selenic acid has been researched along with Seizures in 3 studies
Selenic Acid: A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vitro, sodium selenate reduced tau phosphorylation in human neuroblastoma cells and reversed the increase in tau phosphorylation induced by the PP2A inhibitor, okadaic acid." | 3.78 | Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models. ( Chen, T; Corcoran, NM; Grundy, R; Hovens, CM; Jones, NC; Nguyen, T; O'Brien, TJ; Velakoulis, D, 2012) |
| "Despite many antiseizure medications (ASMs) being available, up to one-third of patients do not achieve seizure control." | 3.30 | Phase II randomised placebo-controlled trial of sodium selenate as a disease-modifying treatment in chronic drug-resistant temporal lobe epilepsy: the SeLECT study protocol. ( Carney, P; Casillas-Espinosa, P; Churilov, L; Gillinder, L; Hovens, CM; Johns, H; Kwan, P; Lawn, N; MacPhail, S; Malpas, C; Nicolo, JP; O'Brien, TJ; Perucca, P; Reutens, D; Shultz, SR; Tailby, C; Velakoulis, D; Vivash, L; Wijayath, M, 2023) |
| "Although drugs are available to control epileptic seizures, these only provide symptomatic relief." | 1.91 | Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy. ( Anderson, A; Barlow, CK; Brady, RD; Braine, EL; Casillas-Espinosa, PM; Harutyunyan, A; Huang, C; Jones, NC; Lee, J; Li, C; Mychasiuk, R; O'Brien, TJ; Schittenhelm, RB; Shah, AD; Shultz, SR; Sun, M, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Casillas-Espinosa, PM | 1 |
| Anderson, A | 1 |
| Harutyunyan, A | 1 |
| Li, C | 1 |
| Lee, J | 1 |
| Braine, EL | 1 |
| Brady, RD | 1 |
| Sun, M | 1 |
| Huang, C | 1 |
| Barlow, CK | 1 |
| Shah, AD | 1 |
| Schittenhelm, RB | 1 |
| Mychasiuk, R | 1 |
| Jones, NC | 2 |
| Shultz, SR | 2 |
| O'Brien, TJ | 3 |
| Vivash, L | 1 |
| Johns, H | 1 |
| Churilov, L | 1 |
| MacPhail, S | 1 |
| Casillas-Espinosa, P | 1 |
| Malpas, C | 1 |
| Tailby, C | 1 |
| Wijayath, M | 1 |
| Reutens, D | 1 |
| Gillinder, L | 1 |
| Perucca, P | 1 |
| Carney, P | 1 |
| Nicolo, JP | 1 |
| Lawn, N | 1 |
| Kwan, P | 1 |
| Velakoulis, D | 2 |
| Hovens, CM | 2 |
| Nguyen, T | 1 |
| Corcoran, NM | 1 |
| Chen, T | 1 |
| Grundy, R | 1 |
1 trial available for selenic acid and Seizures
| Article | Year |
|---|---|
Phase II randomised placebo-controlled trial of sodium selenate as a disease-modifying treatment in chronic drug-resistant temporal lobe epilepsy: the SeLECT study protocol.
Topics: Adult; Animals; Clinical Trials, Phase II as Topic; Drug Resistant Epilepsy; Epilepsy, Temporal Lobe | 2023 |
2 other studies available for selenic acid and Seizures
| Article | Year |
|---|---|
Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy.
Topics: Animals; Drug Resistant Epilepsy; Epilepsy; Epilepsy, Temporal Lobe; Rats; Rats, Wistar; Seizures; S | 2023 |
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.
Topics: Amygdala; Analysis of Variance; Animals; Antioxidants; Cell Line, Tumor; Convulsants; Disease Models | 2012 |