adefovir has been researched along with Sensitivity and Specificity in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, K; Chen, M; Deng, S; Jia, S; Jiang, W; Li, F; Shang, Y; Wang, F; Yang, S; Zhang, K | 1 |
| Cai, SH; Jiang, YG; Lv, FF; Peng, J; Zhang, YH | 1 |
| Bai, L; Chen, L; Feng, Y; Lu, W; Wang, W; Yuan, Z; Zhang, X; Zhang, Z; Zheng, Y | 1 |
| Chen, L; Ding, Y; Wang, D; Xiao, Q; Yang, J; Yang, W | 1 |
| Degertekin, B; Hussain, M; Lok, AS; Oberhelman, K; Tan, J | 1 |
| Barguès, G; Boyer, V; Germi, R; Hilleret, MN; Larrat, S; Leroy, V; Lupo, J; Morand, P; Nicod, S; Seigneurin, JM; Zarski, JP | 1 |
| Chen, LY; Gan, JH; Shao, YL; Wu, JH; Xiong, H; Zhao, WF; Zhu, YL | 1 |
| Choi, JJ; Jang, H; Kim, J; Park, H; Son, Y | 1 |
| Garcia, L; Lin, CC; Liu, Y; Xu, C; Xu, G; Yeh, LT | 1 |
| Dulai, GS; Farid, M; Gralnek, IM; Kanwal, F; Martin, P; Spiegel, BM | 1 |
| Bi, HC; Chen, X; Huang, M; Zhong, GP; Zhou, S | 1 |
| Andreone, P; Cursaro, C; Fung, S; Hussain, M; Libbrecht, E; Lok, AS; Sablon, E | 1 |
| Guo, R; Sun, D; Wang, B; Wang, H | 1 |
| Allice, T; Cerutti, F; Colucci, G; Franchello, A; Gabella, S; Ghisetti, V; Marzano, A; Pittaluga, F; Varetto, S | 1 |
| Aldern, KA; Beadle, JR; Hartline, CB; Hostetler, KY; Keith, KA; Kern, ER; Ruiz, JC | 1 |
| Balzarini, J; De Clercq, E; Hatse, S | 1 |
| Beijnen, JH; Hoetelmans, RM; Sparidans, RW; Veldkamp, A | 1 |
1 trial(s) available for adefovir and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of pradefovir, PMEA and tenofovir in HBV patient serum using liquid chromatography-tandem mass spectrometry and application to phase 2 clinical trial.
Topics: Adenine; Adult; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Linear Models; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Prodrugs; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tenofovir | 2016 |
17 other study(ies) available for adefovir and Sensitivity and Specificity
| Article | Year |
|---|---|
Rapid detection of hepatitis B virus variants associated with lamivudine and adefovir resistance by multiplex ligation-dependent probe amplification combined with real-time PCR.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Molecular Diagnostic Techniques; Multiplex Polymerase Chain Reaction; Mutation; Organophosphonates; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Time | 2014 |
Dynamic comparison between Daan real-time PCR and Cobas TaqMan for quantification of HBV DNA levels in patients with CHB.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Prospective Studies; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Viral Load; Young Adult | 2014 |
In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection.
Topics: Adenine; Case-Control Studies; DNA Probes; DNA, Viral; Hep G2 Cells; Hepatitis B Core Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; In Situ Hybridization; Liver; Organophosphonates; RNA, Viral; Sensitivity and Specificity; Virus Replication | 2016 |
Sensitivity and accuracy of an updated line probe assay (HBV DR v.3) in detecting mutations associated with hepatitis B antiviral resistance.
Topics: Adenine; Adult; Antiviral Agents; DNA Probes; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Sensitivity and Specificity | 2009 |
Assessment of selective real-time PCR for quantitation of lamivudine and adefovir hepatitis B virus-resistant strains and comparison with direct sequencing and line probe assays.
Topics: Adenine; Antiviral Agents; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Genotype; Hepatitis B virus; Humans; Lamivudine; Mutation; Organophosphonates; Plasmids; Polymerase Chain Reaction; Sensitivity and Specificity | 2009 |
Establishment of a new quantitative detection approach to adefovir-resistant HBV and its clinical application.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA; Young Adult | 2010 |
Peptide nucleic acid array for detection of point mutations in hepatitis B virus associated with antiviral resistance.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Microbial Sensitivity Tests; Mutation, Missense; Oligonucleotide Array Sequence Analysis; Organophosphonates; Peptide Nucleic Acids; Point Mutation; Sensitivity and Specificity | 2010 |
Ultra sensitive method for the determination of 9-(2-phosphonylmethoxyethyl)adenine in human serum by liquid chromatography-tandem mass spectrometry.
Topics: Adenine; Antiviral Agents; Chromatography, Liquid; Humans; Mass Spectrometry; Organophosphonates; Reproducibility of Results; Sensitivity and Specificity | 2004 |
Summaries for patients. Antiviral regimens for chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Decision Support Techniques; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver; Markov Chains; Organophosphonates; Recombinant Proteins; Salvage Therapy; Sensitivity and Specificity; Transaminases | 2005 |
Treatment alternatives for chronic hepatitis B virus infection: a cost-effectiveness analysis.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Decision Support Techniques; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver; Markov Chains; Organophosphonates; Recombinant Proteins; Salvage Therapy; Sensitivity and Specificity; Transaminases | 2005 |
Determination of adefovir in human plasma by liquid chromatography/tandem mass spectrometry: application to a pharmacokinetic study.
Topics: Adenine; Administration, Oral; Adult; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Male; Metabolic Clearance Rate; Organophosphonates; Pharmacokinetics; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir.
Topics: Adenine; Antiviral Agents; Base Sequence; DNA Probes; DNA, Viral; Drug Resistance, Viral; Genes, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; In Vitro Techniques; Lamivudine; Mutation; Organophosphonates; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Sensitivity and Specificity; Virology | 2006 |
Development and validation of a sensitive LC-MS/MS method for the determination of adefovir in human serum and urine.
Topics: Adenine; Adult; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Humans; Male; Mass Spectrometry; Organophosphonates; Sensitivity and Specificity | 2006 |
COBAS AmpliPrep-COBAS TaqMan hepatitis B virus (HBV) test: a novel automated real-time PCR assay for quantification of HBV DNA in plasma.
Topics: Adenine; Antiviral Agents; Automation; Biopsy; DNA, Viral; Drug Resistance, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Nucleic Acid Amplification Techniques; Organophosphonates; Polymerase Chain Reaction; Sensitivity and Specificity; Taq Polymerase; Viremia | 2007 |
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cowpox; Cytomegalovirus Infections; Cytosine; Herpes Simplex; HIV-1; Humans; In Vitro Techniques; Molecular Structure; Organophosphonates; Sensitivity and Specificity; Vaccinia | 2007 |
Enhanced 9-(2-phosphonylmethoxyethyl)adenine secretion by a specific, indomethacin-sensitive efflux pump in a mutant 9-(2-phosphonylmethoxyethyl)adenine-resistant human erythroleukemia K562 cell line.
Topics: Adenine; Adenine Nucleotides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cycloheximide; Dactinomycin; Drug Resistance, Neoplasm; Extracellular Space; Flow Cytometry; Humans; Immunoblotting; Indomethacin; K562 Cells; Mice; Multidrug Resistance-Associated Proteins; Mutation; Organophosphonates; Prodrugs; Protein Synthesis Inhibitors; Sensitivity and Specificity; Temperature; Zidovudine | 1998 |
Improved and simplified liquid chromatographic assay for adefovir, a novel antiviral drug, in human plasma using derivatization with chloroacetaldehyde.
Topics: Acetaldehyde; Adenine; Antiviral Agents; Chemical Precipitation; Chromatography, Liquid; Drug Stability; Fluorescent Dyes; Humans; Indicators and Reagents; Mass Spectrometry; Organophosphonates; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Trichloroacetic Acid | 1999 |