disperse blue 124 profile

Disperse Blue 124, also known as C.I. Disperse Blue 124, is a synthetic organic dye belonging to the anthraquinone class. Its synthesis typically involves a multi-step process starting with anthraquinone derivatives. Disperse Blue 124 finds application as a colorant in various industries, including textiles, plastics, and paints. Its vibrant blue color and good fastness properties make it a popular choice for dyeing synthetic fibers such as polyester. Studies on Disperse Blue 124 often focus on its impact on the environment, particularly its potential toxicity and bioaccumulation in aquatic ecosystems. The research aims to understand its fate and transport in water bodies, as well as its effects on aquatic organisms. Furthermore, research explores alternative and more sustainable dye options to minimize environmental pollution.'

Disperse Blue 124: RN given refers to cpd with unknown MF [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Disperse Blue 124 : A monoazo compound consisting of diazene with a 5-nitrothiazol-2-yl group attached to one nitrogen and a substituted 4-aminophenyl group attached to the other; used as a dye standard for the assay of allergy-releasing dyes in textiles. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	84802
CHEBI ID	59605
MeSH ID	M0189220

Synonym
c.i. disperse blue 124
disperse blue 124
2-(n-ethyl-4-((5-nitrothiazol-2-yl)azo)-m-toluidino)ethyl acetate
CHEBI:59605 ,
61951-51-7
2-(ethyl{3-methyl-4-[(5-nitro-1,3-thiazol-2-yl)diazenyl]phenyl}amino)ethyl acetate
2-[n-ethyl-3-methyl-4-[(5-nitro-1,3-thiazol-2-yl)diazenyl]anilino]ethyl acetate
einecs 239-203-6
15141-18-1
serisol 2rd
EPITOPE ID:131801
AKOS015902614
W-110405
2-[n-ethyl-4-[(5-nitrothiazol-2-yl)azo]-m-toluidino]ethyl acetate
Q27126800
disperse blue 124 100 microg/ml in acetonitrile
DTXSID40864562
ethanol, 2-[ethyl[3-methyl-4-[2-(5-nitro-2-thiazolyl)diazenyl]phenyl]amino]-, 1-acetate

Role	Description
dye	null
hapten	Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals.
allergen	A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
1,3-thiazoles
monoazo compound	Compounds containing single -N=N- group.
tertiary amine	A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	6 (24.00)	18.2507
2000's	9 (36.00)	29.6817
2010's	8 (32.00)	24.3611
2020's	2 (8.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (3.45%)	6.00%
Case Studies	14 (48.28%)	4.05%
Observational	0 (0.00%)	0.25%
Other	14 (48.28%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
2-nitropropane 2-nitropropane: RN given refers to cpd with locant for nitro moiety in 2 position. 2-nitropropane : A secondary nitroalkane that is propane in which a hydrogen at position 2 has been replaced by a nitro group. Mainly used as a solvent (b.p. 120degreeC).	2.1	1	secondary nitroalkane	carcinogenic agent; hepatotoxic agent; polar aprotic solvent; xenobiotic
formaldehyde paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy	2.06	1	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
diphenylpyraline diphenylpyraline: RN given refers to parent cpd; structure. allergen : A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.. diphenylpyraline : A member of the class of piperidines that is the benzhydryl ether derivative of 1-methyl-4-hydroxypiperidine. A sedating antihistamine, it is used as the hydrochloride for the symptomatic relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders. It is also used as the teoclate salt (piprinhydrinate) as an ingredient in compound preparations for the symptomatic relief of coughs and the common cold.	2.1	1	piperidines; tertiary amine	cholinergic antagonist; H1-receptor antagonist
propane Propane: A three carbon alkane with the formula H3CCH2CH3.	2.1	1	alkane; gas molecular entity	food propellant
isoprene isoprene: used in manufacture of ''synthetic'' rubber, butyl rubber; copolymer in production of elastomers; structure. isoprene : A hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds.	2.15	1	alkadiene; hemiterpene; volatile organic compound	plant metabolite
4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane: RN given refers to parent cpd; structure. 4,4'-diaminodiphenylmethane : An aromatic amine that is diphenylmethane substituted at the 4-position of each benzene ring by an amino group.	1.97	1	aromatic amine	allergen; carcinogenic agent
4-phenylenediamine 4-phenylenediamine: agent hair dye responsible for contact dermatitis; RN given refers to parent cpd. 1,4-phenylenediamine : A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus.	2.42	2	phenylenediamine	allergen; dye; hapten; reagent
disperse orange 3 4-(4-nitrophenylazo)aniline : Azobenzene substituted at the phenyl 4-positions by an amino and a nitro group.	4.38	6	azobenzenes; primary arylamine	allergen; dye
disperse blue 1 [no description available]	2.07	1	anthraquinone
dispersion yellow 3 Dispersion Yellow 3: used in carpet industry; river pollutant. 4-(2-hydroxy-5-methylphenylazo)acetanilide : An azo dye with a structure consisting of acetanilide substituted on the 4-position of the phenyl group with a 6-hydroxy-m-tolylazo group.	2.73	3
disperse red 1 Disperse Red 1 : An azo dye with a structure consisting of nitrobenzene substituted on the 4-position of the phenyl group with a 4-[N-ethyl-N-(2-hydroxyethyl)]phenylazo group.	2.69	3
reactive orange [no description available]	2.05	1
disperse blue 35 disperse blue 35: not a single chemical cpd	2.07	1
melamine formaldehyde [no description available]	2.21	1
disperse blue 106 disperse blue 106: monoazo textile dye used on polyester blouses; no other info available 12/85	5.44	19
basic red 46 basic red 46: monoazoic dye used for acrylic textiles implicated in contact dermatitis	2.06	1
piperidines Piperidines: A family of hexahydropyridines.	2.1	1
reactive blue 21 reactive blue 21: structure in first source	2.05	1
remazol black b Remazol black B: RN given refers to the tetrasodium salt. remazole black-GR : A bis(azo) compound with two aryldiazenyl moieties placed at positions 2 and 7 of a multi-substituted naphthalene.	2.05	1

Condition	Relationship Strength	Studies
Allergic Contact Dermatitis [description not available]	5.48	24
Vitiligo A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.	2.41	1
Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.	5.48	24
Bullous Dermatoses [description not available]	2.25	1
Leg Dermatoses A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed)	2.47	2
Itching [description not available]	2.45	2
Vulvar Diseases Pathological processes of the VULVA.	2.21	1
Pruritus An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.	2.45	2
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.44	2
Dermatitis, Irritant A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms.	2.1	1
Dermatitis, Occupational A recurrent contact dermatitis caused by substances found in the work place.	2.94	4
Complication, Postoperative [description not available]	2.07	1
Injuries Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used.	2.07	1
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	2.07	1
Wounds and Injuries Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.	2.07	1
Facial Dermatoses Skin diseases involving the FACE.	2.01	1
Hand Dermatosis [description not available]	2.01	1
Hand Dermatoses Skin diseases involving the HANDS.	2.01	1
Dermatitis, Eczematous [description not available]	2	1
Eczema A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed).	2	1
Bleb [description not available]	2	1
Erythema Multiforme A skin and mucous membrane disease characterized by an eruption of macules, papules, nodules, vesicles, and/or bullae with characteristic bull's-eye lesions usually occurring on the dorsal aspect of the hands and forearms.	7	1
IgA Vasculitis A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections.	2	1
Contact Dermatitis [description not available]	1.97	1
Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	1.97	1

disperse blue 124

Description

Cross-References

Synonyms (18)

Roles (3)

Drug Classes (3)

Research

Studies (25)

Market Indicators

Research Demand Index: 29.07

Study Types