3-hydroxykynurenine has been researched along with Seizures in 5 studies
3-hydroxykynurenine: RN given refers to cpd without isomeric designation
3-hydroxykynurenine : A hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3.
hydroxykynurenine : A hydroxy-amino acid that is kynurenine substituted by a single hydroxy group at unspecified position. A "closed" class.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These changes preceded the onset of EEG seizures, which had a mean onset of 108 h after inoculation." | 1.35 | Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice. ( Bertram, EH; Guidetti, P; Lehrmann, E; Löve, A; Schwarcz, R; Williamson, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lehrmann, E | 1 |
| Guidetti, P | 1 |
| Löve, A | 1 |
| Williamson, J | 1 |
| Bertram, EH | 1 |
| Schwarcz, R | 1 |
| McKiernan, J | 2 |
| Mellor, DH | 1 |
| Court, S | 2 |
| Mellor, D | 1 |
| Edson, J | 1 |
| Lacey, K | 1 |
| Eastman, CL | 1 |
| Guilarte, TR | 2 |
| Block, LD | 1 |
| Wagner, HN | 1 |
1 review available for 3-hydroxykynurenine and Seizures
| Article | Year |
|---|---|
Cytotoxicity of 3-hydroxykynurenine: implications for CNS damage in neonatal vitamin B-6 deficiency.
Topics: Animals; Animals, Newborn; Antioxidants; Brain; Brain Chemistry; Cell Death; Hybrid Cells; Hydrolase | 1991 |
1 trial available for 3-hydroxykynurenine and Seizures
| Article | Year |
|---|---|
A controlled trial of pyridoxine supplementation in children with febrile convulsions.
Topics: 3-Hydroxyanthranilic Acid; Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Kynur | 1981 |
3 other studies available for 3-hydroxykynurenine and Seizures
| Article | Year |
|---|---|
Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice.
Topics: Animals; Animals, Newborn; Astrocytes; Behavior, Animal; Cell Count; Coloring Agents; Cricetinae; Di | 2008 |
Hydroxykynurenine/hydroxyanthranilic acid ratios and febrile convulsions.
Topics: 3-Hydroxyanthranilic Acid; Child, Preschool; Humans; Infant; Kynurenine; ortho-Aminobenzoates; Seizu | 1980 |
The putative endogenous convulsant 3-hydroxykynurenine decreases benzodiazepine receptor binding affinity: implications to seizures associated with neonatal vitamin B-6 deficiency.
Topics: Animals; Brain; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Kynurenine; Male; Rat | 1988 |