thyroxine has been researched along with Seizures in 39 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seyfried, Glasser, and Yu recently reported that the DBA/2J mouse genotype, which is innately susceptible to audiogenic seizures, has high neonatal levels of thyroxine (T4) and that neonatal injections of T4 induce susceptibility in the C57BL/6J mouse." | 7.66 | Effects of neonatal thyroxine, genotype, and noise on the ear and audiogenic seizures. ( Berard, DR; Chole, RA; Henry, KR; McGinn, MD, 1981) |
| " Propensity score fine-stratification weighted hazard ratios (wHR) with 95% confidence intervals (CIs) were presented to assess the association between maternal levothyroxine use during pregnancy and seizures in children." | 4.31 | Levothyroxine Treatment Among Pregnant Women and Risk of Seizure in Children: A Population-Based Cohort Study. ( Cheung, CL; Cheung, ECL; Ge, GM; Ip, P; Kung, AWC; Leung, WC; Man, KKC; Wong, ICK, 2023) |
| " All women had a blood sample drawn in early pregnancy (median week 9), and the stored sample was used for measurement of free thyroxine and thyrotropin." | 3.88 | Maternal Thyroid Function in Early Pregnancy and Child Neurodevelopmental Disorders: A Danish Nationwide Case-Cohort Study. ( Andersen, S; Andersen, SL; Olsen, J; Vestergaard, P, 2018) |
| " We have previously reported the presence of SBH in a rodent model of low level hypothyroidism induced by maternal exposure to the goitrogen, propylthiouracil (PTU)." | 3.80 | Subcortical band heterotopia in rat offspring following maternal hypothyroxinaemia: structural and functional characteristics. ( Gilbert, ME; Goodman, JH; McCloskey, DP; Ramos, RL, 2014) |
| " He had seizures attacks and apnea from the second week of his life." | 3.78 | Early-onset severe obesity with ACTH deficiency and red hair in a boy: the POMC deficiency. ( Aldemir, O; Ozen, S, 2012) |
| " There were no alterations in body weight or plasma levels of triiodotHyronine (T3) and thyroxine (T4)." | 3.69 | Long-term antiepileptic effects of chronic intake of CNK-602A, a thyrotropin-releasing hormone analogue, on spontaneously epileptic rats. ( Fujita, Y; Ishihara, K; Kimura, K; Momiyama, T; Sasa, M; Serikawa, T; Todo, N, 1996) |
| "The effects of 3,5,3'-triiodothyronine (T3) levels on threshold, latency and duration of pentylenetetrazole-induced seizures were tested in rats treated with thyroxine (300 micrograms/kg." | 3.69 | T3 deficiency prolongs convulsions induced by acute pentylenetetrazole. ( Chambert, G; Pacheco-Rosado, J; Quevedo-Corona, L; Zamudio-Hernández, SR, 1997) |
| "Seyfried, Glasser, and Yu recently reported that the DBA/2J mouse genotype, which is innately susceptible to audiogenic seizures, has high neonatal levels of thyroxine (T4) and that neonatal injections of T4 induce susceptibility in the C57BL/6J mouse." | 3.66 | Effects of neonatal thyroxine, genotype, and noise on the ear and audiogenic seizures. ( Berard, DR; Chole, RA; Henry, KR; McGinn, MD, 1981) |
| "This is an overlooked scleromyxedema case of a 62-year-old female patient from 2-years ago." | 2.66 | Acute Encephalitic Syndrome Induced by Scleromyxedema. ( Anastasiadis, G; Karathanasi, V; Magira, EE; Malouchou, A; Mavropoulou, N; Siempos, II; Sykaras, A; Vourlakou, C, 2020) |
| "The diagnosis of Hashimoto's encephalopathy is made when no other cause is found for an acute encephalopathic illness, in the presence of positive thyroid autoantibodies, and is supported by a response to steroid therapy." | 1.40 | Endocrine encephalopathy. ( Hunt, P; Soule, S; Yong, KW, 2014) |
| "A 16-year-old girl with a history of Graves' disease presented with two episodes of generalised tonic-clonic seizures, necessitating intensive care admission." | 1.38 | Seizures and postictal stupor in a patient with uncontrolled Graves' hyperthyroidism. ( De Leu, N; Poppe, K; Unuane, D; Velkeniers, B, 2012) |
| "Infants and children present with seizures and stroke-like episodes with focal neurologic deficits." | 1.35 | Central hypothyroidism and Sturge-Weber syndrome. ( Bellamkonda, S; Cohen, BA; Comi, AM; Ferenc, LM; Germain-Lee, EL, 2008) |
| "We report a case of a tonic-clonic seizure occurring in a child after ingestion of a maximum of 3." | 1.33 | Seizure in a child after an acute ingestion of levothyroxine. ( Kim, S; Santucci, S; Tsutaoka, BT, 2005) |
| "After 3 years seizure-free period, he had repeated HMS, seven to eight attacks per day, after initiation L-thyroxine treatment." | 1.32 | Thyroxine-induced hypermotor seizure. ( Aydin, A; Baklan, B; Cemeroglu, AP, 2004) |
| "Hashimoto's encephalopathy was diagnosed." | 1.30 | [Variable manifestations of Hashimoto's encephalopathy]. ( Haaxma, R; Schaafsma, A; van Oostrom, JC, 1999) |
| "The seizures were controlled with phenobarbital, but the dog died 2 days after presentation." | 1.27 | Neurologic manifestations of cerebrovascular atherosclerosis associated with primary hypothyroidism in a dog. ( Patterson, JS; Rusley, MS; Zachary, JF, 1985) |
| "Generalized convulsions were particularly common, occuring in five patients." | 1.26 | Unusual presentation of myxoedema coma in the elderly. ( Impallomeni, MG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (48.72) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 5 (12.82) | 29.6817 |
| 2010's | 8 (20.51) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Ge, GM | 1 |
| Man, KKC | 1 |
| Cheung, ECL | 1 |
| Ip, P | 1 |
| Leung, WC | 1 |
| Kung, AWC | 1 |
| Cheung, CL | 1 |
| Wong, ICK | 1 |
| Magira, EE | 1 |
| Malouchou, A | 1 |
| Karathanasi, V | 1 |
| Mavropoulou, N | 1 |
| Siempos, II | 1 |
| Vourlakou, C | 1 |
| Sykaras, A | 1 |
| Anastasiadis, G | 1 |
| Andersen, SL | 1 |
| Andersen, S | 1 |
| Vestergaard, P | 1 |
| Olsen, J | 1 |
| Kutluk, MG | 1 |
| Haznedar, P | 1 |
| Bektas, O | 1 |
| Kadem, N | 1 |
| Tuncer, GO | 1 |
| Albayrak, P | 1 |
| Teber, S | 1 |
| Ozen, S | 1 |
| Aldemir, O | 1 |
| Pocsay, G | 1 |
| Gazdag, A | 1 |
| Engelhardt, J | 1 |
| Szaniszló, I | 1 |
| Szolnoki, Z | 1 |
| Forczek, G | 1 |
| Mikló, L | 1 |
| Gilbert, ME | 1 |
| Ramos, RL | 1 |
| McCloskey, DP | 1 |
| Goodman, JH | 1 |
| Yong, KW | 1 |
| Soule, S | 1 |
| Hunt, P | 1 |
| Comi, AM | 1 |
| Bellamkonda, S | 1 |
| Ferenc, LM | 1 |
| Cohen, BA | 1 |
| Germain-Lee, EL | 1 |
| Banda, P | 1 |
| Allain, TJ | 1 |
| Inoue, H | 1 |
| Ihara, K | 1 |
| Ochiai, M | 1 |
| Takahata, Y | 1 |
| Kohno, H | 1 |
| Hara, T | 1 |
| De Leu, N | 1 |
| Unuane, D | 1 |
| Poppe, K | 1 |
| Velkeniers, B | 1 |
| WOODBURY, DM | 1 |
| HURLEY, RE | 1 |
| LEWIS, NG | 1 |
| MCARTHUR, MW | 1 |
| COPELAND, WW | 1 |
| KIRSCHVINK, JF | 1 |
| GOODMAN, LS | 1 |
| DOMINO, EF | 1 |
| MINZ, B | 1 |
| PASSOUANT-FONTAINE, T | 1 |
| FLANDER, C | 1 |
| PASSOUANT, P | 1 |
| HASSELBLATT, A | 1 |
| BASTIAN, G | 1 |
| PFEIFER, KA | 1 |
| PATAKY, I | 1 |
| SATORY, E | 1 |
| VERTES, P | 1 |
| Rekand, T | 1 |
| Vedeler, C | 1 |
| Gramstad, A | 1 |
| Bindoff, L | 1 |
| Aydin, A | 1 |
| Cemeroglu, AP | 1 |
| Baklan, B | 1 |
| Tsutaoka, BT | 1 |
| Kim, S | 1 |
| Santucci, S | 1 |
| Atterwill, CK | 1 |
| Nutt, DJ | 1 |
| Seyfried, TN | 3 |
| Glaser, GH | 3 |
| Yu, RK | 3 |
| Henry, KR | 1 |
| McGinn, MD | 1 |
| Berard, DR | 1 |
| Chole, RA | 1 |
| Momiyama, T | 1 |
| Ishihara, K | 1 |
| Kimura, K | 1 |
| Todo, N | 1 |
| Fujita, Y | 1 |
| Serikawa, T | 1 |
| Sasa, M | 1 |
| Surks, MI | 1 |
| DeFesi, CR | 1 |
| Pacheco-Rosado, J | 1 |
| Quevedo-Corona, L | 1 |
| Zamudio-Hernández, SR | 1 |
| Chambert, G | 1 |
| van Oostrom, JC | 1 |
| Schaafsma, A | 1 |
| Haaxma, R | 1 |
| Gaskill, CL | 1 |
| Burton, SA | 1 |
| Gelens, HC | 1 |
| Ihle, SL | 1 |
| Miller, JB | 1 |
| Shaw, DH | 1 |
| Brimacombe, MB | 1 |
| Cribb, AE | 1 |
| Alley, MC | 1 |
| Killam, EK | 1 |
| Duvina, PL | 1 |
| Impallomeni, MG | 1 |
| Stjernholm, MR | 1 |
| Alsever, RN | 1 |
| Rudolph, MC | 1 |
| Patterson, JS | 1 |
| Rusley, MS | 1 |
| Zachary, JF | 1 |
| Kulig, K | 1 |
| Golightly, LK | 1 |
| Rumack, BH | 1 |
| Serbanescu, T | 1 |
| Balzamo, E | 1 |
| Pfeifer, AK | 1 |
| Selye, H | 1 |
| Szabo, S | 1 |
| Mécs, I | 1 |
1 review available for thyroxine and Seizures
| Article | Year |
|---|---|
Acute Encephalitic Syndrome Induced by Scleromyxedema.
Topics: Acute Febrile Encephalopathy; Biopsy; Blood Protein Electrophoresis; Brain; Coma; Diagnosis, Differe | 2020 |
38 other studies available for thyroxine and Seizures
| Article | Year |
|---|---|
Levothyroxine Treatment Among Pregnant Women and Risk of Seizure in Children: A Population-Based Cohort Study.
Topics: Cohort Studies; Female; Hong Kong; Humans; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effe | 2023 |
Maternal Thyroid Function in Early Pregnancy and Child Neurodevelopmental Disorders: A Danish Nationwide Case-Cohort Study.
Topics: Adult; Child; Child, Preschool; Denmark; Female; Fetal Development; Humans; Infant; Male; Neurodevel | 2018 |
Hashimoto's encephalopathy in children: different manifestations of five cases.
Topics: Adolescent; Adrenal Cortex Hormones; Child; Dysarthria; Dysphonia; Encephalitis; Female; Hashimoto D | 2019 |
Early-onset severe obesity with ACTH deficiency and red hair in a boy: the POMC deficiency.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Apnea; Caloric Restric | 2012 |
[Hashimoto encephalopathy].
Topics: Adrenal Cortex Hormones; Adult; Anticonvulsants; Antipsychotic Agents; Autoantibodies; Brain Disease | 2013 |
Subcortical band heterotopia in rat offspring following maternal hypothyroxinaemia: structural and functional characteristics.
Topics: Animals; Brain; Classical Lissencephalies and Subcortical Band Heterotopias; Dose-Response Relations | 2014 |
Endocrine encephalopathy.
Topics: Autoantibodies; Brain Diseases; Encephalitis; Female; Follow-Up Studies; Hashimoto Disease; Humans; | 2014 |
Central hypothyroidism and Sturge-Weber syndrome.
Topics: Anticonvulsants; Child; Female; Glaucoma; Humans; Hypothyroidism; Magnetic Resonance Imaging; Male; | 2008 |
Ward round--seizures, tremor and muscle weakness 20 years after thyroid surgery.
Topics: Adult; Brain; Humans; Hypothyroidism; Male; Muscle Weakness; Postoperative Complications; Seizures; | 2008 |
Congenital multiple pituitary hormone deficiency associated with hyperammonemia: a case report with a short review of the literature.
Topics: Drug Administration Schedule; Drug Monitoring; Female; Hormone Replacement Therapy; Humans; Hydrocor | 2011 |
Seizures and postictal stupor in a patient with uncontrolled Graves' hyperthyroidism.
Topics: Adolescent; Anticonvulsants; Antithyroid Agents; Diagnosis, Differential; Drug Therapy, Combination; | 2012 |
Effect of thyroxin, thyroidectomy and 6-n-propyl-2-thiouracil on brain function.
Topics: Brain; Electricity; Propylthiouracil; Seizures; Thiouracil; Thyroid Gland; Thyroidectomy; Thyroxine | 1952 |
Influence of thyroidectomy and thyroid hormones on electrically induced seizures in rabbits.
Topics: Animals; Electricity; Lagomorpha; Rabbits; Seizures; Thyroid Gland; Thyroid Hormones; Thyroidectomy; | 1953 |
Influence of the thyroid on the convulsive crises provoked in the rat.
Topics: Seizures; Thyroid Gland; Thyroxine; Viscera | 1955 |
[Comparative studies on the convulsive effects of insulin and N1-(4-methylbenzene-sulfonyl)-N2-butylurea in mice under normal metabolic conditions and conditions altered by thyroxin treatment].
Topics: Animals; Hypoglycemic Agents; Insulin; Mice; Seizures; Thyroxine; Urea | 1958 |
Observations on the early pharmacological effects of thyroxine.
Topics: Seizures; Thyroxine | 1960 |
Hashimoto's encephalopathy: a treatable cause of mental impairment, stroke and seizures.
Topics: Female; Humans; Memory Disorders; Mental Disorders; Middle Aged; Seizures; Stroke; Thyroiditis, Auto | 2003 |
Thyroxine-induced hypermotor seizure.
Topics: Child; Electroencephalography; Humans; Hyperkinesis; Hypothyroidism; Male; Seizures; Thyroxine | 2004 |
Seizure in a child after an acute ingestion of levothyroxine.
Topics: Child, Preschool; Humans; Male; Seizures; Thyroxine | 2005 |
Thyroid hormones do not alter rat brain benzodiazepine receptor function in-vivo.
Topics: Animals; Brain; Pentylenetetrazole; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Thyr | 1983 |
Thyroid hormone can restore the audiogenic seizure susceptibility of hypothyroid DBA/2J mice.
Topics: Acoustic Stimulation; Animals; Antithyroid Agents; Hypothyroidism; Mice; Mice, Inbred DBA; Seizures; | 1981 |
Genetic analysis of serum thyroxine content and audiogenic seizures in recombinant inbred and congenic strains of mice.
Topics: Acoustic Stimulation; Animals; Genetic Techniques; Mice; Mice, Inbred Strains; Recombination, Geneti | 1984 |
Effects of neonatal thyroxine, genotype, and noise on the ear and audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Auditory Perception; Genotype; Mice; Mice, Inbred C | 1981 |
Long-term antiepileptic effects of chronic intake of CNK-602A, a thyrotropin-releasing hormone analogue, on spontaneously epileptic rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Disease Models, Animal; Eating; Epilep | 1996 |
Normal serum free thyroid hormone concentrations in patients treated with phenytoin or carbamazepine. A paradox resolved.
Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Carrier Proteins; Humans; Phenytoin; Seizur | 1996 |
T3 deficiency prolongs convulsions induced by acute pentylenetetrazole.
Topics: Animals; Antithyroid Agents; Colon; Convulsants; Drug Overdose; Male; Methimazole; Pentylenetetrazol | 1997 |
[Variable manifestations of Hashimoto's encephalopathy].
Topics: Adult; Brain Diseases; Child; Electroencephalography; Female; Humans; Magnetic Resonance Imaging; Ma | 1999 |
Effects of phenobarbital treatment on serum thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anticonvulsants; Aspartate Aminotransferases; B | 1999 |
Thyroid hormone influence on the susceptibility of mice to audiogenic seizures.
Topics: Acoustic Stimulation; Animals; Hyperthyroidism; Hypothyroidism; Mice; Mice, Inbred Strains; Propylth | 1979 |
Disparity of effects of thyroxine and triiodothyronine on photic seizures and behavior in the baboon.
Topics: Animals; Behavior, Animal; Haplorhini; Heart Rate; Male; Papio; Photic Stimulation; Seizures; Thyrox | 1976 |
[Hypoglycemia in the collodion baby].
Topics: Blood Glucose; Growth Hormone; Humans; Hypoglycemia; Ichthyosis; Infant, Newborn; Insulin; Male; Sei | 1977 |
Unusual presentation of myxoedema coma in the elderly.
Topics: Aged; Cerebrovascular Disorders; Coma; Diagnosis, Differential; Female; Humans; Male; Myxedema; Seiz | 1977 |
Thyroid-function tests in diphenylhydantoin-treated patients.
Topics: Adult; Binding, Competitive; Female; Humans; Male; Phenytoin; Pregnancy; Protein Binding; Seizures; | 1975 |
Neurologic manifestations of cerebrovascular atherosclerosis associated with primary hypothyroidism in a dog.
Topics: Animals; Brain; Coma; Dog Diseases; Dogs; Female; Hypothyroidism; Intracranial Arteriosclerosis; Mus | 1985 |
Levothyroxine overdose associated with seizures in a young child.
Topics: Child, Preschool; Humans; Male; Seizures; Thyroxine; Time Factors; Triiodothyronine | 1985 |
The influence of thyroxine in photosensitive baboons Papio papio.
Topics: Animals; Cholesterol; Electroencephalography; Haplorhini; Light; Papio; Photic Stimulation; Seizures | 1974 |
Pharmacology of the adrenergic mechanism.
Topics: Amphetamine; Amphetamines; Animals; Anticonvulsants; Brain; Catecholamines; Cell Nucleus; Central Ne | 1974 |
Protection by catatoxic steroids and related compounds against proscillaridin intoxication.
Topics: Anabolic Agents; Androstanes; Animals; Bufanolides; Digitoxin; Ethylestrenol; Female; Glucocorticoid | 1972 |