3,4-dihydroxyphenylacetic acid has been researched along with Seizures in 16 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The experimental model of seizures which depends upon methionine sulfoximine (MSO) simulates the most striking form of human epilepsy." | 3.79 | Monoamines and glycogen levels in cerebral cortices of fast and slow methionine sulfoximine-inbred mice. ( Boissonnet, A; Cloix, JF; Hévor, T; Landemarre, L, 2013) |
| " Rats that did not become hyperthermic when dosed with 15 mg/kg AMPH in a cold environment (10 degrees C) exhibited some hyperactivity and stereotypic behavior, but not overt convulsive behavior." | 1.31 | Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine. ( Bowyer, JF; Tor-Agbidye, J; Yamamoto, B, 2001) |
| "In the seizure animals, neurotransmitter metabolites remained at low levels, as if the hypoxia had continued after the period of ischemia, inhibiting monoamine oxidase activity and, perhaps, neurotransmitter recapture." | 1.29 | Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures. ( Allain, H; Bellissant, E; Bentué-Ferrer, D; Decombe, R, 1994) |
| "The data suggest that seizure-prone BALB/c mice have a deficiency in intracellular content of both excitatory and inhibitory amino acids." | 1.29 | Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice. ( Alexiuk, NA; Green-Johnson, J; Ryan, E; Vriend, J, 1993) |
| "Isoguvacine pre-treatment prevented the increase in DOPAC concentrations in the median eminence produced by SR 95531." | 1.29 | GABAergic regulation of tuberoinfundibular dopaminergic neurons in the male rat. ( Goudreau, JL; Lookingland, KJ; Moore, KE; Wagner, EJ, 1994) |
| "Convulsions are frequently observed in severe, acute cyanide intoxication." | 1.29 | Estimation of the convulsive effect of cyanide in rats. ( Cassel, GE, 1995) |
| "During tonic convulsions, the amplitude of the DOPAC oxidation peak significantly decreased to 75% of the peak height recorded prior to the injection of PTZ, and the minimum lasted for about 30 min; then the mean curve slowly recovered to the control level within 60 min." | 1.27 | Determination of neurotransmitter release into the caudate nucleus during convulsions induced by pentylenetetrazole using in vivo differential pulse voltammetry. ( Fujikawa, N; Mori, A; Shirasu, A; Yamamoto, M; Yokoi, I, 1986) |
| "All animals suffered tonic convulsions at 18." | 1.27 | Convulsant effect of lindane and regional brain concentration of GABA and dopamine. ( Gelpí, E; Rodríguez-Farré, E; Suñol, C; Tusell, JM, 1988) |
| "An investigation was made into the relationship between dopaminergic and EEG effects of gamma-butyrolactone (GBL) by comparing time-course and dose-response studies of these two actions of gamma-butyrolactone in rats implanted with permanent cortical electrodes." | 1.26 | An investigation of the relationship between the dopaminergic and electroencephalographic effects of gamma-butyrolactone. ( Snead, OC, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boissonnet, A | 1 |
| Hévor, T | 1 |
| Landemarre, L | 1 |
| Cloix, JF | 1 |
| Loke, WK | 1 |
| Sim, MK | 1 |
| Go, ML | 1 |
| Snead, OC | 1 |
| Bentué-Ferrer, D | 1 |
| Bellissant, E | 1 |
| Decombe, R | 1 |
| Allain, H | 1 |
| Vriend, J | 2 |
| Alexiuk, NA | 2 |
| Green-Johnson, J | 1 |
| Ryan, E | 1 |
| el-Etri, MM | 2 |
| Ennis, M | 2 |
| Jiang, M | 1 |
| Shipley, MT | 2 |
| Wagner, EJ | 1 |
| Goudreau, JL | 1 |
| Moore, KE | 1 |
| Lookingland, KJ | 1 |
| Cassel, GE | 1 |
| Tor-Agbidye, J | 1 |
| Yamamoto, B | 1 |
| Bowyer, JF | 1 |
| Bourne, JA | 1 |
| Fosbraey, P | 1 |
| Halliday, J | 1 |
| Nickell, WT | 1 |
| Skau, KA | 1 |
| Zis, AP | 1 |
| Nomikos, GG | 1 |
| Damsma, G | 1 |
| Fibiger, HC | 1 |
| Mori, A | 2 |
| Hiramatsu, M | 1 |
| Kabuto, H | 1 |
| Marescau, B | 1 |
| Yokoi, I | 1 |
| Yamamoto, M | 1 |
| Fujikawa, N | 1 |
| Shirasu, A | 1 |
| Suñol, C | 1 |
| Tusell, JM | 1 |
| Gelpí, E | 1 |
| Rodríguez-Farré, E | 1 |
16 other studies available for 3,4-dihydroxyphenylacetic acid and Seizures
| Article | Year |
|---|---|
Monoamines and glycogen levels in cerebral cortices of fast and slow methionine sulfoximine-inbred mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Disease Models, Animal; Glycoge | 2013 |
Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analysis of Variance; Animals; Anticonvulsants; Atrop | 2005 |
An investigation of the relationship between the dopaminergic and electroencephalographic effects of gamma-butyrolactone.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Anticonvulsants; Cerebral Cortex; Corpus S | 1982 |
Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyin | 1994 |
Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Biogenic Monoamines; Caudate Nucleus; Dopamine | 1993 |
Pilocarpine-induced convulsions in rats: evidence for muscarinic receptor-mediated activation of locus coeruleus and norepinephrine release in cholinolytic seizure development.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Locu | 1993 |
GABAergic regulation of tuberoinfundibular dopaminergic neurons in the male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Dopamine; GABA Agonists; GABA Antagonists; gamma- | 1994 |
Estimation of the convulsive effect of cyanide in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopa | 1995 |
Lamotrigine inhibits the in situ activity of tyrosine hydroxylase in striatum of audiogenic seizure-prone and audiogenic seizure-resistant Balb/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Animals; Corpus Striatum; Dopamine; Enzyme Inh | 1997 |
Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amygdala; Animals; Behavior, Animal; Chromatography, Hi | 2001 |
Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Benzazepines; Corpus Striatum; Dopamine; Dop | 2001 |
Brain norepinephrine reductions in soman-intoxicated rats: association with convulsions and AChE inhibition, time course, and relation to other monoamines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Biogenic Amines; Brain; Cholinesterase In | 1992 |
In vivo neurochemical effects of electroconvulsive shock studied by microdialysis in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Brain Chemistry; Choline; Convulsants; Corpu | 1991 |
Effects of emotional stress on E1-mouse convulsions, and their biochemical background.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Homovanillic Acid; Hydroxyindole | 1986 |
Determination of neurotransmitter release into the caudate nucleus during convulsions induced by pentylenetetrazole using in vivo differential pulse voltammetry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Electroencephalography; Hydroxyi | 1986 |
Convulsant effect of lindane and regional brain concentration of GABA and dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Hexachl | 1988 |