Compounds > phthalocyanine
Page last updated: 2024-09-21

phthalocyanine

Description

phthalocyanine : A tetrapyrrole fundamental parent that consists of four isoindole-type units, with the connecting carbon atoms in the macrocycle replaced by nitrogen. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID86280045
CHEMBL ID262101
CHEBI ID34921
SCHEMBL ID15816
MeSH IDM0061585

Synonyms (47)

Synonym
phthalocyanin
phthalozyanin
CHEBI:34921 ,
ftalocianina
29h,31h-phthalocyanine
574-93-6
phthalocyanine
29h,31h-phthalocyanine, beta-form, 98%
ci 74100
hsdb 4350
lionol blue kw
29h, 31h-phthalocyanine
einecs 209-378-3
5,28:14,19-diimino-7,12:26,21-dinitrilotetrabenzo(c,h,m,r)(1,6,11,16)tetraazacycloeicosine
tetrabenzo(b,g,l,q)porphyrazine
heliogen blue 7560
monolite fast blue gs
heliogen blue 7800
irgazin blue 3gt
heliogen blue g
P1795
CHEMBL262101
ciaftalan
P0355
unii-v5puf4vlgy
v5puf4vlgy ,
ec 209-378-3
AKOS015912687
5,28:14,19-diimino-7,12:26,21- dinitrilotetrabenzo(c,h,m,r)(1,6,11,16)tetraazacycloeicosine
.chi.-phthalocyanine
ci 74100 [inci]
tetrabenzotetraazaporphine
phthalocyanine [hsdb]
SCHEMBL15816
521983-41-5
5,28-dihydro-29h,31h-phthalocyanine
mfcd00005085
DTXSID9025906
AS-39343
phthalocyanine (purified by sublimation)
phthalocyanine, (purified by sublimation)
YSWG725
?29h,31h-phthalocyanine
CS-0081409
phthalocyanine (purified by sublimation) [for organic electronics]
P2734
SY009954

Drug Classes (2)

ClassDescription
tetrapyrrole fundamental parent
phthalocyaninesCompounds containing a phthalocyanine skeleton.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID322957Inhibition of synthetic amyloid beta-42 fibrillation by ThT fluorescence analysis relative to control2007The Journal of biological chemistry, Apr-06, Volume: 282, Issue:14
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
AID322958Inhibition of synthetic amyloid beta-42 fibrillation by light scattering analysis relative to control2007The Journal of biological chemistry, Apr-06, Volume: 282, Issue:14
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (1,206)

TimeframeStudies, This Drug (%)All Drugs %
pre-199050 (4.15)18.7374
1990's95 (7.88)18.2507
2000's281 (23.30)29.6817
2010's579 (48.01)24.3611
2020's201 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials9 (0.73%)5.53%
Reviews91 (7.36%)6.00%
Case Studies1 (0.08%)4.05%
Observational0 (0.00%)0.25%
Other1,136 (91.84%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
melatonin[no description available]medium10acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
thiophane[no description available]medium10saturated organic heteromonocyclic parent;
tetrahydrothiophenes
fenofibrate[no description available]medium10aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
indomethacin[no description available]medium10aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
juglone[no description available]medium10hydroxy-1,4-naphthoquinonegeroprotector;
herbicide;
reactive oxygen species generator
masoprocol[no description available]medium10catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite
perphenazine[no description available]medium10N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
phenolsulfonphthalein[no description available]medium102,1-benzoxathiole;
arenesulfonate ester;
phenols;
sultone		acid-base indicator;
diagnostic agent;
two-colour indicator
cetrimonium bromide[no description available]medium10organic bromide salt;
quaternary ammonium salt		detergent;
surfactant
p-dimethylaminoazobenzene[no description available]medium10azobenzenes
2-vanillin[no description available]medium10benzaldehydes;
guaiacols		antimutagen;
plant metabolite
1,2-naphthoquinone[no description available]medium101,2-naphthoquinonesaryl hydrocarbon receptor agonist;
carcinogenic agent
eosine yellowish-(ys)[no description available]medium10organic sodium salt;
organobromine compound		fluorochrome;
histological dye
congo red[no description available]medium10bis(azo) compound
orange g[no description available]medium10
pontamine sky blue[no description available]medium10
daunorubicin hydrochloride[no description available]medium10anthracycline
neocuproine[no description available]medium10phenanthrolineschelator;
copper chelator
2,2'-Dihydroxybenzophenone[no description available]medium10benzophenones
c.i. basic blue 41[no description available]medium10
betadex[no description available]medium80cyclodextrin
apigenin[no description available]medium10trihydroxyflavoneantineoplastic agent;
metabolite
myricetin[no description available]medium107-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite
rifamycin sv[no description available]medium10acetate ester;
cyclic ketal;
lactam;
macrocycle;
organic heterotetracyclic compound;
polyphenol;
rifamycins		antimicrobial agent;
antitubercular agent;
bacterial metabolite
nystatin a1[no description available]medium10nystatins
meclan[no description available]medium10
rolitetracycline[no description available]medium10
azure c[no description available]medium10
folic acid[no description available]medium40folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
sulfur[no description available]medium80chalcogen;
nonmetal atom		macronutrient
singlet oxygen[no description available]medium910chalcogen;
monoatomic oxygen;
nonmetal atom		macronutrient
gold[no description available]medium370copper group element atom;
elemental gold
indium[no description available]medium110boron group element atom
1,1-diphenyl-2-picrylhydrazyl[no description available]medium50
aluminum[no description available]medium161boron group element atom;
elemental aluminium;
metal atom
lysine[no description available]medium30aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
zn(ii)-phthalocyanine[no description available]medium380metallophthalocyanine;
zinc tetrapyrrole		fluorochrome
arginyl-glycyl-aspartic acid[no description available]medium40oligopeptide
alcian blue[no description available]medium40
cobalt[no description available]medium300cobalt group element atom;
metal allergen		micronutrient
chitosan[no description available]medium100
beta-escin[no description available]medium10
lithium[no description available]medium50alkali metal atom
fluorine[no description available]medium60diatomic fluorine;
gas molecular entity		NMR chemical shift reference compound
deuterium[no description available]medium10dihydrogen
alanine[no description available]medium10alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
leucine[no description available]medium10amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
valine[no description available]medium20L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
caprolactone[no description available]medium10epsilon-lactone
zinc oxide[no description available]medium40zinc molecular entity
nickel[no description available]medium310metal allergen;
nickel group element atom		epitope;
micronutrient
ascorbic acid[no description available]medium90ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
methane[no description available]medium210alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
diclofenac[no description available]medium20amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
lutetium[no description available]medium80d-block element atom;
lanthanoid atom
zinc(ii) phthalocyanine trisulfonic acid[no description available]medium90
rhenium[no description available]medium20manganese group element atom
phosphatidylcholines[no description available]medium201,2-diacyl-sn-glycero-3-phosphocholine
chloroform[no description available]medium80chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
phenylthiourea[no description available]medium10thioureasEC 1.14.18.1 (tyrosinase) inhibitor
perrhenate[no description available]medium10monovalent inorganic anion;
rhenium oxoanion
deanol[no description available]medium10ethanolamines;
tertiary amine		curing agent;
radical scavenger
acetonitrile[no description available]medium20aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
cobalt phthalocyanine[no description available]medium50
dysprosium[no description available]medium40f-block element atom;
lanthanoid atom
gadolinium[no description available]medium20f-block element atom;
lanthanoid atom
kanamycin a[no description available]medium10kanamycinsbacterial metabolite
ethidium[no description available]medium20phenanthridinesfluorochrome;
intercalator
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
vitamin b 12[no description available]medium10
silicon phthalocyanine pc4[no description available]medium30
n-succinimidyl-5-iodo-3-pyridinecarboxylic acid[no description available]medium10
gallic acid[no description available]medium10trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
silicon[no description available]medium320carbon group element atom;
metalloid atom;
nonmetal atom
hydrogen[no description available]medium100elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
dimethyl sulfoxide[no description available]medium70sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
hypochlorous acid[no description available]medium10chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
silver[no description available]medium100copper group element atom;
elemental silver		Escherichia coli metabolite
tin[no description available]medium50carbon group element atom;
elemental tin;
metal atom		micronutrient
pyrroles[no description available]medium80pyrrole;
secondary amine
n-vinyl-2-pyrrolidinone[no description available]medium10pyrrolidin-2-ones
nicotine[no description available]medium203-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
promazine[no description available]medium10phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
aluminum phthalocyanine[no description available]medium110organic molecular entity
sepharose[no description available]medium10
fluorides[no description available]medium70halide anion;
monoatomic fluorine
vanillin[no description available]medium10benzaldehydes;
monomethoxybenzene;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
flavouring agent;
plant metabolite
isoniazid[no description available]medium20carbohydrazideantitubercular agent;
drug allergen
chlorin[no description available]medium140
gallium[no description available]medium90boron group element atom
perylene[no description available]medium170ortho- and peri-fused polycyclic arene;
perylenes
aminolevulinic acid[no description available]medium904-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid		antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
hypericin[no description available]medium30
biotin[no description available]medium40biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
transferrin[no description available]medium30
boranes[no description available]medium10boranes;
mononuclear parent hydride
perylenediimide[no description available]medium60dicarboximide;
organic heteropolycyclic compound		fluorochrome
azides[no description available]medium70pseudohalide anionmitochondrial respiratory-chain inhibitor
triethylene glycol[no description available]medium10diol;
poly(ethylene glycol);
primary alcohol		plasticiser
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
methionine[no description available]medium20aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
nitrites[no description available]medium40monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
fluorexon[no description available]medium10xanthene dyefluorochrome
erythrosine[no description available]medium40
laccase[no description available]medium40
catechol[no description available]medium10catecholsallelochemical;
genotoxin;
plant metabolite
lactose[no description available]medium20lactose
ammonium hydroxide[no description available]medium20azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
boron[no description available]medium60boron group element atom;
metalloid atom;
nonmetal atom		micronutrient
cellulose[no description available]medium50glycoside
ciprofloxacin[no description available]medium10aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
trifluoroacetic acid[no description available]medium20fluoroalkanoic acidhuman xenobiotic metabolite;
NMR chemical shift reference compound;
reagent
benzene[no description available]medium40aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
e 3330[no description available]medium10
perfluoropentane[no description available]medium10fluoroalkane;
fluorocarbon		radioopaque medium;
ultrasound contrast agent
as 1411[no description available]medium10
naphthosultone[no description available]medium10
ampicillin[no description available]medium10beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
amyloid beta-peptides[no description available]medium30
physostigmine[no description available]medium10carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene[no description available]medium80BODIPY compound
triazoles[no description available]medium701,2,3-triazole
zirconium[no description available]medium70titanium group element atom
dehydroacetic acid[no description available]medium10ketone;
pyran-2,4-dione		antibacterial agent;
fungicide;
plasticiser
titanium[no description available]medium220titanium group element atom
titanium dioxide[no description available]medium120titanium oxidesfood colouring
hafnium[no description available]medium30titanium group element atom
cyclohexane[no description available]medium10cycloalkane;
volatile organic compound		non-polar solvent
corrole[no description available]medium40
palladium[no description available]medium80metal allergen;
nickel group element atom;
platinum group metal atom
muramidase[no description available]medium20
2,3,4,6-tetrachlorophenol[no description available]medium20tetrachlorophenolxenobiotic metabolite
2-chlorophenol[no description available]medium102-halophenol;
monochlorophenol
1-naphthol[no description available]medium20naphtholgenotoxin;
human xenobiotic metabolite
2-furoic acid[no description available]medium10furoic acidbacterial xenobiotic metabolite;
human xenobiotic metabolite;
inhibitor;
plant metabolite;
Saccharomyces cerevisiae metabolite
2-naphthol[no description available]medium30naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
temoporfin[no description available]medium20
aluminum tetrasulfophthalocyanine[no description available]medium60
aluminum phthalocyanine disulfonate[no description available]medium20
ruthenium[no description available]medium50iron group element atom;
platinum group metal atom
pyridine[no description available]medium50azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
methylparaben[no description available]medium10parabenantifungal agent;
antimicrobial food preservative;
neuroprotective agent;
plant metabolite
propylparaben[no description available]medium10benzoate ester;
paraben;
phenols		antifungal agent;
antimicrobial agent
tirapazamine[no description available]medium10aromatic amine;
benzotriazines;
N-oxide		antibacterial agent;
antineoplastic agent;
apoptosis inducer
porphycene[no description available]medium10
lead[no description available]medium20carbon group element atom;
elemental lead;
metal atom		neurotoxin
bacteriochlorophyll b[no description available]medium10
bacteriochlorophylls[no description available]medium10
fluorescein[no description available]medium202-benzofurans;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
polyphenol;
xanthene dye		fluorescent dye;
radioopaque medium
methylene blue[no description available]medium80organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
proflavine[no description available]medium10aminoacridinesantibacterial agent;
antiseptic drug;
carcinogenic agent;
chromophore;
intercalator
protoporphyrin ix[no description available]medium20
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
iridium[no description available]medium10cobalt group element atom;
platinum group metal atom
warfarin[no description available]medium20benzenes;
hydroxycoumarin;
methyl ketone
coumarin[no description available]medium20coumarinsfluorescent dye;
human metabolite;
plant metabolite
carbazole[no description available]medium10carbazole
helium[no description available]medium30monoatomic helium;
noble gas atom;
s-block element atom		food packaging gas
dimethylformamide[no description available]medium30formamides;
volatile organic compound		geroprotector;
hepatotoxic agent;
polar aprotic solvent
phenylalanine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenylalanylphenylalanine[no description available]medium10
mitoxantrone[no description available]medium10dihydroxyanthraquinoneanalgesic;
antineoplastic agent
pyrene[no description available]medium30ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
phosphorus[no description available]medium40monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
tempo[no description available]medium40aminoxyls;
piperidines		catalyst;
ferroptosis inhibitor;
radical scavenger
erythromycin[no description available]medium10cyclic ketone;
erythromycin
mercury[no description available]medium10elemental mercury;
zinc group element atom		neurotoxin
methotrexate[no description available]medium10dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
glycidyl methacrylate[no description available]medium20enoate ester;
epoxide
ethylene dimethacrylate[no description available]medium20enoate esterallergen;
cross-linking reagent;
polymerisation monomer
acrylic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acidmetabolite
allopurinol[no description available]medium10nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
chalcone[no description available]medium30chalconeEC 3.2.1.1 (alpha-amylase) inhibitor
gma-edma[no description available]medium10
bisphenol a[no description available]medium20bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
coumestrol[no description available]medium10coumestans;
delta-lactone;
polyphenol		anti-inflammatory agent;
antioxidant;
plant metabolite
manganese[no description available]medium150elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
estrone[no description available]medium1017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
phytoestrogens[no description available]medium10
reactive blue 21[no description available]medium30
thymine[no description available]medium20pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
curdlan[no description available]medium10hexose
epiglucan[no description available]medium10
dabrafenib[no description available]medium101,3-thiazoles;
aminopyrimidine;
organofluorine compound;
sulfonamide		anticoronaviral agent;
antineoplastic agent;
B-Raf inhibitor
trametinib[no description available]medium10acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
pyrimidinones[no description available]medium30
peroxymonosulfate[no description available]medium10sulfur oxide;
sulfur oxoanion
iminodiacetic acid[no description available]medium10amino dicarboxylic acid;
glycine derivative;
non-proteinogenic alpha-amino acid		chelator
benzothiazole[no description available]medium20benzothiazolesenvironmental contaminant;
plant metabolite;
xenobiotic
indium trichloride[no description available]medium10
colistin[no description available]medium10
oligonucleotides[no description available]medium130
tetraphenylporphine[no description available]medium10
boron nitride[no description available]medium10nitride
hydroxyl radical[no description available]medium50oxygen hydride;
oxygen radical;
reactive oxygen species
methyl orange[no description available]medium20
tert-butylhydroperoxide[no description available]medium20alkyl hydroperoxideantibacterial agent;
oxidising agent
heme[no description available]medium50
platinum[no description available]medium60elemental platinum;
nickel group element atom;
platinum group metal atom
rhodamine b[no description available]medium30organic chloride salt;
xanthene dye		fluorescent probe;
fluorochrome;
histological dye
2,2'-dipyridyl[no description available]medium10bipyridinechelator;
ferroptosis inhibitor
vpm chloride[no description available]medium10
chlorophyll a[no description available]medium60chlorophyll;
methyl ester		cofactor
alkenes[no description available]medium30
rhodamine 6g[no description available]medium10
pyronine[no description available]medium10iminium salt;
organic chloride salt		histological dye
xanthenes[no description available]medium20xanthene
fullerene c60[no description available]medium350fullerenegeroprotector
zeolites[no description available]medium10
metronidazole[no description available]medium10C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid[no description available]medium10azamacrocyclechelator;
copper chelator
1,4,7-triazacyclononane-n,n',n''-triacetic acid[no description available]medium10
chlorine[no description available]medium40halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
fullerene c70[no description available]medium10fullerene
terbium[no description available]medium60f-block element atom;
lanthanoid atom
yttrium[no description available]medium20d-block element atom;
rare earth metal atom;
scandium group element atom
sarin[no description available]medium10fluorine molecular entity;
phosphinic ester
molybdenum[no description available]medium30chromium group element atommicronutrient
quinoxaline-2-carboxylic acid[no description available]medium10
quinoxalines[no description available]medium20mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
pyrazines[no description available]medium20diazine;
pyrazines		Daphnia magna metabolite
mesoporphyrin ix[no description available]medium10
hydrogen sulfide[no description available]medium10gas molecular entity;
hydracid;
mononuclear parent hydride;
sulfur hydride		Escherichia coli metabolite;
genotoxin;
metabolite;
signalling molecule;
toxin;
vasodilator agent
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
2-dichlorobenzene[no description available]medium20dichlorobenzenehepatotoxic agent;
metabolite
toluene[no description available]medium70methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
malachite green[no description available]medium20organic chloride saltantibacterial agent;
antifungal drug;
carcinogenic agent;
environmental contaminant;
fluorochrome;
histological dye;
teratogenic agent
c.i. 42510[no description available]medium31
triphenylmethane[no description available]medium10triarylmethaneenvironmental contaminant;
xenobiotic
benzophenoneidum[no description available]medium10hydrochloridefluorochrome;
histological dye
pyocyanine[no description available]medium10iminium betaine;
phenazines		antibacterial agent;
bacterial metabolite;
biological pigment;
virulence factor
imidazole[no description available]medium10imidazole
isophthalate[no description available]medium10dicarboxylic acid dianion
tetrahydrofuran[no description available]medium40cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound		polar aprotic solvent
aluminum oxide[no description available]medium40
fenton's reagent[no description available]medium20
gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate[no description available]medium10
methanol[no description available]medium50alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
bacteriochlorin[no description available]medium20
va 061[no description available]medium10
chlorpromazine[no description available]medium20organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
dimethyldioctadecylammonium[no description available]medium10
formic acid[no description available]medium10monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent
remazol black b[no description available]medium10
carbene[no description available]medium10carbene;
methanediyl
styrene[no description available]medium10styrenes;
vinylarene;
volatile organic compound		mouse metabolite;
mutagen;
plant metabolite
naphthalenediimide[no description available]medium10
zinc naphthalocyanine[no description available]medium20
bacteriochlorin a[no description available]medium10
phosphonic acid[no description available]medium10
1,4-dioxane[no description available]medium10dioxane;
volatile organic compound		carcinogenic agent;
metabolite;
NMR chemical shift reference compound;
non-polar solvent
cyanoginosin lr[no description available]medium20microcystinbacterial metabolite;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
environmental contaminant;
xenobiotic
choline[no description available]medium20cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
4,4'-bipyridyl[no description available]medium10bipyridine
ethylene[no description available]medium10alkene;
gas molecular entity		plant hormone;
refrigerant
perylenetetracarboxylic diimide[no description available]medium10
chondroitin sulfates[no description available]medium10
triethanolamine[no description available]medium10amino alcohol;
tertiary amino compound;
triol		buffer;
surfactant
adamantane[no description available]medium10adamantanes;
polycyclic alkane
carboxymethyl-beta-cyclodextrin[no description available]medium10
copper phthalocyanine[no description available]medium50
sodium dodecyl sulfate[no description available]medium10organic sodium saltdetergent;
protein denaturant
carbamazepine[no description available]medium10dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
sodium hydroxide[no description available]medium20alkali metal hydroxide
calixarenes[no description available]medium20
europium[no description available]medium50f-block element atom;
lanthanoid atom
porphine[no description available]medium40
glycine[no description available]medium20alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
melamine[no description available]medium10triamino-1,3,5-triazinexenobiotic metabolite
cyanides[no description available]medium20pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
acetaminophen[no description available]medium10acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
phenyl acetate[no description available]medium10benzenes;
phenyl acetates
rubrene[no description available]medium10
o(6)-benzylguanine[no description available]medium10
guanine[no description available]medium202-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
acetic acid[no description available]medium10monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
arginine[no description available]medium10arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
glutamic acid[no description available]medium10glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
iodine[no description available]medium10halide anion;
monoatomic iodine		human metabolite
Brilliant Blue[no description available]medium11organic molecular entity
sulfan blue[no description available]medium11organic molecular entity
camptothecin[no description available]medium10delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
1,4-dihydropyridine[no description available]medium10
dihydropyridines[no description available]medium10
cobaltiprotoporphyrin[no description available]medium10
15-crown-5[no description available]medium10crown ether;
saturated organic heteromonocyclic parent
galactose[no description available]medium40D-galactose;
galactopyranose		Escherichia coli metabolite;
mouse metabolite
luminol[no description available]medium10
rutin[no description available]medium10disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone		antioxidant;
metabolite
rhodium[no description available]medium20cobalt group element atom
cytochrome c-t[no description available]medium20
cadmium[no description available]medium50cadmium molecular entity;
zinc group element atom
pentacene[no description available]medium10acene;
pentacenes
glycosides[no description available]medium20
1,2-benzenedicarbonitrile[no description available]medium10
zinc hematoporphyrin[no description available]medium40
mercaptoethanol[no description available]medium30alkanethiol;
primary alcohol		geroprotector
2'-deoxyguanosine 5'-phosphate[no description available]medium10deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
mouse metabolite
cupric glycinate[no description available]medium10
2,4-dichlorophenoxyacetic acid[no description available]medium10chlorophenoxyacetic acid;
dichlorobenzene		agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin
magnesium perchlorate[no description available]medium10alkaline earth salt
4-xylene[no description available]medium10xylene
menthol[no description available]medium20p-menthane monoterpenoid;
secondary alcohol		volatile oil component
acetone[no description available]medium20ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
zinc nitrate[no description available]medium10
nitrates[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
sodium borohydride[no description available]medium10inorganic sodium salt;
metal tetrahydridoborate
guanidine[no description available]medium20carboxamidine;
guanidines;
one-carbon compound
chlorine[no description available]medium50diatomic chlorine;
gas molecular entity		bleaching agent
bromine[no description available]medium10diatomic bromine
hydroquinone[no description available]medium10benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent
cerium[no description available]medium20f-block element atom;
lanthanoid atom
carbocyanines[no description available]medium40cyanine dye;
organic iodide salt		fluorochrome
2,4-dichlorophenol[no description available]medium10dichlorophenol
dipyrromethene[no description available]medium10dipyrrins
porphobilinogen[no description available]medium10aralkylamino compound;
dicarboxylic acid;
pyrroles		Escherichia coli metabolite;
metabolite;
mouse metabolite
orabase[no description available]medium10
edetic acid[no description available]medium10ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
cytochalasin d[no description available]medium10
1,2-dipalmitoylphosphatidylcholine[no description available]medium10
lignin[no description available]medium20
pentalysine[no description available]medium10
azulene[no description available]medium10azulenes;
mancude carbobicyclic parent;
ortho-fused bicyclic arene		plant metabolite;
volatile oil component
dithioerythritol[no description available]medium101,4-dimercaptobutane-2,3-diolreducing agent
fluorosulfonic acid[no description available]medium20sulfur oxoacidNMR solvent
wortmannin[no description available]medium10acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
talaporfin[no description available]medium10
sulfur dioxide[no description available]medium10sulfur oxideEscherichia coli metabolite;
food bleaching agent;
refrigerant
9,9-bis(4-hydroxyphenyl)fluorene[no description available]medium10fluorenes;
polyphenol		anti-estrogen
1-monooleoyl-rac-glycerol[no description available]medium101-acylglycerol 18:1;
monooleoylglycerol		plant metabolite
oleic acid[no description available]medium10octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
epidermal growth factor[no description available]medium20
malaoxon[no description available]medium10diester;
ethyl ester;
organic thiophosphate
malathion[no description available]medium10diester;
ethyl ester;
organic thiophosphate
paraoxon[no description available]medium10aryl dialkyl phosphate;
organophosphate insecticide		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite
diphenyl[no description available]medium10aromatic fungicide;
benzenes;
biphenyls		antifungal agrochemical;
antimicrobial food preservative
ovalbumin[no description available]medium20
nad[no description available]medium20organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
vanadium[no description available]medium30elemental vanadium;
vanadium group element atom		micronutrient
phenanthrene[no description available]medium10ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon;
phenanthrenes		environmental contaminant;
mouse metabolite
thiophenes[no description available]medium20mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
phenanthrenes[no description available]medium10
18-crown-6[no description available]medium10crown ether;
saturated organic heteromonocyclic parent		phase-transfer catalyst
alpha-synuclein[no description available]medium20
piperidines[no description available]medium10
ferrous sulfate[no description available]medium10iron molecular entity;
metal sulfate		reducing agent
arachidic acid[no description available]medium10long-chain fatty acid;
straight-chain saturated fatty acid		plant metabolite
cyclopentane[no description available]medium20cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
propyleneimine[no description available]medium10aziridines
bafilomycin a[no description available]medium10
tungsten[no description available]medium10chromium group element atommicronutrient
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone[no description available]medium10
tellurium[no description available]medium10chalcogen;
metalloid atom
cadmium telluride[no description available]medium10
benzofuran[no description available]medium101-benzofurans;
benzofuran
benzofurans[no description available]medium20
antimony[no description available]medium30metalloid atom;
pnictogen
germanium[no description available]medium20carbon group element atom;
metalloid atom;
nonmetal atom
tetrabutylammonium[no description available]medium10quaternary ammonium ion
tretinoin[no description available]medium10retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
arsenic[no description available]medium10metalloid atom;
pnictogen		micronutrient
ethylene dichloride[no description available]medium10chloroethaneshepatotoxic agent;
mutagen;
non-polar solvent
fenamiphos[no description available]medium10organophosphate insecticide;
organophosphate nematicide;
phosphoramidate ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
pentachlorophenol[no description available]medium20aromatic fungicide;
chlorophenol;
organochlorine pesticide;
pentachlorobenzenes		human xenobiotic metabolite
2,6-diaminoanthraquinone[no description available]medium10
2,6-dihydroxyanthraquinone[no description available]medium10dihydroxyanthraquinoneantimutagen;
plant metabolite
lanthanum[no description available]medium10f-block element atom;
lanthanoid atom;
scandium group element atom
thiazolyl blue[no description available]medium10organic bromide saltcolorimetric reagent;
dye
thiazoles[no description available]medium101,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
carbon monoxide[no description available]medium10carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
soda lime[no description available]medium10
ethylenediamine[no description available]medium10alkane-alpha,omega-diamineGABA agonist
triphenylene[no description available]medium10ortho-fused polycyclic arene
pheophorbide a[no description available]medium10
cyanine dye 1[no description available]medium10
thioridazine[no description available]medium10phenothiazines;
piperidines		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
gastrin-releasing peptide[no description available]medium10
oxalic acid[no description available]medium10alpha,omega-dicarboxylic acidalgal metabolite;
human metabolite;
plant metabolite
cysteine[no description available]medium30cysteiniumfundamental metabolite
ferrous oxide[no description available]medium10iron oxide
osmium tetroxide[no description available]medium10osmium coordination entityfixative;
histological dye;
oxidising agent;
poison
tolonium chloride[no description available]medium20
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
retinol[no description available]medium10retinol;
vitamin A		human metabolite;
mouse metabolite;
plant metabolite
hematoporphyrin[no description available]medium140
heliogen blue sbl[no description available]medium10
9-nitroanthracene[no description available]medium10anthracenes
nitroxyl[no description available]medium10nitrogen oxoacid
hematoxylin[no description available]medium10organic heterotetracyclic compound;
oxacycle;
polyphenol;
tertiary alcohol		histological dye;
plant metabolite
tryptophan[no description available]medium30erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
potassium bromide[no description available]medium10potassium salt
bromide[no description available]medium10halide anion;
monoatomic bromine
pyropheophorbide a[no description available]medium10
procion blue mx-r[no description available]medium10
phenothiazine[no description available]medium10phenothiazineferroptosis inhibitor;
plant metabolite;
radical scavenger
tert-butyl alcohol[no description available]medium10tertiary alcoholhuman xenobiotic metabolite
n-butylamine[no description available]medium10primary aliphatic amine
tetrachloroethylene[no description available]medium10chlorocarbon;
chloroethenes		nephrotoxic agent
fluorodeoxyglucose f18[no description available]medium102-deoxy-2-((18)F)fluoro-D-glucose;
2-deoxy-2-fluoro-aldehydo-D-glucose
tetramethylsilane[no description available]medium10organosilicon compoundNMR chemical shift reference compound
perchlorate[no description available]medium10chlorine oxoanion;
monovalent inorganic anion
citric acid, anhydrous[no description available]medium10tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
cytidine[no description available]medium10cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanosine[no description available]medium10guanosines;
purines D-ribonucleoside		fundamental metabolite
paraquat[no description available]medium10organic cationgeroprotector;
herbicide
4-nitrophenol[no description available]medium104-nitrophenolshuman xenobiotic metabolite;
mouse metabolite
nitrophenols[no description available]medium10
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
levodopa[no description available]medium10amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
cetyltrimethylammonium ion[no description available]medium10quaternary ammonium ion
allylamine[no description available]medium10alkylamine
diphenylamine[no description available]medium10aromatic amine;
bridged diphenyl fungicide;
secondary amino compound		antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger
hydroxide ion[no description available]medium10oxygen hydridemouse metabolite
uric acid[no description available]medium10uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
veratryl alcohol[no description available]medium10benzyl alcohols;
dimethoxybenzene;
primary alcohol		fungal metabolite
gramicidin a[no description available]medium40
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid[no description available]medium10chromanol;
monocarboxylic acid;
phenols		antioxidant;
ferroptosis inhibitor;
neuroprotective agent;
radical scavenger;
Wnt signalling inhibitor
5,5-dimethyl-1-pyrroline-1-oxide[no description available]medium201-pyrroline nitronesneuroprotective agent;
spin trapping reagent
safranine t[no description available]medium10organic chloride saltfluorochrome;
histological dye
theophylline[no description available]medium10dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
digoxin[no description available]medium10cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
cobalt tetrasulfophthalocyanine[no description available]medium10
dimethyl sulfide[no description available]medium10aliphatic sulfidealgal metabolite;
bacterial xenobiotic metabolite;
EC 3.5.1.4 (amidase) inhibitor;
Escherichia coli metabolite;
marine metabolite
merocyanine dye[no description available]medium20
egtazic acid[no description available]medium10diether;
tertiary amino compound;
tetracarboxylic acid		chelator
deuterium oxide[no description available]medium10deuterated compound;
water		NMR solvent
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
neon[no description available]medium10monoatomic neon;
noble gas atom;
p-block element atom
gamma-cyclodextrin[no description available]medium10cyclodextrin
6-ketocholestanol[no description available]medium10cholestanoid
phloretin[no description available]medium10dihydrochalconesantineoplastic agent;
plant metabolite
thyronines[no description available]medium10thyronine
rh 421[no description available]medium10
1,2-diphytanoylphosphatidylcholine[no description available]medium10
calcein am[no description available]medium102-benzofurans;
acetate ester;
gamma-lactone;
organic heteropentacyclic compound;
oxaspiro compound;
xanthene dye		fluorochrome
atrazine[no description available]medium10chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
n-isopropylacrylamide[no description available]medium10
d-alpha tocopherol[no description available]medium10alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
thymidylyl-(3',5')-2'-deoxyguanosine[no description available]medium10
deoxyguanosine[no description available]medium10purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
fusidic acid[no description available]medium1011alpha-hydroxy steroid;
3alpha-hydroxy steroid;
alpha,beta-unsaturated monocarboxylic acid;
steroid acid;
steroid antibiotic;
sterol ester		EC 2.7.1.33 (pantothenate kinase) inhibitor;
Escherichia coli metabolite;
protein synthesis inhibitor
nitrosobis(2-oxopropyl)amine[no description available]medium10ketone;
nitrosamine		carcinogenic agent
hypocrellin a[no description available]medium10
phenol[no description available]medium10phenolsantiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite
1,3-diphenylisobenzofuran[no description available]medium10
chloroaluminum tetrasulfophthalocyanine[no description available]medium20
1,2-dimethylhydrazine[no description available]medium10hydrazinesalkylating agent;
carcinogenic agent
dimethylhydrazines[no description available]medium10
tetradecanoylphorbol acetate[no description available]medium10acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
calcimycin[no description available]medium10benzoxazole
mannitol[no description available]medium10mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
acridine orange[no description available]medium10aminoacridines;
aromatic amine;
tertiary amino compound		fluorochrome;
histological dye
tyrosine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
benzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
bromodeoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
sodium salicylate[no description available]medium10organic molecular entity
ConditionIndicatedRelationship StrengthStudiesTrials
2019 Novel Coronavirus Disease0medium74
2019 Novel Coronavirus Infection0medium74
2019-nCoV Disease0medium74
2019-nCoV Infection0medium74
Abrasion, Dental0low10
Actinic Reticuloid Syndrome0low30
Acute Confusional Senile Dementia0low20
Acute Hemolytic Transfusion Reaction0low10
Acute Lymphoid Leukemia0low10
Adenocarcinoma0low80
Adenocarcinoma of Lung0low10
Adenocarcinoma, Basal Cell0low80
Adenocarcinoma, Granular Cell0low80
Adenocarcinoma, Oxyphilic0low80
Adenocarcinoma, Tubular0low80
Adenoma, Malignant0low80
Adult Periodontitis0medium11
Age-Related Macular Degeneration0low10
Age-Related Maculopathies0low10
Age-Related Maculopathy0low10
ALL, Childhood0low10
Alloxan Diabetes0low10
Alzheimer Dementia0low20
Alzheimer Disease0low20
Alzheimer Disease, Early Onset0low20
Alzheimer Disease, Late Onset0low20
Alzheimer Sclerosis0low20
Alzheimer Syndrome0low20
Alzheimer Type Senile Dementia0low20
Alzheimer-Type Dementia (ATD)0low20
Alzheimer's Disease0low20
Alzheimer's Disease, Focal Onset0low20
Alzheimer's Diseases0low20
American Trypanosomiasis0low10
Amyloid Deposits0low10
Amyloid Plaques0low10
Angioblastic Meningioma0low10
Angiogenesis, Pathologic0low10
Angiogenesis, Pathological0low10
Angiomatous Meningioma0low10
Angiosarcoma0low10
Animal Mammary Carcinoma0low10
Anoxemia0low20
Anoxia0low20
Arteriosclerosis0low20
Astrocytoma, Grade IV0low10
Atheroma0low10
Atheromatous Plaque0low10
Atheromatous Plaques0low10
Atherosclerotic Plaque0low10
Atherosclerotic Plaques0low10
B16 Melanoma0low50
Bacteremia0low10
Bacterial Disease0low10
Bacterial Infection0low10
Bacterial Infections0low10
Bacterial Infections, Gram-Negative0low10
Benign Meningioma0low10
Benign Neoplasms0medium631
Benign Neoplasms, Brain0low50
Bladder Cancer0low50
Bladder Neoplasms0low50
Bladder Tumors0low50
Blood Clot0low10
Blood Transfusion-Associated Adverse Reactions0low10
Brain Cancer0low50
Brain Metastases0low50
Brain Neoplasm, Primary0low50
Brain Neoplasms0low50
Brain Neoplasms, Benign0low50
Brain Neoplasms, Malignant0low50
Brain Neoplasms, Malignant, Primary0low50
Brain Neoplasms, Primary Malignant0low50
Brain Tumor, Primary0low50
Brain Tumor, Recurrent0low50
Brain Tumors0low50
Breast Cancer0low160
Breast Carcinoma0low160
Breast Neoplasms0low160
Breast Tumors0low160
Bronchitis0low10
Burns0low10
Calcification, Pathologic0low20
Calcinosis0low20
Calcinosis, Tumoral0low20
Cancer0medium631
Cancer of Bladder0low50
Cancer of Brain0low50
Cancer of Breast0low160
Cancer of Cervix0low40
Cancer of Colon0low110
Cancer of Digestive System0low10
Cancer of Esophagus0low30
Cancer of Head0low20
Cancer of Head and Neck0low20
Cancer of Larynx0low10
Cancer of Liver0low60
Cancer of Lung0low70
Cancer of Nasopharynx0low30
Cancer of Neck0low20
Cancer of Ovary0low60
Cancer of Pancreas0low30
Cancer of Prostate0low50
Cancer of Skin0low70
Cancer of Stomach0low10
Cancer of the Bladder0low50
Cancer of the Brain0low50
Cancer of the Breast0low160
Cancer of the Cervix0low40
Cancer of the Colon0low110
Cancer of the Digestive System0low10
Cancer of the Esophagus0low30
Cancer of the Head0low20
Cancer of the Head and Neck0low20
Cancer of the Larynx0low10
Cancer of the Liver0low60
Cancer of the Lung0low70
Cancer of the Nasopharynx0low30
Cancer of the Neck0low20
Cancer of the Ovary0low60
Cancer of the Pancreas0low30
Cancer of the Prostate0low50
Cancer of the Skin0low70
Cancer of the Stomach0low10
Cancer of the Uterine Cervix0low40
Cancer, Hepatocellular0low60
Carcinoma0low40
Carcinoma, Anaplastic0low40
Carcinoma, Cribriform0low80
Carcinoma, Epidermoid0low20
Carcinoma, Granular Cell0low80
Carcinoma, Hepatocellular0low40
Carcinoma, Lewis Lung0low20
Carcinoma, Planocellular0low20
Carcinoma, Spindle-Cell0low40
Carcinoma, Squamous0low20
Carcinoma, Squamous Cell0low20
Carcinoma, Tubular0low80
Carcinoma, Undifferentiated0low40
Carcinomatosis0low40
Cerebral Convexity Meningioma0low10
Cervical Cancer0low40
Cervical Neoplasms0low40
Cervix Cancer0low40
Cervix Neoplasms0low40
Chagas Disease0low10
Chagas' Disease0low10
Chest Pain0medium22
Cholangiocarcinoma0low10
Cholangiocellular Carcinoma0low10
Chronic Actinic Dermatitis0low30
Chronic Periodontitis0medium11
Clear Cell Meningioma0low10
Colon Cancer0low110
Colon Neoplasms0low110
Colonic Cancer0low110
Colonic Neoplasms0low110
Colorectal Cancer0low60
Colorectal Carcinoma0low60
Colorectal Neoplasms0low60
Colorectal Tumors0low60
Corneal Angiogenesis0low10
Corneal Neovascularization0low10
Coronary Restenosis0low10
Coronavirus Disease 20190medium74
Coronavirus Disease-190medium74
Coronavirus Infections0low20
COVID-190medium74
COVID-19 Pandemic0medium74
COVID-19 Pandemics0medium74
COVID-19 Virus Disease0medium74
COVID-19 Virus Infection0medium74
COVID190medium74
Deficiency, Oxygen0low20
Degenerative Diseases, Central Nervous System0low10
Degenerative Diseases, Nervous System0low10
Degenerative Diseases, Neurologic0low10
Degenerative Diseases, Spinal Cord0low10
Degenerative Neurologic Diseases0low10
Degenerative Neurologic Disorders0low10
Delayed Hemolytic Transfusion Reaction0low10
Delayed Serologic Transfusion Reaction0low10
Dementia, Alzheimer Type0low20
Dementia, Presenile0low20
Dementia, Primary Senile Degenerative0low20
Dementia, Senile0low20
Dementias, Transmissible0low10
Demineralization, Tooth0low10
Dental Abrasion0low10
Dermatitis, Actinic0low30
Dermatitis, Contact, Phototoxic0low20
Dermatitis, Phototoxic0low20
Dermatoses0low10
Dermatosis0low10
Diabetes Mellitus, Experimental0low10
Digestive System Cancer0low10
Digestive System Neoplasms0low10
Disease0low10
Disease Models, Animal0low120
Early Onset Alzheimer Disease0low20
EHS Tumor0low30
Electrolytes0low40
Encephalopathies, Spongiform, Transmissible0low10
Epithelial Neoplasms, Malignant0low40
Epithelial Tumors, Malignant0low40
Epithelioma0low40
ER-Negative PR-Negative HER2-Negative Breast Cancer0low30
ER-Negative PR-Negative HER2-Negative Breast Neoplasms0low30
Esophageal Cancer0low30
Esophageal Neoplasms0low30
Esophagus Cancer0low30
Esophagus Neoplasm0low30
Experimental Diabetes Mellitus0low10
Experimental Hepatoma0low20
Experimental Hepatomas0low20
Experimental Leukemia0low10
Experimental Leukemias0low10
Experimental Liver Neoplasms0low20
Experimental Lung Inflammation0low10
Experimental Mammary Neoplasms0low130
Experimental Melanoma0low50
Experimental Melanomas0low50
Experimental Neoplasms0low160
Experimental Sarcoma0low30
Experimental Sarcomas0low30
Extrahepatic Cholangiocarcinoma0low10
Extravascular Hemolysis0low120
Eye Diseases0low10
Eye Disorders0low10
Familial Alzheimer Disease (FAD)0low20
Fatty Streak, Arterial0low10
Febrile Non-Hemolytic Transfusion Reaction0low10
Fibroatheroma0low10
Fibroatheromatous Plaques0low10
Fibrosarcoma0low50
Fibrous Meningioma0low10
Focal Onset Alzheimer's Disease0low20
Fungal Diseases0low10
Fungal Infections0low10
Fungus Diseases0low10
Fungus Infections0low10
Gastric Cancer0low10
Gastric Cancer, Familial Diffuse0low10
Gastric Neoplasms0low10
Genome Instability0low10
Genome Stability0low10
Genomic Instability0low10
Genomic Stability0low10
Germinoblastoma0low20
Giant Cell Glioblastoma0low10
Glial Cell Tumors0low30
Glioblastoma0low10
Glioblastoma Multiforme0low10
Glioma0low30
Gram-Negative Bacterial Infections0low10
Group A Strep Infection0low10
Group A Streptococcal Infection0low10
Group A Streptococcal Infections0low10
Group B Strep Infection0low10
Group B Streptococcal Infection0low10
Group B Streptococcal Infections0low10
Haemolysis0low120
Harding Passey Melanoma0low50
Head and Neck Cancer0low20
Head and Neck Neoplasm0low20
Head and Neck Neoplasms0low20
Head Cancer0low20
Head Neoplasm0low20
Head Neoplasms0low20
Head, Neck Neoplasms0low20
Helicobacter Infections0low10
Hemangioblastic Meningioma0low10
Hemangiopericytic Meningioma0low10
Hemangiosarcoma0low10
Hemolysis0low120
Hemolytic Transfusion Reaction0low10
Hepatic Cancer0low60
Hepatic Neoplasms0low60
Hepatoblastoma0low10
Hepatocellular Cancer0low60
Hepatocellular Carcinoma0low40
Hepatoma0low40
Hepatoma, Experimental0low20
Hepatoma, Morris0low20
Hepatoma, Novikoff0low20
Hepatomas, Experimental0low20
HIV0low10
HIV Coinfection0low20
HIV Infections0low20
HTLV-III Infections0low20
HTLV-III-LAV Infections0low20
Human Mammary Carcinoma0low160
Human Transmissible Spongiform Encephalopathies, Inherited0low10
Hypomineralization, Tooth0low10
Hypotensive Transfusion Reaction0low10
Hypoxemia0low20
Hypoxia0low20
Idiopathic Parkinson Disease0low10
Idiopathic Parkinson's Disease0low10
Infection, Bacterial0low10
Infections, Bacterial0low10
Infections, Coronavirus0low20
Infections, Gram-Negative Bacterial0low10
Infections, Helicobacter0low10
Infections, Pseudomonas0low10
Infections, Soft Tissue0low10
Infections, Staphylococcal0low30
Infections, Streptococcal0low10
Inherited Human Transmissible Spongiform Encephalopathies0low10
Insulin Resistance0low10
Insulin Sensitivity0low10
Intracranial Meningioma0low10
Intracranial Neoplasms0low50
Intrahepatic Cholangiocarcinoma0low10
Intraocular Pressure0low20
Intraorbital Meningioma0low10
Intravascular Hemolysis0low120
Intraventricular Meningioma0low10
Kahler Disease0low10
Koch's Disease0low10
Kochs Disease0low10
Laryngeal Cancer0low10
Laryngeal Neoplasms0low10
Larynx Cancer0low10
Larynx Neoplasms0low10
Late Onset Alzheimer Disease0low20
Leg Ulcer0low10
Leishmaniasis, American0low20
Leishmaniasis, Cutaneous0low20
Leishmaniasis, New World0low20
Leishmaniasis, Old World0low20
Leukemia L 12100low10
Leukemia L12100low10
Leukemia Model, Animal0low10
Leukemia, Acute Lymphoblastic0low10
Leukemia, Experimental0low10
Leukemia, Lymphoblastic0low10
Leukemia, Lymphoblastic, Acute0low10
Leukemia, Lymphoblastic, Acute, L10low10
Leukemia, Lymphoblastic, Acute, L20low10
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive0low10
Leukemia, Lymphocytic0low10
Leukemia, Lymphocytic, Acute0low10
Leukemia, Lymphocytic, Acute, L10low10
Leukemia, Lymphocytic, Acute, L20low10
Leukemia, Lymphocytic, T Cell0low10
Leukemia, Lymphocytic, T-Cell0low10
Leukemia, Lymphoid0low10
Leukemia, Lymphoid, Acute0low10
Leukemia, T-Cell0low10
Leukemias, Experimental0low10
Lewy Body Parkinson Disease0low10
Lewy Body Parkinson's Disease0low10
Liver Cancer0low60
Liver Cancer, Adult0low40
Liver Cell Carcinoma0low40
Liver Cell Carcinoma, Adult0low40
Liver Neoplasms0low60
Liver Neoplasms, Experimental0low20
Lobar Pneumonia0low10
Local Neoplasm Recurrence0low10
Local Neoplasm Recurrences0low10
Locoregional Neoplasm Recurrence0low10
Lung Adenocarcinoma0low10
Lung Cancer0low70
Lung Inflammation0low10
Lung Neoplasms0low70
Lymph Node Metastasis0low10
Lymphatic Metastasis0low10
Lymphoblastic Leukemia0low10
Lymphoblastic Leukemia, Acute0low10
Lymphoblastic Leukemia, Acute, Adult0low10
Lymphoblastic Leukemia, Acute, Childhood0low10
Lymphoblastic Leukemia, Acute, L10low10
Lymphoblastic Leukemia, Acute, L20low10
Lymphoblastic Lymphoma0low10
Lymphocytic Leukemia0low10
Lymphocytic Leukemia, Acute0low10
Lymphocytic Leukemia, L10low10
Lymphocytic Leukemia, L20low10
Lymphocytic Leukemia, T-Cell0low10
Lymphoid Leukemia0low10
Lymphoma0low20
Lymphoma, Lymphoblastic0low10
Lymphoma, Malignant0low20
Macular Degeneration0low10
Macular Degeneration, Age-Related0low10
Macular Dystrophy0low10
Maculopathies, Age-Related0low10
Maculopathy0low10
Maculopathy, Age-Related0low10
Malignancy0medium631
Malignant Epithelial Neoplasms0low40
Malignant Glioma0low30
Malignant Melanoma0low110
Malignant Meningioma0low10
Malignant Neoplasm of Breast0low160
Malignant Neoplasms0medium631
Malignant Neoplasms, Brain0low50
Malignant Primary Brain Neoplasms0low50
Malignant Primary Brain Tumors0low50
Malignant Tumor of Breast0low160
Malignant Tumor of Urinary Bladder0low50
Mammary Cancer0low160
Mammary Carcinoma, Animal0low10
Mammary Carcinoma, Human0low160
Mammary Neoplasm, Human0low160
Mammary Neoplasms0low10
Mammary Neoplasms, Animal0low10
Mammary Neoplasms, Experimental0low130
Mammary Neoplasms, Human0low160
Mastitis, Bovine0low10
Melanoma0low110
Melanoma, B160low50
Melanoma, Cloudman S910low50
Melanoma, Experimental0low50
Melanoma, Harding-Passey0low50
Melanomas, Experimental0low50
Meningioma0low10
Meningiomas, Multiple0low10
Meningiomatosis0low10
Meningotheliomatous Meningioma0low10
MERS (Middle East Respiratory Syndrome)0low20
Microcalcification0low20
Microcalcinosis0low20
Microcystic Meningioma0low10
Middle East Respiratory Syndrome0low20
Mixed Glioma0low30
Multiple Myeloma0low10
Mycobacterium tuberculosis Infection0low10
Mycoses0low10
Myeloma-Multiple0low10
Myeloma, Multiple0low10
Myeloma, Plasma-Cell0low10
Myelomatosis0low10
Nail Fungus0medium11
Nasopharyngeal Cancer0low30
Nasopharyngeal Carcinoma0low20
Nasopharyngeal Neoplasms0low30
Nasopharynx Cancer0low30
Nasopharynx Neoplasms0low30
Neck Cancer0low20
Neck Neoplasm0low20
Neck Neoplasms0low20
Necrosis0low60
Neoplasia0medium631
Neoplasm0medium631
Neoplasm Recurrence, Local0low10
Neoplasm Recurrence, Locoregional0low10
Neoplasm Recurrences, Local0low10
Neoplasms0medium631
Neoplasms, Benign0medium631
Neoplasms, Bladder0low50
Neoplasms, Brain0low50
Neoplasms, Brain, Benign0low50
Neoplasms, Brain, Malignant0low50
Neoplasms, Brain, Primary0low50
Neoplasms, Breast0low160
Neoplasms, Cervical0low40
Neoplasms, Cervix0low40
Neoplasms, Colonic0low110
Neoplasms, Colorectal0low60
Neoplasms, Digestive System0low10
Neoplasms, Esophageal0low30
Neoplasms, Experimental0low160
Neoplasms, Experimental Liver0low20
Neoplasms, Experimental Mammary0low130
Neoplasms, Gastric0low10
Neoplasms, Head0low20
Neoplasms, Head and Neck0low20
Neoplasms, Hepatic0low60
Neoplasms, Intracranial0low50
Neoplasms, Laryngeal0low10
Neoplasms, Liver0low60
Neoplasms, Lung0low70
Neoplasms, Malignant Epithelial0low40
Neoplasms, Mammary0low10
Neoplasms, Nasopharyngeal0low30
Neoplasms, Neck0low20
Neoplasms, Ovarian0low60
Neoplasms, Pancreatic0low30
Neoplasms, Prostate0low50
Neoplasms, Prostatic0low50
Neoplasms, Pulmonary0low70
Neoplasms, Skin0low70
Neoplasms, Stomach0low10
Neoplasms, Upper Aerodigestive Tract0low20
Neovascularization, Pathologic0low10
Neovascularization, Pathological0low10
Nervous System Degenerative Diseases0low10
Neuritic Plaques0low10
Neuroblastoma0low30
Neurodegenerative Diseases0low10
Neurodegenerative Disorders0low10
Neurologic Degenerative Conditions0low10
Neurologic Degenerative Diseases0low10
Neurologic Diseases, Degenerative0low10
Olfactory Groove Meningioma0low10
Onychomycosis0medium11
Oriental Sore0low20
Ovarian Cancer0low60
Ovarian Neoplasms0low60
Ovary Cancer0low60
Ovary Neoplasms0low60
Oxygen Deficiency0low20
Pancreas Cancer0low30
Pancreas Neoplasms0low30
Pancreatic Cancer0low30
Pancreatic Neoplasms0low30
Papillary Meningioma0low10
Paralysis Agitans0low10
Parasagittal Meningioma0low10
Parasitemia0low10
Parkinson Disease0low10
Parkinson Disease, Idiopathic0low10
Parkinson's Disease0low10
Parkinson's Disease, Idiopathic0low10
Parkinson's Disease, Lewy Body0low10
Pathologic Angiogenesis0low10
Pathologic Calcification0low20
Pathologic Neovascularization0low10
Periodontitis, Adult0medium11
Periodontitis, Chronic0medium11
Peritoneal Carcinomatosis0low10
Peritoneal Neoplasms0low10
Peritoneal Surface Malignancy0low10
Photodermatitis0low30
Photosensitivity Disorders0low30
Photosensitization0low30
Phototoxic Contact Dermatitis0low20
Phototoxic Dermatitis0low20
Phototoxicity0low20
Plaque, Amyloid0low10
Plaque, Atherosclerotic0low10
Plaques, Amyloid0low10
Plasma Cell Myeloma0low10
Pneumonia0low10
Pneumonia, Lobar0low10
Pneumonia, Viral0low20
Pneumonitis0low10
Post-Transfusion Purpura0low10
Posterior Fossa Meningioma0low10
Posttransfusion Purpura0low10
Precordial Catch0medium22
Precordial Catch Syndrome0medium22
Precursor Cell Lymphoblastic Leukemia-Lymphoma0low10
Presenile Alzheimer Dementia0low20
Primary Brain Neoplasms0low50
Primary Malignant Brain Neoplasms0low50
Primary Malignant Brain Tumors0low50
Primary Parkinsonism0low10
Primary Senile Degenerative Dementia0low20
Prion Disease0low10
Prion Diseases0low10
Prion Protein Diseases0low10
Prion-Associated Disorders0low10
Prion-Induced Disorder0low10
Prion-Induced Disorders0low10
Prostate Cancer0low50
Prostate Neoplasms0low50
Prostatic Cancer0low50
Prostatic Neoplasms0low50
Psammomatous Meningioma0low10
Pseudomonas aeruginosa Infection0low10
Pseudomonas Infections0low10
Pulmonary Cancer0low70
Pulmonary Inflammation0low10
Pulmonary Neoplasms0low70
Pus0low10
Recurrence, Local Neoplasm0low10
Recurrence, Locoregional Neoplasm0low10
Recurrences, Local Neoplasm0low10
Reticulolymphosarcoma0low20
Retinal Detachment0low10
Retinal Pigment Epithelial Detachment0low10
Sarcoma0low10
Sarcoma, Engelbreth-Holm-Swarm0low30
Sarcoma, Epithelioid0low10
Sarcoma, Experimental0low30
Sarcoma, Germinoblastic0low20
Sarcoma, Jensen0low30
Sarcoma, Soft Tissue0low10
Sarcoma, Spindle Cell0low10
Sarcomas, Experimental0low30
SARS Coronavirus 2 Infection0medium74
SARS-CoV-2 Infection0medium74
Secretory Meningioma0low10
Senile Dementia, Acute Confusional0low20
Senile Dementia, Alzheimer Type0low20
Senile Plaques0low10
Sensitivity and Specificity0medium141
Skin and Subcutaneous Tissue Disorders0low10
Skin Cancer0low70
Skin Diseases0low10
Skin Neoplasms0low70
Soft Tissue Infections0low10
Sphenoid Wing Meningioma0low10
Spinal Meningioma0low10
Spongiform Encephalopathies, Transmissible0low10
Squamous Cell Carcinoma0low20
Staphylococcal Infections0low30
Staphylococcus aureus Infection0low30
Stasis Ulcer0low10
Stomach Cancer0low10
Stomach Neoplasms0low10
Streptococcal Infections0low10
Streptozocin Diabetes0low10
Streptozotocin Diabetes0low10
Suppuration0low10
T Lymphocytic Leukemia0low10
T-Cell Leukemia0low10
T-Lymphocytic Leukemia0low10
T-Lymphotropic Virus Type III Infections, Human0low20
TAGHD0low10
Texidor's Twinge0medium22
Thrombosis0low10
Thrombus0low10
Tinea Unguium0medium11
Tooth Abrasion0low10
Tooth Demineralization0low10
Tooth Discoloration0low10
Tooth Hypomineralization0low10
Transfusion Reaction0low10
Transfusion-Associated Allergic Reaction0low10
Transfusion-Associated Circulatory Overload0low10
Transfusion-Associated Dyspnea0low10
Transfusion-Associated Graft Vs. Host Disease0low10
Transfusion-Transmitted Infection0low10
Transitional Meningioma0low10
Transmissible Dementias0low10
Transmissible Spongiform Encephalopathies0low10
Triple Negative Breast Cancer0low30
Triple Negative Breast Neoplasms0low30
Triple-Negative Breast Cancer0low30
Triple-Negative Breast Neoplasm0low30
Trypanosoma cruzi Infection0low10
Trypanosomiasis, South American0low10
Tuberculosis0low10
Tumors0medium631
Tumors, Breast0low160
UADT Neoplasm0low20
UADT Neoplasms0low20
Upper Aerodigestive Tract Neoplasm0low20
Upper Aerodigestive Tract Neoplasms0low20
Urinary Bladder Cancer0low50
Urinary Bladder Neoplasms0low50
Uterine Cervical Cancer0low40
Uterine Cervical Neoplasms0low40
Varicose Ulcer0low10
Venous Hypertension Ulcers0low10
Venous Stasis Ulcers0low10
Venous Ulcer0low10
Viral Diseases0low10
Viral Infections0low10
Viremia0low10
Virus Diseases0low10
Virus Infections0low10
Xanthomatous Meningioma0low10

Research Highlights

Safety/Toxicity (16)

ArticleYear
A pH-sensitive nanoagent self-assembled from a highly negatively-charged phthalocyanine with excellent biosafety for photothermal therapy.
Journal of materials chemistry. B, 03-28, Volume: 9, Issue: 12		2021
Supramolecular subphthalocyanine complexes-cellular uptake and phototoxicity.
Chemical communications (Cambridge, England), Jul-09, Volume: 56, Issue: 55		2020
Phototoxic effect of aluminium-chlorine and aluminium-hydroxide phthalocyanines on Leishmania (l.) amazonensis.
Photodiagnosis and photodynamic therapy, Volume: 21		2018
An effective and potentially safe blood disinfection protocol using tetrapyrrolic photosensitizers.
Future medicinal chemistry, Volume: 9, Issue: 4		2017
The quest for biocompatible phthalocyanines for molecular imaging: Photophysics, relaxometry and cytotoxicity studies.
Journal of inorganic biochemistry, Volume: 154		2016
Evaluation of oxygen dependence on in vitro and in vivo cytotoxicity of photoimmunotherapy using IR-700-antibody conjugates.
Free radical biology & medicine, Volume: 85		2015
Toxicity of imine-iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects.
Journal of applied toxicology : JAT, Volume: 34, Issue: 8		2014
Phthalocyanines functionalized with 2-methyl-5-nitro-1H-imidazolylethoxy and 1,4,7-trioxanonyl moieties and the effect of metronidazole substitution on photocytotoxicity.
Journal of inorganic biochemistry, Volume: 127		2013
A nano complex of hydrophilic phthalocyanine and polyethylenimine for improved cellular internalization efficiency and phototoxicity.
Colloids and surfaces. B, Biointerfaces, Jan-01, Volume: 101		2013
The toxicity of phthalocyanines to the aquatic plant Lemna minor (duckweed) - testing of 31 compounds.
Chemosphere, Volume: 88, Issue: 8		2012
In search of the main properties of phthalocyanines participating in toxicity against cyanobacteria.
Chemosphere, Volume: 77, Issue: 11		2009
Phthalocyanine tetrasulfonates affect the amyloid formation and cytotoxicity of alpha-synuclein.
Biochemistry, Mar-30, Volume: 43, Issue: 12		2004
ESR studies of a series of phthalocyanines. Mechanism of phototoxicity. Comparative quantitation of O2-. using ESR spin-trapping and cytochrome c reduction techniques.
Free radical research, Volume: 28, Issue: 5		1998
Subcellular distribution and photocytotoxicity of aluminium phthalocyanines and haematoporphyrin derivative in cultured human meningioma cells.
British journal of neurosurgery, Volume: 10, Issue: 1		1996
Role of oxygen in the phototoxicity of phthalocyanines.
International journal of radiation biology, Volume: 67, Issue: 1		1995
Photochemical generation of superoxide radical and the cytotoxicity of phthalocyanines.
International journal of radiation biology and related studies in physics, chemistry, and medicine, Volume: 48, Issue: 5		1985
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Determination of photocyanine in human serum by HPLC and application to pharmacokinetic study.
Journal of chromatographic science, Volume: 52, Issue: 8		2014
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (3)

ArticleYear
Porphyrin Derivative Nanoformulations for Therapy and Antiparasitic Agents.
Molecules (Basel, Switzerland), Apr-29, Volume: 25, Issue: 9		2020
Enhanced photodynamic efficacy of zinc phthalocyanine by conjugating to heptalysine.
Bioconjugate chemistry, Nov-21, Volume: 23, Issue: 11		2012
Nanoparticles improve biological functions of phthalocyanine photosensitizers used for photodynamic therapy.
Current drug metabolism, Volume: 13, Issue: 8		2012
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (9)

ArticleYear
A Cationic Gallium Phthalocyanine Inhibits Amyloid β Peptide Fibril Formation.
Current Alzheimer research, Volume: 17, Issue: 7		2020
Near-infrared photoimmunotherapy: a comparison of light dosing schedules.
Oncotarget, May-23, Volume: 8, Issue: 21		2017
Phthalocyanine-loaded graphene nanoplatform for imaging-guided combinatorial phototherapy.
International journal of nanomedicine, Volume: 10		2015
Photoassisted Fenton degradation of phthalocyanine dyes from wastewater of printing industry using Fe(II)/γ-Al2O3 catalyst in up-flow fluidized-bed.
Journal of environmental sciences (China), Jun-01, Volume: 26, Issue: 6		2014
Investigating the efficiency of novel metallo-phthalocyanine PDT-induced cell death in MCF-7 breast cancer cells.
Photodiagnosis and photodynamic therapy, Volume: 9, Issue: 3		2012
Effective use of molecular recognition in gas sensing: results from acoustic wave and in situ FT-IR measurements.
Analytical chemistry, Aug-01, Volume: 71, Issue: 15		1999
Optimum properties of injectable test solutions for intrathecal administration to conscious rats.
The Journal of veterinary medical science, Volume: 59, Issue: 12		1997
Selective necrosis in dimethylhydrazine-induced rat colon tumors using phthalocyanine photodynamic therapy.
Gastroenterology, Volume: 98, Issue: 6		1990
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Natural Sources (1)

ArticleYear
Lesson from Nature: Biomimetic Self-Assembling Phthalocyanines for High-Efficient Photothermal Therapy within the Biological Transparent Window.
ACS applied materials & interfaces, Jan-30, Volume: 11, Issue: 4		2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]