Proteins > heat shock protein 90
Page last updated: 2024-08-07 12:33:13

heat shock protein 90

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (97)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
1,10-phenanthrolineCandida albicansEC5010.463010
clotrimazoleCandida albicansEC5050.570330
flucytosineCandida albicansEC50106.903730
hexachloropheneCandida albicansEC501.725010
cordycepinCandida albicansEC50150.000010
nitroxolineCandida albicansEC500.681010
desferrioxamine b mesylateCandida albicansEC50112.681830
neocuproineCandida albicansEC50100.333030
dimidium bromideCandida albicansEC50160.000010
2,2',2''-terpyridineCandida albicansEC500.521010
jatrorrhizineCandida albicansEC50160.000010
9-methoxyellipticineCandida albicansEC501.439010
4-(2-thiazolylazo)resorcinolCandida albicansEC5016.706030
2-methyl-4-nitroquinoline 1-oxideCandida albicansEC500.195010
pyridabenCandida albicansEC50106.774730
diphyllinCandida albicansEC502.212010
enniatin bCandida albicansEC50150.000010
(R)-RoemerineCandida albicansEC50150.000010
anisomycinCandida albicansEC501.481010
1-[(4-methoxyphenyl)-oxomethyl]-2H-quinoline-2-carbonitrileCandida albicansEC50100.585030
epiandrosteroneCandida albicansEC505.650010
solasodineCandida albicansEC50120.033030
mupirocinCandida albicansEC50150.000010
cgp 60474Candida albicansEC500.939010
1-(3,4-dihydro-2H-quinolin-1-yl)-2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)thio]ethanoneCandida albicansEC50160.000010
N-(1,3-benzodioxol-5-yl)-N-[1-(4-chlorophenyl)-2-(cyclohexylamino)-2-oxoethyl]-2-pyrazinecarboxamideCandida albicansEC509.718010
N-[7-(2-chlorophenyl)-5-(4-methoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methoxyacetamideCandida albicansEC50160.000010
N2-(4-fluorophenyl)-6-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1,3,5-triazine-2,4-diamineCandida albicansEC5030.801010
2-[(4-chloro-2-methylphenoxy)methyl]imidazo[1,2-a]pyrimidineCandida albicansEC505.340010
4-(3-chlorophenyl)thiosemicarbazideCandida albicansEC508.449010
1-(4-methoxyphenyl)-3-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ureaCandida albicansEC502.741010
2-(3-methyl-2-oxo-1-benzimidazolyl)acetonitrileCandida albicansEC5014.759010
N-(2-chlorophenyl)-5-nitro-2-furancarboxamideCandida albicansEC500.693010
2-[(3-fluorophenyl)methylthio]pyrimidine-4,6-diamineCandida albicansEC50150.000010
2-[(5-bromo-2-thiophenyl)sulfonylamino]-N-(2-furanylmethyl)benzamideCandida albicansEC50160.000010
4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acidCandida albicansEC503.348010
N2-tert-butyl-N6-ethyl-N4-propan-2-yl-1,3,5-triazine-2,4,6-triamineCandida albicansEC50107.133730
(4-chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanoneCandida albicansEC50100.287730
2-[[[3-methyl-4-[[2-(3-nitrophenoxy)-1-oxoethyl]amino]phenyl]-oxomethyl]amino]benzoic acidCandida albicansEC505.272010
4-[(3-methylphenyl)thio]-2-phenyl-5-pyrimidinecarboxylic acidCandida albicansEC50150.000010
3,4-dichloro-N-(4-chloro-3-methyl-5-isoxazolyl)benzamideCandida albicansEC50150.000010
N-(4-acetamidophenyl)-4-(1,3-dioxo-2-isoindolyl)butanamideCandida albicansEC50150.000010
2-[2-[[1-oxo-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]ethyl]amino]-4-thiazolyl]acetic acid ethyl esterCandida albicansEC5058.358730
4-methyl-N-[(1-oxopentylhydrazo)-sulfanylidenemethyl]benzamideCandida albicansEC507.759010
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[methyl-(phenylmethyl)sulfamoyl]benzamideCandida albicansEC500.291010
4-[4-(phenylmethyl)-1-piperidinyl]thieno[2,3-d]pyrimidineCandida albicansEC5060.356030
3,5-dimethyl-4-isoxazolecarboxylic acid [2-(4-amino-1-methyl-2,6-dioxo-3-propyl-5-pyrimidinyl)-2-oxoethyl] esterCandida albicansEC50150.000010
4-[ethyl-(phenylmethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamideCandida albicansEC5056.665330
2-[2-[[3-(1,3-benzoxazol-2-yl)anilino]-oxomethyl]phenyl]benzoic acidCandida albicansEC50113.060030
2-methoxy-4-(methylthio)benzoic acid [2-(cyclopropylamino)-2-oxoethyl] esterCandida albicansEC50150.000010
2-(2,3-dihydro-1H-inden-5-yloxy)-1-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethanoneCandida albicansEC50160.000010
4-bromo-N-[3-oxo-3-(2-thiazolylamino)propyl]benzamideCandida albicansEC50150.000010
2-amino-6-[4-(6-chloro-2-pyridinyl)-1-piperazinyl]pyridine-3,5-dicarbonitrileCandida albicansEC5058.422730
1-[(4-chlorophenyl)-oxomethyl]-5-hydroxy-5-phenyl-4H-pyrazole-3-carboxylic acid methyl esterCandida albicansEC50160.000010
N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamideCandida albicansEC501.936010
N-[1-oxo-3-phenyl-1-(2-pyridinylmethylamino)propan-2-yl]-2-furancarboxamideCandida albicansEC50150.000010
N-[2-(1-phenylethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]methanesulfonamideCandida albicansEC50160.000010
cb 7969312Candida albicansEC500.930010
7-[[[1-(3-methylphenyl)-2-benzimidazolyl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinoneCandida albicansEC50150.000010
2-[(3-cyano-4,6-diphenyl-2-pyridinyl)thio]-3-methylbutanoic acidCandida albicansEC503.768010
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamideCandida albicansEC5038.960750
3-(benzenesulfonyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]propanamideCandida albicansEC50160.000010
N-[2-(cyclohexylamino)-2-oxo-1-(6-quinolinyl)ethyl]-N-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamideCandida albicansEC50150.000010
6-[(2-chloro-4-fluorophenyl)methyl]-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl esterCandida albicansEC500.755010
N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-2-(3-oxo-1,4-benzoxazin-4-yl)acetamideCandida albicansEC50150.000010
7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinolCandida albicansEC501.457010
2-(3-phenyl-1-indazolyl)acetic acid methyl esterCandida albicansEC5062.044730
3-(phenoxymethyl)-2-benzofurancarboxylic acid (1-amino-1-oxopropan-2-yl) esterCandida albicansEC50160.000010
2-phenoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]acetamideCandida albicansEC500.727010
5-chloro-7-[(4-ethyl-1-piperazinyl)-(3-pyridinyl)methyl]-8-quinolinolCandida albicansEC5055.537730
2-[(2,2-dimethyl-4-oxo-3,4-dihydro-2H-1-benzopyran-6-yl)oxy]-N-heptylacetamideCandida albicansEC50107.033730
2-[(4-chlorophenyl)methylthio]-N-(2-hydroxy-5-nitrophenyl)acetamideCandida albicansEC50150.000010
3-ethyl-2-sulfanylidene-5-thiophen-2-yl-1H-thieno[2,3-d]pyrimidin-4-oneCandida albicansEC50160.000010
7-chloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4-quinazolinoneCandida albicansEC5012.080730
5-methyl-2-[[(4-nitrophenyl)-oxomethyl]hydrazo]-4-thiazolecarboxylic acid ethyl esterCandida albicansEC500.981010
6-nitro-3-phenyl-1H-benzimidazole-2-thioneCandida albicansEC500.648010
2,4-dichloro-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]benzamideCandida albicansEC503.744350
2-[[5-[(4-fluorophenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-N-(3-sulfamoylphenyl)acetamideCandida albicansEC50160.000010
1-(5-chloro-2,4-dimethoxyphenyl)-3-(phenylmethyl)thioureaCandida albicansEC5024.984010
2,5-dichloro-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamideCandida albicansEC5056.380330
terbinafine hydrochlorideCandida albicansEC502.591010
su 9516Candida albicansEC50120.312530
cycloheterophyllinCandida albicansEC5012.991010
(2R)-2-[[(2R,3R,4R)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-2-[(2S,3R,4S,5S)-5-(2,4-dioxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]acetic acidCandida albicansEC503.162010
5233705 compoundCandida albicansEC5010.271030
chlorhexidineCandida albicansEC50100.709330
a 77636Candida albicansEC503.364010
4-methoxybenzoic acid [2-(4-bromophenyl)-4-oxo-3-quinazolinyl] esterCandida albicansEC501.106010
chlorhexidine hydrochlorideCandida albicansEC5083.678030
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-4-nitro-3-isoxazolecarboxamideCandida albicansEC500.989010
[3-(1-methyl-2-pyrrolyl)-1H-pyrazol-5-yl]-[1-(2-pyridinyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]methanoneCandida albicansEC500.741010
4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-[[3-(trifluoromethyl)phenyl]methyl]piperidineCandida albicansEC508.133010
dafadine DCandida albicansEC502.543010
LSM-23565Candida albicansEC50150.000010
1-ethyl-4-hydroxy-2-oxo-N-(3-pyridinylmethyl)-3-quinolinecarboxamideCandida albicansEC509.525010
4-chloro-N-[(4-chlorophenyl)methyl]-3-nitro-1H-pyrazole-5-carboxamideCandida albicansEC50160.000010
3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-6-(phenylmethyl)-2H-1,2,4-triazin-5-oneCandida albicansEC50160.000010