Page last updated: 2024-11-07

estrone and Seizures

estrone has been researched along with Seizures in 4 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Pre-treatment with estrone (250-1000 micrograms/kg) at 24 and 2 hours before kainate (40 mg/kg) administration significantly decreased both the percentage of animals with clonic seizures and their mortality (the latter at a dose of 1000 micrograms/kg only)."5.31Estrone, but not 17 beta-estradiol, attenuates kainate-induced seizures and toxicity in male mice. ( Budziszewska, B; Jaworska-Feil, L; Kajta, M; Kubera, M; Lasoń, W; Leśkiewicz, M, 2001)
"Pre-treatment with estrone (250-1000 micrograms/kg) at 24 and 2 hours before kainate (40 mg/kg) administration significantly decreased both the percentage of animals with clonic seizures and their mortality (the latter at a dose of 1000 micrograms/kg only)."1.31Estrone, but not 17 beta-estradiol, attenuates kainate-induced seizures and toxicity in male mice. ( Budziszewska, B; Jaworska-Feil, L; Kajta, M; Kubera, M; Lasoń, W; Leśkiewicz, M, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mack, JT1
Brown, CB1
Garrett, TE1
Uys, JD1
Townsend, DM1
Tew, KD1
ROSADINI, G1
BERNARDINI, G1
Budziszewska, B1
Leśkiewicz, M1
Kubera, M1
Jaworska-Feil, L1
Kajta, M1
Lasoń, W1
Lange, SC1
Julien, RM1

Other Studies

4 other studies available for estrone and Seizures

ArticleYear
Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:6

    Topics: Animals; ATP-Binding Cassette Transporters; Biotransformation; Disease Susceptibility; Estradiol; Es

2012
[Experimental research on the relation between female sex steroids and epilepsy. I. Action of progesterone and estrone sulfate on the metrazole test].
    Bollettino della Societa italiana di biologia sperimentale, 1962, Dec-31, Volume: 38

    Topics: Epilepsy; Estrone; Female; Pentylenetetrazole; Progesterone; Seizures; Steroids

1962
Estrone, but not 17 beta-estradiol, attenuates kainate-induced seizures and toxicity in male mice.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2001, Volume: 109, Issue:3

    Topics: Animals; Estradiol; Estrogen Antagonists; Estrone; Hippocampus; Immunity; Kainic Acid; Male; Mice; N

2001
Re-evaluation of estrogen-induced cortical and thalamic paroxysmal EEG activity in the cat.
    Electroencephalography and clinical neurophysiology, 1978, Volume: 44, Issue:1

    Topics: Animals; Cats; Cerebral Cortex; Decerebrate State; Disease Models, Animal; Dose-Response Relationshi

1978