Page last updated: 2024-11-13

gr 71251

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

GR 71251: tachykinin receptor antagonist [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID25079058
MeSH IDM0205188

Synonyms (10)

Synonym
gr 71251
substance p, prolyl(9)-(spiro-gamma-lactam)-leucyl(10)-tryptophan(11)-
substance p, 9-deglycine-10-((5s)-l-alpha-(2-methylpropyl)-6-oxo-1,7-diazaspiro(4.4)nonane-7-acetic acid)-11-l-tryptophanamide-
substance p, 9-deglycine-10-((5s)-6-oxo-l-alpha-(2-methylpropyl)-1,7-diazaspiro(4.4)nonane-7-acetic acid)-11-l-tryptophanamide-
9-pro-(spiro-gamma-lactam)-10-leu-11-trp substance p
substance p, pro(9)-(spiro-gamma-lactam)-leu(10)-trp(11)-
127493-01-0
gr-71,251
DTXSID40155588
gr71251

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" All the selective NK1 receptor antagonists, tested at the concentration of 10(-5)M, induced a significant displacement to the right of the dose-response curves induced by SP and by the selective NK1 receptor agonist."( Effect of selective tachykinin receptor antagonists on the growth of human skin fibroblasts.
Maggi, CA; Morbidelli, L; Ziche, M, 1993
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's11 (84.62)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.54

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.54 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.18 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.54)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]