A phosphatidylserine lipase ABHD16A that is encoded in the genome of human. [PRO:DNx, UniProtKB:O95870]
EC 3.1.-.-;
Alpha/beta hydrolase domain-containing protein 16A;
Abhydrolase domain-containing protein 16A;
HLA-B-associated transcript 5;
hBAT5;
Monoacylglycerol lipase ABHD16A;
3.1.1.23;
Protein G5
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 1,6-bis(cyclohexyloximinocarbonyl)hexane | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| orlistat | Homo sapiens (human) | IC50 | 0.1000 | 2 | 2 |
| palmostatin b | Homo sapiens (human) | IC50 | 0.0853 | 3 | 3 |
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| phospholipase activity | molecular function | Catalysis of the hydrolysis of a glycerophospholipid. [ISBN:0198506732] |
| protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
| acylglycerol lipase activity | molecular function | Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. [EC:3.1.1.23, MetaCyc:3.1.1.23-RXN] |
This protein is located in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
This protein is involved in 3 target(s):
| Target | Category | Definition |
|---|---|---|
| phosphatidylserine catabolic process | biological process | The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. [ISBN:0198506732] |
| monoacylglycerol catabolic process | biological process | The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. [PMID:25290914] |
| prostaglandin catabolic process | biological process | The chemical reactions and pathways resulting in the breakdown of prostaglandin. [GO_REF:0000068, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25290914] |