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2,3-piperidinedicarboxylic acid and Seizures

2,3-piperidinedicarboxylic acid has been researched along with Seizures in 5 studies

2,3-piperidinedicarboxylic acid: effective antagonist at all three types of excitatory amino acid receptors; does not depress responses to acetylcholine or substance P

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Glutamic acid diethyl ester 1-3 mmol/kg has no effect on tremor or myoclonus, but increases the convulsion pressure when 3 mmol/kg is given immediately before compression."1.27Effect of excitatory amino acid antagonists on the high pressure neurological syndrome in rats. ( Meldrum, BS; Wardley-Smith, B, 1984)
"Protection against sound-induced seizures occurred after intraventricular administration of (+/-)cis-2,3-piperidine dicarboxylic acid (0."1.27Anticonvulsant and proconvulsant properties of a series of structural isomers of piperidine dicarboxylic acid. ( Collins, JF; Croucher, MJ; Meldrum, BS, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wardley-Smith, B1
Meldrum, BS3
Croucher, MJ2
Badman, G1
Collins, JF2
Daló, NL1
Larson, AA1
Dewhurst, DG1

Other Studies

5 other studies available for 2,3-piperidinedicarboxylic acid and Seizures

ArticleYear
Effect of excitatory amino acid antagonists on the high pressure neurological syndrome in rats.
    European journal of pharmacology, 1984, Oct-15, Volume: 105, Issue:3-4

    Topics: Animals; Glutamates; Male; Myoclonus; Pipecolic Acids; Pressure; Rats; Rats, Inbred Strains; Recepto

1984
Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, Papio papio.
    Neuroscience letters, 1983, Aug-19, Volume: 39, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Glutamates; Papio; Photic Stimul

1983
Anticonvulsant and proconvulsant properties of a series of structural isomers of piperidine dicarboxylic acid.
    Neuropharmacology, 1984, Volume: 23, Issue:4

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Female; Injections, I

1984
Spinal seizures evoked by sudden cooling of amphibian isolated spinal cords: involvement of excitatory amino acids.
    Cryobiology, 1991, Volume: 28, Issue:3

    Topics: Amino Acids; Animals; Anticonvulsants; Anura; Cold Temperature; Dipeptides; Glutamates; In Vitro Tec

1991
Possible role of excitatory amino acids in the convulsant action of catechol.
    European journal of pharmacology, 1988, Jan-12, Volume: 145, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Catechols; Dibenzocycloheptenes; Dipeptides; Dizo

1988