A C-type lectin domain family 4 member M that is encoded in the genome of human. [PRO:WCB, UniProtKB:Q9H2X3]
Target | Category | Definition |
virus receptor activity | molecular function | Combining with a virus component and mediating entry of the virus into the cell. [GOC:bf, GOC:dph, PMID:7621403, UniProtKB-KW:KW-1183] |
protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
carbohydrate binding | molecular function | Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah] |
ICAM-3 receptor activity | molecular function | Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues. [GOC:ai, GOC:signaling, ISBN:0198506732, PMID:7515813] |
signaling receptor activity | molecular function | Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. [GOC:bf, GOC:signaling] |
peptide antigen binding | molecular function | Binding to an antigen peptide. [GOC:add, GOC:jl, GOC:rv] |
virion binding | molecular function | Binding to a virion, either by binding to components of the capsid or the viral envelope. [GOC:ai] |
metal ion binding | molecular function | Binding to a metal ion. [GOC:ai] |
calcium-dependent protein binding | molecular function | Binding to a protein or protein complex in the presence of calcium. [GOC:jid, PMID:10485905] |
mannose binding | molecular function | Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans. [GOC:jl, ISBN:0192800981] |
Target | Category | Definition |
adaptive immune response | biological process | An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149] |
leukocyte cell-cell adhesion | biological process | The attachment of a leukocyte to another cell via adhesion molecules. [GOC:go_curators] |
cell-cell recognition | biological process | Cell recognition between cells. May involve the formation of specialized cell junctions. [ISBN:0824072820] |
virion attachment to host cell | biological process | The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection. [GOC:bf, GOC:jl, UniProtKB-KW:KW-1161, VZ:956] |
receptor-mediated endocytosis of virus by host cell | biological process | Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell. [GOC:bf, GOC:jl, ISBN:0781702534] |
viral genome replication | biological process | Any process involved directly in viral genome replication, including viral nucleotide metabolism. [ISBN:0781702534] |
antigen processing and presentation | biological process | The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] |
intracellular signal transduction | biological process | The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] |
innate immune response | biological process | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu] |
symbiont entry into host cell | biological process | The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell. [GOC:jl] |
receptor-mediated virion attachment to host cell | biological process | The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface. [ISBN:0879694971] |
peptide antigen transport | biological process | The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. [GOC:add, ISBN:0781735149, PMID:15771591] |
intracellular transport of virus | biological process | The directed movement of a virus, or part of a virus, within the host cell. [GOC:ai, GOC:bf, GOC:jl, PMID:11733033] |
immune response | biological process | Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. [GO_REF:0000022, GOC:add] |
biological process involved in interspecies interaction between organisms | biological process | Any process evolved to enable an interaction with an organism of a different species. [GOC:cc] |