Page last updated: 2024-08-07 14:47:11
Histidine decarboxylase
A histidine decarboxylase that is encoded in the genome of rat. [OMA:P16453, PRO:DNx]
Synonyms
HDC;
EC 4.1.1.22
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (9)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| methotrexate | Rattus norvegicus (Norway rat) | IC50 | 0.0014 | 1 | 1 |
| 5,8-dideazaisofolic acid | Rattus norvegicus (Norway rat) | IC50 | 22.0000 | 1 | 1 |
| cb 3705 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| (5)n,(8)n-deaza-(10)-n-methylfolate | Rattus norvegicus (Norway rat) | IC50 | 0.4300 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| nalorphine | Rattus norvegicus (Norway rat) | EC50 | 0.0015 | 1 | 1 |
| naloxone | Rattus norvegicus (Norway rat) | EC50 | 0.0015 | 1 | 1 |
| oxymorphone | Rattus norvegicus (Norway rat) | EC50 | 0.0010 | 1 | 1 |
| morphine | Rattus norvegicus (Norway rat) | EC50 | 0.0030 | 1 | 1 |
| naltrexone | Rattus norvegicus (Norway rat) | EC50 | 0.0005 | 1 | 1 |