acetaldehyde has been researched along with Sensitivity and Specificity in 44 studies
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.
acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Excerpt | Relevance | Reference |
---|---|---|
"Inhaled acetaldehyde may induce bronchoconstriction in asthmatic subjects and provides a new method to investigate airway responsiveness." | 7.70 | Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis. ( Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F, 2000) |
"Alcohol abuse has been shown to result in the production of antibodies against acetaldehyde-modified epitopes in proteins." | 3.73 | IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers. ( Anttila, P; Hietala, J; Koivisto, H; Latvala, J; Niemelä, O, 2006) |
"The present study examined whether measurement of hemoglobin-acetaldehyde (HbA1-AcH) using an improved methodology may be useful as a biological marker of alcohol abuse." | 3.70 | Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: effects of gender and hemoglobin concentration. ( Androulakakis, V; Brown, WJ; Hazelett, SE; Jarjoura, D; Liebelt, RA; Truitt, EB, 1998) |
"Inhaled acetaldehyde may induce bronchoconstriction in asthmatic subjects and provides a new method to investigate airway responsiveness." | 3.70 | Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis. ( Marín, J; Millan, M; Pérez, JA; Peris, R; Prieto, L; Sánchez-Toril, F, 2000) |
"Combination with the lung injury prediction score increased the AUC to 0." | 1.40 | Exhaled breath metabolomics as a noninvasive diagnostic tool for acute respiratory distress syndrome. ( Bos, LD; Knobel, HH; Nijsen, TM; Schultz, MJ; Sterk, PJ; Vink, TJ; Wang, Y; Weda, H; Zwinderman, AH, 2014) |
"Metaldehyde was headspace-extracted on a polydimethylsiloxane (PDMS) fiber at 70 degrees C for 25 min, desorbed, and analyzed rapidly by GC-MS." | 1.35 | Determination of metaldehyde in human serum by headspace solid-phase microextraction and gas chromatography-mass spectrometry. ( Akieda, K; Inokuchi, S; Morita, S; Motojyuku, M; Otsuka, H; Saito, T; Yamamoto, I, 2008) |
"Alcohol abuse has been shown to result in the production of antibodies against acetaldehyde-modified epitopes in proteins." | 1.33 | IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers. ( Anttila, P; Hietala, J; Koivisto, H; Latvala, J; Niemelä, O, 2006) |
"Acetaldehyde is a local carcinogen in the digestive tract in humans." | 1.31 | Ethanol-derived microbial production of carcinogenic acetaldehyde in achlorhydric atrophic gastritis. ( Färkkilä, M; Jousimies-Somer, H; Mentula, S; Nuutinen, H; Salaspuro, M; Salmela, KS; Väkeväinen, S, 2002) |
"Acetaldehyde was derivatized to 2,4-dinitrophenylhydrazone, which was determined by gas chromatography with electron-capture detection." | 1.30 | Determination of acetaldehyde in biological samples by gas chromatography with electron-capture detection. ( Ohata, H; Ohmori, S; Otsuka, M, 1997) |
"Phenobarbital pretreatment of the rats did not affect any of these kinetic parameters." | 1.28 | Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992) |
" The enzymes involved in the toxic metabolic pathway have been investigated in this study." | 1.28 | Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.27) | 18.7374 |
1990's | 10 (22.73) | 18.2507 |
2000's | 24 (54.55) | 29.6817 |
2010's | 9 (20.45) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Iitani, K | 1 |
Chien, PJ | 1 |
Suzuki, T | 2 |
Toma, K | 1 |
Arakawa, T | 1 |
Iwasaki, Y | 1 |
Mitsubayashi, K | 2 |
Szpot, P | 1 |
Buszewicz, G | 1 |
Jurek, T | 1 |
Teresiński, G | 1 |
Bos, LD | 1 |
Weda, H | 1 |
Wang, Y | 1 |
Knobel, HH | 1 |
Nijsen, TM | 1 |
Vink, TJ | 1 |
Zwinderman, AH | 1 |
Sterk, PJ | 1 |
Schultz, MJ | 1 |
Navaneethan, U | 1 |
Parsi, MA | 1 |
Gutierrez, NG | 1 |
Bhatt, A | 1 |
Venkatesh, PG | 1 |
Lourdusamy, D | 1 |
Grove, D | 1 |
Hammel, JP | 1 |
Jang, S | 1 |
Sanaka, MR | 1 |
Stevens, T | 1 |
Vargo, JJ | 1 |
Dweik, RA | 1 |
Schumer, EM | 1 |
Trivedi, JR | 1 |
van Berkel, V | 1 |
Black, MC | 1 |
Li, M | 1 |
Fu, XA | 1 |
Bousamra, M | 1 |
Shimomoto, T | 1 |
Collins, LB | 1 |
Yi, X | 1 |
Holley, DW | 1 |
Zhang, Z | 1 |
Tian, X | 1 |
Uchida, K | 1 |
Wang, C | 1 |
Hörkkö, S | 1 |
Willis, MS | 1 |
Gold, A | 1 |
Bultman, SJ | 1 |
Nakamura, J | 1 |
Speit, G | 1 |
Fröhler-Keller, M | 1 |
Schütz, P | 1 |
Neuss, S | 1 |
Saito, T | 1 |
Morita, S | 1 |
Motojyuku, M | 1 |
Akieda, K | 1 |
Otsuka, H | 1 |
Yamamoto, I | 1 |
Inokuchi, S | 1 |
Pontes, H | 1 |
Guedes de Pinho, P | 1 |
Casal, S | 1 |
Carmo, H | 1 |
Santos, A | 1 |
Magalhães, T | 1 |
Remião, F | 1 |
Carvalho, F | 1 |
Lourdes Bastos, M | 1 |
Dossi, N | 1 |
Susmel, S | 1 |
Toniolo, R | 1 |
Pizzariello, A | 1 |
Bontempelli, G | 1 |
Gonçalves, LM | 1 |
Magalhães, PJ | 1 |
Valente, IM | 1 |
Pacheco, JG | 1 |
Dostálek, P | 1 |
Sýkora, D | 1 |
Rodrigues, JA | 1 |
Barros, AA | 1 |
Toennes, SW | 1 |
Wagner, MG | 1 |
Kauert, GF | 1 |
Serrano, M | 1 |
Silva, M | 1 |
Gallego, M | 1 |
Väkeväinen, S | 1 |
Mentula, S | 1 |
Nuutinen, H | 1 |
Salmela, KS | 1 |
Jousimies-Somer, H | 1 |
Färkkilä, M | 1 |
Salaspuro, M | 1 |
Ukeda, H | 1 |
Shimamura, T | 1 |
Tsubouchi, M | 1 |
Harada, Y | 1 |
Nakai, Y | 1 |
Sawamura, M | 1 |
Diskin, AM | 1 |
Spanel, P | 1 |
Smith, D | 1 |
Willson, K | 1 |
Francis, DP | 1 |
Sparidans, RW | 2 |
Crommentuyn, KM | 1 |
Schellens, JH | 1 |
Beijnen, JH | 2 |
Warneke, C | 1 |
Rosén, S | 1 |
Lovejoy, ER | 1 |
de Gouw, JA | 1 |
Fall, R | 1 |
Peinado, RA | 1 |
Moreno, JA | 1 |
Muñoz, D | 1 |
Medina, M | 1 |
Moreno, J | 1 |
Matsunaga, H | 1 |
Nishio, G | 1 |
Toda, S | 1 |
Nakanishi, Y | 1 |
Li, J | 1 |
Yan, Q | 1 |
Gao, Y | 1 |
Ju, H | 1 |
Hietala, J | 1 |
Koivisto, H | 1 |
Latvala, J | 1 |
Anttila, P | 1 |
Niemelä, O | 1 |
Saito, Y | 1 |
Ueta, I | 1 |
Ogawa, M | 1 |
Hayashida, M | 1 |
Jinno, K | 1 |
Zimatkin, SM | 1 |
Buben, AL | 1 |
Ghica, ME | 1 |
Pauliukaite, R | 1 |
Marchand, N | 1 |
Devic, E | 1 |
Brett, CM | 1 |
Gallagher, D | 1 |
Cuppett, J | 1 |
Linssen, J | 1 |
Reitsma, H | 1 |
Cozijnsen, J | 1 |
Jones, AW | 1 |
Ohata, H | 1 |
Otsuka, M | 1 |
Ohmori, S | 1 |
Ferreiro, JA | 1 |
Consuegra, S | 1 |
Sierra, LM | 1 |
Comendador, MA | 1 |
Koskinen, LK | 1 |
Korpela, MM | 1 |
Lahtela, JT | 1 |
Laippala, PJ | 1 |
Pikkarainen, PH | 1 |
Koivula, TA | 1 |
Kawamoto, Y | 1 |
Shinozuka, K | 1 |
Kunitomo, M | 1 |
Haginaka, J | 1 |
Tottmar, O | 1 |
Marchner, H | 1 |
Pettersson, H | 1 |
Binding, N | 1 |
Schilder, K | 1 |
Czeschinski, PA | 1 |
Witting, U | 1 |
Hazelett, SE | 1 |
Liebelt, RA | 1 |
Brown, WJ | 1 |
Androulakakis, V | 1 |
Jarjoura, D | 1 |
Truitt, EB | 1 |
Veldkamp, A | 1 |
Hoetelmans, RM | 1 |
Sánchez-Toril, F | 1 |
Prieto, L | 1 |
Peris, R | 1 |
Pérez, JA | 1 |
Millan, M | 1 |
Marín, J | 1 |
Kiba, N | 1 |
Yagi, R | 1 |
Sun, L | 1 |
Tachibana, M | 1 |
Tani, K | 1 |
Koizumi, H | 1 |
Markowski, T | 1 |
Arciuch, LP | 1 |
Zwierz, K | 1 |
Bakush, AA | 1 |
Iwamoto, H | 1 |
Motomiya, Y | 1 |
Miura, K | 1 |
Morisawa, M | 1 |
Yoshimura, Y | 1 |
Maruyama, I | 1 |
Zuba, D | 1 |
Parczewski, A | 1 |
Reichenbächer, M | 1 |
Kiernan, UA | 1 |
Black, JA | 1 |
Williams, P | 1 |
Nelson, RW | 1 |
Kaminsky, LS | 1 |
Fraser, JM | 1 |
Seaman, M | 1 |
Dunbar, D | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Bile and Bile Duct/Pancreatic Duct Brushings Database for Patients With Pancreato-biliary Stricture[NCT01565460] | 200 participants (Actual) | Observational | 2012-02-29 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for acetaldehyde and Sensitivity and Specificity
Article | Year |
---|---|
Measuring and reporting the concentration of acetaldehyde in human breath.
Topics: Acetaldehyde; Alcoholic Intoxication; Alcoholism; Breath Tests; Ethanol; Humans; Predictive Value of | 1995 |
[Laboratory diagnosis of ethyl alcohol dependence syndrome].
Topics: Acetaldehyde; Alcoholism; beta-N-Acetylhexosaminidases; Biomarkers; Humans; Liver Function Tests; Se | 2001 |
2 trials available for acetaldehyde and Sensitivity and Specificity
Article | Year |
---|---|
Bioelectronic sniffers for ethanol and acetaldehyde in breath air after drinking.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Biosensing T | 2005 |
Effect of acetaldehyde and acetylsalicylic acid on HbA1c chromatography in the FPLC method with Mono S cation exchanger.
Topics: Acetaldehyde; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cation Exchange Resins; Chrom | 1998 |
40 other studies available for acetaldehyde and Sensitivity and Specificity
Article | Year |
---|---|
Fiber-Optic Bio-sniffer (Biochemical Gas Sensor) Using Reverse Reaction of Alcohol Dehydrogenase for Exhaled Acetaldehyde.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Biosensing Techniques; Breath Tests; Enzymes, | 2018 |
Fragmentation patterns involving ammonium adduct fragment ions: A comparison of the determination of metaldehyde in human blood by HPLC-QqQ-MS/MS and UHPLC-Q-TOF-MS.
Topics: Acetaldehyde; Adult; Ammonium Compounds; Chromatography, High Pressure Liquid; Female; Humans; Linea | 2018 |
Exhaled breath metabolomics as a noninvasive diagnostic tool for acute respiratory distress syndrome.
Topics: Acetaldehyde; Adult; Aged; Algorithms; Area Under Curve; Breath Tests; Critical Care; Exhalation; Fe | 2014 |
Volatile organic compounds in bile can diagnose malignant biliary strictures in the setting of pancreatic cancer: a preliminary observation.
Topics: Acetaldehyde; Acetone; Benzene; Bile; Biliary Tract Diseases; Carbon Disulfide; Case-Control Studies | 2014 |
High sensitivity for lung cancer detection using analysis of exhaled carbonyl compounds.
Topics: Acetaldehyde; Acetoin; Aged; Aldehydes; Biomarkers, Tumor; Breath Tests; Butanones; Case-Control Stu | 2015 |
A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity.
Topics: Acetaldehyde; Animals; Autoantibodies; Enzyme-Linked Immunosorbent Assay; Female; Magnetic Resonance | 2017 |
Low sensitivity of the comet assay to detect acetaldehyde-induced genotoxicity.
Topics: Acetaldehyde; Animals; Cells, Cultured; CHO Cells; Comet Assay; Cricetinae; Cricetulus; Cross-Linkin | 2008 |
Determination of metaldehyde in human serum by headspace solid-phase microextraction and gas chromatography-mass spectrometry.
Topics: Acetaldehyde; Dimethylpolysiloxanes; Drug Stability; Female; Gas Chromatography-Mass Spectrometry; H | 2008 |
GC determination of acetone, acetaldehyde, ethanol, and methanol in biological matrices and cell culture.
Topics: Acetaldehyde; Body Fluids; Cell Culture Techniques; Chlorobutanol; Chromatography, Gas; Culture Medi | 2009 |
Application of microchip electrophoresis with electrochemical detection to environmental aldehyde monitoring.
Topics: Acetaldehyde; Acrolein; Aldehydes; Atmosphere; Electrochemistry; Electrophoresis, Microchip; Environ | 2009 |
Analysis of aldehydes in beer by gas-diffusion microextraction: characterization by high-performance liquid chromatography-diode-array detection-atmospheric pressure chemical ionization-mass spectrometry.
Topics: Acetaldehyde; Aldehydes; Beer; Chemical Fractionation; Chromatography, High Pressure Liquid; Furalde | 2010 |
Application of LC-TOF MS to analysis of hemoglobin acetaldehyde adducts in alcohol detoxification patients.
Topics: Acetaldehyde; Adult; Aged; Alcoholism; Amino Acid Sequence; Child; Child, Preschool; Chromatography, | 2010 |
Micro liquid-liquid extraction combined with large-volume injection gas chromatography-mass spectrometry for the determination of haloacetaldehydes in treated water.
Topics: Acetaldehyde; Acetates; Chloral Hydrate; Gas Chromatography-Mass Spectrometry; Halogenation; Hydroge | 2011 |
Ethanol-derived microbial production of carcinogenic acetaldehyde in achlorhydric atrophic gastritis.
Topics: Acetaldehyde; Achlorhydria; Adult; Case-Control Studies; Ethanol; Female; Gastric Juice; Gastric Muc | 2002 |
Spectrophotometric assay of superoxide anion formed in Maillard reaction based on highly water-soluble tetrazolium salt.
Topics: Acetaldehyde; Cytochrome c Group; Glyceraldehyde; Lysine; Maillard Reaction; Sensitivity and Specifi | 2002 |
Time variation of ammonia, acetone, isoprene and ethanol in breath: a quantitative SIFT-MS study over 30 days.
Topics: Acetaldehyde; Acetone; Adult; Aged; Air; Ammonia; Breath Tests; Butadienes; Ethanol; Female; Hemiter | 2003 |
A direct analytical demonstration of the essential equivalence of detrended fluctuation analysis and spectral analysis of RR interval variability.
Topics: Acetaldehyde; Acetone; Adult; Aged; Ammonia; Breath Tests; Butadienes; Ethanol; Female; Hemiterpenes | 2003 |
Liquid chromatographic assay for the antiviral nucleotide analogue tenofovir in plasma using derivatization with chloroacetaldehyde.
Topics: Acetaldehyde; Adenine; Chromatography, Liquid; HIV Infections; Humans; Organophosphonates; Organopho | 2003 |
Two additional advantages of proton-transfer ion trap mass spectrometry.
Topics: Acetaldehyde; Acetone; Benzene; Ethanol; Ions; Mass Spectrometry; Organic Chemicals; Protons; Qualit | 2004 |
Gas chromatographic quantification of major volatile compounds and polyols in wine by direct injection.
Topics: Acetaldehyde; Alcohols; Chromatography, Gas; Polymers; Sensitivity and Specificity; Volatilization; | 2004 |
Electrogenerated chemiluminescence detection of amino acids based on precolumn derivatization coupled with capillary electrophoresis separation.
Topics: 2,2'-Dipyridyl; Acetaldehyde; Amino Acids; Coordination Complexes; Electrophoresis, Capillary; Hydro | 2006 |
IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers.
Topics: Acetaldehyde; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Central Nervous System Depressants; C | 2006 |
Miniaturized sample preparation needle: a versatile design for the rapid analysis of smoking-related compounds in hair and air samples.
Topics: Acetaldehyde; Breath Tests; Chromatography, Gas; Environmental Exposure; Equipment Design; Formaldeh | 2007 |
A novel method for evaluation of ethanol oxidation in living brain.
Topics: Acetaldehyde; Animals; Brain; Chromatography, Gas; Ethanol; Evaluation Studies as Topic; Injections, | 2006 |
An improved biosensor for acetaldehyde determination using a bienzymatic strategy at poly(neutral red) modified carbon film electrodes.
Topics: Acetaldehyde; Aldehyde Oxidoreductases; Biosensing Techniques; Carbon; Coloring Agents; Cross-Linkin | 2007 |
Evaluation of threshold limit methods for sensory data.
Topics: Acetaldehyde; Copper; Data Interpretation, Statistical; Environmental Monitoring; Evaluation Studies | 2007 |
Static headspace gas chromatography of acetaldehyde in aqueous foods and polythene terephthalate.
Topics: Acetaldehyde; Beverages; Chromatography, Gas; Food Analysis; Food Packaging; Polyethylene Terephthal | 1995 |
Determination of acetaldehyde in biological samples by gas chromatography with electron-capture detection.
Topics: Acetaldehyde; Animals; Chromatography, Gas; Ethanol; Glucose; Humans; Hydrazones; Liver; Male; Rats; | 1997 |
Is the white-ivory assay of Drosophila melanogaster a useful tool in genetic toxicology?
Topics: Acetaldehyde; Animals; Antimetabolites; Cross-Linking Reagents; DNA Adducts; DNA Damage; Drosophila | 1997 |
Determination of ATP and its metabolites released from rat caudal artery by isocratic ion-pair reversed-phase high-performance liquid chromatography.
Topics: Acetaldehyde; Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arteries; Calibration | 1998 |
Determination of acetaldehyde in rat blood by the use of rat liver aldehyde dehydrogenase.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Ethanol; Mitochondria, Liver; Rats; Rats, Sprague-Daw | 1978 |
Simultaneous determination of airborne acetaldehyde, acetone, 2-butanone, and cyclohexanone using sampling tubes with 2,4-dinitrophenylhydrazine-coated solid sorbent.
Topics: Acetaldehyde; Air Pollutants; Butanones; Calibration; Chromatography, High Pressure Liquid; Cyclohex | 1998 |
Evaluation of acetaldehyde-modified hemoglobin and other markers of chronic heavy alcohol use: effects of gender and hemoglobin concentration.
Topics: Acetaldehyde; Adult; Alcoholism; Biomarkers; Female; Glycated Hemoglobin; Hemoglobinometry; Hemoglob | 1998 |
Improved and simplified liquid chromatographic assay for adefovir, a novel antiviral drug, in human plasma using derivatization with chloroacetaldehyde.
Topics: Acetaldehyde; Adenine; Antiviral Agents; Chemical Precipitation; Chromatography, Liquid; Drug Stabil | 1999 |
Differences in airway responsiveness to acetaldehyde and methacholine in asthma and chronic bronchitis.
Topics: Acetaldehyde; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bro | 2000 |
Poly(allylamine) beads as selective sorbent for preconcentration of formaldehyde and acetaldehyde in high-performance liquid chromatographic analysis.
Topics: Acetaldehyde; Adsorption; Allylamine; Chromatography, High Pressure Liquid; Formaldehyde; Gas Chroma | 2000 |
Immunochemical assay of hemoglobin with N(epsilon)-(carboxymethyl)lysine at lysine 66 of the beta chain.
Topics: Acetaldehyde; Adult; Aged; Antibodies, Monoclonal; Hemoglobins; Humans; Immunoassay; Lysine; Middle | 2001 |
Optimization of solid-phase microextraction conditions for gas chromatographic determination of ethanol and other volatile compounds in blood.
Topics: Acetaldehyde; Acetone; Alcohols; Chromatography, Gas; Ethanol; Reproducibility of Results; Sensitivi | 2002 |
High-throughput analysis of hemoglobin from neonates using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Acetaldehyde; Hemoglobins; Humans; Infant, Newborn; Neonatal Screening; Point Mutation; Reproducibil | 2002 |
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver In | 1992 |