| Assay ID | Title | Year | Journal | Article |
|---|
| AID1224766 | Delta TM value showing the stabilisation of CK1G3 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188263 | Inhibition of human AMPKalpha2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281607 | Inhibition of GSKbeta at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188304 | Cytotoxicity against human SNU484 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188289 | Inhibition of human SAPK3 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188297 | Inhibition of PKCK2alpha (unknown origin) overexpressed in TE2 cells assessed as inhibition of phosphorylation of GST-CS | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID360766 | Antiviral activity against Dengue virus infected in african green monkey Vero cells administered before viral challenge after 3 days by viral plaque assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Feb-27, Volume: 104, Issue:9
| c-Src protein kinase inhibitors block assembly and maturation of dengue virus. |
| AID1184252 | Anticancer activity against human MCF7 cells assessed as cell viability at 25 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1224785 | Delta TM value showing the stabilisation of PDK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224750 | Delta TM value showing the stabilisation of CAMK1G produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1396632 | Binding affinity to recombinant human CK2alpha/beta expressed in Escherichia coli by surface plasmon resonance analysis | 2018 | Bioorganic & medicinal chemistry, 08-07, Volume: 26, Issue:14
| Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors. |
| AID325716 | Inhibition of casein kinase 2 in rat liver | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188272 | Inhibition of human GSK3beta assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224802 | Delta TM value showing the stabilisation of TNIK produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188273 | Inhibition of human JNK1alpha1 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224805 | Delta TM value showing the stabilisation of VRK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224759 | Delta TM value showing the stabilisation of CDKL1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID393021 | Inhibition of human recombinant casein kinase 2 subunit alpha2beta2 expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scintillation counting | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4
| Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2. |
| AID1184253 | Anticancer activity against human MCF7 cells assessed as cell viability at 50 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID281619 | Inhibition of c-Fgr at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224798 | Delta TM value showing the stabilisation of DRAK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281622 | Inhibition of DYRK1A at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID435639 | Inhibition of Zea mays CK2alpha | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID1224801 | Delta TM value showing the stabilisation of MST1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188264 | Inhibition of human CDK2/cyclinA assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1808021 | Inhibition of porcine heart malate dehydrogenase assessed as reduction in enzyme inhibition at 3 times IC50 preincubated for 5 min followed by nicotinamide adenine dinucleotide addition and monitered for 90 sec in presence of 0.01% Triton-X100 by spectrop | 2021 | Journal of medicinal chemistry, 12-09, Volume: 64, Issue:23
| Colloidal Aggregators in Biochemical SARS-CoV-2 Repurposing Screens. |
| AID1188303 | Cytotoxicity against human NCI-N87 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224784 | Delta TM value showing the stabilisation of PCTK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1202638 | Inhibition of CK2 (unknown origin) | 2015 | European journal of medicinal chemistry, , Volume: 96 | Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening. |
| AID757709 | Inhibition of human recombinant CK2 expressed in Escherichia coli BL21(DE3) using RRRDDDSDDD as substrate after 15 mins by capillary electrophoretic analysis | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2. |
| AID573108 | Antiviral activity against Hepatitis C virus genotype 1b infected in human Huh5-2 cells assessed as reduction in replicon RNA after 4 days by luciferase assay | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID1188313 | Cytotoxicity against human TE2 cells expressing CK2 assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188281 | Inhibition of human PDK1 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188312 | Cytotoxicity against GFP-tagged human TE2 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224763 | Delta TM value showing the stabilisation of CLK3 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281598 | Inhibition of MAPKAPK2 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188300 | Cytotoxicity against human MKN28 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188286 | Inhibition of human ROCK2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1184262 | Anticancer activity against human CCRF-CEM cells assessed as cell viability at 100 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1188288 | Inhibition of human SAPK2b assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1184254 | Anticancer activity against human MCF7 cells assessed as cell viability at 100 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1224758 | Delta TM value showing the stabilisation of CDK6 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188291 | Inhibition of human SGK assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281594 | Inhibition of SAPK2b/p38--beta-2 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188310 | Cytotoxicity against human SNU761 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281609 | Inhibition of AMPK at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188293 | Inhibition of human CK2 assessed as residual activity by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224790 | Delta TM value showing the stabilisation of PLK4 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188294 | Competitive inhibition of human CK2 assessed as competitive with respect to ATP | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID435140 | Relative inhibition of I174A-mutated CK2 holoenzyme compared to wild-type | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID1188292 | Inhibition of human Syk assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224781 | Delta TM value showing the stabilisation of PAK4 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188275 | Inhibition of human Lck assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281602 | Inhibition of PKCalpha at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1184251 | Anticancer activity against human MCF7 cells assessed as cell viability at 12.5 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1224807 | Delta TM value showing the stabilisation of YSK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224786 | Delta TM value showing the stabilisation of PIM1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID325720 | Inhibition of NS3-associated HCV viral helicase activity using RNA substrate | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID325717 | Inhibition of casein kinase 2 in human liver | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1414005 | Inhibition of recombinant full length human His-tagged CK2alpha1 expressed in baculovirus expression system using ser/thr-11 peptide as substrate measured after 1 hr by Z'-Lyte assay | 2018 | MedChemComm, Sep-01, Volume: 9, Issue:9
| Design, synthesis, and evaluation of 4,5,6,7-tetrahydrobenzo[ |
| AID1167184 | Inhibition of human recombinant CK2a1/CK2b holoenzyme expressed in Escherichia coli BL21(DE3) at 10 uM pre-incubated for 10 mins before substrate addition by capillary electrophoresis based assay | 2015 | Journal of medicinal chemistry, Jan-08, Volume: 58, Issue:1
| Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2. |
| AID1224754 | Delta TM value showing the stabilisation of CAMK2G produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224783 | Delta TM value showing the stabilisation of PAK6 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1539763 | Inhibition of CK2alpha in human PLC1 cells using (Arg)3(Glu)3Thr(Glu)3 as substrate after 24 hrs in presence of [32P]gammaGTP | 2019 | European journal of medicinal chemistry, Nov-01, Volume: 181 | Small molecule modulators targeting protein kinase CK1 and CK2. |
| AID1188277 | Inhibition of human MAPK2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID435640 | Inhibition of wild-type CK2 holoenzyme | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID1224804 | Delta TM value showing the stabilisation of VRK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281597 | Inhibition of MAPKAPK1a at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID573105 | Cytotoxicity against human HuH6 cells after 3 days by MTT assay | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID1188276 | Inhibition of human Lyn assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224780 | Delta TM value showing the stabilisation of OSR1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281617 | Inhibition of Lck at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID281623 | Inhibition of PP2A at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID281608 | Inhibition of ROCK2 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224769 | Delta TM value showing the stabilisation of GSK3B produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224803 | Delta TM value showing the stabilisation of PBK produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281612 | Inhibition of CK2 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188308 | Cytotoxicity against human SKHEP1 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188283 | Inhibition of human PKBalpha assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224778 | Delta TM value showing the stabilisation of NEK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188290 | Inhibition of human SAPK4 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID436039 | Inhibition of I174A-mutated CK2 holoenzyme | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID325719 | Inhibition of NS3-associated HCV helicase activity using DNA substrate | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281634 | Selectivity index, ratio of IC50 for CK2 to IC50 for MKK | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224768 | Delta TM value showing the stabilisation of DMPK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188268 | Inhibition of human CSK assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224762 | Delta TM value showing the stabilisation of CLK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188279 | Inhibition of human MAPKAP-K3 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188307 | Cytotoxicity against human Hep3B cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281589 | Inhibition of cell viability in Jurkat T cells after 24 hrs by MTT method | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188262 | Inhibition of human AMPKalpha1 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224782 | Delta TM value showing the stabilisation of PAK5 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224777 | Delta TM value showing the stabilisation of MST4(1) produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281621 | Inhibition of CSK at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID281595 | Inhibition of SAPK3/p38gamma relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224757 | Delta TM value showing the stabilisation of CDK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281616 | Inhibition of PiD261 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224791 | Delta TM value showing the stabilisation of PRKACA produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188270 | Inhibition of human Fgr assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281631 | Inhibition of SAPK2a/p38 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID281611 | Inhibition of at Phospholipase at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224806 | Delta TM value showing the stabilisation of VRK3 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID435763 | Inhibitory constant against Zea mays CK2alpha | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID281614 | Inhibition of CK1 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224752 | Delta TM value showing the stabilisation of CAMK2B produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1184261 | Anticancer activity against human CCRF-CEM cells assessed as cell viability at 50 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1224772 | Delta TM value showing the stabilisation of MAP2K6 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188301 | Cytotoxicity against human MKN45 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281630 | Inhibition of JNK/SAPK1c at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224771 | Delta TM value showing the stabilisation of MEK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID573112 | Cytotoxicity against human Huh5-2 cells after 3 days by MTT assay | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID360767 | Antiviral activity against Dengue virus infected in african green monkey Vero cells administered after viral challenge after 3 days by viral plaque assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Feb-27, Volume: 104, Issue:9
| c-Src protein kinase inhibitors block assembly and maturation of dengue virus. |
| AID573111 | Antiviral activity against Hepatitis C virus genotype 1b infected in human Huh-Mono cells assessed as reduction in replicon RNA after 4 days by RT-qPCR analysis | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID1224764 | Delta TM value showing the stabilisation of CK1G1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224756 | Delta TM value showing the stabilisation of CAMKK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1167185 | Inhibition of human recombinant CK2a1/CK2b holoenzyme expressed in Escherichia coli BL21(DE3) pre-incubated for 10 mins before substrate addition by capillary electrophoresis based assay | 2015 | Journal of medicinal chemistry, Jan-08, Volume: 58, Issue:1
| Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2. |
| AID1915547 | Inhibition of human recombinant GST-tagged CK-2 using RRRADDSDDDDD as substrate incubated for 5 mins by scintillation counter analysis | 2021 | European journal of medicinal chemistry, Jan-01, Volume: 209 | Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors. |
| AID281601 | Inhibition of PKA at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224760 | Delta TM value showing the stabilisation of CHEK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188305 | Cytotoxicity against human SNU668 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188284 | Inhibition of human PKCalpha assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188267 | Inhibition of human CK2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224751 | Delta TM value showing the stabilisation of CAMK2A produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1184259 | Anticancer activity against human CCRF-CEM cells assessed as cell viability at 12.5 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1184248 | Inhibition of human CK2alpha using RRRDDDSDDD peptide substrate by P81 filter-binding assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1224789 | Delta TM value showing the stabilisation of PLK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224800 | Delta TM value showing the stabilisation of MST4 (2) produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281593 | Inhibition of MAPK2/ERK2 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID573109 | Antiviral activity against Hepatitis C virus genotype 1b infected in human Huh-9-13 cells assessed as reduction in replicon RNA after 4days by RT-qPCR analysis | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID650667 | Inhibition of calf thymus casein kinase-2 using casein as substrate after 15 mins by liquid scintillation counting | 2012 | Bioorganic & medicinal chemistry, Apr-01, Volume: 20, Issue:7
| Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors. |
| AID281620 | Inhibition of Syk at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID281596 | Inhibition of SAPK4/p38delta at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188298 | Cytotoxicity against human AGS cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224792 | Delta TM value showing the stabilisation of RIOK2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID757712 | Inhibition of human recombinant CK2 expressed in Escherichia coli BL21(DE3) using RRRDDDSDDD as substrate at 10 uM after 15 mins by capillary electrophoretic analysis relative to control | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2. |
| AID1188265 | Inhibition of human CHK1 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224767 | Delta TM value showing the stabilisation of DAPK3 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188287 | Inhibition of human SAPK2a assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224775 | Delta TM value showing the stabilisation of ERK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224788 | Delta TM value showing the stabilisation of PIM3 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224799 | Delta TM value showing the stabilisation of NDR1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188299 | Cytotoxicity against human MKN1 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281605 | Inhibition of SGK at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID325722 | Inhibition of NS3-associated WNV helicase activity using RNA substrate | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224787 | Delta TM value showing the stabilisation of PIM2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID393020 | Inhibition of human recombinant casein kinase 2 subunit alpha expressed in Escherichia coli BL21 (DE3) assessed as [32P] incorporation by liquid scintillation counting | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4
| Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2. |
| AID1224765 | Delta TM value showing the stabilisation of CK1G2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1420033 | Inhibition of DYRK1A (unknown origin) | 2018 | Journal of medicinal chemistry, 11-21, Volume: 61, Issue:22
| Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics. |
| AID352795 | Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3) | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11
| Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid. |
| AID1224753 | Delta TM value showing the stabilisation of CAMK2D produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224795 | Delta TM value showing the stabilisation of SLK produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1184267 | Binding affinity to CK2alpha (unknown origin) | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID281610 | Inhibition of at CHK1 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224794 | Delta TM value showing the stabilisation of RSK2b produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224776 | Delta TM value showing the stabilisation of ERK3 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281604 | Inhibition of PKBalpha at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188280 | Inhibition of human MSK1 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281592 | Inhibition of MKK1 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188278 | Inhibition of human MAPKAP-K2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188309 | Cytotoxicity against human SNU73 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID281635 | Selectivity index, ratio of IC50 for CK2 to IC50 for MAPKAPK1a | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID281618 | Inhibition of Lyn at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1224797 | Delta TM value showing the stabilisation of MPSK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188296 | Inhibition of PKCK2alpha (unknown origin) overexpressed in TE2 cells assessed as inhibition of phosphorylation of GST-CS after 24 hrs by in vitro kinase assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224748 | Delta TM value showing the stabilisation of AMPKA2 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281600 | Inhibition of PRAK at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188306 | Cytotoxicity against human HepG2 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188266 | Inhibition of human CK1 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224749 | Delta TM value showing the stabilisation of CAMK1D produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID281603 | Inhibition of PDK1 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188311 | Cytotoxicity against human SNU878 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1808020 | Inhibition of porcine heart malate dehydrogenase preincubated for 5 min followed by nicotinamide adenine dinucleotide addition and monitered for 90 sec by spectrophotometric method | 2021 | Journal of medicinal chemistry, 12-09, Volume: 64, Issue:23
| Colloidal Aggregators in Biochemical SARS-CoV-2 Repurposing Screens. |
| AID1224796 | Delta TM value showing the stabilisation of LOK produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1184260 | Anticancer activity against human CCRF-CEM cells assessed as cell viability at 25 uM after 24 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties. |
| AID1188282 | Inhibition of human PKA assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1188271 | Inhibition of human GCK assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID435888 | Relative inhibition of V66A-mutated CK2 holoenzyme compared to wild-type | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID281606 | Inhibition of S6K1 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1915582 | Inhibition of CK2alpha (unknown origin) relative to control | 2021 | European journal of medicinal chemistry, Jan-01, Volume: 209 | Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors. |
| AID1224774 | Delta TM value showing the stabilisation of p38beta produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224779 | Delta TM value showing the stabilisation of NEK6 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID435764 | Inhibition of V66A-mutated CK2 holoenzyme | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID281615 | Inhibition of at GCK at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188285 | Inhibition of human PRAK assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID573110 | Antiviral activity against Hepatitis C virus genotype 1b infected in human HuH6 cells assessed as reduction in replicon RNA after 4days by RT-qPCR analysis | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID281613 | Inhibition of CDK2/Cyclin A at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID1188269 | Inhibition of human DYRK2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID573106 | Cytotoxicity against human Huh-9-13 cells after 3 days by MTT assay | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID1224761 | Delta TM value showing the stabilisation of CLK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224773 | Delta TM value showing the stabilisation of ASK1 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1224793 | Delta TM value showing the stabilisation of RSK2a produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1750468 | Inhibition of CK2 (unknown origin) | | | |
| AID281599 | Inhibition of MSK1 at 10 uM relative to control | 2004 | Journal of medicinal chemistry, Dec-02, Volume: 47, Issue:25
| Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole. |
| AID325718 | Inhibition of DYRK1a | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID573107 | Cytotoxicity against human Huh-Mono cells after 3 days by MTT assay | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9
| Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. |
| AID1224770 | Delta TM value showing the stabilisation of JAK1~B produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1808030 | Inhibition of SARS-COV2 N-terminal MBP-tagged 3CL protease using DABCYL-KTSAVLQSGFRKME-EDANS as substrate measured upto 30 mins by FRET assay | 2021 | Journal of medicinal chemistry, 12-09, Volume: 64, Issue:23
| Colloidal Aggregators in Biochemical SARS-CoV-2 Repurposing Screens. |
| AID240983 | Inhibitory concentration against hepatitis C virus helicase | 2005 | Journal of medicinal chemistry, Jan-13, Volume: 48, Issue:1
| Control of hepatitis C: a medicinal chemistry perspective. |
| AID325721 | Inhibition of NS3-associated WNV helicase activity using DNA substrate | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188274 | Inhibition of human JNK2alpha2 assessed as residual activity at 10 uM by KinaseProfiler assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1224755 | Delta TM value showing the stabilisation of CAMK4 produced by compound binding | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
| AID1188302 | Cytotoxicity against human MKN74 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Sep-01, Volume: 22, Issue:17
| Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID588378 | qHTS for Inhibitors of ATXN expression: Validation | | | |
| AID1347410 | qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library | 2019 | Cellular signalling, 08, Volume: 60 | A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening. |
| AID1347058 | CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1347405 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347050 | Natriuretic polypeptide receptor (hNpr2) antagonism - Pilot subtype selectivity assay | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID1347049 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot screen | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347045 | Natriuretic polypeptide receptor (hNpr1) antagonism - Pilot counterscreen GloSensor control cell line | 2019 | Science translational medicine, 07-10, Volume: 11, Issue:500
| Inhibition of natriuretic peptide receptor 1 reduces itch in mice. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347057 | CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID504836 | Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation | 2002 | The Journal of biological chemistry, Apr-19, Volume: 277, Issue:16
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. |
| AID1347151 | Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID588349 | qHTS for Inhibitors of ATXN expression: Validation of Cytotoxic Assay | | | |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347059 | CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation | 2019 | PloS one, , Volume: 14, Issue:7
| Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors. |
| AID1802603 | CK2α Inhibition Assay from Article 10.1016/j.bioorg.2017.02.017: \\Synthesis, in vitro antiproliferative activity and kinase profile of new benzimidazole and benzotriazole derivatives.\\ | 2017 | Bioorganic chemistry, 06, Volume: 72 | Synthesis, in vitro antiproliferative activity and kinase profile of new benzimidazole and benzotriazole derivatives. |
| AID1796664 | Kinase Inhibition Assay from Article 10.1042/BJ20030674: \\Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).\\ | 2003 | The Biochemical journal, Sep-15, Volume: 374, Issue:Pt 3
| Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). |
| AID1801064 | Fluorescence Titration Assay from Article 10.1021/bi500959t: \\Quinone reductase 2 is an adventitious target of protein kinase CK2 inhibitors TBBz (TBI) and DMAT.\\ | 2015 | Biochemistry, Jan-13, Volume: 54, Issue:1
| Quinone reductase 2 is an adventitious target of protein kinase CK2 inhibitors TBBz (TBI) and DMAT. |
| AID1801065 | Inhibition of Steady-State Catalysis Assay from Article 10.1021/bi500959t: \\Quinone reductase 2 is an adventitious target of protein kinase CK2 inhibitors TBBz (TBI) and DMAT.\\ | 2015 | Biochemistry, Jan-13, Volume: 54, Issue:1
| Quinone reductase 2 is an adventitious target of protein kinase CK2 inhibitors TBBz (TBI) and DMAT. |
| AID1811 | Experimentally measured binding affinity data derived from PDB | 2003 | European journal of biochemistry, Aug, Volume: 270, Issue:15
| Alternative binding modes of an inhibitor to two different kinases. |
| AID977608 | Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB | 2003 | European journal of biochemistry, Aug, Volume: 270, Issue:15
| Alternative binding modes of an inhibitor to two different kinases. |
| AID1803986 | 3CLpro enzyme assay from Article 10.1101/2020.07.17.207019: \\Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening.\\ | 2020 | bioRxiv : the preprint server for biology, Aug-11 | Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening. |
| AID1803987 | SARS-CoV-2 CPE assay from Article 10.1101/2020.07.17.207019: \\Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening.\\ | 2020 | bioRxiv : the preprint server for biology, Aug-11 | Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |