
| 3,3-dimethylbutan-1-ol | Rattus norvegicus (Norway rat) | Km | 5,300.0000 | 1 | 1 |
| methylthioethanol | Rattus norvegicus (Norway rat) | Km | 15,000.0000 | 1 | 1 |