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alaproclate and Seizures

alaproclate has been researched along with Seizures in 1 studies

alaproclate: specific 5-hydroxytryptamine uptake inhibitors; RN given refers to (DL)-isomer

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Alaproclate and GEA-857 antagonized seizures induced by NMDA, 200 mg/kg subcutaneously at doses similar to those antagonizing the harmaline- and NMDA-induced elevation of cerebellar cGMP."1.30NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857. ( Hu, PS; Ross, SB, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hu, PS1
Ross, SB1

Other Studies

1 other study available for alaproclate and Seizures

ArticleYear
NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857.
    Pharmacology & toxicology, 1997, Volume: 80, Issue:2

    Topics: 4-Aminopyridine; Alanine; Animals; Behavior, Animal; Cerebellum; Convulsants; Cyclic GMP; Drug Inter

1997