Page last updated: 2024-08-26

cilastatin and Seizures

cilastatin has been researched along with Seizures in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (26.67)	18.7374
1990's	11 (36.67)	18.2507
2000's	8 (26.67)	29.6817
2010's	3 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benjamin, DK; Capparelli, EV; Clark, RH; Cohen-Wolkowiez, M; Herring, AH; Hornik, CP; Kearns, GL; Smith, PB; van den Anker, J	1
Cannon, JP; Clark, NM; Grim, SA; Lee, TA; Setlak, P	1
Chen, K; Shi, Z; Wang, Q; Wu, Y	1
Galante, D	1
Arnold, HM; Augustin, KM; Casabar, E; Dubberke, ER; Hladnik, LM; McKinnon, PS; Reichley, RM; Ritchie, DJ; Westervelt, P	1
Kurata, Y; Kurosawa, T; Nawa, T; Shibasaki, S; Suzuki, H; Yagi, Y	1
Fukuda, H; Kawamura, Y	1
Lovic, OS; Susic, V; Zivanovic, D	1
Stanojlovic, O; Stojanovic, J; Susic, V; Zivanovic, D	2
Day, IP; Goudie, J; Nishiki, K; Williams, PD	1
Caldwell, JW; Fink, MP; Heard, SO; Johnson, RH; Leeper, KV; Niederman, MS; Schentag, JJ; Siami, GA; Snydman, DR; Wunderink, RG	1
Burke, JP; Classen, DC; Evans, RS; Pestotnik, SL; Stevens, LE	1
Kania, D; Lane, M; Rapp, RP	1
Guglielmo, BJ; Jacobs, RA	1
Norrby, SR	2
Campise, M	1
Hill, EM; McCarthy, ID; Mostow, SR; Newcomb, HW	1
Ballow, CH; Leo, RJ	1
Inderlied, CB; Kim, KS; Mason, WH; Ross, LA; Wong, VK; Wright, HT	1
Brown, RB; Morris, AB; Sands, M	1
Eguchi, T; Fujishita, M; Kataoka, R; Kotani, S; Miyagi, T; Miyoshi, I; Taguchi, H; Takeuchi, T	1
Giles, RE; Patel, JB	1
Haruta, T; Kobayashi, Y; Kubo, K; Kuroki, S; Okura, KE; Yamamoto, H; Yamaoka, K	1
Schliamser, SE	1
Calandra, G; Carrigan, J; Guess, H; Lydick, E; Weiss, L	1
Bennett, DB; Comereski, CR; Williams, PD	1
Ahonkhai, VI; Aziz, MA; Brown, KR; Calandra, GB; Grad, LC; Wang, C	1
Alexander, JW; Fant, WK; Rivera, JO; Solomkin, JS	1

Reviews

3 review(s) available for cilastatin and Seizures

Article	Year
The risk of seizures among the carbapenems: a meta-analysis. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Doripenem; Drug Combinations; Ertapenem; Humans; Imipenem; Meropenem; Risk; Seizures; Thienamycins	2014
Neurotoxicity of carbapenem antibacterials. Drug safety, 1996, Volume: 15, Issue:2 Topics: Animals; Carbapenems; Child; Cilastatin; Humans; Imipenem; Meropenem; Receptors, GABA; Seizures; Thienamycins	1996
Carbapenems in serious infections: a risk-benefit assessment. Drug safety, 2000, Volume: 22, Issue:3 Topics: Adult; Cephalosporins; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Tolerance; Humans; Imipenem; Meningitis, Bacterial; Meropenem; Risk Assessment; Seizures; Thienamycins	2000

Trials

4 trial(s) available for cilastatin and Seizures

Article	Year
Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double-blind trial comparing intravenous ciprofloxacin with imipenem-cilastatin. The Severe Pneumonia Study Group. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3 Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Double-Blind Method; Drug Combinations; Drug Resistance, Microbial; Female; Hospitalization; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Regression Analysis; Seizures	1994
Imipenem/cilastatin treatment of bacterial meningitis in children. The Pediatric infectious disease journal, 1991, Volume: 10, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Infections; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Infant; Male; Meningitis; Meningitis, Haemophilus; Meningitis, Meningococcal; Retrospective Studies; Seizures	1991
Factors predisposing to seizures in seriously ill infected patients receiving antibiotics: experience with imipenem/cilastatin. The American journal of medicine, 1988, Volume: 84, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Infections; Body Weight; Central Nervous System Diseases; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Cyclopropanes; Drug Combinations; Female; Humans; Imipenem; Kidney Function Tests; Male; Regression Analysis; Retrospective Studies; Risk Factors; Seizures; Thienamycins; Time Factors; United States	1988
Randomized trial of imipenem/cilastatin versus gentamicin and clindamycin in mixed flora infections. The American journal of medicine, 1985, Jun-07, Volume: 78, Issue:6A Topics: Adult; Aged; Bacterial Infections; Cilastatin; Clindamycin; Clinical Trials as Topic; Creatinine; Cyclopropanes; Drug Combinations; Female; Gentamicins; Humans; Imipenem; Male; Middle Aged; Random Allocation; Seizures; Thienamycins	1985

Other Studies

23 other study(ies) available for cilastatin and Seizures

Article	Year
Adverse events associated with meropenem versus imipenem/cilastatin therapy in a large retrospective cohort of hospitalized infants. The Pediatric infectious disease journal, 2013, Volume: 32, Issue:7 Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Humans; Imipenem; Incidence; Infant; Intensive Care, Neonatal; Meropenem; Retrospective Studies; Seizures; Survival Analysis; Thienamycins	2013
A Retrospective Study on the Incidence of Seizures among Neurosurgical Patients Who Treated with Imipenem/Cilastatin or Meropenem. Current pharmaceutical biotechnology, 2014, Volume: 15, Issue:8 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Incidence; Male; Meropenem; Middle Aged; Retrospective Studies; Seizures; Thienamycins; Young Adult	2014
An unusual cause of seizures during subarachnoid anesthesia in a patient undergoing transurethral resection of the prostate: a case report. Minerva anestesiologica, 2009, Volume: 75, Issue:4 Topics: Aged; Anesthesia, Spinal; Anesthetics, Local; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cilastatin; Diagnosis, Differential; Humans; Imipenem; Intraoperative Complications; Male; Preanesthetic Medication; Prostatic Hyperplasia; Seizures; Subarachnoid Space; Transurethral Resection of Prostate	2009
Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in adults with neutropenic fever. Pharmacotherapy, 2009, Volume: 29, Issue:8 Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Dose-Response Relationship, Drug; Drug Combinations; Female; Fever; Hospital Mortality; Humans; Imipenem; Male; Meropenem; Middle Aged; Neutropenia; Retreatment; Seizures; Thienamycins; Time Factors	2009
[Convulsive liability of an oral carbapenem antibiotic, tebipenem pivoxil]. The Japanese journal of antibiotics, 2009, Volume: 62, Issue:3 Topics: Administration, Oral; Animals; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Imipenem; Infusions, Intravenous; Injections, Intraventricular; Male; Mice; Pentylenetetrazole; Rats; Seizures	2009
[Drug interactions between nonsteroidal anti-inflammatory drug and pazufloxacin mesilate, a new quinolone antibacterial agent for intravenous use: convulsions in mice after intravenous or intracerebroventricular administration]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3 Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Alanine; Biphenyl Compounds; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Ciprofloxacin; Convulsants; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Imipenem; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Norfloxacin; Oxazines; Penicillin G; Quinolones; Seizures; Thienamycins	2002
Effects of manipulation of N-methyl-D-aspartate receptors on imipenem/cilastatin-induced seizures in rats. The Indian journal of medical research, 2004, Volume: 119, Issue:2 Topics: Acetamides; Animals; Binding Sites; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Electroencephalography; Imipenem; Male; Pyrrolidinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Valine	2004
Induction of audiogenic seizures in imipenem/cilastatin-treated rats. Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:2 Topics: Animals; Anti-Bacterial Agents; Brain; Cilastatin; Dipeptidases; Drug Therapy, Combination; Electroencephalography; Imipenem; Injections, Intraventricular; Male; Motor Activity; Rats; Rats, Wistar; Seizures; Signal Processing, Computer-Assisted	2004
The effects of phenytoin and phenobarbital on seizures induced by imipenem/cilastatin in rats. Acta neurologica Belgica, 2004, Volume: 104, Issue:1 Topics: Animals; Anticonvulsants; Cilastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Imipenem; Injections, Intraventricular; Male; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Seizures	2004
Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem. Toxicology letters, 1995, Volume: 76, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Cilastatin; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipenem; Injections, Intravenous; Male; Meropenem; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Thienamycins	1995
Prospective surveillance of imipenem/cilastatin use and associated seizures using a hospital information system. The Annals of pharmacotherapy, 1993, Volume: 27, Issue:4 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Algorithms; Child; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Pharmacy Information Systems; Drug Combinations; Female; Hospital Bed Capacity, 500 and over; Hospitals, University; Humans; Imipenem; Incidence; Length of Stay; Male; Middle Aged; Patient Admission; Population Surveillance; Prospective Studies; Seizures; Utah	1993
Seizures related to use of imipenem-cilastatin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Jul-01, Volume: 53, Issue:13 Topics: Adult; Aged; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Male; Middle Aged; Risk Factors; Seizures	1996
Impact of dosage-monitoring system on frequency of seizures associated with imipenem-cilastatin. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Sep-01, Volume: 53, Issue:17 Topics: Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Delivery Systems; Drug Monitoring; Drug Therapy, Combination; Humans; Imipenem; Risk Factors; Seizures	1996
Neurological complication during imipenem/cilastatin therapy in uraemic patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:7 Topics: Aged; Aged, 80 and over; Cilastatin; Confusion; Female; Humans; Imipenem; Male; Middle Aged; Nervous System; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Protease Inhibitors; Seizures; Thienamycins; Tremor; Uremia	1998
Imipenem-cilastatin dosing intervention program by pharmacists. American journal of hospital pharmacy, 1992, Volume: 49, Issue:5 Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Colorado; Drug Combinations; Hospital Bed Capacity, 300 to 499; Humans; Imipenem; Medication Errors; Pharmacists; Pharmacy Service, Hospital; Program Evaluation; Retrospective Studies; Risk Factors; Seizures	1992
Seizure activity associated with imipenem use: clinical case reports and review of the literature. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:4 Topics: Aged; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Male; Middle Aged; Seizures	1991
Seizure propensity with imipenem. Archives of internal medicine, 1990, Volume: 150, Issue:7 Topics: Cilastatin; Cilastatin, Imipenem Drug Combination; Creatinine; Drug Administration Schedule; Drug Combinations; Humans; Imipenem; Seizures	1990
[Seizure and tremor occurring in acute leukemia patients treated with imipenem/cilastatin]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:3 Topics: Acute Disease; Adult; Aged; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Female; Humans; Imipenem; Leukemia; Middle Aged; Seizures; Tremor	1989
Meropenem: evidence of lack of proconvulsive tendency in mice. The Journal of antimicrobial chemotherapy, 1989, Volume: 24 Suppl A Topics: Animals; Carbapenems; Cilastatin; Imipenem; Male; Meropenem; Mice; Seizures; Thienamycins	1989
[Fundamental and clinical evaluation of imipenem/cilastatin sodium in the field of pediatrics]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:7 Topics: Bacterial Infections; Child; Child, Preschool; Cilastatin; Cyclopropanes; Drug Combinations; Drug Eruptions; Female; Humans; Imipenem; Infant; Infusions, Intravenous; Male; Seizures; Thienamycins	1986
Neurotoxicity of beta-lactam antibiotics. Experimental kinetic and neurophysiological studies. Scandinavian journal of infectious diseases. Supplementum, 1988, Volume: 55 Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain; Carbapenems; Cilastatin; Drug Interactions; Electroencephalography; Enterobacteriaceae Infections; Female; Hippocampus; Imipenem; Male; Meningitis; Penicillin G; Rabbits; Rats; Rats, Inbred Strains; Seizures; Thiopental; Tissue Distribution; Uremia	1988
Animal model for evaluating the convulsive liability of beta-lactam antibiotics. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding, Competitive; Cefazolin; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Disease Models, Animal; Drug Combinations; gamma-Aminobutyric Acid; Imipenem; Lactams; Male; Mice; Pentylenetetrazole; Seizures; Thienamycins	1988
Review of adverse experiences and tolerability in the first 2,516 patients treated with imipenem/cilastatin. The American journal of medicine, 1985, Jun-07, Volume: 78, Issue:6A Topics: Adolescent; Adult; Aged; Anaphylaxis; Cilastatin; Cyclopropanes; Digestive System; Drug Combinations; Drug Hypersensitivity; Humans; Imipenem; Liver; Middle Aged; Seizures; Thienamycins	1985