normetanephrine has been researched along with Sensitivity and Specificity in 46 studies
Normetanephrine: A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "AUC = area under curve; CI = confidence interval; DOR = diagnostic odds ratio; EIA = enzyme immunoassay; LC-ECD = liquid chromatography-electrochemical detection; LC-MS/MS = liquid chromatography-tandem mass spectrometry; MN = metanephrine; NMN = normetaneprhine; PPGL = pheochromocytoma and paraganglioma; QUADAS-2 = Quality Assessment of Diagnostic Accuracy Studies 2." | 8.95 | ACCURACY OF PLASMA FREE METANEPHRINES IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA AND PARAGANGLIOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS. ( Cao, X; Chen, Y; Huang, X; Li, Y; Xiao, H; Zhou, X, 2017) |
| "Sampling of blood in the supine position for diagnosis of pheochromocytoma and paraganglioma (PPGL) results in lower rates of false positives for plasma normetanephrine than seated sampling." | 8.12 | Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma. ( Amar, L; Baron, S; Blanchard, A; Braun, L; Ceccato, F; Davies, E; Deinum, J; Deutschbein, T; Dobrowolski, P; Eisenhofer, G; Fassnacht, M; Gruber, S; Hampson, S; Januszewicz, A; Lenzini, L; Müller, LM; Nölting, S; Pamporaki, C; Pecori, A; Peitzsch, M; Pommer, G; Prejbisz, A; Remde, H; Rossi, GP; Stell, A; Timmers, HJLM; Zennaro, MC, 2022) |
| "Urinary measurement of fractionated metanephrines is one of the best available biochemical tests for the diagnosis of pheochromocytoma and paraganglioma; however, false-positive results remain an issue." | 7.96 | Clinical factors affecting spot urine fractionated metanephrines in patients suspected pheochromocytoma/paraganglioma. ( Bokuda, K; Ichihara, A; Seki, Y; Yatabe, M, 2020) |
| "Measuring the levels of the plasma free metanephrines (PFMs) represents a recently developed and promising test for the diagnosis of pheochromocytoma in the United States and Europe." | 7.80 | Plasma free metanephrines in the diagnosis of pheochromocytoma: diagnostic accuracy and strategies for Japanese patients. ( Adachi, M; Arai, Y; Hara, H; Hashimoto, K; Hataya, Y; Ikeda, Y; Imai, T; Isobe, K; Kamide, K; Kato, T; Kawakami, Y; Kikumori, T; Ma, E; Maeda, Y; Matsuda, T; Midorikawa, S; Okada, Y; Sakurai, A; Shimano, H; Takahashi, H; Takekoshi, K; Tanaka, Y; Yanase, T; Yokoyama, C, 2014) |
| "The purpose of this study was to investigate the utility of measurement of plasma free metanephrines in dogs for the diagnosis of pheochromocytoma." | 7.79 | Comparison of plasma free metanephrines between healthy dogs and 3 dogs with pheochromocytoma. ( Frank, EL; Green, BA, 2013) |
| " Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity." | 7.78 | Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012) |
| "Plasma free and urinary metanephrines are recognized biomarkers for the assessment of pheochromocytoma." | 7.76 | Diagnostic accuracy of free and total metanephrines in plasma and fractionated metanephrines in urine of patients with pheochromocytoma. ( Baudin, E; Buclin, T; Drouard-Troalen, L; Grand, D; Grouzmann, E; Muller, B; Plouin, PF, 2010) |
| "Measurement of 24-h urinary fractionated metanephrines by a tandem mass spectrometry assay appears to be an effective biochemical technique in the investigation of pheochromocytoma." | 7.74 | The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma. ( Bajnarek, J; Perry, CG; Sawka, AM; Singh, R; Thabane, L; Young, WF, 2007) |
| "Measurements of plasma free metanephrines (normetanephrine and metanephrine) provide a useful test for diagnosis of pheochromocytoma and may provide other information about the nature of these tumors." | 7.73 | Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines. ( Brouwers, FM; Csako, G; Eisenhofer, G; Goldstein, DS; Lenders, JW; Mannelli, M; Pacak, K; Walther, MM, 2005) |
| "The sensitivity and specificity of the MS/MS method for urinary conjugated metanephrines offer advantages over colorimetric, immunoassay, HPLC, and gas chromatography-mass spectrometry methods because of elimination of drug interferences, high throughput, and short chromatographic run time." | 7.71 | Validation of liquid chromatography-tandem mass spectrometry method for analysis of urinary conjugated metanephrine and normetanephrine for screening of pheochromocytoma. ( Singh, RJ; Taylor, RL, 2002) |
| "Measurements of plasma normetanephrine and metanephrine are useful in screening for pheochromocytomas in patients with a familial predisposition to these tumors." | 7.70 | Plasma normetanephrine and metanephrine for detecting pheochromocytoma in von Hippel-Lindau disease and multiple endocrine neoplasia type 2. ( Eisenhofer, G; Goldstein, DS; Keiser, HR; Lenders, JW; Linehan, WM; Walther, MM, 1999) |
| "Amoxicillin interference was assessed by comparison for co-elution with uNMN and by LC-MS/MS analysis." | 5.40 | Amoxicillin-associated interference in an HPLC-EC assay for urinary fractionated metanephrines: potential pitfall in pheochromocytoma biochemical diagnosis. ( Alpigiani, MG; Barco, S; Cangemi, G; Ghiggeri, GM; Maffia, A; Talio, M; Tripodi, G, 2014) |
| "Plasma-free metanephrines measured by EIA have better diagnostic test characteristics than urinary catecholamines in the diagnosis of pheochromocytoma." | 5.14 | Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors. ( Akker, SA; Burrin, J; Chew, SL; Drake, WM; Finney, H; Grossman, AB; Procopiou, M, 2009) |
| "AUC = area under curve; CI = confidence interval; DOR = diagnostic odds ratio; EIA = enzyme immunoassay; LC-ECD = liquid chromatography-electrochemical detection; LC-MS/MS = liquid chromatography-tandem mass spectrometry; MN = metanephrine; NMN = normetaneprhine; PPGL = pheochromocytoma and paraganglioma; QUADAS-2 = Quality Assessment of Diagnostic Accuracy Studies 2." | 4.95 | ACCURACY OF PLASMA FREE METANEPHRINES IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA AND PARAGANGLIOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS. ( Cao, X; Chen, Y; Huang, X; Li, Y; Xiao, H; Zhou, X, 2017) |
| "We previously highlighted the problem of frequent false positives in 24 h urine normetanephrine(UNM) measurements owing to reference intervals that are inappropriately low for the population being screened for pheochromocytoma." | 4.12 | Updated reference intervals for urine normetanephrine have no effect on test sensitivity but fewer false positives. ( Boyd, J; Dong, Y; Hyrcza, M; Kline, GA; Leung, AAC; Pacaud, D; Pasieka, JL; Sadrzadeh, HSM, 2022) |
| "Sampling of blood in the supine position for diagnosis of pheochromocytoma and paraganglioma (PPGL) results in lower rates of false positives for plasma normetanephrine than seated sampling." | 4.12 | Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma. ( Amar, L; Baron, S; Blanchard, A; Braun, L; Ceccato, F; Davies, E; Deinum, J; Deutschbein, T; Dobrowolski, P; Eisenhofer, G; Fassnacht, M; Gruber, S; Hampson, S; Januszewicz, A; Lenzini, L; Müller, LM; Nölting, S; Pamporaki, C; Pecori, A; Peitzsch, M; Pommer, G; Prejbisz, A; Remde, H; Rossi, GP; Stell, A; Timmers, HJLM; Zennaro, MC, 2022) |
| "Urinary measurement of fractionated metanephrines is one of the best available biochemical tests for the diagnosis of pheochromocytoma and paraganglioma; however, false-positive results remain an issue." | 3.96 | Clinical factors affecting spot urine fractionated metanephrines in patients suspected pheochromocytoma/paraganglioma. ( Bokuda, K; Ichihara, A; Seki, Y; Yatabe, M, 2020) |
| "Measurement of plasma/urinary catecholamine metabolites--especially normetanephrine (NMN)--represents a gold standard in biochemical detection of succinate dehydrogenase subunit B (SDHB) and D (SDHD)-related pheochromocytomas (PHEO) and paragangliomas (PGL)." | 3.80 | Clinical utility of chromogranin A in SDHx-related paragangliomas. ( Eisenhofer, G; Kantorovich, V; Pacak, K; Prodanov, T; Wesley, R; Zuber, S, 2014) |
| "Measuring the levels of the plasma free metanephrines (PFMs) represents a recently developed and promising test for the diagnosis of pheochromocytoma in the United States and Europe." | 3.80 | Plasma free metanephrines in the diagnosis of pheochromocytoma: diagnostic accuracy and strategies for Japanese patients. ( Adachi, M; Arai, Y; Hara, H; Hashimoto, K; Hataya, Y; Ikeda, Y; Imai, T; Isobe, K; Kamide, K; Kato, T; Kawakami, Y; Kikumori, T; Ma, E; Maeda, Y; Matsuda, T; Midorikawa, S; Okada, Y; Sakurai, A; Shimano, H; Takahashi, H; Takekoshi, K; Tanaka, Y; Yanase, T; Yokoyama, C, 2014) |
| "The purpose of this study was to investigate the utility of measurement of plasma free metanephrines in dogs for the diagnosis of pheochromocytoma." | 3.79 | Comparison of plasma free metanephrines between healthy dogs and 3 dogs with pheochromocytoma. ( Frank, EL; Green, BA, 2013) |
| " Determination of metanephrines by high-pressure liquid chromatography has been well established for the diagnosis of pheochromocytomas, demonstrating high sensitivity and specificity." | 3.78 | Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass. ( Deutschbein, T; Hinrichs, J; Mann, K; Petersenn, S; Schmidt, H; Unger, N; Walz, MK, 2012) |
| "Plasma free and urinary metanephrines are recognized biomarkers for the assessment of pheochromocytoma." | 3.76 | Diagnostic accuracy of free and total metanephrines in plasma and fractionated metanephrines in urine of patients with pheochromocytoma. ( Baudin, E; Buclin, T; Drouard-Troalen, L; Grand, D; Grouzmann, E; Muller, B; Plouin, PF, 2010) |
| "Measurement of 24-h urinary fractionated metanephrines by a tandem mass spectrometry assay appears to be an effective biochemical technique in the investigation of pheochromocytoma." | 3.74 | The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma. ( Bajnarek, J; Perry, CG; Sawka, AM; Singh, R; Thabane, L; Young, WF, 2007) |
| "Measurements of plasma free metanephrines (normetanephrine and metanephrine) provide a useful test for diagnosis of pheochromocytoma and may provide other information about the nature of these tumors." | 3.73 | Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines. ( Brouwers, FM; Csako, G; Eisenhofer, G; Goldstein, DS; Lenders, JW; Mannelli, M; Pacak, K; Walther, MM, 2005) |
| "combined determination of normetanephrine with vanillylmandelic acid (0-1 year) or homovanillic acid (1-5 years and 5-10 years) further enhanced the diagnostic power up to 100% sensitivity and specificity of the testing depending on the age group." | 3.72 | Comparative values of catecholamines and metabolites for the diagnosis of neuroblastoma. ( Corcuff, JB; Monsaingeon, M; Perel, Y; Simonnet, G, 2003) |
| "The sensitivity and specificity of the MS/MS method for urinary conjugated metanephrines offer advantages over colorimetric, immunoassay, HPLC, and gas chromatography-mass spectrometry methods because of elimination of drug interferences, high throughput, and short chromatographic run time." | 3.71 | Validation of liquid chromatography-tandem mass spectrometry method for analysis of urinary conjugated metanephrine and normetanephrine for screening of pheochromocytoma. ( Singh, RJ; Taylor, RL, 2002) |
| "Measurements of plasma normetanephrine and metanephrine are useful in screening for pheochromocytomas in patients with a familial predisposition to these tumors." | 3.70 | Plasma normetanephrine and metanephrine for detecting pheochromocytoma in von Hippel-Lindau disease and multiple endocrine neoplasia type 2. ( Eisenhofer, G; Goldstein, DS; Keiser, HR; Lenders, JW; Linehan, WM; Walther, MM, 1999) |
| " Overnight catecholamines, metanephrines, and 4-hydroxy-3-methoxymandelic acid (HMMA) levels were measured in 16 patients with histologically confirmed pheochromocytomas, 166 patients with hypertension, and 24 normotensive subjects." | 3.69 | Overnight excretion of urinary catecholamines and metabolites in the detection of pheochromocytoma. ( Lai, LC; Lennard, TW; Peaston, RT, 1996) |
| "Determination of urinary 3-O-methylated catecholamines (metanephrines) is generally considered a principal test for the clinical chemical diagnosis of pheochromocytoma and is currently performed predominantly with chromatographic techniques such as gas-liquid chromatography and HPLC." | 3.69 | Evaluation of urinary metanephrine and normetanephrine enzyme immunoassay (ELISA) kits by comparison with isotope dilution mass spectrometry. ( Kema, IP; Manz, B; Volmer, M; Wesemann, R; Westermann, J; Wolthers, BG, 1997) |
| "Pheochromocytoma is a hormonally active tumour originating from neuroendocrine cells of the adrenal medulla." | 1.72 | ProSAAS peptide of the granin protein family in biochemical diagnostics of pheochromocytoma. ( Glinicki, P; Ostrowska, M; Papierska, L; Zgliczyński, W, 2022) |
| "Amoxicillin interference was assessed by comparison for co-elution with uNMN and by LC-MS/MS analysis." | 1.40 | Amoxicillin-associated interference in an HPLC-EC assay for urinary fractionated metanephrines: potential pitfall in pheochromocytoma biochemical diagnosis. ( Alpigiani, MG; Barco, S; Cangemi, G; Ghiggeri, GM; Maffia, A; Talio, M; Tripodi, G, 2014) |
| " In this work, a UPLC/ MS/MS-based method combined with a diethyl labeling technique was developed for simultaneous determination of a panel of monoamines in rat prefrontal cortex microdialysates." | 1.35 | Diethylation labeling combined with UPLC/MS/MS for simultaneous determination of a panel of monoamine neurotransmitters in rat prefrontal cortex microdialysates. ( El-Kattan, AF; Fountain, S; Ji, C; Kozak, R; Lepsy, C; Li, W; Ren, XD, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (19.57) | 18.2507 |
| 2000's | 14 (30.43) | 29.6817 |
| 2010's | 19 (41.30) | 24.3611 |
| 2020's | 4 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Kline, GA | 1 |
| Boyd, J | 1 |
| Hyrcza, M | 1 |
| Pacaud, D | 1 |
| Pasieka, JL | 1 |
| Dong, Y | 1 |
| Sadrzadeh, HSM | 1 |
| Leung, AAC | 1 |
| Glinicki, P | 1 |
| Ostrowska, M | 1 |
| Papierska, L | 1 |
| Zgliczyński, W | 1 |
| Pommer, G | 1 |
| Pamporaki, C | 2 |
| Peitzsch, M | 2 |
| Remde, H | 1 |
| Deutschbein, T | 2 |
| Nölting, S | 1 |
| Müller, LM | 1 |
| Braun, L | 1 |
| Gruber, S | 1 |
| Pecori, A | 1 |
| Hampson, S | 1 |
| Davies, E | 1 |
| Stell, A | 1 |
| Rossi, GP | 1 |
| Lenzini, L | 1 |
| Ceccato, F | 1 |
| Timmers, HJLM | 1 |
| Deinum, J | 2 |
| Amar, L | 1 |
| Blanchard, A | 1 |
| Baron, S | 1 |
| Fassnacht, M | 1 |
| Dobrowolski, P | 1 |
| Januszewicz, A | 3 |
| Zennaro, MC | 1 |
| Prejbisz, A | 3 |
| Eisenhofer, G | 9 |
| Takekoshi, K | 2 |
| Satoh, F | 1 |
| Tanabe, A | 1 |
| Okamoto, T | 2 |
| Ichihara, A | 2 |
| Tsuiki, M | 1 |
| Katabami, T | 1 |
| Nomura, M | 1 |
| Tanaka, T | 1 |
| Matsuda, T | 2 |
| Imai, T | 2 |
| Yamada, M | 1 |
| Asada, S | 1 |
| Kawata, N | 1 |
| Naruse, M | 1 |
| Bokuda, K | 1 |
| Yatabe, M | 1 |
| Seki, Y | 1 |
| Chen, Y | 1 |
| Xiao, H | 2 |
| Zhou, X | 1 |
| Huang, X | 1 |
| Li, Y | 1 |
| Cao, X | 1 |
| Srithunyarat, T | 1 |
| Svensson, A | 1 |
| Hanås, S | 1 |
| Höglund, OV | 1 |
| Hagman, R | 1 |
| Lilliehöök, I | 1 |
| Olsson, U | 1 |
| Ljungvall, I | 1 |
| Häggström, J | 1 |
| Ström Holst, B | 1 |
| Pettersson, A | 1 |
| Höglund, K | 1 |
| Jeyaraman, K | 1 |
| Natarajan, V | 1 |
| Thomas, N | 1 |
| Jacob, PM | 1 |
| Nair, A | 1 |
| Shanthly, N | 1 |
| Oommen, R | 1 |
| Varghese, G | 1 |
| Joseph, FJ | 1 |
| Seshadri, MS | 1 |
| Rajaratnam, S | 1 |
| Brossaud, J | 1 |
| Gosse, P | 1 |
| Gatta, B | 1 |
| Tabarin, A | 1 |
| Simonnet, G | 2 |
| Corcuff, JB | 2 |
| Därr, R | 4 |
| Miehle, K | 1 |
| Peczkowska, M | 1 |
| Weismann, D | 1 |
| Beuschlein, F | 1 |
| Sinnott, R | 1 |
| Bornstein, SR | 3 |
| Neumann, HP | 1 |
| Lenders, J | 1 |
| Green, BA | 1 |
| Frank, EL | 1 |
| Zuber, S | 1 |
| Wesley, R | 1 |
| Prodanov, T | 1 |
| Pacak, K | 4 |
| Kantorovich, V | 1 |
| Tanaka, Y | 1 |
| Isobe, K | 1 |
| Ma, E | 1 |
| Kikumori, T | 1 |
| Maeda, Y | 1 |
| Sakurai, A | 1 |
| Midorikawa, S | 1 |
| Hataya, Y | 1 |
| Kato, T | 1 |
| Kamide, K | 1 |
| Ikeda, Y | 1 |
| Okada, Y | 1 |
| Adachi, M | 1 |
| Yanase, T | 1 |
| Takahashi, H | 1 |
| Yokoyama, C | 1 |
| Arai, Y | 1 |
| Hashimoto, K | 1 |
| Shimano, H | 1 |
| Hara, H | 1 |
| Kawakami, Y | 1 |
| Barco, S | 1 |
| Alpigiani, MG | 1 |
| Ghiggeri, GM | 1 |
| Talio, M | 1 |
| Maffia, A | 1 |
| Tripodi, G | 1 |
| Cangemi, G | 1 |
| Balog, B | 1 |
| Tőke, J | 1 |
| Róna, K | 1 |
| Szücs, N | 1 |
| Igaz, P | 1 |
| Pusztai, P | 1 |
| Sármán, B | 1 |
| Gláz, E | 1 |
| Kiss, R | 1 |
| Patócs, A | 1 |
| Rácz, K | 1 |
| Tóth, M | 1 |
| Cho, YY | 1 |
| Song, KH | 1 |
| Kim, YN | 1 |
| Ahn, SH | 1 |
| Kim, H | 1 |
| Park, S | 1 |
| Suh, S | 1 |
| Kim, BJ | 1 |
| Lee, SY | 2 |
| Chun, S | 1 |
| Koh, JM | 1 |
| Lee, SH | 1 |
| Kim, JH | 3 |
| Procopiou, M | 1 |
| Finney, H | 1 |
| Akker, SA | 1 |
| Chew, SL | 1 |
| Drake, WM | 1 |
| Burrin, J | 1 |
| Grossman, AB | 1 |
| Ji, C | 1 |
| Li, W | 1 |
| Ren, XD | 1 |
| El-Kattan, AF | 1 |
| Kozak, R | 1 |
| Fountain, S | 1 |
| Lepsy, C | 1 |
| Xu, Z | 1 |
| Okada, J | 1 |
| Timerbaev, AR | 1 |
| Hirokawa, T | 1 |
| Grouzmann, E | 1 |
| Drouard-Troalen, L | 1 |
| Baudin, E | 1 |
| Plouin, PF | 1 |
| Muller, B | 1 |
| Grand, D | 1 |
| Buclin, T | 1 |
| Kotzerke, J | 1 |
| Zöphel, K | 1 |
| Stroszczynski, C | 1 |
| Schultze Kool, LJ | 1 |
| Pistorius, S | 1 |
| Neumann, H | 1 |
| Hofbauer, LC | 2 |
| Mullins, F | 1 |
| O'Shea, P | 1 |
| FitzGerald, R | 1 |
| Tormey, W | 1 |
| Unger, N | 1 |
| Hinrichs, J | 1 |
| Schmidt, H | 1 |
| Walz, MK | 1 |
| Mann, K | 1 |
| Petersenn, S | 1 |
| Sohn, SY | 1 |
| Park, HD | 1 |
| Jung, BC | 1 |
| Kim, HJ | 1 |
| Jang, HW | 1 |
| Kim, KW | 1 |
| Lee, MK | 1 |
| Min, YK | 1 |
| Lattke, P | 1 |
| Herberg, M | 1 |
| Siegert, G | 1 |
| Qin, N | 1 |
| Hoyer, J | 1 |
| Villringer, A | 1 |
| Remaley, A | 1 |
| Martucci, V | 1 |
| Ross, HA | 3 |
| Sweep, FC | 1 |
| Lenders, JW | 4 |
| Stange, K | 1 |
| Kindel, B | 1 |
| Shargorodsky, M | 1 |
| Zimlichman, R | 1 |
| Monsaingeon, M | 1 |
| Perel, Y | 1 |
| Lagerstedt, SA | 1 |
| O'Kane, DJ | 1 |
| Singh, RJ | 2 |
| Goldstein, DS | 3 |
| Mannelli, M | 1 |
| Csako, G | 1 |
| Walther, MM | 2 |
| Brouwers, FM | 1 |
| Grossrubatscher, E | 1 |
| Dalino, P | 1 |
| Vignati, F | 1 |
| Gambacorta, M | 1 |
| Pugliese, R | 1 |
| Boniardi, M | 1 |
| Rossetti, O | 1 |
| Marocchi, A | 1 |
| Bertuzzi, M | 1 |
| Loli, P | 1 |
| Perry, CG | 1 |
| Sawka, AM | 1 |
| Singh, R | 1 |
| Thabane, L | 1 |
| Bajnarek, J | 1 |
| Young, WF | 1 |
| Radjaipour, M | 1 |
| Raster, H | 1 |
| Liebich, HM | 1 |
| Peaston, RT | 1 |
| Lennard, TW | 1 |
| Lai, LC | 1 |
| Wolthers, BG | 3 |
| Kema, IP | 3 |
| Volmer, M | 1 |
| Wesemann, R | 1 |
| Westermann, J | 1 |
| Manz, B | 1 |
| Hay, M | 1 |
| Mormède, P | 1 |
| Ito, Y | 1 |
| Obara, T | 1 |
| Kanbe, M | 1 |
| Tanaka, R | 1 |
| Iihara, M | 1 |
| Okamoto, J | 1 |
| Yamazaki, K | 1 |
| Jibiki, K | 1 |
| Tsunoda, M | 1 |
| Takezawa, K | 1 |
| Santa, T | 1 |
| Imai, K | 1 |
| Linehan, WM | 1 |
| Keiser, HR | 1 |
| Chan, EC | 1 |
| Ho, PC | 1 |
| Willemsen, JJ | 2 |
| Sweep, CG | 2 |
| Doppman, JL | 1 |
| Shulkin, BL | 1 |
| Udelsman, R | 1 |
| Taylor, RL | 1 |
| Candito, M | 1 |
| Thyss, A | 1 |
| Albertini, M | 1 |
| Deville, A | 1 |
| Politano, S | 1 |
| Mariani, R | 1 |
| Chambon, P | 1 |
| Gallacher, G | 1 |
| Mellor, GW | 1 |
| Landon, J | 1 |
| Sjostrom, L | 1 |
1 review available for normetanephrine and Sensitivity and Specificity
| Article | Year |
|---|---|
ACCURACY OF PLASMA FREE METANEPHRINES IN THE DIAGNOSIS OF PHEOCHROMOCYTOMA AND PARAGANGLIOMA: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Topics: Adrenal Gland Neoplasms; Biomarkers; Chromatography, Liquid; Humans; Immunoenzyme Techniques; Metane | 2017 |
3 trials available for normetanephrine and Sensitivity and Specificity
| Article | Year |
|---|---|
Correlation between urinary fractionated metanephrines in 24-hour and spot urine samples for evaluating the therapeutic effect of metyrosine: a subanalysis of a multicenter, open-label phase I/II study.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Child; Fe | 2019 |
Biochemical diagnosis of phaeochromocytoma using plasma-free normetanephrine, metanephrine and methoxytyramine: importance of supine sampling under fasting conditions.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Blood Specim | 2014 |
Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Catecholamines; Child; Cohort S | 2009 |
42 other studies available for normetanephrine and Sensitivity and Specificity
| Article | Year |
|---|---|
Updated reference intervals for urine normetanephrine have no effect on test sensitivity but fewer false positives.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; False Positive Reactions; Female; Humans; Male; Mi | 2022 |
ProSAAS peptide of the granin protein family in biochemical diagnostics of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Chromogranin A; Chromogranins; Female; Humans; Male; Metanephrine; Normetan | 2022 |
Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Humans; Inpatients; Metanephrine; Normetanephrine; Outpatients; Paraganglio | 2022 |
Clinical factors affecting spot urine fractionated metanephrines in patients suspected pheochromocytoma/paraganglioma.
Topics: Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aged, 80 and over; Female; Humans; Male; Metaneph | 2020 |
Evaluation of an ELISA for metanephrines in feline urine.
Topics: Animals; Cat Diseases; Cats; Enzyme-Linked Immunosorbent Assay; Female; Male; Metanephrine; Normetan | 2018 |
The role of urinary fractionated metanephrines in the diagnosis of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Female; Humans; Immunoenzyme Techniques; Male; Metanephrine; Middle | 2013 |
Phasing-in plasma metanephrines determination.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatograp | 2013 |
Comparison of plasma free metanephrines between healthy dogs and 3 dogs with pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Animals; Biomarkers, Tumor; Blood Chemical Analysis; Case-Control Studies; | 2013 |
Clinical utility of chromogranin A in SDHx-related paragangliomas.
Topics: Adult; Aged; Biomarkers; Child; Child, Preschool; Chromogranin A; Head and Neck Neoplasms; Humans; M | 2014 |
Plasma free metanephrines in the diagnosis of pheochromocytoma: diagnostic accuracy and strategies for Japanese patients.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adult; Biomarkers; Cohort Studies; Female; Hospitals, Munic | 2014 |
Amoxicillin-associated interference in an HPLC-EC assay for urinary fractionated metanephrines: potential pitfall in pheochromocytoma biochemical diagnosis.
Topics: Adolescent; Adrenal Gland Neoplasms; Amoxicillin; Child; Chromatography, High Pressure Liquid; Femal | 2014 |
[Analysis of laboratory data of 155 patients with pheochromocytoma-paraganglioma syndrome diagnosed during the past 20 years].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Biomarkers; Catecholamines; Child; Chromatography, | 2015 |
Symptom-dependent cut-offs of urine metanephrines improve diagnostic accuracy for detecting pheochromocytomas in two separate cohorts, compared to symptom-independent cut-offs.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Female; Humans; Male; Metanephrine; Middle Aged | 2016 |
Diethylation labeling combined with UPLC/MS/MS for simultaneous determination of a panel of monoamine neurotransmitters in rat prefrontal cortex microdialysates.
Topics: Amination; Animals; Biogenic Monoamines; Chromatography, Liquid; Dopamine; Neurotransmitter Agents; | 2008 |
Sensitive profiling of biogenic amines in urine using CE with transient isotachophoretic preconcentration.
Topics: Adult; Biogenic Amines; Dopamine; Electrophoresis; Electrophoresis, Capillary; Epinephrine; Humans; | 2009 |
Diagnostic accuracy of free and total metanephrines in plasma and fractionated metanephrines in urine of patients with pheochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Child; Femal | 2010 |
Is there still a place for adrenal venous sampling in the diagnostic localization of pheochromocytoma?
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Biomarkers, Tumor; Catecholamines; Female; H | 2011 |
Enzyme-linked immunoassay for plasma-free metanephrines in the biochemical diagnosis of phaeochromocytoma in adults is not ideal.
Topics: Adrenal Gland Neoplasms; Diagnostic Errors; Humans; Immunoenzyme Techniques; Metanephrine; Normetane | 2011 |
Plasma and urinary metanephrines determined by an enzyme immunoassay, but not serum chromogranin A for the diagnosis of pheochromocytoma in patients with adrenal mass.
Topics: Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adult; Aldosterone; Chromogranin A; Diagnosis, Diff | 2012 |
Different diagnostic cut-off values of urinary fractionated metanephrines according to sex for the diagnosis of pheochromocytoma in Korean subjects.
Topics: Academic Medical Centers; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Chromatography, High | 2012 |
Reference intervals for plasma free metanephrines with an age adjustment for normetanephrine for optimized laboratory testing of phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aged, 80 and over; Case-Control Studi | 2013 |
[Diagnosis of pheochromocytoma and paraganglioma: the clonidine suppression test in patients with borderline elevations of plasma free normetanephrine].
Topics: Adrenal Gland Neoplasms; Adult; Aged; Biomarkers; Clonidine; Female; Humans; Male; Middle Aged; Norm | 2013 |
Pheochromocytoma: a disease with many faces.
Topics: Adrenal Gland Neoplasms; Catecholamines; Chromatography, High Pressure Liquid; Clonidine; Diagnosis, | 2002 |
Comparative values of catecholamines and metabolites for the diagnosis of neuroblastoma.
Topics: Adrenal Gland Neoplasms; Catecholamines; Chromatography, High Pressure Liquid; Homovanillic Acid; Hu | 2003 |
Measurement of plasma free metanephrine and normetanephrine by liquid chromatography-tandem mass spectrometry for diagnosis of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Calibration; Chromatography, Liquid; Humans; Mass Spectrometry | 2004 |
Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines.
Topics: Adrenal Gland Neoplasms; Catecholamines; Humans; Metanephrine; Normetanephrine; Phenotype; Pheochrom | 2005 |
The role of chromogranin A in the management of patients with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Area Under Curve; Biomarkers, Tumor; Case-Control Studies; Cat | 2006 |
The diagnostic efficacy of urinary fractionated metanephrines measured by tandem mass spectrometry in detection of pheochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Child; Femal | 2007 |
Quantification of urinary catecholamines, their abundant metabolites, and 5-hydroxyindoleacetic acid by high performance liquid chromatography and electrochemical detection, using a single mobile phase and uniform isocratic conditions.
Topics: Catecholamines; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Homovanillic Acid; | 1994 |
Overnight excretion of urinary catecholamines and metabolites in the detection of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Chromatograp | 1996 |
Evaluation of urinary metanephrine and normetanephrine enzyme immunoassay (ELISA) kits by comparison with isotope dilution mass spectrometry.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Child; Child, Preschool; Enzyme-Linked Immunosorbent Ass | 1997 |
Determination of catecholamines and methoxycatecholamines excretion patterns in pig and rat urine by ion-exchange liquid chromatography with electrochemical detection.
Topics: Animals; Catecholamines; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Circadi | 1997 |
Efficacy of single-voided urine metanephrine and normetanephrine assay for diagnosing pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Biomarkers, Tumor; Female; Humans; Male; Metanephrine; Normetanephri | 1998 |
Simultaneous automatic determination of catecholamines and their 3-O-methyl metabolites in rat plasma by high-performance liquid chromatography using peroxyoxalate chemiluminescence reaction.
Topics: Animals; Blood Chemical Analysis; Catecholamines; Chromatography, High Pressure Liquid; Fluorescent | 1999 |
Plasma normetanephrine and metanephrine for detecting pheochromocytoma in von Hippel-Lindau disease and multiple endocrine neoplasia type 2.
Topics: Adolescent; Adult; Aged; Epinephrine; Female; Humans; Male; Metanephrine; Middle Aged; Multiple Endo | 1999 |
High-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometric method for the analysis of catecholamines and metanephrines in human urine.
Topics: Atmospheric Pressure; Buffers; Catecholamines; Chromatography, High Pressure Liquid; Chromatography, | 2000 |
Evaluation of specific high-performance liquid-chromatographic determinations of urinary adrenaline and noradrenaline by comparison with isotope dilution mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Creatinine; Dopamine; Electrochemistry; Epinephrine; Female; G | 2001 |
A "pheo" lurks: novel approaches for locating occult pheochromocytoma.
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Adrenalectomy; Carrier Proteins; Dopamine; Epinephri | 2001 |
Evaluation of specific high-performance liquid-chromatographic determinations of urinary metanephrine and normetanephrine by comparison with isotope dilution mass spectrometry.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Chromatography, High Pressure Liquid; Dopamine; Electrochemist | 2001 |
Validation of liquid chromatography-tandem mass spectrometry method for analysis of urinary conjugated metanephrine and normetanephrine for screening of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Biomarkers; Calibration; Chromatography, High Pressure Liquid; Colorimetry; | 2002 |
Methylated catecholamine metabolites for diagnosis of neuroblastoma.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Dopamine; Epinephrine; Female; Homovanill | 1992 |
Development and validation of a fluoroimmunoassay for urinary normetanephrine.
Topics: Animals; Cross Reactions; Fluorescein; Fluoresceins; Fluoroimmunoassay; Humans; Immunoglobulin G; No | 1991 |