naltrexone and Seizures

naltrexone has been researched along with Seizures in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199022 (31.43)18.7374
1990's13 (18.57)18.2507
2000's17 (24.29)29.6817
2010's14 (20.00)24.3611
2020's4 (5.71)2.80

Authors

AuthorsStudies
Bassuk, AG; Cornell, RA; Glykys, J; Langton, R; Sharma, S; Sturgeon, ML1
Boroujeni, SS; Dehpour, AR; Jafari, RM; Karimi, E; Maleki, A; Mohammadi, P; Sabzevari, O; Shafaroodi, H; Solaimanian, S1
Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S1
Dehpour, AR; Haj-Mirzaian, A; Nikbakhsh, R; Noormohammady, P; Pirri, F; Radmard, M; Sabouri, M; Shababi, N; Tafazolimoghadam, A; Ziai, SA1
Amiri, S; Dehpour, AR; Ghasemi, M; Haj-Mirzaian, A; Hassanipour, M; Khoshnoodi, M; Ostadhadi, S; Shafaroodi, H; Sharifzadeh, M; Shirzadian, A1
Aghaei, I; Bahramnejad, E; Dehpour, AR; Kazemi Roodsari, S; Rahimi, N1
Akbarian, R; Moezi, L; Niknahad, H; Shafaroodi, H1
Abdolghaffari, AH; Aleyasin, AR; Azizi, Y; Chabouk, L; Dehpour, AR; Gooshe, M; Hassanzadeh, GR; Partoazar, A; Payandemehr, B; Tofigh, S1
Alijanpour, S; Amini-Khoei, H; Amiri, S; Dehpour, AR; Gooshe, M; Haj-Mirzaian, A; Hassanipour, M; Mehr, SE; Rahimi-Balaei, M; Shirzadian, A1
Abkhoo, A; Amiri, S; Boojar, MM; Dehpour, AR; Delazar, S; Hassanipour, M; Ostadhadi, S; Rahimi, N; Shirzadian, A1
Fakhrzad, A; Khosravani, E; Moezi, L; Shafaroodi, H1
Burtscher, J; Colmers, WF; MacKay, JP; Schwarzer, C; Zangrandi, L1
Dehpour, AR; Ghahremani, MH; Ghasemi, M; Rafiei-Tabatabaei, N; Riazi, K; Roshanpour, M1
Boyce, R; Leung, LS; Ma, J1
Baradaran, N; Dehpour, AR; Dehpour, S; Kabiri, T; Moezi, L; Shafaroodi, H1
Fujii, H; Nagase, H; Nemoto, T; Oka, J; Saitoh, A; Sugiyama, A; Wada, K; Yamada, M1
Chai, W; Gao, CJ; Li, YQ; Niu, L; Ren, PC; Sun, XD; Wang, W; Zhu, C1
Fichna, J; Gach, K; Janecka, A; Nieoczym, D; Perlikowska, R; Socała, K; Wlaź, P1
Ballachey, BE; McCormick, C; Monson, DH1
Bahadori, M; Dehpour, AR; Demehri, S; Homayoun, H; Honar, H; Riazi, K1
Dehpour, AR; Hajrasouliha, AR; Homayoun, H; Moezi, L; Sadeghipour, H; Samini, M; Shafaroodi, H; Tavakoli, S1
Dehghani, M; Dehpour, AR; Gaskari, SA; Homayoun, H; Honar, H; Rashidi, N; Riazi, K; Sadeghipour, H1
Dehpour, AR; Ebrahimkhani, MR; Homayoun, H; Honar, H; Mirazi, N; Rashidi, N; Riazi, K; Sadeghipour, H1
Jutkiewicz, EM; Rice, KC; Traynor, JR; Woods, JH1
Chang, KJ; Gengo, PJ; Gross, GJ; Holt, JD; O'Neill, SJ; Pendergast, W; Watson, MJ; Wei, K1
Beadles-Bohling, AS; Wiren, KM1
Adrian, R; Koob, GF; Solbrig, MV; Wechsler, SL1
Kaminski, RM; Shippenberg, TS; Witkin, JM1
Dehpour, AR; Ghasemi, M; Shafaroodi, H1
Dehpour, AR; Doratotaj, B; Gholipour, T; Honar, H; Jannati, A; Nik, HH; Noorian, AR; Riazi, K; Shariftabrizi, A1
Bahremand, A; Dehpour, AR; Ghasemi, M; Gholizadeh, S; Nasrabady, SE; Shafaroodi, H1
Holaday, JW; Tortella, FC1
Bajorek, JG; Lee, RJ; Lomax, P1
Balamuth, R; Frenk, H; Liban, A; Urca, G1
Cowan, A; Holaday, JW; Robles, LE; Tortella, FC1
Frenk, H; Mayer, DJ; Miller, J; Watkins, LR1
Frenk, H; Stein, BE1
Castellano, C; Csányl, V; Dóka, A; Oliverio, A; Puglisi-Allegra, S1
Lee, RJ; Lomax, P1
Carino, MA; Horita, A; Yamawaki, S1
Castellano, C; Oliverio, A; Puglisi-Allegra, S1
Lemaire, S; Shukla, VK1
Lasoń, W; Machelska, H; Przewłocka, B1
Ehrenreich, H; Poser, W1
Brusa, L; D'Amore, A; Lorenzini, P; Massotti, M1
Chang, KJ; Comer, SD; De Costa, BR; Hoenicke, EM; McNutt, RW; Mosberg, HI; Sable, AI; Woods, JH1
Gordon, FJ; Holtzman, SG; Patterson, AB1
Braida, D; Gori, E; Paladini, E; Sala, M1
Becker, A; Grecksch, G; Hoellt, V; Schroeder, H; Schroeder, U1
Becker, A; Grecksch, G; Höllt, V; Schroeder, H1
Misawa, M; Mizoguchi, H; Nagase, H; Narita, M; Suzuki, T; Takahashi-Nakano, Y; Tseng, LF; Yajima, Y1
Broom, DC; Coop, A; Guo, L; Husbands, SM; Lewis, JW; Traynor, JR; Woods, JH1
Dehpour, AR; Homayoun, H; Sayyah, M1
Baraban, JM; Bhat, RV; Cole, AJ; Worley, PF1
Goldberg, SR; Grayson, NA; Jaffe, JH; Johnson, RE; Katz, JL; Rice, KC; Witkin, JM1
Hughes, J; Hunter, JC; Singh, L; Vass, CA; Woodruff, GN1
Bencsik, K; Mihály, A; Solymosi, T1
Echevarria, E; Holaday, JW; Lipkowski, AW; Portoghese, PS; Takemori, AE; Tortella, FC1
Kotlińska, J; Langwiński, R1
Baratti, CM1
Laorden, ML; Miralles, FS; Puig, MM1
Holaday, JW; Robles, L; Tortella, FC1
Mansour, A; Valenstein, ES1
Cabib, S; Oliverio, A; Puglisi-Allegra, S1
Duka, T; Stephens, DN1
Mosberg, HI; Robles, L; Tortella, FC1
Frey, HH1
Bohus, B; Cottrell, GA1
Thompson, DF; Thompson, GD1

Other Studies

70 other study(ies) available for naltrexone and Seizures

ArticleYear
The opioid antagonist naltrexone decreases seizure-like activity in genetic and chemically induced epilepsy models.
    Epilepsia open, 2021, Volume: 6, Issue:3

    Topics: Animals; Epilepsy; Humans; Mice; Naltrexone; Narcotic Antagonists; Seizures; Zebrafish

2021
Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal electroshock in mice.
    Acta neurobiologiae experimentalis, 2022, Volume: 82, Issue:2

    Topics: Animals; Anticonvulsants; Chloroquine; Disease Models, Animal; Electroshock; Mefloquine; Mice; Naltrexone; Nitrites; Pentylenetetrazole; Seizures

2022
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K
    Toxicology and applied pharmacology, 2022, 11-01, Volume: 454

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Glyburide; Mice; Models, Theoretical; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Pentylenetetrazole; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Receptors, Opioid; Seizures; Stroke; Sumatriptan; Tumor Necrosis Factor-alpha

2022
The possible role of nitric oxide in anti-convulsant effects of Naltrindole in seizure-induced by social isolation stress in male mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Hippocampus; Male; Mice; Naltrexone; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase Type I; Pentylenetetrazole; Receptors, Opioid, delta; Seizures; Signal Transduction; Social Isolation; Stress, Psychological

2020
Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and cannabinoids.
    Epilepsy & behavior : E&B, 2018, Volume: 87

    Topics: Analgesics, Opioid; Animals; Cannabinoid Receptor Antagonists; Convulsants; Disease Models, Animal; Electroshock; Male; Mice; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Piperidines; Pyrazoles; Receptors, Cannabinoid; Seizures; Stress, Psychological

2018
Methadone's effects on pentylenetetrazole-induced seizure threshold in mice: NMDA/opioid receptors and nitric oxide signaling.
    Annals of the New York Academy of Sciences, 2019, Volume: 1449, Issue:1

    Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Guanidines; Indazoles; Ketamine; Male; Methadone; Mice; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Seizures

2019
The interaction of adenosine and morphine on pentylenetetrazole-induced seizure threshold in mice.
    Neuropharmacology, 2013, Volume: 72

    Topics: Adenosine; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Seizures; Xanthines

2013
Hypoxia/ischemia a key player in early post stroke seizures: modulation by opioidergic and nitrergic systems.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Analgesics, Opioid; Animals; Brain Ischemia; Cell Hypoxia; Drug Synergism; GABA Antagonists; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Stroke

2015
Morphine modulates the effects of histamine H1 and H3 receptors on seizure susceptibility in pentylenetetrazole-induced seizure model of mice.
    European journal of pharmacology, 2015, Dec-15, Volume: 769

    Topics: Animals; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Histamine Agonists; Histamine Antagonists; Male; Mice; Morphine; Naltrexone; Pentylenetetrazole; Receptors, Histamine H1; Receptors, Histamine H3; Seizures

2015
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
    Brain research bulletin, 2016, Volume: 121

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors

2016
The interaction between morphine and propranolol in chemical and electrical seizure models of mice.
    Neurological research, 2016, Volume: 38, Issue:2

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Electroshock; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Propranolol; Seizures; Time Factors

2016
The G-protein biased partial κ opioid receptor agonist 6'-GNTI blocks hippocampal paroxysmal discharges without inducing aversion.
    British journal of pharmacology, 2016, Volume: 173, Issue:11

    Topics: Animals; Guanidines; Heterotrimeric GTP-Binding Proteins; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Receptors, Opioid, kappa; Seizures

2016
Tolerance to the anticonvulsant effect of morphine in mice: blockage by ultra-low dose naltrexone.
    Epilepsy research, 2009, Volume: 83, Issue:2-3

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Seizures

2009
Nucleus accumbens mu opioid receptors mediate immediate postictal decrease in locomotion after an amygdaloid kindled seizure in rats.
    Epilepsy & behavior : E&B, 2010, Volume: 17, Issue:2

    Topics: Amygdala; Animals; Epilepsy; Kindling, Neurologic; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Opioid, mu; Seizures

2010
New obesity pill: new hopes, old fears.
    Lancet (London, England), 2010, Dec-18, Volume: 376, Issue:9758

    Topics: Anti-Obesity Agents; Antidepressive Agents, Second-Generation; Bupropion; Cardiovascular Diseases; Dopamine Uptake Inhibitors; Drug Approval; Drug Combinations; Exercise; Feeding Behavior; Humans; Life Style; Naltrexone; Narcotic Antagonists; Obesity; Seizures; Suicidal Ideation; United States; United States Food and Drug Administration

2010
Morphine sensitization in the pentylenetetrazole-induced clonic seizure threshold in mice: role of nitric oxide and μ receptors.
    Epilepsy & behavior : E&B, 2011, Volume: 20, Issue:4

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, Opioid, mu; Seizures

2011
The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions.
    Behavioural brain research, 2011, Oct-01, Volume: 223, Issue:2

    Topics: Analgesics; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzamides; Depression; Dopamine Antagonists; Imipramine; Male; Mice; Mice, Inbred ICR; Morphinans; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Receptors, Opioid, delta; Seizures; Swimming

2011
Hypoxic preconditioning attenuates global cerebral ischemic injury following asphyxial cardiac arrest through regulation of delta opioid receptor system.
    Neuroscience, 2012, Jan-27, Volume: 202

    Topics: Animals; Apoptosis; Arousal; Asphyxia; Behavior, Animal; Blotting, Western; Brain Ischemia; Brain Stem; Enkephalin, Leucine; Fluorescent Antibody Technique; Heart Arrest; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; In Situ Nick-End Labeling; Ischemic Preconditioning; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Postural Balance; Rats; Real-Time Polymerase Chain Reaction; Receptors, Opioid, delta; RNA, Small Interfering; Seizures; Survival Analysis

2012
The mu-opioid receptor-selective peptide antagonists, antanal-1 and antanal-2, produce anticonvulsant effects in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jan-10, Volume: 40

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hand Strength; Male; Mice; Muscle Strength; Naltrexone; Oligopeptides; Pentylenetetrazole; Receptors, Opioid, mu; Seizures

2013
Chemical anesthesia of northern sea otters (Enhydra lutris): results of past field studies.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2001, Volume: 32, Issue:2

    Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Azaperone; Body Temperature; Diazepam; Female; Fentanyl; Heart Rate; Hypnotics and Sedatives; Immobilization; Logistic Models; Male; Naloxone; Naltrexone; Narcotic Antagonists; Otters; Respiration; Seizures; Time Factors; Tremor

2001
Intestinal inflammation alters the susceptibility to pentylenetetrazole-induced seizure in mice.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:3

    Topics: Animals; Convulsants; Enteritis; Male; Mice; Naltrexone; Pentylenetetrazole; Seizures

2004
The interaction of cannabinoids and opioids on pentylenetetrazole-induced seizure threshold in mice.
    Neuropharmacology, 2004, Volume: 47, Issue:3

    Topics: Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentylenetetrazole; Piperidines; Pyrazoles; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Opioid; Seizures; Statistics, Nonparametric; Time Factors

2004
Sex and estrus cycle differences in the modulatory effects of morphine on seizure susceptibility in mice.
    Epilepsia, 2004, Volume: 45, Issue:9

    Topics: Animals; Anticonvulsants; Convulsants; Disease Susceptibility; Dose-Response Relationship, Drug; Estrous Cycle; Female; Gonadal Steroid Hormones; Infusions, Intravenous; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Orchiectomy; Ovariectomy; Pentylenetetrazole; Seizures; Sex Factors

2004
Ultra-low dose naltrexone potentiates the anticonvulsant effect of low dose morphine on clonic seizures.
    Neuroscience, 2004, Volume: 129, Issue:3

    Topics: Animals; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentylenetetrazole; Reaction Time; Seizures

2004
Separation of the convulsions and antidepressant-like effects produced by the delta-opioid agonist SNC80 in rats.
    Psychopharmacology, 2005, Volume: 182, Issue:4

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Male; Naltrexone; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Restraint, Physical; Seizures; Swimming; Time Factors; Tritium

2005
ARD-353 [4-((2R,5S)-4-(R)-(4-diethylcarbamoylphenyl)(3-hydroxyphenyl)methyl)-2,5-dimethylpiperazin-1-ylmethyl)benzoic acid], a novel nonpeptide delta receptor agonist, reduces myocardial infarct size without central effects.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 316, Issue:1

    Topics: Animals; Benzoates; Benzylidene Compounds; Binding, Competitive; Cardiotonic Agents; Catalepsy; Dose-Response Relationship, Drug; Hemodynamics; In Vitro Techniques; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Naltrexone; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Seizures

2006
Anticonvulsive effects of kappa-opioid receptor modulation in an animal model of ethanol withdrawal.
    Genes, brain, and behavior, 2006, Volume: 5, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol-Induced Disorders, Nervous System; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anticonvulsants; Brain; Central Nervous System Depressants; Disease Models, Animal; Drug Interactions; Drug Synergism; Ethanol; Male; Naltrexone; Receptors, Opioid, kappa; Seizures; Species Specificity; Substance Withdrawal Syndrome; Treatment Outcome

2006
Activators of potassium M currents have anticonvulsant actions in two rat models of encephalitis.
    European journal of pharmacology, 2007, Jan-19, Volume: 555, Issue:1

    Topics: Aminopyridines; Analgesics; Animals; Anticonvulsants; Borna Disease; Encephalitis, Viral; Herpes Simplex; Herpesvirus 1, Human; Male; Naloxone; Naltrexone; Narcotic Antagonists; Potassium; Rats; Rats, Inbred Lew; Receptors, Opioid, delta; Seizures; Substance Withdrawal Syndrome

2007
Pharmacological and genetic manipulation of kappa opioid receptors: effects on cocaine- and pentylenetetrazol-induced convulsions and seizure kindling.
    Neuropharmacology, 2007, Volume: 52, Issue:3

    Topics: Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Pyrrolidines; Receptors, Opioid, kappa; Seizures

2007
Elevation of pentylenetetrazole-induced seizure threshold in cholestatic mice: interaction between opioid and cannabinoid systems.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:7 Pt 2

    Topics: Animals; Anticonvulsants; Bile Ducts; Cannabinoid Receptor Modulators; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Ligation; Male; Mice; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pentylenetetrazole; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid; Seizures; Time Factors

2008
Seizure susceptibility alteration following reversible cholestasis in mice: Modulation by opioids and nitric oxide.
    European journal of pharmacology, 2008, Feb-12, Volume: 580, Issue:3

    Topics: 1-Naphthylisothiocyanate; Alkaline Phosphatase; Animals; Bilirubin; Biomarkers; Cholestasis; Corn Oil; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Infusions, Intravenous; Intubation, Gastrointestinal; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Receptors, Opioid; Seizures; Time Factors

2008
The cannabinoid anticonvulsant effect on pentylenetetrazole-induced seizure is potentiated by ultra-low dose naltrexone in mice.
    Epilepsy research, 2008, Volume: 81, Issue:1

    Topics: Animals; Anticonvulsants; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoids; Convulsants; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Injections, Intraperitoneal; Male; Mice; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Piperidines; Pyrazoles; Seizures

2008
Mu and delta opioid receptor interactions in a rat model of drug induced seizures.
    Proceedings of the Western Pharmacology Society, 1984, Volume: 27

    Topics: Animals; Disease Models, Animal; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1984
Opioid peptides and seizures in the spontaneously epileptic Mongolian gerbil.
    Life sciences, 1983, Volume: 33 Suppl 1

    Topics: Animals; beta-Endorphin; Cerebral Cortex; Dynorphins; Endorphins; Enkephalin, Methionine; Epilepsy; Gerbillinae; Morphine; Naltrexone; Narcotics; Seizures

1983
Opiate and non-opiate aspects of morphine induced seizures.
    Brain research, 1982, Dec-16, Volume: 253, Issue:1-2

    Topics: Amygdala; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Evoked Potentials; Injections, Intraperitoneal; Kindling, Neurologic; Male; Morphine; Motor Activity; Muridae; Naltrexone; Nociceptors; Receptors, Opioid; Seizures

1982
ICI 154,129, a delta-opioid receptor antagonist raises seizure threshold in rats.
    European journal of pharmacology, 1984, Jan-13, Volume: 97, Issue:1-2

    Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures

1984
Nonspecific convulsions are induced by morphine but not D-Ala2-methionine-enkephalinamide at cortical sites.
    Brain research, 1984, May-07, Volume: 299, Issue:1

    Topics: Animals; Cerebral Cortex; Drug Tolerance; Electroencephalography; Enkephalin, Methionine; Evoked Potentials; Injections, Intraventricular; Male; Methadone; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures

1984
Endogenous opioids mediate ECS-induced catalepsy at supraspinal levels.
    Brain research, 1984, Jun-11, Volume: 303, Issue:1

    Topics: Animals; Brain; Catalepsy; Electroshock; Endorphins; Humans; Male; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures; Spinal Cord

1984
Opioid antagonism of electroshock-induced seizures.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:5

    Topics: Animals; beta-Endorphin; Electroshock; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotics; Seizures; Time Factors

1984
The effect of spontaneous seizures on pentylenetetrazole and maximum electroshock induced seizures in the Mongolian gerbil.
    European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1

    Topics: Animals; Disease Models, Animal; Electroshock; Endorphins; Epilepsy; Female; Gerbillinae; Male; Models, Neurological; Naltrexone; Pentylenetetrazole; Seizures

1984
Morphine antagonizes pentobarbital-induced anesthesia.
    Neuropharmacology, 1983, Volume: 22, Issue:10

    Topics: Anesthesia; Animals; Atropine; Behavior, Animal; Electroencephalography; Male; Morphine; Naloxone; Naltrexone; Pentobarbital; Rabbits; Seizures

1983
Anticonvulsant effects of stress: role of endogenous opioids.
    Brain research, 1983, Jul-18, Volume: 271, Issue:1

    Topics: Animals; Anticonvulsants; Endorphins; Male; Mice; Mice, Inbred C57BL; Naltrexone; Restraint, Physical; Seizures; Stress, Physiological

1983
Norbinaltorphimine protection against N-methyl-D-aspartic acid-induced convulsions and mortality.
    European journal of pharmacology, 1993, Feb-09, Volume: 231, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bicuculline; Binding, Competitive; Brain; Ibotenic Acid; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Naltrexone; Receptors, N-Methyl-D-Aspartate; Seizures

1993
Kappa opioid receptor agonists inhibit the pilocarpine-induced seizures and toxicity in the mouse.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:4

    Topics: Analgesics; Animals; Benzeneacetamides; Brain; Injections, Intraperitoneal; Mice; Naltrexone; Pilocarpine; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Seizures; Thiophenes

1994
Dependence on tramadol.
    The Clinical investigator, 1993, Volume: 72, Issue:1

    Topics: Adult; Drug Tolerance; Euphoria; Female; Humans; Naltrexone; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Tramadol

1993
Area tempestas modulates the behavioural responses to nociceptive stimuli in rats.
    Annali dell'Istituto superiore di sanita, 1993, Volume: 29, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Azocines; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Escape Reaction; Foot; Hot Temperature; Male; Morphine; Naltrexone; Narcotic Antagonists; Olfactory Pathways; Pain; Phenazocine; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Seizures; Tail

1993
Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Amino Acid Sequence; Animals; Anticonvulsants; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Midazolam; Molecular Sequence Data; Naltrexone; Pentylenetetrazole; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1993
Naltrindole, a selective delta-opioid receptor antagonist, potentiates the lethal effects of cocaine by a central mechanism of action.
    European journal of pharmacology, 1997, Aug-20, Volume: 333, Issue:1

    Topics: Animals; Blood Pressure; Central Nervous System; Cisterna Magna; Cocaine; Drug Synergism; Heart Rate; Infusions, Intravenous; Injections; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Seizures

1997
Naltrexone, naltrindole, and CTOP block cocaine-induced sensitization to seizures and death.
    Peptides, 1997, Volume: 18, Issue:8

    Topics: Animals; Cocaine-Related Disorders; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures; Somatostatin

1997
The effect of pentylenetetrazol kindling on synaptic mechanisms of interacting glutamatergic and opioid system in the hippocampus of rats.
    Brain research, 1998, Nov-16, Volume: 811, Issue:1-2

    Topics: Animals; Convulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Opioid; Seizures; Synapses

1998
Involvement of delta-opioid receptors in pentylenetetrazol kindling development and kindling-related processes in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:2

    Topics: Animals; Convulsants; Drug Interactions; Glutamic Acid; Injections, Intraventricular; Kindling, Neurologic; Learning Disabilities; Male; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Opioid, delta; Seizures; Time Factors

1999
Effects of differential modulation of mu-, delta- and kappa-opioid systems on bicuculline-induced convulsions in the mouse.
    Brain research, 2000, Apr-17, Volume: 862, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Bicuculline; Brain Chemistry; Convulsants; Enkephalin, D-Penicillamine (2,5)-; Epilepsy, Tonic-Clonic; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Quinolines; Receptors, GABA-A; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures; Synaptic Transmission

2000
BU48: a novel buprenorphine analog that exhibits delta-opioid-mediated convulsions but not delta-opioid-mediated antinociception in mice.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Analgesics, Opioid; Animals; Benzamides; Brain; Buprenorphine; Convulsants; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Seizures; Vas Deferens

2000
The additive effect of opioids and nitric oxide in increasing pentylenetetrazole-induced seizure threshold in cholestatic mice.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:1

    Topics: Animals; Cholestasis; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures

2002
Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268.
    Brain research. Molecular brain research, 1992, Volume: 13, Issue:3

    Topics: Animals; Apomorphine; Benzazepines; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Electroshock; Haloperidol; Immediate-Early Proteins; Male; Morphine; Naltrexone; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Substance Withdrawal Syndrome; Transcription Factors; Transcription, Genetic; Zinc Fingers

1992
The partial opioid agonist, buprenorphine, protects against lethal effects of cocaine.
    Drug and alcohol dependence, 1991, Volume: 27, Issue:2

    Topics: Animals; Brain; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Methadone; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Receptors, Opioid; Receptors, Opioid, mu; Seizures

1991
The anticonvulsant action of CI-977, a selective kappa-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex.
    European journal of pharmacology, 1990, Dec-04, Volume: 191, Issue:3

    Topics: Animals; Anticonvulsants; Benzofurans; Dizocilpine Maleate; In Vitro Techniques; Mice; Mice, Inbred Strains; Naltrexone; Piperazines; Pyrrolidines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Stereoisomerism

1990
Naltrexone potentiates 4-aminopyridine seizures in the rat.
    Journal of neural transmission. General section, 1990, Volume: 79, Issue:1-2

    Topics: 4-Aminopyridine; Animals; Convulsants; Dose-Response Relationship, Drug; Female; Naltrexone; Rats; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu; Seizures

1990
Selective kappa antagonist properties of nor-binaltorphimine in the rat MES seizure model.
    Life sciences, 1989, Volume: 44, Issue:10

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naltrexone; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Seizures

1989
Does the blockade of opioid receptors influence the development of ethanol dependence?
    Alcohol and alcoholism (Oxford, Oxfordshire), 1987, Volume: 22, Issue:2

    Topics: Alcoholism; Animals; Diprenorphine; Female; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures; Substance Withdrawal Syndrome

1987
The impairment of retention induced by pentylenetetrazol in mice may be mediated by a release of opioid peptides in the brain.
    Behavioral and neural biology, 1987, Volume: 48, Issue:2

    Topics: Animals; Avoidance Learning; Benzomorphans; beta-Endorphin; Brain; Dose-Response Relationship, Drug; Male; Memory; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Quaternary Ammonium Compounds; Receptors, Opioid; Retention, Psychology; Seizures

1987
High doses of L-naloxone but neither D-naloxone nor beta-funaltrexamine prevent hyperthermia-induced seizures in rat pups.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:3

    Topics: Animals; Body Temperature; Hyperthermia, Induced; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism

1988
The anticonvulsant effects of DADLE are primarily mediated by activation of delta opioid receptors: interactions between delta and mu receptor antagonists.
    Life sciences, 1985, Aug-12, Volume: 37, Issue:6

    Topics: Animals; Anticonvulsants; Cerebral Ventricles; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1985
Changes in responsiveness to mu and kappa opiates following a series of convulsions.
    Experimental neurology, 1985, Volume: 90, Issue:1

    Topics: Animals; Codeine; Dose-Response Relationship, Drug; Electroshock; Levorphanol; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotics; Receptors, Opioid; Seizures

1985
Pharmacological evidence for a protective role of the endogenous opioid system on electroshock-induced seizures in the mouse.
    Neuroscience letters, 1985, Dec-04, Volume: 62, Issue:2

    Topics: Animals; Electroshock; Endorphins; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seizures; Time Factors

1985
Potentiation of the propunishment, but not the convulsant action of the beta-carboline DMCM by naltrexone.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:3

    Topics: Animals; Anxiety; Carbolines; Drug Synergism; Female; Male; Mice; Motor Activity; Naltrexone; Punishment; Receptors, GABA-A; Receptors, Opioid; Seizures

1986
Evidence for mu opioid receptor mediation of enkephalin-induced electroencephalographic seizures.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2

    Topics: Animals; Electroencephalography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1987
Endogenous opioids and post-ictal increase in seizure threshold in Mongolian gerbils.
    Epilepsy research, 1987, Volume: 1, Issue:2

    Topics: Animals; Electric Stimulation; Endorphins; Gerbillinae; Morphine; Naloxone; Naltrexone; Pentylenetetrazole; Seizures

1987
Immediate and long-term effects of opiate antagonists on postictal behaviour following amygdala kindling in the rat.
    European journal of pharmacology, 1987, Sep-23, Volume: 141, Issue:3

    Topics: Amygdala; Animals; Behavior, Animal; Electric Stimulation; Kindling, Neurologic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Seizures

1987
Naltrexone in the management of seizures associated with Rett syndrome.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:11

    Topics: Autistic Disorder; Female; Gait; Humans; Naltrexone; Seizures; Syndrome

1987