Page last updated: 2024-12-07

1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate monohydrate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

That's a mouthful! You're describing a complex organic molecule with the chemical name: **1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1H-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate monohydrate.**

Let's break it down:

* **1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1H-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid:** This is the core molecule. It's a quinoline derivative (a nitrogen-containing heterocyclic compound) with several substituents, including a cyclopropyl group, a difluoromethoxy group, and a 1-methyl-2,3-dihydro-1H-5-isoindolyl group.
* **methanesulfonate:** This is a salt form of the molecule. Methanesulfonate (CH3SO3-) is an anion that's commonly used to form salts with organic compounds.
* **monohydrate:** This indicates that the molecule has one molecule of water associated with it.

**Importance for Research:**

This molecule, and similar compounds, are often investigated in drug discovery and development research. This is because they have been shown to possess interesting biological activities, particularly in the following areas:

* **Anti-cancer activity:** These compounds might target specific proteins or pathways involved in cancer cell growth and proliferation.
* **Anti-inflammatory activity:** They may inhibit enzymes or signaling pathways associated with inflammation.
* **Antibacterial activity:** Some compounds in this class exhibit antibacterial properties, potentially targeting bacterial enzymes or processes.

**However, it's crucial to understand that:**

* **Specific activity and applications:** Without further context, it's impossible to know the precise activity of this specific molecule. Research papers or patents would provide more information.
* **Ongoing research:** Drug discovery is an iterative process. Many compounds are synthesized and tested, and only a small fraction eventually make it to clinical trials.
* **Safety and efficacy:** The safety and effectiveness of any drug candidate must be rigorously assessed before it can be used in humans.

Therefore, the importance of this specific molecule for research depends on its exact biological activity and the stage of development it is in.

T 3811ME: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID124094
SCHEMBL ID1649428
MeSH IDM0304708

Synonyms (24)

Synonym
bms 284756
3-quinolinecarboxylic acid, 1-cyclopropyl-8-(difluoromethoxy)-7-((1r)-2,3-dihydro-1-methyl-1h-isoindol-5-yl)-1,4-dihydro-4-oxo-, monomethanesulfonate
bms 284756-01
223652-82-2
3-quinolinecarboxylic acid, 1-cyclopropyl-8-(difluoromethoxy)-7-((1r)-2,3-dihydro-1-methyl-1h-isoindol-5-yl)-1,4-dihydro-4-oxo-, monomethanesulfonate
1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate monohydrate
unii-437zku48cf
t 3811me
437zku48cf ,
(r)-1-cyclopropyl-8-difluoromethoxy-7-(1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate
(r)-1-cyclo-propyl-8-difluoromethoxy-7-(1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate
garenoxacin mesilate [who-dd]
(r)-1-cyclopropyl-8-(difluoromethoxy)-7-(1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid methanesulfonate
garenoxacin methanesulfonate [mi]
garenoxacin mesilate [mart.]
1-cyclopropyl-8-(difluoromethoxy)-7-((1r)-1-methyl-2,3-dihydro-1h-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid mesylate
(+)-garenoxacin mesylate anhydrous
3-quinolinecarboxylic acid, 1-cyclopropyl-8-(difluoromethoxy)-7-((1r)-2,3-dihydro-1-methyl-1h-isoindol-5-yl)-1,4-dihydro-4-oxo-, methanesulfonate (1:1)
SCHEMBL1649428
DTXSID4058732
BCP17552
Q27258626
1-cyclopropyl-8-(difluoromethoxy)-7-[(1r)-1-methyl-2,3-dihydro-1h-isoindol-5-yl]-4-oxoquinoline-3-carboxylic acid;methanesulfonic acid
AKOS040759264
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's5 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.99

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.99 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.94 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.99)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (33.33%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (66.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]