benserazide has been researched along with Seizures in 9 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
Excerpt | Relevance | Reference |
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" Amantadine in a dose of 25 mg/kg and particularly markedly in a dose of 100 mg/kg potentaites convulsive seizures." | 3.66 | On certain effects of dopaminergic agents in pentylenetetrazol convulsions. ( Lazarova, MB; Roussinov, KS, 1978) |
"A myoclonic syndrome consisting of tremor, myoclonus, and seizures was produced following the systemic administration of 5-hydroxytryptophan to adult rats previously given intracisternal injections of 5,7-dihydroxytryptamine and systemic desmethylimipramine, but not in their controls." | 3.65 | Myoclonus after 5-hydroxytryptophan in rats with lesions of indoleamine neurons in the central nervous system. ( Baldessarini, RJ; Cancian, D; Growdon, JH; Stewart, RM, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (77.78) | 18.7374 |
1990's | 1 (11.11) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (11.11) | 2.80 |
Authors | Studies |
---|---|
Al-Kaleel, A | 1 |
Erbaş, O | 1 |
Aygün, H | 1 |
Meerson, FZ | 1 |
Mamalyga, LM | 1 |
Thut, PD | 1 |
Myslinski, NR | 1 |
Dadkar, VN | 1 |
Dahanukar, SA | 1 |
Sheth, UK | 1 |
Lazarova, MB | 1 |
Roussinov, KS | 1 |
Kellogg, C | 1 |
Stewart, RM | 1 |
Growdon, JH | 1 |
Cancian, D | 1 |
Baldessarini, RJ | 1 |
Boggan, WO | 1 |
Seiden, LS | 1 |
Jobe, PC | 1 |
Stull, RE | 1 |
Geiger, PF | 1 |
9 other studies available for benserazide and Seizures
Article | Year |
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The effect of Madopar on absence‑like seizures in WAG/Rij rats.
Topics: Animals; Benserazide; Disease Models, Animal; Drug Combinations; Electroencephalography; Epilepsy, A | 2022 |
[The protective action of adaptation to hypoxia in audiogenic epilepsy and its prolongation by using pharmacologic agents].
Topics: Acoustic Stimulation; Adaptation, Physiological; Animals; Benserazide; Brain; Brain Chemistry; Drug | 1994 |
The role of dopamine and serotonin in the prolongation of post-decapitation convulsions in mice.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Decerebrate State; Ditiocarb; Dopamine; Fenclonine | 1976 |
Role of dopaminergic and noradrenergic mechanisms in Metrazole convulsions in mice.
Topics: Animals; Apomorphine; Benserazide; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; | 1979 |
On certain effects of dopaminergic agents in pentylenetetrazol convulsions.
Topics: Amantadine; Animals; Benserazide; Dextroamphetamine; Dopamine; Drug Interactions; Haloperidol; Levod | 1978 |
Audiogenic seizures: relation to age and mechanisms of monoamine neurotransmission.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Aging; Animals; Benserazide; Brain; Catecholamines; Dihyd | 1976 |
Myoclonus after 5-hydroxytryptophan in rats with lesions of indoleamine neurons in the central nervous system.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Dose-Response Relationship, Drug; Drug Interaction | 1976 |
5-Hydroxytryptophan reversal of reserpine enhancement of audiogenic seizure susceptibility in mice.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Be | 1973 |
The relative significance of norepinephrine, dopamine and 5-hydroxytryptamine in electroshock seizure in the rat.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Electr | 1974 |