Page last updated: 2024-09-03

safinamide and Seizures

safinamide has been researched along with Seizures in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP1
Cummins, TR; Dustrude, ET; Khanna, R; Kohn, H; Torregrosa, R; Yang, XF1
Dustrude, ET; Khanna, R; Kohn, H; Park, KD; Ripsch, MS; Wang, Y; White, FA; Yang, XF1
Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M1
Algate, C; Beard, D; Fariello, RG; Maj, R; Marrari, P; Salvati, P1

Other Studies

5 other study(ies) available for safinamide and Seizures

ArticleYear
Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Acetamides; Alanine; Amides; Amino Acids; Animals; Anticonvulsants; Benzylamines; Drug Evaluation, Preclinical; Lacosamide; Mice; Pain; Rats; Seizures; Structure-Activity Relationship; Treatment Outcome

2010
Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Acetamides; Administration, Oral; Amides; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Electroshock; HEK293 Cells; Humans; Injections, Intraperitoneal; Male; Mice; Neurons; Patch-Clamp Techniques; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2015
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamid
    ACS chemical neuroscience, 2015, Feb-18, Volume: 6, Issue:2

    Topics: Acetamides; Alanine; Analgesics; Animals; Anticonvulsants; Benzylamines; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Female; Formaldehyde; Lacosamide; Male; Membrane Potentials; Mice; Neuralgia; Neurons; Patch-Clamp Techniques; Rats, Sprague-Dawley; Seizures; Tibial Nerve; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2015
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
    Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4

    Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine

1998
Acute behavioral and EEG effects of NW-1015 on electrically-induced afterdischarge in conscious monkeys.
    Epilepsy research, 2000, Volume: 39, Issue:1

    Topics: Alanine; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Electric Stimulation; Electroencephalography; Macaca fascicularis; Male; Phenytoin; Seizures

2000