loperamide has been researched along with Seizures in 3 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Constipation is a common gastrointestinal disorder characterized by symptoms such as straining, hard stool, and infrequent defecation." | 5.42 | Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice. ( Inaloo, S; Moezi, L; Pirsalami, F, 2015) |
| " serraefolia significantly delayed the onset of tonic seizures induced by strychnine and pentylenetetrazol; besides, it diminished the death rate and number of animals that exhibited convulsions." | 3.69 | Evaluation of the calcium-antagonist, antidiarrhoeic and central nervous system activities of Baccharis serraefolia. ( Aguilar-Santamaría, L; Tortoriello, J, 1996) |
| "Constipation is a common gastrointestinal disorder characterized by symptoms such as straining, hard stool, and infrequent defecation." | 1.42 | Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice. ( Inaloo, S; Moezi, L; Pirsalami, F, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moezi, L | 1 |
| Pirsalami, F | 1 |
| Inaloo, S | 1 |
| Weaver, LT | 1 |
| Richmond, SW | 1 |
| Nelson, R | 1 |
| Tortoriello, J | 1 |
| Aguilar-Santamaría, L | 1 |
3 other studies available for loperamide and Seizures
| Article | Year |
|---|---|
Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice.
Topics: Animals; Antidiarrheals; Constipation; Convulsants; Disease Models, Animal; Drug Interactions; Gastr | 2015 |
Loperamide toxicity in severe protracted diarrhoea.
Topics: Diarrhea, Infantile; Humans; Infant; Loperamide; Male; Piperidines; Seizures | 1983 |
Evaluation of the calcium-antagonist, antidiarrhoeic and central nervous system activities of Baccharis serraefolia.
Topics: Administration, Oral; Analysis of Variance; Animals; Antidiarrheals; Calcium; Convulsants; Dose-Resp | 1996 |