Page last updated: 2024-08-07 18:51:48

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9P032]

Synonyms

Hormone-regulated proliferation-associated protein of 20 kDa

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Compounds (2)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
auraptenHomo sapiens (human)IC5014.500022
marminHomo sapiens (human)IC5030.000022

Enables

This protein enables 2 target(s):

TargetCategoryDefinition
protein bindingmolecular functionBinding to a protein. [GOC:go_curators]
calmodulin bindingmolecular functionBinding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. [GOC:krc]

Located In

This protein is located in 4 target(s):

TargetCategoryDefinition
mitochondrioncellular componentA semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]
mitochondrial inner membranecellular componentThe inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. [GOC:ai]
cytosolcellular componentThe part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
mitochondrial membranecellular componentEither of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. [GOC:mah, NIF_Subcellular:sao1045389829]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
mitochondrioncellular componentA semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. [GOC:giardia, ISBN:0198506732]

Involved In

This protein is involved in 4 target(s):

TargetCategoryDefinition
positive regulation of cell population proliferationbiological processAny process that activates or increases the rate or extent of cell proliferation. [GOC:go_curators]
mitochondrial respiratory chain complex I assemblybiological processThe aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I. [GOC:rph]
negative regulation of apoptotic processbiological processAny process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
defense response to virusbiological processReactions triggered in response to the presence of a virus that act to protect the cell or organism. [GOC:ai]