Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
Excerpt | Reference |
"Seizures are also accompanied by significant reductions in extracellular Ca2+ activity (aCa) to as low as 0." | ( Heinemann, U; Lux, HD, 1978) |
"Type II (tonic) seizures are invariably associated with profound transient bradycardia, recovery from which begins about the time the tonic seizure phase ends." | ( Beaver, RW; Brauer, RW; Fuquay, J, 1979) |
"The seizures are characterized by running, hopping, and vocalizing and are mixed with shorter-duration tonic episodes." | ( Doerr, JK; Konkol, RJ; Madden, JA, 1992) |
"Cocaine-induced seizures are common and appear to be due to the local anaesthetic actions of this compound." | ( Djenderedjian, AH; Giombetti, R; Mena, I; Miller, BL; Villanueva-Meyer, J, 1992) |
"Experimental seizures are followed by an especially rapid and massive induction of brain ornithine decarboxylase (ODC), an enzyme which catalyses the rate-limiting step in the synthesis of polyamines." | ( de Belleroche, JS; Herberg, LJ; Mintz, M; Rose, IC, 1992) |
"Spinal cord seizures are infrequently reported." | ( Cross, LL; Meythaler, JM; Tuel, SM, 1991) |
"Seizures are a recognized manifestation of neurosarcoidosis, but their clinical relevance is not well established." | ( Krumholz, A; Stern, BJ; Stern, EG, 1991) |
"Treating seizures is a major part of a neurologic practice." | ( Bernstein, AL, 1990) |
"Experimental seizures are more readily produced in infant than adult rats, possibly related to a developmental predominance of NMDA receptor-mediated effects." | ( Pasternak, JF; Trommer, BL, 1990) |
"Eclamptic seizures are clinically and electroencephalographically indistinguishable from generalized tonic-clonic seizures." | ( Fisher, RS; Hanley, DF; Kaplan, PW; Lesser, RP; Repke, JT, 1990) |
"Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases." | ( Deeg, MA; Rajamani, K, 1990) |
"Seizures are a less frequent, but important complication." | ( Kieburtz, K; Moxley, RT; Ricotta, JJ, 1990) |
"When partial seizures are identified they are attributed to preceding brain damage, head trauma or stroke." | ( Baulac, M; Laplane, D, 1990) |
"Convulsive seizures are a potential side effect of antidepressant drug treatment and can be produced by all classes of antidepressants." | ( Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI, 1988) |
"Pilocarpine seizures are characterized by a sequential development of behavioral patterns and electrographic activity." | ( Bortolotto, ZA; Cavalheiro, EA; Ikonomidou, C; Turski, L; Turski, WA, 1989) |
"L-allylglycine seizures are associated with generalized decreases in regional GABA levels, and increases in regional glutamine levels." | ( Chapman, AG, 1985) |
"Neocortical focal seizures are characterized by motor jerks in one limb (Jacksonian type), head turning (adversive attack), or localized sensory manifestations, and limbic or psychomotor attacks by brief impairment of consciousness and often by motor automatisms." | ( Hess, CW, 1988) |
"Febrile seizures are common in children." | ( Wright, SW, 1987) |
"The seizures are characterized by one or two wild running fits which terminate in a tonic dorsiflexion with open mouth, followed by a catatonic state." | ( Depaulis, A; Kiesmann, M; Marescaux, C; Micheletti, G; Vergnes, M; Warter, JM, 1987) |
"Bilateral seizures are obtained after about 15 stimulations of the amygdala in the rat." | ( LeGal La Salle, G; Papy, JJ; Rougier, I; Vion-Dury, J, 1986) |
"Febrile seizures are a common problem." | ( Ater, SB; Bettis, DB, 1985) |
"These seizures are characterized by tonic spasm in the extremities, often accompanied by painful dysesthesias, and are fleeting, usually lasting no more than two minutes." | ( Cherrick, AA; Ellenberg, M, 1986) |
"Seizures are an occasional manifestation of phenytoin toxicity, particularly when levels are high." | ( Masdeu, JC; Stilman, N, 1985) |
"Her seizures are now treated successfully with phenytoin." | ( Soman, M; Swenson, C, 1985) |
"L-Allylglycine seizures are associated with generalized decreases in GABA concentrations (-32 to -54%), increases in glutamine concentrations (+10 to +53%), and a decrease in cortical aspartate concentration (-14%)." | ( Chapman, AG; Meldrum, BS; Premachandra, M; Westerberg, E, 1984) |
"Seizures are a common occurrence in patients who are dependent on alcohol." | ( McMicken, D, 1984) |
"Penicillin induced seizures are not affected by furosemide." | ( Kariv, N; Noy, S; Rubinstein, E; Schtacher, G, 1984) |
"These seizures are indistinguishable in quality from those induced by pentylenetetrazol (PTZ), and pretreatment with low doses of caffeine potentiates PTZ-induced seizures." | ( Marangos, PJ; Martino, AM; Paul, SM; Skolnick, P, 1981) |
"Sound-induced seizures are suppressed by the i." | ( Croucher, MJ; Krogsgaard-Larsen, P; Meldrum, BS, 1983) |
"Febrile seizures are a common pediatric problem, yet there is a great deal of disagreement about the appropriate diagnostic evaluation of a child with this disorder." | ( Berliner, BC; Gerber, MA, 1981) |
"Kynurenine seizures are suggested to be related to the action of kynurenine on glycine receptors in the central nervous system." | ( Lapin, IP, 1981) |
"Catamenial seizures are defined as epileptic seizures occurring during distinct phases of the menstrual cycle (i." | ( Bauer, J; Elger, CE; Hocke, A, 1995) |
"Drug-induced seizures are a potentially serious adverse effect." | ( Chatel, DM; Dahdal, WY; Franson, KL; Grossberg, GT; Hay, DP; Kotegal, S; Mirza, WU; Neppe, V; Szwabo, PA, 1995) |
"Initially seizures are discrete, then undergo waxing-and-waning of convulsive/electroencephalographic severity." | ( Handforth, A; Treiman, DM, 1995) |
"Seizures are a recognized complication of human immunodeficiency virus (HIV)-type-1 infection." | ( Bodian, C; Maker, H; Van Paesschen, W, 1995) |
"Audiogenic seizures are evoked by acoustic stimulation in susceptible (S) but not in resistant (R) rats." | ( Antunes-Rodrigues, J; Garcia-Cairasco, N; Oliveira, JA; Reis, LC; Terra, VC, 1994) |
"Amygdala-kindled seizures are more potently inhibited by phenytoin than by magnesium sulfate." | ( Cotton, DB; Irtenkauf, SM; Mason, B; Standley, CA; Stewart, L, 1994) |
"Since limbic seizures are a more injurious stimulus, the KROX-20 expression profile was investigated in adult rats subjected to kainic acid induced limbic epilepsy at postictal intervals up to 48 h." | ( Bravo, R; Gass, P; Herdegen, T; Kiessling, M, 1994) |
"Seizures are a rare complication after myelography with the current nonionic contrast agents and have not been previously reported in the emergency medicine literature." | ( Olsen, J, 1994) |
"Such seizures are more likely in the elderly, in the presence of pre-existing neurological disease, and when theophylline is given with certain antibiotics and cimetidine." | ( FitzGerald, MX; Hutchinson, J; Hutchinson, M; O'Riordan, JI, 1994) |
"Seizures are uncommon, but serious, adverse effects of antidepressant drugs." | ( Jacobs, SC; Nelson, JC; Rosenstein, DL, 1993) |
"These seizures are characterized by running/bouncing clonus and tonic extensor convulsions." | ( Bettendorf, AF; Browning, RA; Burger, RL; Jobe, PC; Mishra, PK, 1994) |
"Most such seizures are related to acute abstinence from chronic, high doses of alcohol use." | ( Earnest, MP, 1993) |
"Epileptic seizures are thought to terminate largely as a result of the extracellular accumulation of the purinergic neuromodulator, adenosine, released by discharging neurons." | ( Engelbrecht, AH; Herberg, LJ; Kellaway, L; Lamm, MC; Mintz, M; Russell, VA; Taljaard, JJ, 1996) |
"Convulsive seizures are among the most common problems involving the central nervous system." | ( Kraus, D; Schmolke, M; Thomasius, R, 1997) |
"Pilocarpine-induced seizures are initiated via muscarinic receptors and further mediated via NMDA receptors." | ( Ebinger, G; Khan, GM; Manil, J; Michotte, Y; Smolders, I, 1997) |
"Seizures are common in patients infected with human immunodeficiency virus (HIV)." | ( Dasgupta, A; McLemore, JL, 1998) |
"The SNR effects on seizures are site-specific within the SNR and developmentally regulated." | ( Löscher, W; Moshé, SL; Velísková, J, 1998) |
"In rodents these seizures are readily triggered by sound (audiogenic seizures)." | ( Faingold, CL; N'Gouemo, P; Riaz, A, 1998) |
"Seizures are commonly encountered in patients who do not have epilepsy." | ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
"Because cocaine seizures are relatively uncommon, they should be diagnosed by exclusion and a neurological workup to rule out central nervous system (CNS) catastrophe should be made." | ( Blaho, K; Geraci, S; Logan, B; Winbery, S, 1998) |
"Partial seizures are usually due to a structural cerebrocortical lesion and may be simple or complex." | ( March, PA, 1998) |
"Whereas neonatal seizures are a predictor of adverse neurological outcome, there is controversy regarding whether seizures simply reflect an underlying brain injury or can cause damage." | ( Ben-Ari, Y; Chevassus-Au-Louis, N; Gairsa, JL; Holmes, GL, 1998) |
"New-onset seizures are infrequent in patients with HIV." | ( Barrio, JL; Domingo, P; Escartin, A; Fuster, M; Iranzo, A; Marti-Fàbregas, J; Pascual-Sedano, B; Sambeat, MA, 1999) |
"Seizures are common after severe cerebral ischemia." | ( Kim, DC; Todd, MM, 1999) |
"Epileptic seizures are associated with increases in hippocampal excitability, but the mechanisms that render the hippocampus hyperexcitable chronically (in epilepsy) or acutely (in status epilepticus) are poorly understood." | ( Basbaum, AI; Cao, Y; Liu, H; Mazarati, AM; Sankar, R; Wasterlain, CG, 1999) |
"Partial onset seizures are more frequent among hazardous drinkers than hitherto recognized." | ( Bovim, G; Bråthen, G; Brodtkorb, E; Helde, G; Sand, T, 1999) |
"Seizures are a frequent problem confronting EMS personnel." | ( Nicholl, JS, 1999) |
"Tonic and clonic seizures are abolished at 15 min (ED(50s) 0." | ( Chapman, AG; Meldrum, BS; Nanan, K; Yip, P, 1999) |
"Although seizures are very common in neonates and are often the harbinger of poor neurologic outcome, there is controversy regarding the degree of brain damage induced by seizures during early development." | ( Holmes, GL; Schmid, R; Stafstrom, CE; Tandon, P, 1999) |
"Nicotine-induced seizures are centrally mediated and involve the activation of alpha7 along with other nicotinic receptor subunits." | ( Damaj, MI; Dukat, M; Glassco, W; Martin, BR, 1999) |
"All patients' seizures are fully controlled on once-a-day low-dose phenobarbital with no side effects." | ( Lerman, P; Lerman-Sagie, T, 1999) |
"Seizures are a well known consequence of human cocaine abuse, and in rodent models, sensitivity to cocaine seizures has been shown to be strongly influenced by genotype." | ( Belknap, JK; Bergeson, SE; Crabbe, JC; Hain, HS, 2000) |
"Seizures is a major toxicity of theophylline." | ( Gupta, YK; Malhotra, J, 1998) |
"Seizures are also often associated with tics and compulsions, which likewise involve cortical-limbic hyperactivity." | ( Burton, FH; Campbell, KM; McGrath, MJ; Veldman, MB, 2000) |
"The threshold for seizures is lowered by tramadol." | ( Levine, BS; Pestaner, JP; Ripple, MG; Smialek, JE, 2000) |
"Epileptic seizures are often not the main problem in atypical rolandic epilepsies like CSWS or LKS and the amelioration of cognitive dysfunction by epileptic discharge is the prominent aim of an AED therapy." | ( Rating, D, 2000) |
"Although neonatal seizures are quite common, there is controversy regarding their consequences." | ( Cha, BH; Cilio, MR; Holmes, GL; Liu, X; McCabe, BK; Silveira, DC; Sogawa, Y, 2001) |
"Febrile seizures are the most common seizures in childhood and, like all seizures, can be frightening to witness." | ( Baumann, RJ, 2001) |
"Subtle seizures are mild paroxysmal alterations in motor or autonomic activity and are unique to the neonatal period." | ( Aggarwal, R; Deorari, AK; Paul, VK; Upadhyay, A, 2001) |
"Seizures are associated with pronounced changes in regional cerebral blood flow." | ( Borbély, K, 2001) |
"Seizures are commonly associated with hypoxic-ischemic encephalopathy." | ( Armstrong, DL; Battin, MR, 2001) |
"Epileptic seizures are followed by dynamic alterations in neurological function in the postictal period." | ( Baumgartner, C; Leutmezer, F, 2002) |
"Other childhood seizures are also responsive to ACTH." | ( Burnham, WM; Edwards, HE; Vimal, S, 2002) |
"Pilocarpine-induced seizures are mediated by the M(1) subtype of muscarinic acetylcholine receptor (mAChR), but little is known about the signaling mechanisms linking the receptor to seizures." | ( Berkeley, JL; Decker, MJ; Levey, AI, 2002) |
"Seizures are an uncommon but serious complication of hyponatremia which can lead to permanent brain damage and even death." | ( Tokeshi, J; Youn, KS, 2002) |
"Epileptic seizures are associated with neuronal hyperactivity." | ( Bikson, M; Fox, JE; Hahn, PJ; Jefferys, JG, 2003) |
"Such seizures are more common among adolescents." | ( Bailine, SH; Doft, M; Lui, G; Petrides, G, 2003) |
"The seizures are resistant to conventional anticonvulsants." | ( Akre, B; Lundby, R; Rasmussen, M, 2004) |
"Some electrographic seizures are generated intracortically." | ( Grenier, F; Steriade, M; Timofeev, I, 2004) |
"Generalized seizures are commonly thought to involve the entire brain homogeneously." | ( Blumenfeld, H; McNally, KA, 2004) |
"Seizures are reported to occur more frequently among children with diagnoses of autism and pervasive developmental disorder (PDD), and some reports indicate a frequency as high as 30%." | ( Castello, FV; Mehta, UC; Patel, I, 2004) |
"Hypocalcemic seizures are uncommon and underdiagnosed complications of long-term therapy with AEDs." | ( Al-Busairi, WA; Al-Bustan, MA; Al-Mulla, FA; Ali, FE, 2004) |
"Neonatal seizures are the most common manifestation of underlying cerebral dysfunction." | ( Armstrong, EA; Jaharus, C; Saucier, DM; Wirrell, EC; Yager, JY, 2004) |
"Seizures are both caused by and induce a complex set of neurobiological alterations and adaptations." | ( Post, RM, 2004) |
"Experimental seizures are often accompanied by the generation of free radicals that cause lipid peroxidation (LPO), which may subsequently cause neurodegeneration observed in certain types of human epilepsy." | ( Rajasekaran, K, 2005) |
"Dyskinesias and seizures are both medically refractory disorders for which cannabinoid-based treatments have shown early promise as primary or adjunctive therapy." | ( Adrian, R; Baratta, J; Giuffrida, A; Piomelli, D; Solbrig, MV, 2005) |
"Seizures are an important adverse effect of bupropion and care is needed when used in other conditions or with other medication that can lower the seizure threshold." | ( Ross, S; Williams, D, 2005) |
"Centrally mediated seizures are a common consequence of exposure to organophosphates (OP) despite conventional treatment with atropine and an oxime." | ( Chapman, S; Gilat, E; Kadar, T, 2006) |
"Seizures are a common complication of primary (PBT) and metastatic (MBT) brain tumors, affecting approximately 50% of all patients during the course of their illness." | ( Goldlust, SA; Newton, HB; Pearl, D, 2006) |
"Seizures are a common neurologic symptom of tuberous sclerosis complex." | ( Chuck, G; Collins, JJ; Franz, DN; Leonard, JM; Tudor, C, 2006) |
"Seizures are the most common clinical manifestation and may be exacerbated by phenobarbitone." | ( Appleton, DB; Bowling, FG; Burke, CJ; Coman, DJ; De Vivo, DC; McGill, JJ; O'Neil, CM; Pelekanos, JT; Sinclair, KG; Wallace, GB; Wang, D, 2006) |
"Most neonatal seizures are triggered by acute illness such as hypoxic-ischemic encephalopathy, stroke, or infection; rarely are they triggered by epilepsy per se." | ( Clancy, RR, 2006) |
"Early postoperative seizures are defined as those that appear within the first week after surgery and are a well-known and feared complication in patients with supratentorial brain tumors." | ( Bomprezzi, C; Formica, F; Iacoangeli, M; Mauro, AM; Morresi, S; Provinciali, L; Scerrati, M, 2007) |
"Neonatal seizures are most commonly incited by serious acute illnesses such as hypoxic-ischemic encephalopathy, birth trauma, or infection." | ( Clancy, RR, 2006) |
"Seizures are a common complication of metastatic brain tumors (MBT), affecting approximately 27-50% of all patients during the course of their illness." | ( Dalton, J; Goldlust, S; Newton, HB; Pearl, D, 2007) |
"Seizures are a rare complication during cerebral angiographic procedures." | ( Nwagwu, CI; Westhout, FD, 2007) |
"Kindled seizures are widely used to model epileptogenesis, but the molecular mechanisms underlying the attainment of kindling status are largely unknown." | ( Dunoiu, C; Ioana, M; Mogoantă, L; Petcu, EB; Pirici, D; Popa-Wagner, A, 2007) |
"Seizures are a common occurrence in the neonatal intensive care unit, especially among low-birth-weight infants." | ( Rotenberg, JS; Shoemaker, MT, 2007) |
"Sevoflurane-induced seizures are most often described during mask induction of anesthesia when high concentrations of the volatile agent are administered concomitant with alveolar hyperventilation." | ( Iqbal, Z; Kumar, V; Markan, S; Mohanram, A; Pagel, PS, 2007) |
"Seizures are a major complication of viral encephalitis." | ( Campbell, IL; Getts, DR; Getts, MT; King, NJ; Matsumoto, I; Müller, M; Radford, J; Shrestha, B, 2007) |
"A potential role in seizures is suggested by Newton et al." | ( Atassi, H; Croll, SD; Elkady, A; Goodman, JH; Hylton, D; McCloskey, DP; Nicoletti, JN; Rudge, JS; Scharfman, HE; Shah, SK, 2008) |
"Although seizures are very common during early brain development, consequences of seizures during this age period are less severe than in the mature brain." | ( Stafstrom, CE, 2007) |
"Prevention of seizures is needed when HBO is used as preconditioning method." | ( Li, J; Liu, K; Liu, W; Sun, X; Tao, H; Xu, W; Zhang, JH, 2008) |
"Early onset of seizures is linked to the combined MECP2 and BDNF genotypes." | ( Bahi-Buisson, N; Bienvenu, T; Chelly, J; Coste, J; De Roux, N; Guellec, I; Nectoux, J; Rosas, H; Tardieu, M, 2008) |
"Epileptiform seizures are most common during the neonatal period, affecting at least 0." | ( Bari, F; Domoki, F; Zimmermann, A, 2008) |
"Whereas propagated seizures are known to disrupt cerebral activity, little work has been done on remote network effects of seizures that do not propagate." | ( Blumenfeld, H; Englot, DJ; Herman, P; Hyder, F; Mansuripur, PK; Mishra, AM, 2008) |
"Seizures are a recognized complication of citalopram overdose." | ( Graham, A; Gray, JA; Waring, WS, 2008) |
"Generalized seizures are an important manifestation of citalopram toxicity, and cannot be explained solely by electrolyte disturbances or co-ingestion of other drugs or ethanol." | ( Graham, A; Gray, JA; Waring, WS, 2008) |
"Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures." | ( Barbaro, N; Burt, M; Chakalian, L; Chang, E; Chang, S; Lamborn, KR; Lim, DA; McDermott, MW; Tarapore, P, 2009) |
"Neonatal seizures are one of the most common neurological disorders in infants." | ( Blume, HK; Christakis, DA; Garrison, MM, 2009) |
"Epileptic seizures are a common clinical problem in children with brain tumors." | ( Attinà, G; Battaglia, D; Mastrangelo, S; Riccardi, R; Rizzo, D; Ruggiero, A, 2010) |
"Seizures are a recognized complication of acute overdose with the racemic (1:1 ratio of R- and S-enantiomers) selective serotonin reuptake inhibitor antidepressant citalopram." | ( Bauer, K; Ceschi, A; Gerber-Zupan, G; Hackl, E; Hoffmann-Walbeck, P; Kullak-Ublick, GA; Kupferschmidt, H; Prasa, D; Rauber-Lüthy, C; Sauer, O; Seidel, C; Stedtler, U; Wilks, M; Yilmaz, Z, 2010) |
"Seizures are a frequently reported adverse effect of bupropion in therapeutic oral doses; however, there are limited data about the consequences of nasal insufflation of bupropion." | ( Kim, D; Steinhart, B, 2010) |
"Neonatal seizures are associated with a high likelihood of adverse neurological outcomes, including mental retardation, behavioral disorders, and epilepsy." | ( Holmes, GL; Isaev, D; Isaeva, E; Khazipov, R; Savrasova, A, 2010) |
"Seizures are a common phenotype in all of these neurological disorders, yet the underlying molecular mechanism(s) of seizure induction and propagation remain largely unknown." | ( Malter, JS; Westmark, CJ; Westmark, PR, 2010) |
"EEG seizures are associated with prolonged deep hypothermic circulatory arrest and with adverse long-term neurodevelopmental outcomes." | ( Andropoulos, DB; Dickerson, HA; Fraser, CD; Heinle, JS; Hrachovy, RA; McKenzie, ED; Meador, MR; Mizrahi, EM; Stark, AR; Stayer, SA, 2010) |
"EEG seizures are infrequent in neonates undergoing surgery with high-flow CPB." | ( Andropoulos, DB; Dickerson, HA; Fraser, CD; Heinle, JS; Hrachovy, RA; McKenzie, ED; Meador, MR; Mizrahi, EM; Stark, AR; Stayer, SA, 2010) |
"Subtle seizures are the commonest type of seizures occurring in the neonatal period." | ( Agarwal, R; Deorari, A; Paul, VK; Sankar, JM, 2010) |
"Seizures are a common sequela of self-poisoning." | ( Eddleston, M; Shah, AS, 2010) |
"Seizures are reported as an uncommon side effect of interferon therapy." | ( Ahmed, F; Albert, C; Brand, M; Brass, C; Brown, R; Fixelle, AM; Herrera, JL; Jacobson, IM; Rustgi, VK; Wasserman, RB, 2011) |
"Neonatal seizures are common, especially in prematurity." | ( Dinger, J; Ikonomidou, C; Ramantani, G; Rating, D; Walter, B, 2011) |
"Eating-induced seizures are an uncommon presentation of reflex epilepsy, a condition characterized by seizures provoked by specific stimuli." | ( Friedman, DE; Kung, DH; Manyam, SC; Newmark, ME; Rhodes, LB, 2010) |
"Considering that seizures are precipitated by common infections in children with GA-I, we investigated whether lipopolysaccharide (LPS) modifies GA-induced electrographic and neurochemical alterations in 21 days-old rats." | ( Ferreira, J; Fighera, MR; Furian, AF; Magni, DV; Mello, CF; Oliveira, AP; Oliveira, MS; Royes, LF; Santos, AR; Souza, MA, 2011) |
"Neonatal seizures are often refractory to treatment with initial antiseizure medications." | ( Abend, NS; Clancy, RR; Dlugos, DJ; Gutierrez-Colina, AM; Monk, HM, 2011) |
"Both types of seizures are suppressed by VB(6)." | ( Ohtahara, S; Ohtsuka, Y; Yamatogi, Y, 2011) |
"Acute seizures are readily recognizable episodes requiring urgent treatment." | ( Chen, YI; Chiang, LM; Chou, ML; Deng, ST; Hung, PC; Lin, KL; Shen, HH; Tseng, CH; Wang, HS, 2011) |
"Seizures are induced in some patients even at low doses." | ( Beasley, DM; Gee, P; Schep, LJ; Slaughter, RJ; Vale, JA, 2011) |
"While early-life seizures are considered a major cause for cognitive impairment, it is not known whether it is the seizures, the underlying neurological substrate or a combination that has the largest impact on eventual learning and memory." | ( Holmes, GL; Lenck-Santini, PP; Lucas, MM; Scott, RC, 2011) |
"The incidence of seizures is particularly high in the early ages of life." | ( Briggs, SW; Galanopoulou, AS, 2011) |
"Seizures are a common symptom of brain tumours." | ( Grant, R; Kerrigan, S, 2011) |
"These seizures are seldom reported in children in the literature and could be misinterpreted as generalized tonicoclonic seizures." | ( Dubois-Teklali, F; Spitz, MA; Vercueil, L, 2012) |
"Seizures are common in critically ill patients and can impact morbidity and mortality." | ( Cherry, S; Elzawahry, H; Judd, L; LaRoche, S; Muniz, JC, 2012) |
"The incidence of seizures is generally accepted to be greater in patients with multiple sclerosis (MS) than in the general population, and rarely, MS can initially present as seizure." | ( Kendrick-Adey, AC; Sponsler, JL, 2011) |
"Seizures are a common complication in patients with central nervous system (CNS) tumors." | ( O'Reilly, M; Twomey, M; Wallace, EM, 2012) |
"Conversely, seizures are sensitive to changes in sex hormone levels, which in turn may affect the seizure-induced neuronal damage." | ( Desantis, KA; Velíšková, J, 2013) |
"Seizures are markedly drug resistant and few reports have suggested the efficacy of some antiepileptic drugs." | ( Auvin, S; Bellavoine, V; Delanoë, C; Mahfoufi, N; Merdariu, D, 2013) |
"Neonatal seizures are common and often reflect a severe underlying neurologic dysfunction in neonates." | ( Huang, LT; Lai, MC; Tain, YL; Yang, SN, 2012) |
"Drug-induced seizures are in view of a constantly ageing population and increasingly frequent polypharmacotherapy an increasing problem in daily routine praxis." | ( Block, F; Dafotakis, M, 2013) |
"Seizures are the manifestation of highly synchronized burst firing of a large population of cortical neurons." | ( Abramowitz, J; Birnbaumer, L; Flockerzi, V; Freichel, M; Gottschall, PE; Howell, MD; Phelan, KD; Rhee, SW; Shwe, UT; Wu, H; Zheng, F, 2013) |
"Seizures are a potentially devastating complication of resection of brain tumors." | ( Forman, A; Graham, S; Heimberger, AB; Hess, K; Lang, FF; McCutcheon, IE; Prabhu, SS; Qiao, W; Sawaya, R; Suki, D; Trinh, VT; Wang, X; Weinberg, JS; Wu, AS, 2013) |
"When (sub)clinical seizures are treated, there is no consensus about the most appropriate treatment for neonatal seizures and how to assess the efficacy of treatment." | ( de Vries, LS; Hellström-Westas, L; van Rooij, LG, 2013) |
"While seizures are usually intractable to medication in tuberous sclerosis complex (TSC), a common genetic cause of epilepsy, vigabatrin appears to have unique efficacy for epilepsy in TSC." | ( McDaniel, SS; Rensing, NR; Wong, M; Zhang, B, 2013) |
"Neonatal seizures are a naturally occurring source of neuronal overactivation and can lead to long-term epilepsy and cognitive deficits." | ( Jensen, FE; Klein, PM; Kosaras, B; Sun, H, 2013) |
"On the one hand, seizures are associated with excessive neuronal activity that can spread across the brain, suggesting run-away excitation." | ( Grasse, DW; Karunakaran, S; Moxon, KA, 2013) |
"Its effect on seizures is complex." | ( Bråthen, G; Brodtkorb, E; Helde, G; Reimers, A; Samsonsen, C, 2013) |
"Tardive seizures are typically associated with electroencephalographic evidence of ictal activity and motor manifestations of the tonic-clonic activity." | ( Karim, Y; McCormick, LM; Thisayakorn, P; Yamada, T, 2014) |
"Neonatal seizures are common in the first month of life and may impair neurodevelopmental outcome." | ( Cipriani, C; Crisp, E; Khan, O; Kirmani, B; Wright, C, 2013) |
"Neonatal seizures are a potentially life-threatening pediatric problem with a variety of causes, such as birth trauma, asphyxia, congenital anomalies, metabolic disturbances, infections, and drug withdrawal or intoxication." | ( Chen, L; Langhan, ML; Thornton, MD, 2013) |
"Although seizures are known to be harmful, recent evidence indicates that they can also lead to adaptations that protect neurons from further insult." | ( Friedman, L; Hu, S, 2014) |
"Neonatal seizures are often refractory to treatment with initial antiseizure medications." | ( Ariguloglu, EA; Koklu, E; Koklu, S, 2014) |
"Seizures are rare but well known side-effects of carbapenems, especially imipenem." | ( Beovic, B; Maticic, M; Soštaric, N, 2014) |
"Epileptic seizures are well-known neurological complications following stroke, occurring in 3% of patients." | ( Chen, JG; Guan, XL; He, JG; Hu, ZL; Luo, Y; Wang, F; Wu, PF; Xiao, W; Zhang, JT; Zhou, J, 2014) |
"Seizures are currently defined by their electrographic features." | ( Bennet, KE; Blaha, CD; Bower, MR; Chang, SY; Goerss, SJ; Kim, I; Lee, KH; Marsh, WR; Meyer, FB; Stead, M; Van Gompel, JJ; Worrell, GA, 2014) |
"Convulsive seizures are a serious postoperative complication after cardiac surgery." | ( Carroll, J; Djaiani, G; Garrido-Olivares, L; Jerath, A; Katznelson, R; Rao, V; Sharma, V; Wasowicz, M, 2014) |
"Seizures are a common manifestation of acute neurologic insults in neonates and are often resistant to the standard antiepileptic drugs that are efficacious in children and adults." | ( Kahle, KT; Kaila, K; Puskarjov, M; Ruusuvuori, E, 2014) |
"Seizures are the primary clinical manifestation which could be acute (secondary to active lesions) or remote symptomatic (due to calcified lesions)." | ( Chakrabarty, B; Gulati, S; Gupta, AK; Jain, P; Kumar, A; Pandey, RM; Sachan, D, 2014) |
"Flurothyl induced seizures are clinically as effective without the memory effects associated with electricity." | ( Cooper, K; Fink, M, 2014) |
"Seizures are a frequent complication of brain injury, including intracerebral hemorrhage (ICH), where seizures occur in about a third of patients." | ( Colbourne, F; Dickson, CT; Klahr, AC, 2015) |
"Seizures are a common symptom in patients with low-grade glioma (LGG), negatively influencing quality of life, if uncontrolled." | ( Dirven, L; Heimans, JJ; Koekkoek, JA; Postma, TJ; Reijneveld, JC; Taphoorn, MJ; Vos, MJ, 2015) |
"Clinical seizures are common intraoperative and postoperative complications of supratentorial craniotomies with intraoperative brain mapping." | ( Bello, L; Carrabba, G; Colombo, A; Conte, V; L'Acqua, C; Magni, L; Magnoni, S; Stocchetti, N, 2015) |
"Kainate-induced seizures are accompanied by leukotriene formation, and are reduced by inhibitors of LOX/COX pathway." | ( Arroyo, DS; Iribarren, P; Jesse, AC; Lenz, QF; Marafiga, JR; Masson, CJ; Mello, CF; Poersch, AB; Reschke, CR; Temp, FR, 2014) |
"Seizures are a common cause of neurologic disease, and phenobarbital (PB) is the most commonly used antiepileptic drug." | ( Barnes Heller, HL; Delamaide Gasper, JA; Robertson, M; Trepanier, LA, 2015) |
"Anxiety and seizures are closely similar neurobehavioral disorders and are regulated by limbic system." | ( Gulati, K; Ray, A, 2014) |
"Seizures are common but are self-limited." | ( Albertson, TE; Ford, JB; Lewis, JC; Owen, KP; Sutter, ME, 2014) |
"Seizures are a known adverse effect of clozapine therapy." | ( Park, SH; Williams, AM, 2015) |
"Seizures are a known co-occurring symptom of Alzheimer's disease, and they can accelerate cognitive and neuropathological dysfunction." | ( Harrison, FE; Kang, JQ; Kennard, JA; Warner, TA, 2015) |
"Seizures are accompanied by cardiovascular changes that are a major cause of sudden unexpected death in epilepsy (SUDEP)." | ( Bhandare, AM; Farnham, MM; Mohammed, S; Pilowsky, PM, 2015) |
"SSRI-induced seizures are rare and are more likely to be associated with larger doses and severe symptoms such as those present in serotonin syndrome." | ( McKean, J; Mokszycki, R; Watts, H, 2015) |
"Postoperative seizures are more common in the first month after cranial surgery." | ( Boza, FM; Gumà I Padró, J; Peralta Muñoz, S; Taberner Bonastre, MT, 2015) |
"In epilepsy, seizures are generated by abnormal synchronous activity in neurons." | ( Alberto, MV; Anne, S; Laura, MC; Xóchitl, FP, 2015) |
"Seizures are common during the neonatal period, often due to hypoxic-ischemic encephalopathy and may contribute to acute brain injury and the subsequent development of cognitive deficits and childhood epilepsy." | ( Boylan, GB; Dunleavy, M; Henshall, DC; Jimenez-Mateos, EM; Rodriguez-Alvarez, N; Waddington, JL, 2015) |
"In newborns, seizures are most commonly associated with hypoxic-ischemic encephalopathy (HIE)." | ( Raol, YH; Sampath, D; Shmueli, D; White, AM, 2015) |
"Neonatal seizures are commonly associated with hypoxic-ischemic encephalopathy." | ( Johnston, MV; Kadam, SD; Kang, SK, 2015) |
"Febrile seizures are the most common type of convulsive events in children." | ( Blumberg, MS; Kaila, K; Pospelov, AS; Puskarjov, M; Yukin, AY, 2016) |
"Epileptic seizures are generally unpredictable and arise spontaneously." | ( Beniczky, S; Caciagli, L; Koepp, MJ; Lehnertz, K; Pressler, RM, 2016) |
"Myoclonic seizures are a hallmark of feline audiogenic seizures (FARS)." | ( Bessant, C; Garosi, L; Harvey, RJ; Lowrie, M; Sparkes, A; Thomson, S, 2017) |
"Neonatal seizures are associated with long term disabilities including epilepsy and cognitive deficits." | ( Benke, TA; Bernard, PB; Castano, AM; O'Leary, H, 2016) |
"Generally, seizures are accompanied by changes in brain function leading to uncontrolled nerve activity causing high blood pressure, rapid heart rate, and abnormal heart rhythm." | ( Bhandare, AM; Farnham, MM; Kapoor, K; Pilowsky, PM, 2016) |
"Seizures are accompanied by an exacerbated activation of cerebral ion channels." | ( Aldana, BI; Reed, RC; Sitges, M, 2016) |
"Seizures are common following perinatal asphyxia and may exacerbate secondary neuronal injury." | ( Berg, M; Soll, R; Young, L, 2016) |
"Seizures are common complications for patients with brain tumors." | ( Nasr, ZG; Paravattil, B; Wilby, KJ, 2016) |
"Post-stroke seizures are considered as a major cause of epilepsy in adults." | ( Lei, Z; Liang, Y; Xu, ZC; Zhang, H, 2016) |
"Epileptic seizures are network-level phenomena." | ( Casteels, C; Cleeren, E; Goffin, K; Janssen, P; Premereur, E; Van Paesschen, W, 2016) |
"Seizures are bursts of excessive synchronized neuronal activity, suggesting that mechanisms controlling brain excitability are compromised." | ( Bassell, GJ; Danielson, SW; Danzer, SC; Engel, T; Gross, C; Henshall, DC; Jimenez-Mateos, EM; Pun, RYK; Rowley, S; Schroeder, LM; Thomas, KT; Tiwari, D; Xing, L; Yao, X, 2016) |
"Convulsive seizures are due to abnormal synchronous and repetitive neuronal discharges in the central nervous system (CNS)." | ( Asadi, S; Fereidoni, M; Kordi Jaz, E; Moghimi, A; Roohbakhsh, A; Shamsizadeh, A, 2017) |
"Neonatal seizures are a common problem in the neonatal intensive care unit and are frequently treated with antiepileptic drugs." | ( Ahmad, KA; Ahmad, SF; Bennett, MM; Clark, RH; Desai, SJ; Ng, YT; Tolia, VN, 2017) |
"These seizures are caused by sudden which may vary from a brief lapse of attention or muscle jerks, to severe and prolonged convulsions." | ( Jain, N; Jaiswal, J; Pathak, A; Singour, PK, 2018) |
"Seizures are more common in patients with early onset or progressive forms of the disease and prognosticate rapid progression to disability and death." | ( Binder, DK; Hasselmann, JPC; Khalaj, AJ; Lapato, AS; Szu, JI; Tiwari-Woodruff, SK, 2017) |
"Seizures are very common in children." | ( Julliand, S; Moretti, R; Rinaldi, VE; Titomanlio, L, 2019) |
"In conclusion, seizures are generally the most common complication by a spectrum of seizure types, and sometimes cause symptomatic epilepsy." | ( Arslan, M; Güngör, S; Kılıç, B; Selimoğlu, MA; Yılmaz, S, 2017) |
"Posttraumatic seizures are a medical problem affecting patients with traumatic brain injury." | ( Cao, Y; Liao, Z; Lu, XM; Mountney, A; Shear, DA; Tortella, FC, 2017) |
"Seizures are epileptic manifestations that are intrinsically modulated through different neurotransmitters and receptor systems." | ( Arzhang, A; Elahdadi Salmani, M; Goudarzi, I; Lashkarbolouki, T, 2017) |
"Seizures are a common early presentation in infants with tuberous sclerosis complex (TSC) and can be preceded by electrographic changes on electroencephalography (EEG) before clinical seizure onset." | ( Jan, S; McCoy, B; Whitney, R; Zak, M, 2017) |
"LGS type of seizures is epilepsy which is due to abnormal vibrations occurring in seizures." | ( Natchimuthu, V; Ramalingam, M; Ravi, S; Thomas, S, 2017) |
"Neonatal seizures are the most common clinical manifestation of Central Nervous System (CNS) dysfunction and are associated with various neurological sequelae." | ( Agrawal, A; Banergee, A, 2017) |
"Seizures are the commonest manifestation of brain parenchymal cysticercosis." | ( Sharma, R; Singh, G, 2017) |
"Seizures are typically not responsive to conventional antiepileptic drugs, but they cease after parental pyridoxine administration." | ( Corsello, G; Falsaperla, R, 2017) |
"Epileptic seizures are rare in nonalcoholic WE." | ( Chen, H; Chen, X; Hong, H; Li, X; Shang, W; Tang, S, 2017) |
"Seizures are rare manifestation of thalamic disorder." | ( Brohi, H; Kumar, R; Mughul, A, 2017) |
"Seizures are common in infants with HIE undergoing TH and may worsen outcome." | ( Aronowitz, E; Hutton, A; Krishna, S; Moore, H; Vannucci, SJ, 2018) |
"Epileptic seizures are short episodes of abnormal brain electrical activity." | ( Choi, BY; Choi, HC; Hong, DK; Jeong, JH; Kho, AR; Lee, SH; Lee, SY; Song, HK; Suh, SW, 2017) |
"Seizures are the most common neurological complication in neonatal intensive care units." | ( Lancaster, S; Manganas, LN; McHugh, DC, 2018) |
"Epileptic seizures are refractory to treatment in approximately one-third of patients despite the recent introduction of many newer antiepileptic drugs (AEDs)." | ( Dash, A; Desudchit, T; Leung, H; Lim, KS; Tiamkao, S; Tsai, JJ; Wu, T, 2018) |
"Neonatal seizures are treated with phenobarbital and prolonged treatment does not prevent postneonatal epilepsy." | ( Beatty, CW; Gust, J; Hamiwka, L; Natarajan, N, 2018) |
"Seizures are important complications following a subarachnoid hemorrhage (SAH)." | ( Buxton, J; Mahmoud, SH, 2017) |
"An early onset of seizures is common in MLC." | ( Boschert, U; Brouwers, E; Bugiani, M; Dubey, M; Hamilton, EMC; Koch, H; Kole, MHP; Mansvelder, HD; Min, R; Stiedl, O; van der Knaap, MS; Wykes, RC, 2018) |
"Seizures are present in over 90% of infants and children with Wolf-Hirschhorn syndrome (WHS)." | ( Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C, 2018) |
"Catamenial seizures are believed to be a neurosteroid withdrawal symptom, and it was hypothesized that exogenous administration of progesterone to maintain its levels high during luteal phase will treat catamenial seizures." | ( Joshi, S; Kapur, J, 2019) |
"Seizures are common in newborns after asphyxia at birth and are often refractory to anti-seizure agents." | ( Bennet, L; Davidson, JO; Draghi, V; Galinsky, R; Gunn, AJ; Lear, CA; Unsworth, CP, 2018) |
"Seizures are controllable with antiepileptic drugs (AEDs) in about 70% of epilepsy patients, however, there remains about 30% of patients inadequately medicated with these AEDs, who need a satisfactory control of their seizure attacks." | ( Kondrat-Wróbel, MW; Łuszczki, JJ, 2018) |
"Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory cortex." | ( Hensch, TK; Jensen, FE; Lippman-Bell, JJ; Sun, H; Takesian, AE; Wang, TT, 2018) |
"Persistent seizures are associated with physical injury, reduced quality of life, and psychosocial impairment." | ( De Rosendo, J; Howard, D; Patel, V; Tremblay, G; Tsong, W, 2018) |
"Neonatal seizures are harmful to the developing brain and are associated with mortality and long-term neurological comorbidities." | ( Carter, BM; Kadam, SD; Kharod, SC, 2018) |
"Neonatal seizures are frequent in neonatal intensive care and the most common cause is perinatal asphyxia." | ( Cools, F; Demeulemeester, V; Lefevere, J; Van Hautem, H, 2018) |
"Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal astrocyte-neuron interplay remains elusive." | ( Åbjørsbråten, KS; Enger, R; Heuser, K; Jensen, V; Nagelhus, EA; Nome, CG; Pettersen, KH; Sprengel, R; Tang, W; Taubøll, E, 2018) |
"Seizures are sustained neuronal hyperexcitability in brain that result in loss of consciousness and injury." | ( Han, L; He, Q; Ji, X; Jin, M; Liu, K; Sheng, W, 2018) |
"Seizures are common in term infants with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia." | ( Chanlaw, T; Cho, A; Garg, M; Hussain, SA; Rao, LM; Sankar, R; Zaki, T, 2018) |
"Seizures are easily controlled by AEDs." | ( Kalita, J; Kumar, V; Misra, UK; Parashar, V, 2019) |
"Seizures are commonly thought to occur in a spontaneous, unpredictable manner." | ( Hassan, I; Hrazdil, CT; Randhawa, J, 2019) |
"Seizures are a feature not only of the many forms of epilepsy, but also of global metabolic diseases such as mitochondrial encephalomyopathy (ME) and glycolytic enzymopathy (GE)." | ( Barile, ZJ; Fogle, KJ; Gutierrez, AC; Hertzler, JI; McCardell, CS; Novak, MO; Palladino, MJ; Satterfield, SL; Shon, JH; Smith, AR, 2019) |
"Epileptic seizures are frequent in patients with glioblastoma, and anticonvulsive treatment is often necessary." | ( Bergner, C; Hörnschemeyer, J; Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Linnebacher, M; Mullins, CS; Porath, K; Weßlau, K, 2019) |
"Neonatal seizures are different from adult seizures, and many antiepileptic drugs that are effective in adults often fail to treat neonates." | ( Bai, Y; Chen, G; Dong, F; Feng, M; Huo, Q; Li, ST; Long, C; Lüscher, B; Ren, L; Wang, GL; Wang, Y; Wu, G; Wu, Z, 2019) |
"However, seizures are not typical and the majority of them were seizure-free." | ( Goji, A; Imoto, I; Ito, H; Kagami, S; Kohmoto, T; Mori, K; Mori, T; Toda, Y, 2019) |
"The prevalence of seizures is reported to be 1." | ( Basha, MM; Bernitsas, E; Marawar, R; Sriwastava, S; Yarraguntla, K; Zutshi, D, 2019) |
"Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression." | ( Abdel Baki, SG; Birbeck, GL; Capparelli, EV; Dzinjalamala, FK; Gardiner, JC; Herman, ST; Mallewa, M; Postels, DG; Seydel, KB; Taylor, TE; Toto, NM, 2019) |
"Unlike in children, seizures are unusual in adult patients with eucalyptus oil poisoning." | ( George, GR; Ittyachen, AM; Joy, Y; Radhakrishnan, M, 2019) |
"Seizures are uncommon among younger children with exploratory ingestions." | ( Gosen, J; Levine, M; Offerman, S; Thomas, SH, 2020) |
"Epileptic seizures are frequent in patients with glioma, and anticonvulsive treatment is often indicated." | ( Kirschstein, T; Köhling, R; Krause, BJ; Lange, F; Mayer, J; Porath, K; Resch, T, 2020) |
"Seizures are induced when subjects are exposed to severe hypoxia." | ( Fukushi, I; Horiuchi, J; Kurita, Y; Mori, Y; Okada, Y; Okazaki, S; Pokorski, M; Takeda, K; Uchiyama, M; Yokota, S, 2020) |
"Drug-resistant seizures are life-threatening and contribute to sustained hospitalization." | ( Capra, S; Narayan, SW; Parratt, K; Patanwala, AE, 2020) |
"Controlling seizures is essential during GBM treatment because they are often present and closely associated with the quality of life of GBM patients." | ( Chang, MJ; Min, KL; Ryu, JY, 2019) |
"Epileptic seizures are characterized by synchronized discharges of neurons, leading to the activation of inflammatory responses that in turn contributes to seizure progression." | ( Ji, X; Jin, M; Liu, K; Sik, A; Wang, L; Zhang, B; Zhang, S, 2020) |
"Neonatal seizures are difficult to diagnose and, when they are, tradition dictates first line treatment is phenobarbital." | ( Alix, JJP; Gossling, L; Hart, AR; Stavroulakis, T, 2020) |
"Seizures are a combination of electrical and behavioral events that can induce biochemical, molecular, and anatomic changes." | ( Adem, A; Alachkar, A; Frank, A; Ojha, SK; Sadek, B; Sadeq, A; Stark, H, 2020) |
"Seizures are a morbid complication of intracerebral hemorrhage (ICH) and increase the risk for herniation, status epilepticus, and worse patient outcomes." | ( Naidech, AM; Pinto, D; Prabhakaran, S; Tipton, E, 2020) |
"Seizures are known to trigger a neuroinflammatory response to promote neuronal damage and increase the risk of epilepsy." | ( Fox, P; Koh, S; Mithal, DS; Sanchez, RM; Somogyi, JR; Vien, AC, 2020) |
"As seizures are precipitated in children with GA-I and the mechanisms underlying this disorder are not well established, we decided to investigate the role of nitric oxide (NO) in GA-induced convulsive behaviour in pup rats." | ( Bortolatto, CF; Brüning, CA; Magni, DV; Nogueira, CW; Nonemacher, NT; Quines, CB; Rosa, SG, 2020) |
"Acute symptomatic seizures are possible in patients with COVID-19 disease." | ( Bhimraj, A; George, P; Hantus, S; Hepburn, M; Mullaguri, N; Newey, CR; Punia, V, 2021) |
"As seizures are commonly associated with autonomic manifestations, we believe that biomarkers for diseases affecting autonomic functions such as epilepsy can be found in vagus nerve signals." | ( Cury, J; Delbeke, J; Doguet, P; Hermans, E; Nielsen, TN; Nonclercq, A; Sevcencu, C; Smets, H; Stumpp, L; Tahry, RE; Vespa, S, 2020) |
"Seizures are frequently pharmacoresistant." | ( Samanta, D, 2021) |
"Neonatal seizures are frequently encountered in the neonatal intensive care unit and may be associated with serious long-term neurological sequelae." | ( Darwich, M; Hanneyan, S; Hnaini, M; Jaafar, F; Koleilat, N; Maalouf, FI; Mikati, IE; Nabout, R; Obeid, M; Rahal, S; Shbarou, RM, 2020) |
"Neonatal seizures are one of the most common comorbidities of neonatal encephalopathy, with seizures aggravating acute injury and clinical outcomes." | ( Engel, T; Menéndez Méndez, A; Smith, J, 2020) |
"First unprovoked seizures are not influenced by the lunar cycle." | ( Boston, R; Lawn, N; Seneviratne, U; Wang, S, 2022) |
"Epileptic seizures are automatic, excessive, and synchronized neuronal activities originating from many brain regions especially the amygdala, the allocortices and neocortices." | ( Chou, P; Hsueh, SW; Kuo, CC; Wang, GH; Yang, YC, 2021) |
"Neonatal seizures are the most frequent type of neurological emergency in newborn infants, often being a consequence of prolonged perinatal asphyxia." | ( Ala-Kurikka, T; Gailus, B; Hampel, P; Johne, M; Kaila, K; Löscher, W; Römermann, K; Theilmann, W, 2021) |
"Seizures are a threat to the host brain and body and can even cause death in epileptic children." | ( Eor, JY; Kim, SH; Kwak, MJ; Son, YJ; Tan, PL, 2021) |
"Epileptic seizures are considered to be a brain network dysfunction, and chronic recurrent seizures can cause severe brain damage." | ( Chen, C; Li, F; Liang, Y; Xu, P; Yao, D; Yu, L, 2020) |
"Epileptic seizures are characterized by imbalanced inhibition-excitation cycle that triggers biochemical alterations responsible for jeopardized neuronal integrity." | ( Mishra, P; Rajput, SK; Sinha, JK, 2021) |
"Since seizures are highly unlikely to be detected in a routine scalp EEG, the primary diagnosis depends heavily on the visual evaluation of Interictal Epileptiform Discharges (IEDs)." | ( Cash, SS; Chaudhari, R; Dauwels, J; Jing, J; Karia, S; Peh, WY; Rathakrishnan, R; Saini, V; Shah, N; Srivastava, R; Tan, YL; Thangavel, P; Thomas, J; Westover, B; Yuvaraj, R, 2021) |
"Sevoflurane-induced seizures are most often caused by high concentrations of sevoflurane during anesthesia induction." | ( Du, L; Zhang, L; Zheng, J, 2021) |
"Epileptic seizures are the most common neurological diseases that change the function of neurovascular unit at molecular levels accompanied by activation of a wide variety of neurodegenerative cascades." | ( Darabi, S; Faghihi, N; Mohammadi, MT; Sarahian, N, 2021) |
"Seizures are a common manifestation of toxic exposures requiring immediate and possibly ongoing management." | ( Alunday, RL; Fletcher, ML; Nash, J; Sarangarm, P; Seifert, SA; Smolinske, SC; Warrick, BJ, 2021) |
"Seizures are physically burdensome and emotionally distressing for patients, families, caregivers, and clinicians." | ( Besbris, JM; Daly, FN; Jones, CA; Kramer, NM; Mehta, AK; Sharma, A; Singhal, D, 2021) |
"First seizures are always challenging for physicians." | ( Carrizosa-Moog, J; Jiménez-Villegas, MJ; Lozano-García, L, 2021) |
"Seizures are common in patients with gliomas; however, the mechanisms of epileptogenesis in gliomas have not been fully understood." | ( Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S, 2021) |
"Myoclonic seizures are the most common seizure type, and 56." | ( Cao, D; Fahlke, C; Guzman, RE; He, H; Peng, J; Sierra-Marquez, J; Stauber, T; Yin, F, 2021) |
"Neonatal seizures are significant cause of neonatal mortality and morbidity." | ( Aggarwal, A; Banerjee, BD; Batra, P; Famra, K, 2022) |
"Epileptic seizures are core symptoms in focal cortical dysplasia (FCD), a disease that often develops in infancy." | ( Akiyama, T; Inoue, Y; Kada, A; Kato, M; Nakagawa, E; Saito, AM; Shiraishi, H; Takahashi, Y; Tohyama, J, 2021) |
"Seizures are common in neonates recovering from birth asphyxia but there is general consensus that current pharmacotherapy is suboptimal and that novel antiseizure drugs are needed." | ( Ala-Kurikka, T; Kaila, K; Kurki, S; Pospelov, AS; Voipio, J, 2021) |
"The risk of seizures is 10-fold higher in patients with Alzheimer's disease than the general population, yet the mechanisms underlying this susceptibility and the effects of these seizures are poorly understood." | ( Barbour, AJ; Eberwine, G; Gourmaud, S; Irwin, DJ; Jensen, FE; O'Brien, WT; Roberts, N; Stewart, DA; Talos, DM; Vassar, R, 2022) |
"Seizures are common in newborn infants with hypoxic-ischemic encephalopathy and are highly associated with adverse neurodevelopmental outcomes." | ( Bennet, L; Cho, KHT; Davidson, JO; Drury, PP; Gunn, AJ; Lear, CA; McDouall, A; Zhou, KQ, 2021) |
"Absence seizures are associated with generalised synchronous 2." | ( Leitch, B; Lyons, NMA; Panthi, S, 2021) |
"Seizures are the outward manifestation of abnormally excessive or synchronous brain activity." | ( Abas, F; Choo, BKM; Faudzi, SMM; Kundap, UP; Samarut, É; Shaikh, MF, 2021) |
"Reflex seizures are consistently evoked by a specific afferent stimulus or by patient activity." | ( Parente, E; Rebessi, E; Riva, A; Romeo, A; Striano, P; Viri, M, 2022) |
"Epileptic seizures are increasingly recognized as part of the clinical phenotype of patients with Alzheimer's disease (AD)." | ( Larner, AJ; Marson, AG, 2022) |
"These seizures are paroxysmal events that result from abnormal neuronal discharges and are categorized into various types based on the clinical manifestations and localization." | ( Karthick, PA; Mathew, J; Ramakrishnan Manuskandan, S; Sivakumaran, N, 2021) |
"Seizures are common in NBIA, particularly in PLAN and BPAN." | ( Emamikhah, M; Fasano, A; Mohammadzadeh, N; Rohani, M; Saiyarsarai, P; Schneider, SA, 2023) |
"Pediatric seizures are a common reason for emergency department visits." | ( Case, SD; Tsao, HS, 2022) |
"Seizures are a disorder caused by structural brain lesions, life-threatening metabolic derangements, or drug toxicity." | ( Andrade, AR; Barbas, LAL; Ferreira, LO; Hamoy, AO; Hamoy, M; Jóia de Mello, V; Leitão, DS; Lopes, DCF; Martins, MFC; Medeiros, NCL; Muto, NA; Santos, VC, 2022) |
"Focal seizures are associated with various co-morbidities." | ( Bhattacharyya, A; Mahajan, SS; Medhi, B; Niraj, N; Prakash, A; Sarma, P, 2022) |
"Epileptic seizures are associated with the overproduction of free radicals in the brain leading to neuronal cell death." | ( Dehdashtian, E; Hosseinzadeh, A; Jafari-Sabet, M; Mehrzadi, S, 2022) |
"Seizures are a common complication that leads to neurological deficits and affects outcomes after aneurysmal subarachnoid haemorrhage (aSAH)." | ( Chen, Y; Fang, M; Hu, X; Li, Y; Pang, B; Sun, B; Wu, H; Wu, P; Wu, Q; Xie, Z; Xu, S; You, C; Zhang, J; Zheng, N, 2022) |
"Neonatal seizures are one of the most challenging problems for experts across the globe." | ( Deshmukh, L; Joshi, A; Londhe, A; Susnerwala, S, 2022) |
"Seizures are the main neurological emergency during the neonatal period and are mostly acute and focal." | ( Bedetti, L; Berardi, A; Casa Muttini, ED; Cavalleri, F; Ferrari, F; Guidotti, I; Lugli, L; Ori, L; Pugliese, M; Roversi, MF; Stefanelli, F, 2022) |
"Seizures are more common in the neonatal period than at any other stage of life." | ( Allison, BJ; Bennet, L; Boyd, BJ; Castillo-Melendez, M; Fahey, MC; Hirst, JJ; Hunt, RW; Jenkin, G; Malhotra, A; McDonald, C; Mihelakis, J; Miller, SL; Nitsos, I; Pham, Y; Sutherland, AE; Walker, DW; Wong, F; Yawno, T, 2022) |
"Seizures are a common clinical manifestation in neuropsychiatric lupus, and our work identifies anti-BC autoantibody activity as a mechanistic cause." | ( Berardi, V; Ginzler, EM; Hanly, JG; Muslimov, IA; Stephenson, S; Tiedge, H, 2022) |
"Seizures are a frequent and diagnostically relevant symptom of ab + AE." | ( Angstwurm, K; Bergh, FT; Bien, CG; Bogarin, Y; Doppler, K; Finke, A; Geis, C; Gerner, ST; Handreka, R; Häusler, M; Hellwig, K; Kaaden, T; Kaufmann, M; Kellinghaus, C; Koertvelyessy, P; Kraft, A; Kunze, A; Lewerenz, J; Leypoldt, F; Madlener, M; Malter, M; Melzer, N; Menge, T; Mues, S; Paliantonis, A; Prüss, H; Rauer, S; Reimann, G; Ringelstein, M; Rostásy, K; Schirotzek, I; Schwabe, J; Sokolowski, P; Suesse, M; Sühs, KW; Surges, R; Tauber, SC; Thaler, F; Urbanek, C; von Podewils, F; Wandinger, KP; Wildemann, B; Zettl, U, 2022) |
"The seizures are generally resistant to traditional antiepileptic drugs and show a dramatic response to high-dose pyridoxine." | ( Çavdartepe, BE; İpek, R; Kor, D; Okuyaz, Ç, 2022) |
"Absence seizures are hyperexcitations within the cortico-thalamocortical (CTC) network, however the underlying causative mechanisms at the cellular and molecular level are still being elucidated and appear to be multifactorial." | ( Adotevi, NK; Hassan, M; Leitch, B, 2022) |
"Seizures are a complex of transient signs and symptoms resulting from abnormal, simultaneous, and excessive activity of a population of neurons, and they can be both a cause and a consequence of oxidative stress." | ( López-Meraz, ML; Pérez-Severiano, F; Ramos-Riera, KP, 2023) |
"Seizures are suspected to be side effects of antipsychotics." | ( Efthimiou, O; Leucht, S; Reichelt, L; Schneider-Thoma, J, 2023) |
"Seizures are common in palliative care patients and its control is essential in the management of these patients as it helps to reduce suffering at the end of life." | ( Diaz-Forero, AF; Estrada, J; Gaviria-Carrillo, M; Mora-Muñoz, L; Rodríguez, JH; Torres-Ballesteros, V; Vargas-Osorio, J; Vélez Van Meerbeke, A, 2023) |
"Seizures are considered to be the most common symptom encountered in emergency- rushed tramadol-poisoned patients; accounting for 8% of the drug-induced seizure cases." | ( El-Bassyouni, GT; Elgohary, R; ElShebiney, SA; Hamzawy, EMA; Kenawy, SH, 2023) |
"Seizures are a frequent pathophysiological feature of malignant glioma." | ( Aiba, I; Cervantes, A; Cocito, C; Curry, RN; Deneen, B; Gavvala, J; Greenfield, JP; Huang-Hobbs, E; Jalali, A; Ko, Y; Lozzi, B; McDonald, MF; Meyer, J; Mohila, C; Noebels, J; Rao, G; Rosenbaum, A; Serin Harmanci, A, 2023) |
"Seizures are life-threatening complications of neuropsychiatric systemic lupus erythematosus (NPSLE) and are often associated with poor outcomes." | ( Jiang, W; Shi, Y; Wu, J; Zhang, J; Zhang, L, 2023) |
"Seizures are common neurological emergencies in the elderly that are frequently provoked." | ( Alattiya, MK; Hammamy, RA; Joudeh, AI, 2023) |
"Seizures are among the most common clinical signs in people with glioblastoma." | ( Cole, AJ; Dietrich, J; Sokolov, E, 2023) |
"Neonatal seizures are severe pathologies which may result in long-term neurological consequences." | ( Gataulina, E; Gerasimova, E; Khalilov, I; Kurmashova, E; Sitdikova, GF; Yakovlev, AV, 2023) |
"Urgent seizures are a medical emergency for which new therapies are still needed." | ( Asensio, M; Campos, D; Castillo, A; Chavarria, B; Escalza, I; Falip, M; Fernández-Cabrera, A; Garcés, M; García-Morales, I; Gifreu, A; Giménez, J; Guillén, V; Hampel, K; Hernández Pérez, G; Juiz-Fernández, Á; Martínez, AB; Massot, M; Montoya, J; Parejo-Carbonell, B; Rocamora, R; Rodriguez-Osorio, X; Rubio-Nazábal, E; Ruiz-Giménez, J; Santamarina, E; Sayas, D; Villanueva, V, 2023) |
"Seizures are a common neurological disorder that affects people of all ages." | ( Fathi, E; Panahi, Y; Shafiian, MA, 2023) |
"Seizures are common in neonates, but there is substantial management variability." | ( Abend, NS; Auvin, S; Boylan, G; Brigo, F; Cilio, MR; De Vries, LS; Elia, M; Espeche, A; Hahn, CD; Hartmann, H; Inder, T; Jette, N; Kakooza-Mwesige, A; Mader, S; Mizrahi, EM; Moshé, SL; Nagarajan, L; Noyman, I; Nunes, ML; Pressler, RM; Samia, P; Shany, E; Shellhaas, RA; Subota, A; Triki, CC; Tsuchida, T; Vinayan, KP; Wilmshurst, JM; Yozawitz, EG, 2023) |
"Classically, seizures are assumed to occur at random." | ( Anderson, C; Bagshaw, AP; Cook, MJ; D'Souza, W; Lightman, SL; Marinelli, I; Seneviratne, U; Terry, JR; Walker, JJ; Woldman, W, 2023) |
"Seizures are associated with a decrease in γ-aminobutyric type A acid receptors (GABAaRs) on the neuronal surface, which may be regulated by enhanced internalization of GABAaRs." | ( Huang, H; Li, S; Lu, Y; Ma, M; Sun, L; Wei, X; Wu, Y; Ye, L, 2023) |