A peptidyl-prolyl cis-trans isomerase FKBP14 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NWM8]
PPIase FKBP14;
EC 5.2.1.8;
22 kDa FK506-binding protein;
22 kDa FKBP;
FKBP-22;
FK506-binding protein 14;
FKBP-14;
Rotamase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cycloheximide | Homo sapiens (human) | Ki | 76.2000 | 1 | 1 |
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| peptidyl-prolyl cis-trans isomerase activity | molecular function | Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). [EC:5.2.1.8] |
| calcium ion binding | molecular function | Binding to a calcium ion (Ca2+). [GOC:ai] |
| protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
This protein is located in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| endoplasmic reticulum lumen | cellular component | The volume enclosed by the membranes of the endoplasmic reticulum. [ISBN:0198547684] |