Page last updated: 2024-08-21

hydantoins and Seizures

hydantoins has been researched along with Seizures in 103 studies

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-199088 (85.44)18.7374
1990's1 (0.97)18.2507
2000's7 (6.80)29.6817
2010's6 (5.83)24.3611
2020's1 (0.97)2.80

Authors

AuthorsStudies
Byrtus, H; Czopek, A; Góra, M; Obniska, J; Rapacz, A; Rychtyk, J; Sałat, K; Zagórska, A1
Abd-Allah, WH; Aboul-Enein, MN; Aboutabl, ME; El-Azzouny, AA; Hassan, RM1
Kumar, CSA; Mahadevaiah, KM; Prasad, SBB; Raj, CSA; Ramesha, KC; Veeresh, B1
Bastlund, JF; Didriksen, M; Halje, P; Nielsen, J; Petersson, P; Thelin, J1
Ahmed, J; Chaudhury, JR; Das, UN; Hasan, Q; Kanjilal, S; Ponnala, S; Rama Rao, B; Rao, KP1
CAHEN, RL1
Byrtus, H; Kamiński, K; Karolak-Wojciechowska, J; Obniska, J; Pawłowski, M; Szczesio, M1
He, X; Hu, X; Pan, Y; Qiu, G; Wu, W; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M1
GOODMAN, LS; SWINYARD, EA; TOMAN, JE1
GOODMAN, LS; SWINYARD, EA1
Byrtus, H; Czopek, A; Kamiński, K; Obniska, J1
Brandt, C; Dannhardt, G; Jansen, M; Löscher, W; Potschka, H1
HAYS, AL; HILL, TS; WONG, YT1
BROWN, WC; GOODMAN, LS; SWINYARD, EA1
CHEN, G; ENSOR, CR2
BROWN, WC; GOODMAN, LS; SCHIFFMAN, DO; SWINYARD, EA1
STILLE, G1
BOGUE, JY; CARRINGTON, HC1
HASHINO, S; HORIGUCHI, T; KOYASU, Y; YOSHII, N1
PETERS, JJ; VONDERAHE, AR1
REDER, EL1
PETERMAN, MG1
DREW, AL1
MURPHY, JT; SCHWAB, RS1
QUADBECK, G; ROHM, E1
GOODMAN, LS; SWINYARD, EA; TEDESCHI, DH1
CASPERS, H; WEHMEYER, H1
SHAPIRO, M1
McWILLIAM, PK1
BALDWIN, RW1
BOHNER, B; CHEN, G; ENSOR, CR1
CHRISTY, NP; HOFMANN, AD1
UEHLEKE, H1
SPUDIS, EV; STROBOS, RR1
CARTER, WW; ESSIG, CF1
FUKAI, H; NAKAI, S; SATO, S; WATANABE, S1
DE SALVA, S1
TAZZER, AU1
BARO, WZ1
GOLDMAN, D; SCHYNOLL, G1
SOBUE, I1
MACGREGOR, M1
JONGMANS, JW1
FOIS, A; MALANDRINI, F1
PENIN, H1
LORGE, M1
BERTAMINO, F; VENTO, R1
KIORBOE, E1
ARAI, S; GOTO, Y; SEKIBA, K; TAEN, S1
AOKI, Y; FUKUI, S; KISHI, Y; MANMARU, S1
BATINI, C; MANTEGAZZINI, P1
BONNY-CASTLE, DD; COSTA, PJ; GLASER, GH1
ALEDORT, LM; MADSEN, JA; MILLICHAP, JG1
OTTOSSON, JO1
FINGER, KF; FUNDERBURK, WH; P'AN, SY1
JESSERER, H1
RUSKIN, DB1
BORKOWSKI, W; HOLT, WL1
LITTLE, SC; LITTLJOHN, WS; McLALLEN, CD1
SANDBERG, F1
WOODBURY, DM1
Chui, WK; Thenmozhiyal, JC; Wong, PT1
ORDWAY, GL; PURO, HE1
MARSH, C; MILLER, VJ1
FRANK, ME; PRICE, WC1
Batts, TW; Brown, ML; Davis, GC; Hartmann, HA; Jones, PJ; Ko, SH; Lenkowski, PW; McCusker, AK; Patel, MK; Smith, MD; Taylor, CH; White, HS1
Hu, X; Ke, X; Li, R; Pan, Y; Qiu, G; Wu, L; Xu, W; Xu, Z; Zhu, Q1
Graziani, LJ; Korberly, BH; Mrazik, TJ1
Boehm, R; Carter, CA; Helms, RA1
Gutkowska, B; Wasiak, J1
Kamińska, A; Rydzik, E; Szadowska, A1
Alexander, GJ; Chatterjie, N; Sinha, B1
Alexander, GJ; Chatterjie, N2
Chodkowska, A; Kleinrok, Z; Korohoda, MJ; Kozicka, M1
Diuguid, CA; Mehta, NB; Soroko, FE1
Kohn, H; LeTiran, A; Stables, JP1
Aleksiev, B; Lazarova, M; Naydenova, E; Pencheva, N; Popova, J; Stoyanov, N1
Nogen, AG1
Jacobs, HG; Selle, G1
García Sacristán, A; Illera Martín, M; Sanz Sánchez, F1
Denhoff, E; Feldman, S; Holden, W; Litchman, H; Smith, MG1
O'Dea, MH; Reinhard, JF; Samour, CM; Vida, JA1
Ojemann, LM; Troupin, AS1
Leppik, IE1
Alexander, GJ; Chatterjie, N; Laorden, ML; Puig, MM1
Degen, R; Helling, R1
Reinken, L1
Rümke, CL1
Friedlander, WJ1
Andermann, F; Robb, JP1
Wildhack, R1
Westphal, P1
Tchicaloff, M1
Saad, SF1
Aicardi, J1
Chang, T; Glazko, AJ; Savory, A1
Blackburn, WH; Napoli, MD; Wallin, RF1
Hata, T; Kita, T; Murakami, T; Okage, T1
Blum, B; Elazar, Z1
McGregor, JG; Schreiber, MM1
Fujimoto, K; Hirooka, T; Nakamura, K; Nakatsuji, K; O'Hashi, K; Ose, S1

Reviews

3 review(s) available for hydantoins and Seizures

ArticleYear
[Drug induced gingival hyperplasia and its therapy].
    Deutsche zahnarztliche Zeitschrift, 1976, Volume: 31, Issue:8

    Topics: Adolescent; Endocrine System Diseases; Female; Gingival Hyperplasia; Gingivectomy; Humans; Hydantoins; Seizures

1976
[Scope and effect of vitamin B6 in newborn infants and children].
    Padiatrie und Padologie, 1974, Volume: 9, Issue:4

    Topics: Amino Acids; Anemia, Hypochromic; Aspartate Aminotransferases; Brain; Coenzymes; Drug Antagonism; Female; Gestational Age; Humans; Hydantoins; Infant, Newborn; Iron; Isoniazid; Maternal-Fetal Exchange; Nutritional Physiological Phenomena; Nutritional Requirements; Penicillamine; Phosphotransferases; Pregnancy; Pyridoxal Phosphate; Pyridoxine; Seizures; Succinimides; Tryptophan; Vitamin B Deficiency; Xanthurenates

1974
Epilepsy.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Adolescent; Animals; Barbiturates; Brain Neoplasms; Cell Membrane Permeability; Central Nervous System Stimulants; Cerebrovascular Disorders; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Ethanol; Fever; Humans; Hydantoins; Hypoxia, Brain; Infant; Infant, Newborn; Infections; Mental Disorders; Metabolic Diseases; Myoclonus; Neurocognitive Disorders; Radiography; Rehabilitation, Vocational; Seizures; Social Adjustment; Synaptic Transmission

1968

Trials

2 trial(s) available for hydantoins and Seizures

ArticleYear
Effect of dantrolene sodium on the incidence of seizures in children with spasticity.
    Child's brain, 1979, Volume: 5, Issue:4

    Topics: Adolescent; Anticonvulsants; Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Dantrolene; Double-Blind Method; Electroencephalography; Epilepsy; Evoked Potentials; Humans; Hydantoins; Infant; Muscle Spasticity; Seizures

1979
Treatment of spastic cerebral-palsied children with sodium dantrolene.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:6

    Topics: Cerebral Palsy; Child; Child, Preschool; Clinical Trials as Topic; Dantrolene; Female; Humans; Hydantoins; Infant; Male; Seizures; Spasm

1975

Other Studies

98 other study(ies) available for hydantoins and Seizures

ArticleYear
Synthesis and pharmacological evaluation of novel N-Mannich bases derived from 5,5-diphenyl and 5,5-di(propan-2-yl)imidazolidine-2,4-dione core.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazolidines; Mannich Bases; Mice; Molecular Structure; Oxaliplatin; Pain; Rats; Seizures; Structure-Activity Relationship

2019
Design and synthesis of novel parabanic acid derivatives as anticonvulsants.
    Bioorganic chemistry, 2020, Volume: 94

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Hepatocytes; Hydantoins; Male; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship

2020
Synthesis and Evaluation of Novel Diazaspiro Hydantoins as Potential Anticonvulsants.
    Central nervous system agents in medicinal chemistry, 2017, Volume: 17, Issue:3

    Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Hydantoins; Male; Rats; Rats, Wistar; Seizures

2017
The translationally relevant mouse model of the 15q13.3 microdeletion syndrome reveals deficits in neuronal spike firing matching clinical neurophysiological biomarkers seen in schizophrenia.
    Acta physiologica (Oxford, England), 2017, Volume: 220, Issue:1

    Topics: Animals; Brain; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 15; Disease Models, Animal; Electrophysiology; Evoked Potentials, Auditory; Humans; Hydantoins; Intellectual Disability; Male; Mice; Neurons; Pyridines; Schizophrenia; Seizures

2017
Effect of polyunsaturated fatty acids on diphenyl hydantoin-induced genetic damage in vitro and in vivo.
    Prostaglandins, leukotrienes, and essential fatty acids, 2009, Volume: 80, Issue:1

    Topics: Animals; Anticonvulsants; Dietary Supplements; DNA; DNA Damage; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Humans; Hydantoins; Lymphocytes; Micronucleus Tests; Seizures

2009
On the anticonvulsant activity of various nitrogen heterocycles; alkylthioetherbarbiturates and phenylalkylthiomethylhydantoins.
    The Journal of pharmacology and experimental therapeutics, 1946, Volume: 88, Issue:4

    Topics: Anticonvulsants; Barbital; Barbiturates; Hydantoins; Nitrogen; Seizures; Spasm

1946
Design, synthesis, and anticonvulsant activity of new N-Mannich bases derived from spirosuccinimides and spirohydantoins.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Anticonvulsants; Electroshock; Hydantoins; Male; Mannich Bases; Mice; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Sodium Channels; Spiro Compounds; Succinimides

2010
Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Mice; Molecular Structure; Seizures; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship

2010
Studies on the anticonvulsant properties of diphenylhydantoin.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Anticonvulsants; Hydantoins; Phenytoin; Seizures

1946
Laboratory assay of anticonvulsant potency of some hydantoinates.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Anticonvulsants; Biological Assay; Hydantoins; Laboratories; Seizures

1946
Synthesis and anticonvulsant activity of new n-mannich bases derived from 5-cyclopropyl-5-phenyl-hydantoins.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:4

    Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Hydantoins; Male; Mannich Bases; Mice; Molecular Structure; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship

2011
Hydantoin-substituted 4,6-dichloroindole-2-carboxylic acids as ligands with high affinity for the glycine binding site of the NMDA receptor.
    Journal of medicinal chemistry, 2003, Jan-02, Volume: 46, Issue:1

    Topics: Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Brain; Electroshock; Female; Glycine; Hydantoins; In Vitro Techniques; Indoles; Ligands; Mice; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Swine

2003
The control with mesantoin on convulsive seizures due to neurosyphilis; clinical and electroencephalographic studies.
    The Journal of nervous and mental disease, 1952, Volume: 116, Issue:3

    Topics: Electroencephalography; Epilepsy; Humans; Hydantoins; Mephenytoin; Neurosyphilis; Seizures

1952
Comparative assays of antiepileptic drugs in mice and rats.
    The Journal of pharmacology and experimental therapeutics, 1952, Volume: 106, Issue:3

    Topics: Animals; Anticonvulsants; Barbiturates; Biological Assay; Hydantoins; Mice; Oxazoles; Rats; Seizures; Urea

1952
The combined anticonvulsant activity and toxicity of dilantin and N-methyl-5-phenylsuccinimide.
    The Journal of laboratory and clinical medicine, 1953, Volume: 41, Issue:1

    Topics: Anticonvulsants; Hydantoins; Phenytoin; Seizures

1953
Comparative assay of an antiepileptic drugs by psychomotor seizure test and minimal electroshock threshold test.
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 107, Issue:3

    Topics: Anticonvulsants; Barbiturates; Electroshock; Humans; Hydantoins; Seizures

1953
[The significance of central excitation for the inhibition of electric convulsions].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1953, Volume: 217, Issue:1

    Topics: Barbiturates; Central Nervous System Stimulants; Hydantoins; Seizures

1953
The evaluation of "mysoline," a new anticonvulsant drug.
    British journal of pharmacology and chemotherapy, 1953, Volume: 8, Issue:2

    Topics: Anticonvulsants; Hydantoins; Primidone; Seizures

1953
Studies on the effect of anticonvulsants on the electroshock seizure induced through condenser discharge method.
    Folia psychiatrica et neurologica japonica, 1953, Volume: 6, Issue:4

    Topics: Anticonvulsants; Electricity; Electroshock; Hydantoins; Mephenesin; Seizures

1953
Electroencephalographic studies, induced seizures, and their modification by phenobarbital, dilantin, and phenurone, in the salamanders, Triturus viridescens and Ambystoma tigrinum.
    Electroencephalography and clinical neurophysiology, 1954, Volume: 6, Issue:2

    Topics: Ambystoma; Animals; Anticonvulsants; Barbiturates; Benzeneacetamides; Electroencephalography; Humans; Hydantoins; Notophthalmus viridescens; Phenobarbital; Phenytoin; Seizures; Urea; Urodela

1954
Evaluation of mebaroin in the treatment of grand mal.
    New York state journal of medicine, 1954, Jun-01, Volume: 54, Issue:11

    Topics: Barbiturates; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Seizures

1954
Nuvarones in the treatment of convulsive disorders; clinical note.
    Pediatrics, 1954, Volume: 14, Issue:4

    Topics: Hydantoins; Seizures

1954
Anticonvulsant drugs.
    Postgraduate medicine, 1955, Volume: 18, Issue:4

    Topics: Anticonvulsants; Barbiturates; Child; Humans; Hydantoins; Infant; Seizures

1955
Diphenylhydantoin (dilantin) sodium used parenterally in control of convulsions; a five-year report.
    Journal of the American Medical Association, 1956, Feb-04, Volume: 160, Issue:5

    Topics: Anions; Hydantoins; Ions; Phenytoin; Seizures; Sodium; Sodium, Dietary

1956
[Constitution specificity of the anticonvulsive action of 5-p-chlorphenyl-5-methylhydantoin in audiogenic convulsions in rats].
    Arzneimittel-Forschung, 1956, Volume: 6, Issue:9

    Topics: Animals; Epilepsy, Reflex; Hydantoins; Rats; Seizures

1956
Postictal recovery in normal and diphenylhydantoin (dilantin)-treated mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1956, Volume: 93, Issue:2

    Topics: Animals; Hydantoins; Mice; Phenytoin; Physiological Phenomena; Seizures

1956
[Effect of diphenylhydantoin on convulsion excitability of the cerebral cortex].
    Zeitschrift fur die gesamte experimentelle Medizin, 1957, Volume: 129, Issue:1

    Topics: Cerebral Cortex; Humans; Hydantoins; Phenytoin; Psychomotor Agitation; Seizures

1957
Acceleration of gingival wound healing in non-epileptic patients receiving diphenylhydantoin sodium (dilantin, epanutin).
    Experimental medicine and surgery, 1958, Volume: 16, Issue:1

    Topics: Acceleration; Gingiva; Humans; Hydantoins; Phenytoin; Seizures; Sodium; Wound Healing

1958
Intravenous phenytoin sodium in continuous convulsions in children.
    Lancet (London, England), 1958, Nov-29, Volume: 2, Issue:7057

    Topics: Child; Humans; Hydantoins; Infant; Phenytoin; Seizures

1958
The use of peganone in uncontrolled seizure patients.
    Bulletin of the School of Medicine (Baltimore, Md.), 1959, Volume: 44, Issue:1

    Topics: Epilepsy; Hydantoins; Seizures

1959
Anticonvulsant effect of dilantin sodium by intravenous administration in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1959, Volume: 100, Issue:1

    Topics: Administration, Intravenous; Animals; Anticonvulsants; Hydantoins; Mice; Phenytoin; Seizures; Sodium

1959
Effects of diphenylhydantoin upon adrenal cortical function in man.
    Neurology, 1959, Volume: 9, Issue:4

    Topics: Adrenal Cortex; Humans; Hydantoins; Phenytoin; Seizures

1959
[Anticonvulsive effect of 2-amino-5-(5,5-diphenyl-3-hydantoyl)-valeric acid after intravenous administration in animal experiments].
    Der Nervenarzt, 1959, Apr-20, Volume: 30, Issue:4

    Topics: Administration, Intravenous; Animal Experimentation; Animals; Biphenyl Compounds; Hydantoins; Pentanoic Acids; Seizures

1959
Effect of-anticonvulsant drugs on cortical and subcortical seizure discharges in cats.
    Archives of neurology, 1960, Volume: 2

    Topics: Animals; Anticonvulsants; Cats; Epilepsy; Humans; Hydantoins; Phenobarbital; Seizures

1960
Failure of diphenylhydantoin in preventing barbiturate withdrawal convulsions in the dog.
    Neurology, 1962, Volume: 12

    Topics: Animals; Barbiturates; Dogs; Hydantoins; Phenytoin; Seizures; Substance Withdrawal Syndrome

1962
[Use of parenteral dilantin sodium in control of neurosurgical convulsive seizure].
    No to shinkei = Brain and nerve, 1962, Volume: 14

    Topics: Epilepsy; Hydantoins; Neurosurgery; Neurosurgical Procedures; Phenytoin; Seizures; Sodium

1962
Effect of drugs on EST in various endocrine deficient states.
    Archives internationales de pharmacodynamie et de therapie, 1963, Apr-01, Volume: 142

    Topics: Adrenalectomy; Diphenhydramine; Ephedrine; Hydantoins; Hypophysectomy; Lysergic Acid Diethylamide; Meprobamate; Phenobarbital; Reserpine; Seizures; Serotonin; Thyroidectomy

1963
[MEDICAL TREATMENT OF "GRAND MAL" CONVULSIVE DISORDERS].
    Le Scalpel, 1963, Oct-12, Volume: 116

    Topics: Epilepsy; Epilepsy, Tonic-Clonic; Hydantoins; Hydroxyzine; Seizures; Toxicology

1963
METHETOIN, A NEW ANTICONVULSANT.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Adolescent; Alcoholism; Anticonvulsants; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Intellectual Disability; Migraine Disorders; Psychotic Disorders; Seizures

1964
THE EFFECT OF CHLORDIAZEPOXIDE ON CONVULSIVE DISORDER.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Alcoholism; Anticonvulsants; Brain Diseases; Chlordiazepoxide; Electroencephalography; Epilepsy; Hydantoins; Intellectual Disability; Neurosyphilis; Schizophrenia; Seizures; Toxicology

1964
[EMERGENCY MANAGEMENT OF CONVULSIONS].
    Naika. Internal medicine, 1964, Volume: 13

    Topics: Barbiturates; Eclampsia; Female; Humans; Hydantoins; Physiology; Pregnancy; Rabies; Rabies Vaccines; Seizures

1964
EPILEPSY IN CHILDHOOD: CLASSIFICATION AND TREATMENT.
    Postgraduate medical journal, 1964, Volume: 40

    Topics: Acetazolamide; Adrenal Cortex Hormones; Angiomatosis; Barbiturates; Child; Classification; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Genetics, Medical; Humans; Hydantoins; Hypoglycemia; Infant; Intellectual Disability; Seizures; Spasms, Infantile; Television; Tuberous Sclerosis

1964
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
    Epilepsia, 1964, Volume: 5

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology

1964
[CONTRIBUTION TO THE STUDY OF EPILEPSY AND SIMILAR SYNDROMES IN CHILDHOOD].
    Rivista di clinica pediatrica, 1963, Volume: 72

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Autonomic Nervous System Diseases; Barbiturates; Cerebral Palsy; Child; Epilepsy; Humans; Hydantoins; Oxyphenbutazone; Seizures; Syndrome

1963
[EFFECT AND INDICATION OF A NEW ANTIEPILEPTIC DRUG].
    Deutsche medizinische Wochenschrift (1946), 1964, Sep-04, Volume: 89

    Topics: Anticonvulsants; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Hydantoins; Phenobarbital; Seizures; Sympathomimetics; Temporal Lobe; Toxicology

1964
[THE PROSTRATION SYNDROME. SERIOUS DANGER OF DRUG THERAPY IN EPILEPSY].
    Deutsche medizinische Wochenschrift (1946), 1964, Sep-04, Volume: 89

    Topics: Adolescent; Anticonvulsants; Chlorpromazine; Down Syndrome; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Hydantoins; Phenobarbital; Primidone; Seizures; Toxicology

1964
[GABOB IN PEDIATRICS. CLINICAL AND ELECTROENCEPHALOGRAPHIC STUDY OF 28 CASES].
    Minerva pediatrica, 1964, Jun-30, Volume: 16

    Topics: Adolescent; Aminobutyrates; Barbiturates; Brain Injuries; Cerebral Palsy; Child; Electroencephalography; Epilepsy; Epilepsy, Post-Traumatic; gamma-Aminobutyric Acid; Humans; Hydantoins; Infant; Intellectual Disability; Movement Disorders; Pediatrics; Seizures

1964
[DRUG THERAPY OF EPILEPSY. INTRODUCTION].
    Nordisk medicin, 1965, Mar-11, Volume: 73

    Topics: Acetazolamide; Barbiturates; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Seizures; Temporal Lobe; Valerian

1965
[ANTIEPILEPTIC ACTIVITIES OF A NEW COMPOUND, ETHOXYCARBODIPHENYLHYDANTOIN].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Animals; Anticonvulsants; Hydantoins; Mice; Pentylenetetrazole; Pharmacology; Rats; Research; Seizures

1964
[TREATMENT OF EPILEPSY WITH 3-ETHOXYCARBO-5,5-DIPHENYLHYDANTOIN (P-6127), A NEW ANTICONVULSANT].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Anticonvulsants; Ataxia; Blood Chemical Analysis; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Hyperplasia; Myoclonus; Nystagmus, Pathologic; Phenytoin; Seizures; Toxicology

1964
[Effects of antiepileptic drugs on the propagation of convulsive activity in brain-isolated rabbits].
    Bollettino della Societa italiana di biologia sperimentale, 1954, Volume: 30, Issue:6

    Topics: Animals; Anticonvulsants; Brain; Humans; Hydantoins; Rabbits; Reproduction; Seizures

1954
Effects of diphenylhydantoin (dilantin) on adrenal cortical function; a study in nonepileptic human subjects.
    A.M.A. archives of neurology and psychiatry, 1955, Volume: 74, Issue:1

    Topics: Adrenal Cortex; Humans; Hydantoins; Phenytoin; Seizures

1955
A critical evaluation of therapy of febrile seizures.
    The Journal of pediatrics, 1960, Volume: 56

    Topics: Child; Fever; Humans; Hydantoins; Infant; Phenobarbital; Seizures; Seizures, Febrile

1960
Effect of lidocaine and procaine on the electroshock seizure threshold, with a comparison of the effects of phenytoin and phenobarbital.
    Acta psychiatrica Scandinavica. Supplementum, 1960, Volume: 35, Issue:145

    Topics: Convulsive Therapy; Electroconvulsive Therapy; Electroshock; Humans; Hydantoins; Lidocaine; Phenobarbital; Phenytoin; Procaine; Seizures

1960
Anticonvulsant effect of nialamide and diphenylhydantoin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1961, Volume: 108

    Topics: Anticonvulsants; Hydantoins; Nialamide; Phenytoin; Psychopharmacology; Seizures

1961
[Differentiation of methylphenylethylhydantoin's (mesantoin's) mode of action in epileptic and in tetanic convulsions].
    Wiener klinische Wochenschrift, 1950, Oct-20, Volume: 62, Issue:42

    Topics: Epilepsy; Humans; Hydantoins; Mephenytoin; Seizures; Tetany

1950
Comparative results in seizure control using phenobarbital, dilantin, and mesantoin.
    The American journal of psychiatry, 1950, Volume: 107, Issue:6

    Topics: Barbital; Epilepsy; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Seizures

1950
Drug-modified electric shock therapy; clinical response to partial seizures facilitated by the anticonvulsant drugs, diphenylhydantoin and mephenesin, alone and in combination.
    The Psychiatric quarterly, 1951, Volume: 25, Issue:4

    Topics: Anticonvulsants; Convulsive Therapy; Electroconvulsive Therapy; Humans; Hydantoins; Mephenesin; Phenytoin; Seizures

1951
Mesantoin in the treatment of convulsive disorders.
    Diseases of the nervous system, 1951, Volume: 12, Issue:9

    Topics: Epilepsy; Hydantoins; Mephenytoin; Seizures

1951
A comparative study of the anticonvulsant effect of the N-substituted 5,5-diallylbarbiturates and 5,5-diphenylhydantoins.
    Acta physiologica Scandinavica, 1951, Volume: 24, Issue:2-3

    Topics: Anticonvulsants; Barbiturates; Humans; Hydantoins; Phenytoin; Pilocarpine; Seizures

1951
Effects of chronic administration of anticonvulsant drugs, alone and on combination with desoxycorticosterone, on electroshock seizure threshold and tissue electrolytes.
    The Journal of pharmacology and experimental therapeutics, 1952, Volume: 105, Issue:1

    Topics: Anticonvulsants; Barbiturates; Brain; Desoxycorticosterone; Electrolytes; Electroshock; Hydantoins; Pharmaceutical Preparations; Seizures

1952
Anticonvulsant activity of phenylmethylenehydantoins: a structure-activity relationship study.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Animals; Anticonvulsants; Electroshock; Hydantoins; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Multivariate Analysis; Quantitative Structure-Activity Relationship; Seizures

2004
Ketogenic and other derivatives of hydantoin as anticonvulsants; further results.
    Stanford medical bulletin, 1949, Volume: 7, Issue:4

    Topics: Anticonvulsants; Humans; Hydantoins; Imidazoles; Ketone Bodies; Seizures

1949
Anticonvulsant activities of certain thiazolidones and hydantoins as determined by electric shock procedures in cats, rats and mice.
    Archives of neurology and psychiatry, 1949, Volume: 62, Issue:6

    Topics: Animals; Anticonvulsants; Cats; Convulsive Therapy; Electroshock; Hydantoins; Mice; Rats; Seizures; Thiazoles

1949
Methyl-phenyl-ethyl hydantoin in the treatment of convulsive disorders.
    Bulletin of the Los Angeles Neurological Society, 1949, Volume: 14, Issue:4

    Topics: Anticonvulsants; Hydantoins; Imidazoles; Seizures

1949
Accidental acute dilantin poisoning; report of a case with complete recovery in a nonepileptic child.
    The Journal of pediatrics, 1950, Volume: 36, Issue:5

    Topics: Cardiovascular Agents; Hydantoins; Phenytoin; Seizures

1950
A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile.
    Neuropharmacology, 2007, Volume: 52, Issue:3

    Topics: Animals; Anticonvulsants; Behavior, Animal; Cell Line, Transformed; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation; Electric Stimulation; Humans; Hydantoins; Ion Channel Gating; Male; Membrane Potentials; Mice; Models, Molecular; Patch-Clamp Techniques; Phenytoin; Seizures; Sodium Channels; Transfection

2007
Synthesis and potential anticonvulsant activity of new N-3-substituted 5,5-cyclopropanespirohydantoins.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:1

    Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Hydantoins; Mice; Rats; Seizures; Spiro Compounds; Structure-Activity Relationship

2009
Ethotoin use in pediatric seizure patients.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:12

    Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Hydantoins; Seizures

1981
Ethotoin in seizures of childhood and adolescence.
    Neurology, 1984, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Child; Female; Humans; Hydantoins; Kinetics; Male; Seizures

1984
[Synthesis of various 5,5-substituted derivatives of 3-dialkylamino-alkylohydantoin with potential pharmacological activity].
    Acta poloniae pharmaceutica, 1984, Volume: 41, Issue:3

    Topics: Anticonvulsants; Chemical Phenomena; Chemistry; Humans; Hydantoins; Seizures

1984
[Synthesis of benzylidene derivatives of 3-o, 3-m and 3-p-chlorophenylhydantoin and the study of their anticonvulsant action].
    Acta poloniae pharmaceutica, 1984, Volume: 41, Issue:4

    Topics: Animals; Benzylidene Compounds; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Hydantoins; Male; Mice; Phenytoin; Seizures

1984
A spirohydantoin derivative of dimethoxytetrahydronaphthalene: an experimental anticonvulsant.
    Neurochemical research, 1984, Volume: 9, Issue:4

    Topics: Animals; Anticonvulsants; Electroshock; Exploratory Behavior; Hydantoins; Male; Mice; Motor Activity; Pentylenetetrazole; Seizures

1984
Naloxone-6-spirohydantoin: a new non-toxic compound with anticonvulsive properties.
    Neuropharmacology, 1983, Volume: 22, Issue:9

    Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Hydantoins; Male; Mice; Naloxone; Pentylenetetrazole; Seizures

1983
[Preliminary comparative pharmacological studies of 3-aryl and 3-alkyl-5-benzylidene derivatives of hydantoin, 2-thiohydantoin and 2-selenohydantoin].
    Acta poloniae pharmaceutica, 1983, Volume: 40, Issue:4

    Topics: Animals; Benzylidene Compounds; Hydantoins; Hyperglycemia; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Seizures; Selenium; Thiohydantoins

1983
Potential anticonvulsants. 1. 5-Benzylhydantoins.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:4

    Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Hydantoins; Male; Mice; Rats; Seizures; Structure-Activity Relationship

1981
Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:10

    Topics: Amino Acids; Animals; Anticonvulsants; Catalysis; Crystallography, X-Ray; Cyclization; Drug Design; Hydantoins; Lactams; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Neuroblastoma; Pentylenetetrazole; Phenobarbital; Phenytoin; Proline; Rats; Seizures; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured

2001
Aminoderivatives of cycloalkanespirohydantoins: synthesis and biological activity.
    Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Central Nervous System; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Hydantoins; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Muscle Contraction; Seizures; Spectrophotometry, Infrared; Structure-Activity Relationship

2002
[Nor-tropan hydantoins n-substituted: action on smooth muscle, and its antiarrhythmic and anticonvulsant effects (author's transl)].
    Archivos de farmacologia y toxicologia, 1977, Volume: 3, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Drug Evaluation; Hydantoins; Intestines; Isoproterenol; Mice; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Nortropanes; Rabbits; Seizures; Tachycardia

1977
Anticonvulsants. 5. Derivatives of 5-ethyl-5-phenylhydantoin and 5,5-diphenylhydantoin.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:4

    Topics: Animals; Anticonvulsants; Depression, Chemical; Electroshock; Hydantoins; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Reflex; Seizures; Sleep

1975
Paradoxical intoxication--a complication of anticonvulsant administration.
    Epilepsia, 1975, Volume: 16, Issue:5

    Topics: Carbamazepine; Drug Therapy, Combination; Humans; Hydantoins; Mephenytoin; Phenytoin; Seizures

1975
Antiepileptic medications.
    Compendium (Newtown, Pa.). Supplement, 1990, Mar-06, Issue:14

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Dental Care for Disabled; Epilepsy; Humans; Hydantoins; Seizures; Valproic Acid

1990
Prevention of hyperthermia-induced seizures in immature rats by a hydantoin derivative of naloxone.
    Life sciences, 1989, Volume: 45, Issue:10

    Topics: Animals; Body Temperature; Environment, Controlled; Fever; Hydantoins; Hyperthermia, Induced; Naloxone; Rats; Rats, Inbred Strains; Seizures; Sodium Chloride

1989
Anticonvulsant properties of spirohydantoins derived from optical isomers of camphor.
    Neurochemical research, 1986, Volume: 11, Issue:12

    Topics: Animals; Anticonvulsants; Camphor; Double-Blind Method; Hydantoins; Male; Mice; Pentylenetetrazole; Seizures; Stereoisomerism

1986
[The treatment of epiletic seizures in childhood].
    Munchener medizinische Wochenschrift (1950), 1968, May-24, Volume: 110, Issue:21

    Topics: Adrenocorticotropic Hormone; Ambulatory Care; Anticonvulsants; Barbiturates; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Hydantoins; Male; Oxyphenbutazone; Phenobarbital; Prednisone; Pyrimidines; Pyrrolidinones; Seizures; Sex Factors

1968
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
    European journal of pharmacology, 1967, Volume: 1, Issue:5

    Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione

1967
Absence status. A reappraisal following review of thirty-eight patients.
    Epilepsia, 1972, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Barbiturates; Carbon Dioxide; Child; Consciousness; Conversion Disorder; Diagnosis, Differential; Electroencephalography; Epilepsy; Female; Humans; Hydantoins; Male; Seizures; Social Behavior Disorders; Succinimides; Temporal Lobe; Trimethadione

1972
[Leukaemia following hydantoin treatment].
    Munchener medizinische Wochenschrift (1950), 1973, Jul-13, Volume: 115, Issue:28

    Topics: Aged; Female; Humans; Hydantoins; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenytoin; Seizures

1973
Dental care of epileptics.
    Epilepsia, 1972, Volume: 13, Issue:1

    Topics: Anesthesia, Dental; Dental Caries; Dentistry; Dentures; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; Lidocaine; Malocclusion; Periodontal Diseases; Seizures; Socioeconomic Factors

1972
[New methods of seizure treatment in epilepsy].
    Munchener medizinische Wochenschrift (1950), 1965, Nov-05, Volume: 107, Issue:45

    Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Hydantoins; Myoclonus; Oxyphenbutazone; Phenobarbital; Seizures

1965
Further observations on the role of -aminobutyric acid in insulin-induced hypoglycaemic convulsions.
    European journal of pharmacology, 1972, Volume: 17, Issue:1

    Topics: Acetates; Amino Acids; Aminobutyrates; Animals; Anticonvulsants; Blood Glucose; Brain; Brain Chemistry; Caffeine; Glycolates; Hydantoins; Hydroxylamines; Hypoglycemia; Insulin; Male; Mice; Pyridoxine; Seizures

1972
[Febrile convulsions in children].
    Archives francaises de pediatrie, 1972, Volume: 29, Issue:1

    Topics: Barbiturates; Brain Damage, Chronic; Child; Child, Preschool; Electroencephalography; Epilepsy; Fever; Humans; Hydantoins; Seizures

1972
A new metabolite of 5,5-diphenylhydantoin (Dilantin).
    Biochemical and biophysical research communications, 1970, Feb-06, Volume: 38, Issue:3

    Topics: Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Electroshock; Hot Temperature; Hydantoins; Hydrogen-Ion Concentration; Infrared Rays; Light; Mice; Models, Structural; Phenytoin; Rotation; Seizures; Spectrophotometry; Ultraviolet Rays

1970
Pharmacologic interactions of albutoin with other anticonvulsant drugs.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:2

    Topics: Animals; Anticonvulsants; Drug Synergism; Electroshock; Hydantoins; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione

1970
[Introduction of mass psychology in animals to pharmacology. 7. Mutural relation in convulsion of El-mice and drugs acting on the central nervous system].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Volume: 66, Issue:6

    Topics: Aminobutyrates; Animals; Anticonvulsants; Behavior, Animal; Hydantoins; Imidazoles; Mice; Phenobarbital; Picrotoxin; Psychology; Seizures

1970
Effect of drugs on interictal spikes and after-discharges in experimental epilepsy.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:2

    Topics: Animals; Anticonvulsants; Cats; Electroencephalography; Glutethimide; Hippocampus; Hydantoins; Meprobamate; Phenobarbital; Receptors, Drug; Seizures; Trimethadione; Tungsten

1971
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
    Archives of dermatology, 1968, Volume: 97, Issue:3

    Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female; Humans; Hydantoins; Hydrochlorothiazide; Lymphoma; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures

1968
The anticonvulsant activity of 3-ethoxycarbonyl-5,5-diphenylhydantoin (P-6127) in animals.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 156, Issue:2

    Topics: Animals; Cats; Electroencephalography; Hydantoins; Mice; Phenytoin; Rats; Seizures

1965