| Assay ID | Title | Year | Journal | Article |
|---|
| AID432608 | Binding affinity to 200 nM wild type HIV1 LAI reverse transcriptase assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex at 100 uM | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID619511 | Cytotoxicity against human CEM-T4 cells assessed as cell viability after 7 days by MTT assay | 2011 | Journal of medicinal chemistry, Oct-13, Volume: 54, Issue:19
| Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity. |
| AID341983 | Ratio of Kcat to Km for HIV1 reverse transcriptase assessed as nucleotide excision activity in presence of 0.5 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID74259 | In vitro inhibition of UDP-[3H]-GlcNAc import into the lumen of the Golgi membranes from rabbit liver homogenate. | 1996 | Journal of medicinal chemistry, Jul-19, Volume: 39, Issue:15
| Inhibition of UDP-N-acetylglucosamine import into Golgi membranes by nucleoside monophosphates. |
| AID221371 | Concentration of external nucleoside in mouse brain | 1992 | Journal of medicinal chemistry, Aug-07, Volume: 35, Issue:16
| Improved brain delivery of AZT using a glycosyl phosphotriester prodrug. |
| AID341976 | Inhibition of HIV1 reverse transcriptase assessed as dCTP level required to form 50% of binary enzyme complex formation with drug-terminated primer in posttranslocation state by site-specific foot printing assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID680358 | TP_TRANSPORTER: efflux in CEM-r1 cells | 1999 | Nature medicine, Sep, Volume: 5, Issue:9
| MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. |
| AID24894 | Half life evaluated in Culture Medium(CM) | 1995 | Journal of medicinal chemistry, Sep-29, Volume: 38, Issue:20
| Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate. |
| AID432590 | Binding affinity to wild type HIV1 LAI reverse transcriptase assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432613 | Selectivity ratio of Kd for excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex in 200 nM HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant to Kd for excision of zidovudine-monophosphate from chain terminated DNA | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID553326 | Ratio of kcat/km for human recombinant TMPK by Michaelis-Menten equation analysis | 2011 | Journal of medicinal chemistry, Jan-13, Volume: 54, Issue:1
| Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates. |
| AID235817 | ratio of Ki (Km TMPKh / Ki TMPKmt) was determined | 2003 | Journal of medicinal chemistry, Aug-28, Volume: 46, Issue:18
| 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. |
| AID432605 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated RNA/DNA template/primer duplex | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432607 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V/G333D mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated RNA/DNA template/primer duplex | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432609 | Binding affinity to 200 nM HIV1 LAI reverse transcriptase M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex at 100 uM | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432601 | Selectivity ratio of Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain in HIV1 LAI reverse transcriptase M41L/L210W/T215Y/K65R mutant to Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/prim | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID74253 | Inhibitory concentration at which there is accumulation of UDP-[3H]-GlcNAc in the lumen of the Golgi membranes. | 1996 | Journal of medicinal chemistry, Jul-19, Volume: 39, Issue:15
| Inhibition of UDP-N-acetylglucosamine import into Golgi membranes by nucleoside monophosphates. |
| AID341977 | Inhibition of HIV1 reverse transcriptase assessed as dCTP level required to form 80% of binary enzyme complex formation with drug-terminated primer in posttranslocation state by site-specific foot printing assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID325367 | Activity for human recombinant TMP kinase | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5
| Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs. |
| AID222817 | In Vitro detection by Gray and Whittaker method for the total internal nucleoside | 1992 | Journal of medicinal chemistry, Aug-07, Volume: 35, Issue:16
| Improved brain delivery of AZT using a glycosyl phosphotriester prodrug. |
| AID91571 | Inhibition of 3' processing step useful in the integration of viral DNA into host cell DNA by inhibiting HIV integrase by compound | 2000 | Bioorganic & medicinal chemistry letters, Feb-07, Volume: 10, Issue:3
| Recognition and inhibition of HIV integrase by a novel dinucleotide. |
| AID341980 | Activity of HIV1 reverse transcriptase assessed as nucleotide excision activity in presence of 10 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID341987 | Ratio of Kcat/Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant to Kcat/Km for wild-type reverse transcriptase assessed as nucleotide excision activity in presence of 0.5 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID325368 | Ratio of Kcat to Km of human recombinant TMPK relative to D4TDP | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5
| Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs. |
| AID341985 | Ratio of Kcat to Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant assessed as nucleotide excision activity in presence of 0.5 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID341978 | Binding affinity to ternary complex of HIV1 reverse transcriptase with primer/template in presence of dCTP substrate | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID432603 | Binding affinity to wild type HIV1 LAI reverse transcriptase assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated RNA/DNA template/primer duplex | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID221610 | In Vitro detection by Gray and Whittaker method for % of internalization by comparing with external nucleoside of 2000 nM/g | 1992 | Journal of medicinal chemistry, Aug-07, Volume: 35, Issue:16
| Improved brain delivery of AZT using a glycosyl phosphotriester prodrug. |
| AID432606 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated RNA/DNA template/primer duplex | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432612 | Binding affinity to 200 nM HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V/G333D mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex at 100 uM | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432593 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432599 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/K65R mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432591 | Binding affinity to HIV1 LAI reverse transcriptase M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432597 | Selectivity ratio of Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain in HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant to Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/pri | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID341991 | Inhibition of HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant assessed as dCTP level required to form 50% of binary enzyme complex formation with drug-terminated primer in posttranslocation state by site-specific foot printing assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID432596 | Selectivity ratio of Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain in HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant to Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer du | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID341979 | Activity of HIV1 reverse transcriptase assessed as nucleotide excision activity in presence of 0.5 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID619513 | Antiviral activity against HIV1 infected in human CEM-T4 cells assessed as reduction in viral protein p24 production preincubated for 24 hrs measured after 8 days by MTT assay | 2011 | Journal of medicinal chemistry, Oct-13, Volume: 54, Issue:19
| Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity. |
| AID341990 | Ratio of Kcat/Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant in presence of 0.5 uM dCTP to Kcat/Km for reverse transcriptase M41L/D67N/L210W/T215Y mutant in presence of 10 uM dCTP by nucleotide excision activity assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID24898 | Half life evaluated in Total Cell Extract(TCE). | 1995 | Journal of medicinal chemistry, Sep-29, Volume: 38, Issue:20
| Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate. |
| AID341984 | Ratio of Kcat to Km for HIV1 reverse transcriptase assessed as nucleotide excision activity in presence of 10 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID341981 | Activity of HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant assessed as nucleotide excision activity in presence of 0.5 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID341989 | Ratio of Kcat/Km for HIV1 reverse transcriptase in presence of 0.5 uM dCTP to Kcat/Km for reverse transcriptase in presence of 10 uM dCTP by nucleotide excision activity assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID210900 | In Vitro inhibition of Thymidine Monophosphatase Kinase (TMPKh) | 2003 | Journal of medicinal chemistry, Aug-28, Volume: 46, Issue:18
| 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. |
| AID432598 | Selectivity ratio of Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain in HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V/G333D mutant to Kd for excision of zidovudine-monophosphate terminated DNA/DNA templa | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID210897 | In Vitro inhibition of Thymidine Monophosphatase Kinase of Mycobacterium tuberculosis (TMPKm) | 2003 | Journal of medicinal chemistry, Aug-28, Volume: 46, Issue:18
| 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. |
| AID619510 | Chemical stability of the compound in RPMI cell culture media assessed as half life at 2 mM | 2011 | Journal of medicinal chemistry, Oct-13, Volume: 54, Issue:19
| Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity. |
| AID635863 | Competitive inhibition of Mycobacterium tuberculosis TMPK expressed in Escherichia coli NM554 by coupled spectrophotometric assay | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24
| Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase. |
| AID341992 | Inhibition of HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant assessed as dCTP level required to form 80% of binary enzyme complex formation with drug-terminated primer in posttranslocation state by site-specific foot printing assay | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID432610 | Binding affinity to 200 nM HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex at 100 uM | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID91572 | Inhibition of strand transfer step useful in the integration of viral DNA into host cell DNA by inhibiting HIV integrase by compound | 2000 | Bioorganic & medicinal chemistry letters, Feb-07, Volume: 10, Issue:3
| Recognition and inhibition of HIV integrase by a novel dinucleotide. |
| AID432602 | Selectivity ratio of Kd for excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex in HIV1 LAI reverse transcriptase M41L/L210W/T215Y/K65R/G333D mutant to Kd for excision of zidovudine-monophosphate from chain terminated | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID210904 | Inhibitory activity against thymidine monophosphate kinase (TMPK) in Mycobacterium tuberculosis | 2003 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 13, Issue:18
| Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. |
| AID211055 | Compound was tested for binding affinity against Mycobacterium tuberculosis thymidine monophosphate kinase | 2002 | Bioorganic & medicinal chemistry letters, Oct-07, Volume: 12, Issue:19
| Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. |
| AID432611 | Binding affinity to 200 nM HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex at 100 uM | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432594 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V/G333D mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID341982 | Activity of HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant assessed as nucleotide excision activity in presence of 10 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID432595 | Selectivity ratio of Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain in HIV1 LAI reverse transcriptase M184V mutant to Kd for excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID341986 | Ratio of Kcat to Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant assessed as nucleotide excision activity in presence of 10 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID432592 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID619514 | Selectivity index, ratio of CC50 for human CEM-T4 cells to EC50 for HIV1 infected human CEM-T4 cells | 2011 | Journal of medicinal chemistry, Oct-13, Volume: 54, Issue:19
| Aryl H-phosphonates 17: (N-aryl)phosphoramidates of pyrimidine nucleoside analogues and their synthesis, selected properties, and anti-HIV activity. |
| AID341988 | Ratio of Kcat/Km for HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant to Kcat/Km for wild-type reverse transcriptase assessed as nucleotide excision activity in presence of 10 uM dCTP | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8
| Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. |
| AID74256 | The compound was tested for extent of UDP-[3H]-GlcNAc accumulation into the lumen of the Golgi membranes. | 1996 | Journal of medicinal chemistry, Jul-19, Volume: 39, Issue:15
| Inhibition of UDP-N-acetylglucosamine import into Golgi membranes by nucleoside monophosphates. |
| AID432600 | Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/K65R/G333D mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA template/primer duplex chain at 100 uM by gel shift mobility assay | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432604 | Binding affinity to HIV1 LAI reverse transcriptase M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate from chain terminated RNA/DNA template/primer duplex at 100 uM | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| AID432614 | Selectivity ratio of Kd for excision of zidovudine-monophosphate from chain terminated DNA/DNA template/primer duplex in 200 nM HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant to Kd for excision of zidovudine-monophosphate from chain terminated DNA | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
| Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |