alpha-methylhistamine has been researched along with Seizures in 2 studies
alpha-methylhistamine: a histamine H3 receptor agonist; RN given refers to parent cpd without isomeric designation
alpha-methylhistamine : An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of selective histamine H3-receptor antagonist thioperamide was studied on PTZ-induced seizures in mice." | 7.70 | Thioperamide, a selective histamine H3 receptor antagonist, protects against PTZ-induced seizures in mice. ( Pal, SN; Pillai, KK; Vohora, D, 2000) |
| "The effect of selective histamine H3-receptor antagonist thioperamide was studied on PTZ-induced seizures in mice." | 3.70 | Thioperamide, a selective histamine H3 receptor antagonist, protects against PTZ-induced seizures in mice. ( Pal, SN; Pillai, KK; Vohora, D, 2000) |
| "In amygdaloid kindled seizures, electrodes were implanted into the right amygdala and electroencephalogram was recorded bipolarly; stimulation was applied bipolarly every day by a constant current stimulator and continued until a generalized convulsion was obtained." | 1.32 | Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia. ( Fujii, Y; Harada, C; Harusawa, S; Hirai, T; Kamei, C; Kurihara, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, C | 1 |
| Hirai, T | 1 |
| Fujii, Y | 1 |
| Harusawa, S | 1 |
| Kurihara, T | 1 |
| Kamei, C | 1 |
| Vohora, D | 1 |
| Pal, SN | 1 |
| Pillai, KK | 1 |
2 other studies available for alpha-methylhistamine and Seizures
| Article | Year |
|---|---|
Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia.
Topics: Amygdala; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; | 2004 |
Thioperamide, a selective histamine H3 receptor antagonist, protects against PTZ-induced seizures in mice.
Topics: Animals; Dose-Response Relationship, Drug; Histamine Antagonists; Male; Methylhistamines; Mice; Pent | 2000 |