Page last updated: 2024-10-23

bethanechol and Seizures

bethanechol has been researched along with Seizures in 2 studies

Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Microinjections of the cholinergic agonists, carbachol and bethanechol, either into the amygdala or into the dorsal hippocampus produced sustained limbic seizures and brain damage in rats."3.66Cholinomimetics produce seizures and brain damage in rats. ( Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turski, WA2
Cavalheiro, EA1
Turski, L2
Kleinrok, Z2
Czuczwar, SJ1

Other Studies

2 other studies available for bethanechol and Seizures

ArticleYear
Intrahippocampal bethanechol in rats: behavioural, electroencephalographic and neuropathological correlates.
    Behavioural brain research, 1983, Volume: 7, Issue:3

    Topics: Acetylcholine; Animals; Automatism; Behavior, Animal; Bethanechol; Bethanechol Compounds; Electroenc

1983
Cholinomimetics produce seizures and brain damage in rats.
    Experientia, 1983, Dec-15, Volume: 39, Issue:12

    Topics: Amygdala; Animals; Bethanechol; Bethanechol Compounds; Brain; Brain Diseases; Carbachol; Hippocampus

1983