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methoxsalen and Seizures

methoxsalen has been researched along with Seizures in 2 studies

Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Tonic hind limb extension (seizure activity) was evoked in adult male albino Swiss mice by a current (25 mA, 500 V, 50 Hz, 0."1.42Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice. ( Florek-Luszczki, M; Glensk, M; Glowniak, K; Luszczki, JJ; Pyrka, D; Skalicka-Wozniak, K; Zagaja, M, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zagaja, M2
Pyrka, D2
Skalicka-Wozniak, K2
Glowniak, K1
Florek-Luszczki, M1
Glensk, M1
Luszczki, JJ1
Andres-Mach, M1
Patrzylas, P1
Szpringer, M1
Florek-Łuszczki, M1
Żółkowska, D1
Łuszczki, JJ1

Other Studies

2 other studies available for methoxsalen and Seizures

ArticleYear
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
    Fitoterapia, 2015, Volume: 105

    Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phen

2015
Influence of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of various novel antiepileptic drugs against maximal electroshock-induced seizures in mice.
    Fitoterapia, 2016, Volume: 115

    Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Fructose; Lacosam

2016