midodrine has been researched along with Sensitivity and Specificity in 6 studies
Midodrine: An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
midodrine : An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-(glycylamino)-1-hydroxyethyl group. A direct-acting sympathomimetic with selective alpha-adrenergic agonist activity, it is used (generally as its hydrochloride salt) as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the use of erythrocytic hydrogen sulfide (H2S) in predicting the therapeutic efficacy of midodrine hydrochloride for children with postural orthostatic tachycardia syndrome (POTS)." | 7.79 | Postural orthostatic tachycardia syndrome with increased erythrocytic hydrogen sulfide and response to midodrine hydrochloride. ( Chen, S; Du, J; Du, S; Fu, C; Jin, H; Li, X; Liu, D; Tang, C; Yang, J; Zhao, J, 2013) |
| "To evaluate the use of erythrocytic hydrogen sulfide (H2S) in predicting the therapeutic efficacy of midodrine hydrochloride for children with postural orthostatic tachycardia syndrome (POTS)." | 3.79 | Postural orthostatic tachycardia syndrome with increased erythrocytic hydrogen sulfide and response to midodrine hydrochloride. ( Chen, S; Du, J; Du, S; Fu, C; Jin, H; Li, X; Liu, D; Tang, C; Yang, J; Zhao, J, 2013) |
| "Midodrine may have treatment effects on cirrhotic ascites." | 2.53 | Effects of midodrine in patients with ascites due to cirrhosis: Systematic review and meta-analysis. ( Cheng, G; Guo, TT; Liu, ZX; Ren, Y; Song, Y; Yang, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omar, MA | 1 |
| Nagy, DM | 1 |
| Halim, ME | 1 |
| Yang, J | 1 |
| Zhao, J | 2 |
| Du, S | 1 |
| Liu, D | 1 |
| Fu, C | 1 |
| Li, X | 1 |
| Chen, S | 1 |
| Tang, C | 2 |
| Du, J | 2 |
| Jin, H | 2 |
| Guo, TT | 1 |
| Yang, Y | 1 |
| Song, Y | 1 |
| Ren, Y | 1 |
| Liu, ZX | 1 |
| Cheng, G | 1 |
| Barth, T | 1 |
| Pupo, MT | 1 |
| Borges, KB | 1 |
| Okano, LT | 1 |
| Bonato, PS | 1 |
| Yoshida, H | 1 |
| Ohno, Y | 1 |
| Yoshikuni, K | 1 |
| Todoroki, K | 1 |
| Nohta, H | 1 |
| Yamaguchi, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Adding Hypertonic Saline Solutions and/or Etilefrine to Standard Diuretics Therapy in Egyptian Cirrhotic Patients With Ascites[NCT04785755] | Phase 2 | 90 participants (Actual) | Interventional | 2017-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for midodrine and Sensitivity and Specificity
| Article | Year |
|---|---|
Effects of midodrine in patients with ascites due to cirrhosis: Systematic review and meta-analysis.
Topics: Bias; Data Interpretation, Statistical; Humans; Liver Cirrhosis; Midodrine; Sensitivity and Specific | 2016 |
5 other studies available for midodrine and Sensitivity and Specificity
| Article | Year |
|---|---|
The convenient use of fluorescamine for spectrofluorimetric determination of midodrine hydrochloride in pure form and its tablets formulation: Application to content uniformity testing.
Topics: Buffers; Calibration; Fluorescamine; Hydrogen-Ion Concentration; Indicators and Reagents; Limit of D | 2019 |
Postural orthostatic tachycardia syndrome with increased erythrocytic hydrogen sulfide and response to midodrine hydrochloride.
Topics: Area Under Curve; Case-Control Studies; Child; Child, Preschool; Electrocardiography; Erythrocytes; | 2013 |
Plasma copeptin and therapeutic effectiveness of midodrine hydrochloride on postural tachycardia syndrome in children.
Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Biomarkers; Child; Child, Preschool; Female; Glyco | 2014 |
Stereoselective determination of midodrine and desglymidodrine in culture medium: application to a biotransformation study employing endophytic fungi.
Topics: Ascomycota; Asteraceae; Culture Media; Electrophoresis, Capillary; Linear Models; Midodrine; Reprodu | 2010 |
Determination of midodrine in human plasma by high-performance liquid chromatography with fluorescence detection.
Topics: Adrenergic alpha-Agonists; Adult; Chromatography, High Pressure Liquid; Fluorescence; Humans; Male; | 2003 |