3-hydroxyanthranilic acid has been researched along with Seizures in 3 studies
3-Hydroxyanthranilic Acid: An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
3-hydroxyanthranilic acid : An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.
3-hydroxyanthranilate : A hydroxybenzoate that is the conjugate base of 3-hydroxyanthranilic acid.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "mice subjected to PTZ-induced seizures provided an increase in the latency until onset of seizures, concomitant with a reduction in the severity of the seizures." | 1.31 | Anticonvulsant effects of the 3-hydroxyanthranilic acid dioxygenase inhibitor NCR-631. ( Luthman, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKiernan, J | 2 |
| Mellor, DH | 1 |
| Court, S | 2 |
| Mellor, D | 1 |
| Edson, J | 1 |
| Lacey, K | 1 |
| Luthman, J | 1 |
1 trial available for 3-hydroxyanthranilic acid and Seizures
| Article | Year |
|---|---|
A controlled trial of pyridoxine supplementation in children with febrile convulsions.
Topics: 3-Hydroxyanthranilic Acid; Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Kynur | 1981 |
2 other studies available for 3-hydroxyanthranilic acid and Seizures
| Article | Year |
|---|---|
Hydroxykynurenine/hydroxyanthranilic acid ratios and febrile convulsions.
Topics: 3-Hydroxyanthranilic Acid; Child, Preschool; Humans; Infant; Kynurenine; ortho-Aminobenzoates; Seizu | 1980 |
Anticonvulsant effects of the 3-hydroxyanthranilic acid dioxygenase inhibitor NCR-631.
Topics: 3-Hydroxyanthranilic Acid; Acoustic Stimulation; Animals; Anticonvulsants; Enzyme Inhibitors; Male; | 2000 |