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alpha-isopropyl-alpha-methyl-gamma-butyrolactone and Seizures

alpha-isopropyl-alpha-methyl-gamma-butyrolactone has been researched along with Seizures in 2 studies

*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Canney, DJ; Covey, DF; Ferrendelli, JA; Holland, KD; Levine, JA; McKeon, AC1
Covey, DF; Ferrendelli, JA; Holland, KD; McKeon, AC; Peterson, EM; Rothman, SM; Xu, K1

Other Studies

2 other study(ies) available for alpha-isopropyl-alpha-methyl-gamma-butyrolactone and Seizures

ArticleYear
Synthesis and structure-activity studies of alkyl-substituted gamma-butyrolactones and gamma-thiobutyrolactones: ligands for the picrotoxin receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: 4-Butyrolactone; Alkylation; Animals; Anticonvulsants; Brain; Convulsants; Female; Ligands; Mice; Mice, Inbred Strains; Molecular Structure; Neurotoxins; Picrotoxin; Receptors, GABA-A; Seizures; Structure-Activity Relationship

1991
Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.
    Journal of medicinal chemistry, 1994, Jan-21, Volume: 37, Issue:2

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Cells, Cultured; Chloride Channels; Convulsants; Female; Hippocampus; Mice; Models, Molecular; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Spiro Compounds; Structure-Activity Relationship

1994