Proteins > Trifunctional purine biosynthetic protein adenosine-3
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Trifunctional purine biosynthetic protein adenosine-3
A trifunctional purine biosynthetic protein adenosine-3 that is encoded in the genome of mouse. [OMA:Q64737, PRO:DNx]
Synonyms
Research
Bioassay Publications (5)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (40.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reducJournal of medicinal chemistry, , Feb-11, Volume: 53, Issue:3, 2010
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transpoJournal of medicinal chemistry, , May-14, Volume: 52, Issue:9, 2009
Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.Journal of medicinal chemistry, , Aug-28, Volume: 51, Issue:16, 2008
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reducJournal of medicinal chemistry, , Feb-11, Volume: 53, Issue:3, 2010
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transpoJournal of medicinal chemistry, , May-14, Volume: 52, Issue:9, 2009
Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.Journal of medicinal chemistry, , Aug-28, Volume: 51, Issue:16, 2008