ono 1078 has been researched along with Seizures in 2 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Kainate-induced seizures are accompanied by leukotriene formation, and are reduced by inhibitors of LOX/COX pathway." | 1.40 | Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood-brain barrier dysfunction. ( Arroyo, DS; Iribarren, P; Jesse, AC; Lenz, QF; Marafiga, JR; Masson, CJ; Mello, CF; Poersch, AB; Reschke, CR; Temp, FR, 2014) |
| "Innovative treatments of epileptic seizures are needed to improve the outcome of epilepsy." | 1.39 | Open study of pranlukast add-on therapy in intractable partial epilepsy. ( Ikeda, H; Imai, K; Kubota, Y; Susa, F; Takahashi, Y; Yamazaki, E, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lenz, QF | 1 |
| Arroyo, DS | 1 |
| Temp, FR | 1 |
| Poersch, AB | 1 |
| Masson, CJ | 1 |
| Jesse, AC | 1 |
| Marafiga, JR | 1 |
| Reschke, CR | 1 |
| Iribarren, P | 1 |
| Mello, CF | 1 |
| Takahashi, Y | 1 |
| Imai, K | 1 |
| Ikeda, H | 1 |
| Kubota, Y | 1 |
| Yamazaki, E | 1 |
| Susa, F | 1 |
2 other studies available for ono 1078 and Seizures
| Article | Year |
|---|---|
Cysteinyl leukotriene receptor (CysLT) antagonists decrease pentylenetetrazol-induced seizures and blood-brain barrier dysfunction.
Topics: Acetates; Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Capillary Permeability; Chromones; C | 2014 |
Open study of pranlukast add-on therapy in intractable partial epilepsy.
Topics: Adolescent; Anticonvulsants; Biomarkers; CD4-Positive T-Lymphocytes; Cell Count; Child; Chromones; C | 2013 |