Page last updated: 2024-08-24

tiagabine and Seizures

tiagabine has been researched along with Seizures in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (26.67)	18.2507
2000's	23 (51.11)	29.6817
2010's	7 (15.56)	24.3611
2020's	3 (6.67)	2.80

Authors

Authors	Studies
Szabó, CÁ; Tanwir, A	1
Ahmad, T; Alasmari, AF; Alasmari, F; Alqahtani, F; Alqarni, SA; Anjum, SMM; Ashraf, W; Imran, I; Javaid, S; Rasool, MF	1
Chuang, SH; Reddy, DS	1
Dunn, R; Forcelli, PA; Pak, DTS; Queenan, BN	1
Nieoczym, D; Socała, K; Szafarz, M; Wlaź, P; Wyska, E	1
Catterall, WA; Cheah, CS; Cho, AR; Oakley, JC; Scheuer, T	1
Beck, VC; Forcelli, PA; Gutherz, SB; Kulick, CV; Medvedeva, N; Soper, C	1
Dziubina, A; Filipek, B; Kowalczyk, P; Kulig, K; Librowski, T; Podkowa, A; Sałat, K	1
Luszczki, JJ	1
Dang, CV; Nelson, L; Wade, JF; Wasserberger, J	1
Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sielski, M	1
Krzyzanowski, M; Luszczki, JJ; Swiader, MJ	1
Clausen, RP; Krogsgaard-Larsen, P; Larsson, OM; Madsen, KK; Schousboe, A; White, HS	1
Clausen, RP; Danbolt, NC; Guo, C; Holen, T; Holmseth, S; Hua, R; Laake, P; Lehre, AC; Madsen, KK; Olofsson, AM; Poblete-Naredo, I; Rowley, NM; Rusakov, DA; Schousboe, A; White, HS; Zhou, Y	1
Endo, Y; Fueta, Y; Mita, T; Ohno, K; Schwarz, W	1
Angehagen, M; Ben-Menachem, E; Hansson, E; Rönnbäck, L	1
Sills, GJ	1
Czuczwar, M; Czuczwar, SJ; Kiś, J; Swiader, M; Łuszczki, J	1
Czuczwar, SJ; Luszczki, JJ	2
Danhof, M; Jonker, DM; Voskuyl, RA	1
Korpi, ER; Möykkynen, T; Ogris, W; Sieghart, W; Sinkkonen, ST; Vekovischeva, OY; Wisden, W	1
Bolvig, T; Clausen, RP; Falch, E; Frølund, B; Hansen, SL; Krogsgaard-Larsen, P; Larsson, OM; Perregaard, J; Petersen, G; Sarup, A; Schousboe, A; Slough, S; Watson, WP; White, HS	1
Jedrzejczak, J	1
Fueta, Y; Kunugita, N; Schwarz, W	1
Flowers, CM; Kortepeter, C; Racoosin, JA	1
Dhir, A; Kulkarni, SK	1
Chodorowski, Z; Kosińska-Tomczyk, H; Sein Anand, J; Wiśniewski, M	1
Auvinen, A; Keränen, T; Kharazmi, E; Peltola, J; Peltola, M; Raitanen, J	1
Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K	1
Jansen, JA; Suzdak, PD	1
Suzdak, PD	1
Anderson, CA; Faingold, CL; Randall, ME	1
Mengel, H	1
Davies, JA; Hu, RQ	1
Boellner, SW; Cao, GX; Cato, A; Guenther, HJ; Gustavson, LE; Qian, JX; Sommerville, KW	1
Boellner, SW; Granneman, GR; Guenther, HJ; Gustavson, LE; Sommerville, KW; Witt, GF	1
Dalby, NO	1
Haugvicová, R; Kubová, H; Mares, P; Skutová, M; Suchomelová, L	1
Vaughn, BV; Zhu, Y	1
Fink-Jensen, A; Hansen, L; Judge, ME; Nielsen, PG; Suzdak, PD; Swedberg, MD	1
Andersen, KE; Frederiksen, K; Knutsen, LJ; Nielsen, EB; Suzdak, PD; Sørensen, PO	1
Browne, SE; Pertwee, RG; Ross, TM; Stretton, CD	1
Andersen, KE; Braestrup, C; Knutsen, LJ; Nielsen, EB; Sonnewald, U; Suzdak, PD	1

Reviews

6 review(s) available for tiagabine and Seizures

Article	Year
Emergent complications of the newer anticonvulsants. The Journal of emergency medicine, 2010, Volume: 38, Issue:2 Topics: Acidosis; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Overdose; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Psychoses, Substance-Induced; Seizures; Tiagabine; Topiramate; Triazines	2010
Novel mechanisms of action of three antiepileptic drugs, vigabatrin, tiagabine, and topiramate. Neurochemical research, 2003, Volume: 28, Issue:2 Topics: Anticonvulsants; Fructose; Neuroprotective Agents; Nipecotic Acids; Seizures; Tiagabine; Topiramate; Vigabatrin	2003
Pre-clinical studies with the GABAergic compounds vigabatrin and tiagabine. Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5, Issue:1 Topics: Animals; Anticonvulsants; GABA Agonists; Humans; Nipecotic Acids; Receptors, GABA; Seizures; Tiagabine; Vigabatrin; Visual Fields	2003
[Caffeine and antiepileptic drugs: experimental and clinical data]. Przeglad lekarski, 2007, Volume: 64, Issue:11 Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid	2007
A review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant GABA uptake inhibitor. Epilepsia, 1995, Volume: 36, Issue:6 Topics: Animals; Anticonvulsants; Behavior, Animal; Brain Ischemia; Dogs; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Kindling, Neurologic; Mice; Mice, Inbred DBA; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Rats; Receptors, GABA; Seizures; Self Administration; Tiagabine	1995
Tiagabine. Epilepsia, 1994, Volume: 35 Suppl 5 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Interactions; Epilepsy, Complex Partial; Humans; Male; Mice; Nipecotic Acids; Rats; Rats, Wistar; Seizures; Tiagabine	1994

Trials

3 trial(s) available for tiagabine and Seizures

Article	Year
Tiagabine as add-on therapy may be more effective with valproic acid--open label, multicentre study of patients with focal epilepsy. European journal of neurology, 2005, Volume: 12, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Nipecotic Acids; Poland; Seizures; Sex Factors; Tiagabine; Treatment Outcome; Valproic Acid	2005
Lack of pharmacokinetic drug interactions between tiagabine and carbamazepine or phenytoin. American journal of therapeutics, 1998, Volume: 5, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dizziness; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; GABA Agonists; Headache; Humans; Male; Middle Aged; Nipecotic Acids; Phenytoin; Seizures; Sleep Stages; Tiagabine; Tremor	1998
Lack of a clinically significant pharmacokinetic drug interaction between tiagabine and valproate. American journal of therapeutics, 1998, Volume: 5, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Dizziness; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; GABA Agonists; Humans; Male; Nipecotic Acids; Rhinitis; Seizures; Sleep Stages; Tiagabine; Time Factors; Tremor; Valproic Acid	1998

Other Studies

36 other study(ies) available for tiagabine and Seizures

Article	Year
Non-convulsive status epilepticus in the setting of cannabidiol adjunctive therapy Epileptic disorders : international epilepsy journal with videotape, 2022, 08-01, Volume: 24, Issue:4 Topics: Anticonvulsants; Cannabidiol; Child; Confusion; Drug Resistant Epilepsy; Electroencephalography; Humans; Male; Middle Aged; Seizures; Status Epilepticus; Tiagabine	2022
Tiagabine suppresses pentylenetetrazole-induced seizures in mice and improves behavioral and cognitive parameters by modulating BDNF/TrkB expression and neuroinflammatory markers. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 160 Topics: Animals; Anticonvulsants; Brain-Derived Neurotrophic Factor; Cognition; Epilepsy; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; RNA, Messenger; Seizures; Tiagabine	2023
Isobolographic Analysis of Antiseizure Activity of the GABA Type A Receptor-Modulating Synthetic Neurosteroids Brexanolone and Ganaxolone with Tiagabine and Midazolam. The Journal of pharmacology and experimental therapeutics, 2020, Volume: 372, Issue:3 Topics: Animals; Anticonvulsants; beta-Cyclodextrins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Midazolam; Neurosteroids; Patch-Clamp Techniques; Pregnanolone; Receptors, GABA-A; Seizures; Tiagabine	2020
Divergent effects of levetiracetam and tiagabine against spontaneous seizures in adult rats following neonatal hypoxia. Epilepsy research, 2018, Volume: 140 Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Hypoxia; Levetiracetam; Male; Phenobarbital; Prohibitins; Rats, Long-Evans; Seizures; Tiagabine	2018
Acute effect of cannabidiol on the activity of various novel antiepileptic drugs in the maximal electroshock- and 6 Hz-induced seizures in mice: Pharmacodynamic and pharmacokinetic studies. Neuropharmacology, 2019, 11-01, Volume: 158 Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Drug Resistant Epilepsy; Electric Stimulation; Gabapentin; Lacosamide; Lamotrigine; Levetiracetam; Male; Mice; Oxcarbazepine; Pregabalin; Seizures; Tiagabine; Topiramate	2019
Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome. The Journal of pharmacology and experimental therapeutics, 2013, Volume: 345, Issue:2 Topics: Animals; Anticonvulsants; Clonazepam; Dose-Response Relationship, Drug; Drug Synergism; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hot Temperature; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NAV1.1 Voltage-Gated Sodium Channel; Nipecotic Acids; Postural Balance; Seizures; Synaptic Transmission; Tiagabine	2013
Profile of anticonvulsant action of levetiracetam, tiagabine and phenobarbital against seizures evoked by DMCM (methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate) in neonatal rats. European journal of pharmacology, 2014, Nov-15, Volume: 743 Topics: Animals; Animals, Newborn; Anticonvulsants; Carbolines; Levetiracetam; Male; Nipecotic Acids; Phenobarbital; Piracetam; Rats; Rats, Sprague-Dawley; Seizures; Tiagabine	2014
Anticonvulsant active inhibitor of GABA transporter subtype 1, tiagabine, with activity in mouse models of anxiety, pain and depression. Pharmacological reports : PR, 2015, Volume: 67, Issue:3 Topics: Animals; Anticonvulsants; Anxiety; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Male; Mice; Nipecotic Acids; Pain; Seizures; Tiagabine	2015
Interactions of tiagabine with ethosuximide in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves. Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:5 Topics: Animals; Anticonvulsants; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fluorescence Polarization Immunoassay; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine; Tissue Distribution	2008
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis. European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3 Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin	2009
Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves. Advances in medical sciences, 2009, Volume: 54, Issue:1 Topics: Animals; Anticonvulsants; Brain Chemistry; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Random Allocation; Seizures; Tiagabine; Valproic Acid	2009
Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs. Journal of neurochemistry, 2009, Volume: 109 Suppl 1 Topics: Acoustic Stimulation; Animals; Anisoles; Anticonvulsants; Behavior, Animal; Carrier Proteins; Cornea; Female; GABA Agonists; GABA Plasma Membrane Transport Proteins; Kindling, Neurologic; Male; Mice; Neuroprotective Agents; Nipecotic Acids; Seizures; Synapses; Tiagabine	2009
Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. Epilepsy research, 2011, Volume: 95, Issue:1-2 Topics: Animals; Anticonvulsants; Convulsants; Crosses, Genetic; Dose-Response Relationship, Drug; Electroshock; Exons; Female; GABA Plasma Membrane Transport Proteins; Isoxazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nipecotic Acids; Pentylenetetrazole; RNA, Messenger; Seizures; Tiagabine	2011
Selective suppression of hippocampal region hyperexcitability related to seizure susceptibility in epileptic El mice by the GABA-transporter inhibitor tiagabine. Brain research, 2002, Aug-30, Volume: 947, Issue:2 Topics: Animals; Anticonvulsants; Dentate Gyrus; Electrophysiology; Epilepsy; Female; GABA Agonists; Hippocampus; Male; Mice; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Seizures; Tiagabine	2002
Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice. Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:2 Topics: Animals; Anticonvulsants; Brain; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Drug Synergism; Electroshock; Fluorescent Antibody Technique; Male; Mice; Motor Activity; Nipecotic Acids; Psychomotor Performance; Seizures; Spectrophotometry, Ultraviolet; Tiagabine	2003
Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4 Topics: Amines; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine	2004
Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat. Epilepsia, 2004, Volume: 45, Issue:5 Topics: Animals; Anticonvulsants; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroencephalography; Electroshock; Epilepsy; Humans; Lamotrigine; Male; Nipecotic Acids; Rats; Rats, Wistar; Seizures; Tiagabine; Triazines	2004
Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model. The European journal of neuroscience, 2004, Volume: 20, Issue:8 Topics: Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neural Inhibition; Nipecotic Acids; Protein Binding; Receptors, GABA-A; Reflex, Startle; Seizures; Synapses; Tiagabine	2004
First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2 Topics: Acoustic Stimulation; Acyltransferases; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Cells, Cultured; Cloning, Molecular; Convulsants; Drug Synergism; Epilepsy; Epilepsy, Reflex; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; N-Acetylglucosaminyltransferases; Neurons; Nipecotic Acids; Pentylenetetrazole; Pilocarpine; Psychomotor Disorders; Recombinant Proteins; Seizures; Tiagabine	2005
Antiepileptic action induced by a combination of vigabatrin and tiagabine. Neuroscience, 2005, Volume: 132, Issue:2 Topics: Action Potentials; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Mice; Nipecotic Acids; Oocytes; Patch-Clamp Techniques; Potassium Chloride; Seizures; Tiagabine; Time Factors; Vigabatrin; Xenopus laevis	2005
Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model. Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 372, Issue:1 Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Nipecotic Acids; Oxcarbazepine; Pentylenetetrazole; Seizures; Tiagabine	2005
Seizure activity and off-label use of tiagabine. The New England journal of medicine, 2006, Feb-16, Volume: 354, Issue:7 Topics: Adolescent; Adult; Anticonvulsants; Drug Approval; Drug Interactions; Drug Labeling; Epilepsies, Partial; Humans; Nipecotic Acids; Seizures; Tiagabine	2006
Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice. Inflammopharmacology, 2006, Volume: 14, Issue:5-6 Topics: Animals; Anticonvulsants; Cyclooxygenase 2 Inhibitors; Drug Synergism; Drug Therapy, Combination; Lactones; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Seizures; Sulfones; Tiagabine	2006
[Tiagabine overdose--report of two cases]. Przeglad lekarski, 2007, Volume: 64, Issue:4-5 Topics: Adult; Anticonvulsants; Benzodiazepines; Drug Overdose; Epilepsies, Partial; Female; Humans; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Poisoning; Seizures; Suicide, Attempted; Tiagabine; Treatment Outcome	2007
Seizure-freedom with combination therapy in localization-related epilepsy. Seizure, 2008, Volume: 17, Issue:3 Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Drug Therapy, Combination; Female; Frontal Lobe; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Nipecotic Acids; Occipital Lobe; Oxcarbazepine; Parietal Lobe; Piracetam; Seizures; Temporal Lobe; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid	2008
Lack of tolerance to the anticonvulsant effects of tiagabine following chronic (21 day) treatment. Epilepsy research, 1994, Volume: 19, Issue:3 Topics: Animals; Anticonvulsants; Drug Tolerance; Male; Mice; Motor Activity; Nipecotic Acids; Seizures; Tiagabine; Time Factors	1994
Blockade of GABA uptake with tiagabine inhibits audiogenic seizures and reduces neuronal firing in the inferior colliculus of the genetically epilepsy-prone rat. Experimental neurology, 1994, Volume: 126, Issue:2 Topics: Acoustic Stimulation; Animals; Brain Mapping; Dose-Response Relationship, Drug; Epilepsy; Female; GABA Antagonists; Inferior Colliculi; Male; Microinjections; Neurons; Nipecotic Acids; Rats; Rats, Mutant Strains; Seizures; Tiagabine; Time Factors	1994
Tigabine hydrochloride, an inhibitor of gamma-aminobutyric acid (GABA) uptake, induces cortical depolarizations in vitro. Brain research, 1997, Apr-11, Volume: 753, Issue:2 Topics: Acoustic Stimulation; Aging; Animals; Animals, Newborn; Cerebral Cortex; Electrophysiology; Female; GABA Antagonists; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred DBA; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Seizures; Tiagabine	1997
Antiepileptic approved for adjunctive therapy. The Nurse practitioner, 1998, Volume: 23, Issue:1 Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Aged; Anticonvulsants; Child; Epilepsy; Humans; Middle Aged; Nipecotic Acids; Seizures; Tiagabine; United States; United States Food and Drug Administration	1998
GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. Neuropharmacology, 2000, Volume: 39, Issue:12 Topics: Acoustic Stimulation; Anesthesia; Animals; Anisoles; Anticonvulsants; Carbazoles; Chromatography, High Pressure Liquid; Convulsants; Electroshock; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Inbred DBA; Microdialysis; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Pentylenetetrazole; Piperidines; Seizures; Substantia Nigra; Thalamus; Tiagabine	2000
Two different anticonvulsant actions of tiagabine in developing rats. Epilepsia, 2000, Volume: 41, Issue:11 Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Tiagabine	2000
Non-convulsive status epilepticus induced by tiagabine in a patient with pseudoseizure. Seizure, 2002, Volume: 11, Issue:1 Topics: Adult; Anticonvulsants; Diagnosis, Differential; Electroencephalography; Female; Humans; Nipecotic Acids; Seizures; Status Epilepticus; Tiagabine; Video Recording	2002
The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats. European journal of pharmacology, 1992, Sep-22, Volume: 220, Issue:2-3 Topics: Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Globus Pallidus; Male; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Substantia Nigra; Tiagabine	1992
NNC-711, a novel potent and selective gamma-aminobutyric acid uptake inhibitor: pharmacological characterization. European journal of pharmacology, 1992, Dec-02, Volume: 224, Issue:2-3 Topics: Animals; Anticonvulsants; Astrocytes; Behavior, Animal; Brain; Carbolines; Cells, Cultured; Convulsants; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Neurons; Nicotinic Acids; Nipecotic Acids; Oximes; Pentylenetetrazole; Rats; Seizures; Synaptosomes; Tiagabine	1992
An investigation of the involvement of GABA in certain pharmacological effects of delta-9-tetrahydrocannabinol. Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:3 Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Anticonvulsants; Body Temperature; Cannabidiol; Dronabinol; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine	1991
Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor. European journal of pharmacology, 1991, Apr-24, Volume: 196, Issue:3 Topics: Animals; Anticonvulsants; Carbolines; Clonazepam; Convulsants; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred DBA; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Tiagabine	1991