aminolevulinic acid has been researched along with Seizures in 10 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-aminolevulinic acid (5-ALA) has been increasingly used in recent years to identify anaplastic foci in primarily suspected low-grade gliomas (LGGs)." | 7.96 | Influence of Corticosteroids and Antiepileptic Drugs on Visible 5-Aminolevulinic Acid Fluorescence in a Series of Initially Suspected Low-Grade Gliomas Including World Health Organization Grade II, III, and IV Gliomas. ( Berger, MS; Borkovec, M; Furtner, J; Hervey-Jumper, S; Hosmann, A; Kiesel, B; Mercea, PA; Mischkulnig, M; Rössler, K; Rötzer, T; Wadiura, LI; Widhalm, G, 2020) |
| "5-aminolevulinic acid (5-ALA) has been increasingly used in recent years to identify anaplastic foci in primarily suspected low-grade gliomas (LGGs)." | 5.56 | Influence of Corticosteroids and Antiepileptic Drugs on Visible 5-Aminolevulinic Acid Fluorescence in a Series of Initially Suspected Low-Grade Gliomas Including World Health Organization Grade II, III, and IV Gliomas. ( Berger, MS; Borkovec, M; Furtner, J; Hervey-Jumper, S; Hosmann, A; Kiesel, B; Mercea, PA; Mischkulnig, M; Rössler, K; Rötzer, T; Wadiura, LI; Widhalm, G, 2020) |
| "Clonazepam was ineffective in treating the seizures and, in high doses, seemed to exacerbate the porphyria." | 5.26 | Seizure management in acute hepatic porphyria: risks of valproate and clonazepam. ( Bonkowsky, HL; Emery, S; Sinclair, JF; Sinclair, PR, 1980) |
| "We studied one patient with major motor seizures and acute intermittent porphyria." | 5.26 | Seizure management in acute hepatic porphyria: risks of valproate and clonazepam. ( Bonkowsky, HL; Emery, S; Sinclair, JF; Sinclair, PR, 1980) |
| "5-aminolevulinic acid (5-ALA) has been increasingly used in recent years to identify anaplastic foci in primarily suspected low-grade gliomas (LGGs)." | 3.96 | Influence of Corticosteroids and Antiepileptic Drugs on Visible 5-Aminolevulinic Acid Fluorescence in a Series of Initially Suspected Low-Grade Gliomas Including World Health Organization Grade II, III, and IV Gliomas. ( Berger, MS; Borkovec, M; Furtner, J; Hervey-Jumper, S; Hosmann, A; Kiesel, B; Mercea, PA; Mischkulnig, M; Rössler, K; Rötzer, T; Wadiura, LI; Widhalm, G, 2020) |
| " Aminolaevulinic acid was administered by intraperitoneal or subcutaneous injection to mice in doses up to 1000 mg/kg and effects on nociception (hot-plate and abdominal constriction tests), CNS excitability (pentobarbitone sleep-time and pentylenetetrazole-induced seizures), motor co-ordination and grip (rotating rod test) were studied." | 3.67 | Neuropharmacology of delta-aminolaevulinic acid--I. Effect of acute administration in rodents. ( Edwards, SR; Reynoldson, JA; Shanley, BC, 1984) |
| "Headache is common in PRES, though headache associated with PRES was not identified as a separate entity in the 2018 International Classification of Headache Disorders." | 2.72 | Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021) |
| "Associations with PRES include renal failure, preeclampsia and eclampsia, autoimmune conditions, and immunosuppression." | 2.72 | Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021) |
| "5-aminolevulinic acid (5-ALA) has been increasingly used in recent years to identify anaplastic foci in primarily suspected low-grade gliomas (LGGs)." | 1.56 | Influence of Corticosteroids and Antiepileptic Drugs on Visible 5-Aminolevulinic Acid Fluorescence in a Series of Initially Suspected Low-Grade Gliomas Including World Health Organization Grade II, III, and IV Gliomas. ( Berger, MS; Borkovec, M; Furtner, J; Hervey-Jumper, S; Hosmann, A; Kiesel, B; Mercea, PA; Mischkulnig, M; Rössler, K; Rötzer, T; Wadiura, LI; Widhalm, G, 2020) |
| "ALA-induced convulsions were not prevented by ascorbic acid, but were partially prevented by DMSO and completely prevented by ebselen." | 1.32 | Dimethyl sulfoxide and ebselen prevent convulsions induced by 5-aminolevulinic acid. ( Agostini, AN; Augusti, PR; Emanuelli, T; Mello, CF; Morimoto, A; Prauchner, CA; Unfer, TC; Zeni, G, 2004) |
| "Seizures were induced in a variety of inbred strains of mice including C57BL, C3H, DBA mice and in a heterogeneous stock of mice." | 1.27 | Genetic differences in the effects of delta-aminolevulinic acid on seizure latency in mice. ( Marley, RJ; Wehner, JM, 1986) |
| "injections also delayed clonic seizures induced by flurothyl, and increased the latency to tonic seizures induced by 3-mercaptopropionic acid." | 1.27 | Genetic differences in the effects of delta-aminolevulinic acid on seizure latency in mice. ( Marley, RJ; Wehner, JM, 1986) |
| "Clonazepam was ineffective in treating the seizures and, in high doses, seemed to exacerbate the porphyria." | 1.26 | Seizure management in acute hepatic porphyria: risks of valproate and clonazepam. ( Bonkowsky, HL; Emery, S; Sinclair, JF; Sinclair, PR, 1980) |
| "We studied one patient with major motor seizures and acute intermittent porphyria." | 1.26 | Seizure management in acute hepatic porphyria: risks of valproate and clonazepam. ( Bonkowsky, HL; Emery, S; Sinclair, JF; Sinclair, PR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wadiura, LI | 1 |
| Mischkulnig, M | 1 |
| Hosmann, A | 1 |
| Borkovec, M | 1 |
| Kiesel, B | 1 |
| Rötzer, T | 1 |
| Mercea, PA | 1 |
| Furtner, J | 1 |
| Hervey-Jumper, S | 1 |
| Rössler, K | 1 |
| Berger, MS | 1 |
| Widhalm, G | 1 |
| Gewirtz, AN | 1 |
| Gao, V | 1 |
| Parauda, SC | 1 |
| Robbins, MS | 1 |
| Prauchner, CA | 1 |
| Agostini, AN | 1 |
| Morimoto, A | 1 |
| Augusti, PR | 1 |
| Unfer, TC | 1 |
| Zeni, G | 1 |
| Mello, CF | 1 |
| Emanuelli, T | 1 |
| Silbergeld, EK | 1 |
| Edwards, SR | 1 |
| Shanley, BC | 1 |
| Reynoldson, JA | 1 |
| Bonkowsky, HL | 2 |
| Schady, W | 1 |
| Sinclair, PR | 1 |
| Emery, S | 1 |
| Sinclair, JF | 1 |
| O'Connor, LJ | 1 |
| Pierach, CA | 1 |
| Edwards, PS | 1 |
| Wehner, JM | 1 |
| Marley, RJ | 1 |
2 reviews available for aminolevulinic acid and Seizures
| Article | Year |
|---|---|
Posterior Reversible Encephalopathy Syndrome.
Topics: Acute Chest Syndrome; Aminolevulinic Acid; Anemia, Sickle Cell; Autoimmune Diseases; Blood-Brain Bar | 2021 |
Neurologic manifestations of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology; | 1982 |
8 other studies available for aminolevulinic acid and Seizures
| Article | Year |
|---|---|
Influence of Corticosteroids and Antiepileptic Drugs on Visible 5-Aminolevulinic Acid Fluorescence in a Series of Initially Suspected Low-Grade Gliomas Including World Health Organization Grade II, III, and IV Gliomas.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aminolevulinic Acid; Anticonvulsants; Brain Neoplasms; Female; | 2020 |
Dimethyl sulfoxide and ebselen prevent convulsions induced by 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Azoles; Dimethyl Sulfoxide; Isoindoles; Male; Organoselenium Compounds | 2004 |
Indirectly acting neurotoxins.
Topics: Aminolevulinic Acid; Animals; Brain; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Lead Pois | 1983 |
Neuropharmacology of delta-aminolaevulinic acid--I. Effect of acute administration in rodents.
Topics: Aminolevulinic Acid; Analgesia; Animals; Blood Pressure; Heart Rate; Levulinic Acids; Mice; Motor Ac | 1984 |
Seizure management in acute hepatic porphyria: risks of valproate and clonazepam.
Topics: 5-Aminolevulinate Synthetase; Adult; Aminolevulinic Acid; Animals; Benzodiazepinones; Chick Embryo; | 1980 |
Acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Male; Porphobilinogen; Porphyrias; Seizur | 1981 |
Neurotoxicity of delta-aminolevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Animals; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; | 1978 |
Genetic differences in the effects of delta-aminolevulinic acid on seizure latency in mice.
Topics: Aminolevulinic Acid; Animals; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Levulinic Acids; | 1986 |